Treatment of choice for a patient with gonococcal as well as non-gonococcal urethritis is:
Ceftriaxone 250 mg IM single dose
Cefixime 400 mg oral single dose
Ciprofloxacin 500 mg oral single dose
Azithromycin 2 g oral single dose
Ceftriaxone is DOC for gonococci but is not effective against non gonococcal cause of urethritis like mycoplasma and chlamydia. Azithromycin single dose of 2 g is used for both gonococcal and non gonococcal urethritis. In non gonococcal urethritis, doxycycline can also be used.