One of the many mechanisms of adverse events is its increased binding to secondary targets, usually proteins. With respect to the primary target, the secondary target:
Should be present in the same tissue as the primary target
Should have similar binding sites
Should have absolutely identical secondary structure
Should have a similar primary structure
Ans. b. Should have similar binding sites (Ref: vvww'plosone'org)Secondary site compared to the primary site has the same sequence of binding site.