Treatment of simple endometrial hyperplasia with atypia in 45 yr female:
Hysterectomy
Progestin
Mirena
Postmenopausal women
Risk of malignancies Management Simple Hyperplasia without Atypia- 1% Complex Hyperplasia without Atypia- 3% Progestin Therapy Simple Hyperplasia with Atypia- 8% Complex Hyperplasia without Atypia - 29% Hysterectomy Hysterectomy is the best treatment at any age with atypical endometrial hyperplasia because of the risk of invasive cancer.