Gene not involved in SCID
BTK
ZAP70
IL2RG
JAK3
BTK gene is involved in Buon's disease or X linked agammaglobulinemia. Most cases of X linked Severe combined immunodeficiency (SCID) are due to mutations in IL2RG gene. Other mutations are defective enzyme production in Adenosine deaminase and mutations in ZAP -70 which causes defective T cell signalling which causes combined immunodeficiency and mutation occurs in JAK-3.