Which of the following drugs is not used in detoxifica-tion of chronic alcoholics?
Flumazenil
Disulfiram
Acamprosate
Naltrexone
Ans: A. Flumazenil(Ref: Goodman Gilman 12/e p468; Kaaung 13/e p3 7 7, 394, 12/e p381, 399; KDT 6/e p385; Harrison 19/e p2727, 8/c 1)2727)Flumazenil:GABAa receptor antagonist.Used intravenously to treat benzodiazepine overdoses.Help reverse anesthesia.Not used in alcohol detoxification.Rest given drugs have a role in alcohol detoxification.