Asymptomatic hep B is common in 2-3% normal population, but there is increased risk of transmission into hepatocellular carcinoma. Why?
Inability to induce inflammation to remove the organism
High level of transaminases
High rate of proliferation of virus
Integration of viral DNA with host DNA
Option A- Explanation for carrier stage Option C- Refers to high infectivity of the virus so basically higher chances of infection but not cancer. Option D- This leads to inhibition of apoptosis so might cause cancer of liver (HCC)