A 42 years old woman from a dry state who ingested rye for long time presented with complaints of weakness in both lower limbs, nausea and fatigue. Over due course of time, she is completely unable to walk. What is the most likely cause?
Argemone mexicana
Amanita
Ergot alkaloids
Lathyrus sativus
Ans: D. Lathyrus sativus(Ref Park 24/e p682, 23/e p644, 657).This case is suggestive of food adulteration & neurolathyrism.Caused by Lathyrus sativus.Neurolathyrism:Crippling disease of CNS.Features:Characterized by gradually developing spastic paralysis of lower limbs.Mostly in adults consuming pulse, Lathyrus sativus.