A child born with multiple congenital defect including cleft palate, neural tube defect, atrial septal defect and microcephaly which of the following drug is used by mother during pregnancy:
Erythromycin
Isotretinoin
Ibuprofen
Metronidazole
Friends, Remember CNS anomaly (NTD) + CVS anomaly + facial defects are seen with the use of isotretinoin.