Mutation seen in sickle cell anemia:
Point
Inseion
Deletion
Frame shift
Sickle-cell anemia Due to a single base alteration Point mutation Glutamate at the 6th position of b-chain of haemoglobin is replaced by Valine. UCA (serine) UCU (Serine) CCA (Proline) UAA (Stop codon) Silent mutation Mis-sense mutation Non sense Mutation