A new marker for mantle cell lymphoma especially useful in Cyclin DI negative cases is:
SOX 11
Annexin V
MYD88
ITRA I
Answer- A. SOX 11SOXII expression h a highly specific for mantle cetl lymphoma and identifies the cyclin Dl-negative subtype.Mantle Cell Lymphoma (MCL)Immunophenotype:CD20 CD79a & PAX-5 positive establish B lineageCD5, CD43, FMC-7, cyclin Dl & SOX11 positiveSurface IgM & IgD positiveCDS+ve & CD23 -ve which help to distinguish it from CLL/SLL.