Stoppage of which of the following drugs can result in anxiety and insomnia causing discontinuation syndrome?
Venlafaxine
ImiPramine
Valproate
OlanzaPine
Ans: A. VenlafaxineRef: Katzung, I3'h ed., pg. 524-525 and Goodman & Gilman, l3'h ed-, pg. 27372.Sudden withdrawal of Shoer acting antidepressants paicularly SSRIs (paroxetine and seraline) and SNRI (venlafaxine) can lead to discontinuation syndrome and troublesome side effects.These symptoms may include dizziness, headache, nervousness, nausea, anxiety and insomnia.Out of the options provided Venlafaxine is the best answer.