Hepatic First pass metabolism will be bypassed by the foltowing routes of drug adminisration excePt?
Oral
Intravenous
Sublingual
Intradermal
Ans: A. OralRef: Goodman & Gilman, I3'h ed., pg. 16-17 and sharma & sharms's Principles of Pharmacologt, 3'd ed., pg. I8-20Oral route has ceain disadvantages notably the 1st pass metabolism in liver before reaching the systemic circulation.