A patient comes with pinpoint pupil, salivation, tremors, and red tears. Cholinesterase activity was 30% normal. Probable diagnosis is:
Opium
Organophosphate poisoning
Dhatura
Organochloride pesticide poisoning
Ans.B i.e. Organophosphorus* These are characteristic features of anti-cholinesterase (organophosphate and carbamate) poisoning.* Features of Organophosphate poisoning: - Muscarinic symptoms: Pinpoint pupil, salivation, lacrimation, urination, defecation, gastrointestinal distress, vomiting, bronchospasm, bradycardia. - Nicotinic symptoms: Fasciculations and fibrillations of muscle, tachycardia, tachypnea. - CNS symptoms: Tremors, giddiness, ataxia, coma. - Red tears: Due to accumulation of porphyrin in the lacrimal glands