For which of the following is PPV-23 is most beneficial:
Cystic fibrosis patient
Sickle cell anemia patient
Patient with recurrent rhinitis and sinusitis
Child less than 2 years
Repeated microinfarction can destroy tissues having micro vascular beds prone to sickling. Thus splenic function is frequently lost within 18-36 months of life causing susceptibility to infection paicularly by pneumococci. So ( PPV-23) polysaccharide pneumococcal vaccine is beneficial in sickle cell anemia.