What is the drug of choice for precocious pubey in girls?
GnRH analogues
Cyproterone acetate
Danazol
Medroxyprogesterone acetate
Ans: A. GnRH analogues(Ref- .Shaw 16/e p59).Precocious pubey - Treatment:Depends on cause.Primary treatment goal:Enable child to grow to a normal adult height.GnRH & Medroxy progesterone acetate.GnRH agonists:Doc regardless of cause.DOC for halting premature sexual development.Effective in children with organic brain lesions causing central precocious pubey.Effective in identification of hypothalamic hamaoma (precocious pubey - only manifestation)