Which of the following is clinical use of tafenoquine?
Radical cure of Plasmodium vivax
Prophylaxis of malaria in pregnancy
Treatment of severe falciparum malaria
Treatment of endemic malaria in children < 2 years
Radical cure - About 8-30% P.v. cases relapse due to persistance of exoerythrocytic stage. Drugs which attack this stage (hypnozoites) given together with a clinical curative achieve total eradication of the parasite from the patient's body. Drug of choice for radical cure of vivax and ovale malaria is: * Primaquine 15 mg daily for 14 days * Tafenoquine is a new long-acting exoerythrocytic schizontocide, has been developed as a single dose anti-relapse drug for vivax malaria.