Which hormone has permissive role in pubey?
Leptin
GnRH
Insulin
GH
Pubey means the onset of adult sexual life. Pubey is caused by a gradual increase in GnRH secretion by the pituitary, beginning around 8th year of life. In male and females, the infantile pituitary gland & ovaries are capable of full function if they are appropriately stimulated. However, for reasons not understood, the hypothalamus does not secrete significant quantities of GnRH during childhood. At pubey, the hypothalamus stas secreting pulsatile GnRH, which initiates the other cascading events leading to maturity of the sexual organs and pubey.