A 6 year old patient with anemia, on electrophoresis shows HbF of 90% and HbA2 of 3%. Which of the following will be seen on peripheral smear
A,B
A,C
B,C
ABC
The peripheral smears given shows: A - Target cell B - Howell jolly bodies C - Poikilocytosis. - All these features are characteristic to b- Thalassemia major. - Best investigation for the diagnosis of any kind of hemoglobinopathy-HPLC (High Performance Liquid Chromatography)