10 year old present with ankle pain. X-ray has Lytic Lesion with sclerotic rim at calcaneum. Following HPE findings were seen. What is your diagnosis:
Eumycosis
PVNS
Ochronosis
Hemophilic pseudotumar
X-ray shows multiple lytic lesion. Histopathology shows cells with brown-color deposits, hemosiderin. * Ochronosis: Usually presents with blackening of urine.* Pigmented villo-nodular synovitis (PVNS): is an aggressive disorder arising from synol joints predominantly in the knee. It shows area of synol proliferation with histology showing hemosiderin stained giant cells.* Eumycosis: Commonly found in foot. Presents with sinuses. It shows Dot in circle sign. X-rays shows multiple bone cavities and progressive bone destruction.* Hemophilic pseudotumor: Usually found in ankle joint. Histopathology shows hemosiderin deposit due to haemorrhage.