Panacea also had four brothers -- Podaleirus, one of the two kings of Tricca, who was skilled in diagnostics, and Machaon, the other king of Tricca, who was a master surgeon (these two took part in the Trojan War until Machaon was killed by Penthesilea, queen of the Amazons) ; Telesphoros, who devoted his life to serving Asclepius ; and Aratus, her half-brother, who was a Greek hero and the patron/liberator of Sicyon.