Let's get this math done. We have 332233 and 88373, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 3 and the borrow 0 from 3 in column 1 and get 0.
0 is the first digit of our result.

Step 2: We'll start by subtracting the digit 7 and the borrow 0 from 3 in column 2 and get -4.
We add -4 to 10 and get 6 as the next digit of the result.

Step 3: We'll start by subtracting the digit 3 and the borrow 1 from 2 in column 3 and get -2.
We add -2 to 10 and get 8 as the next digit of the result.

Step 4: We'll start by subtracting the digit 8 and the borrow 1 from 2 in column 4 and get -7.
We add -7 to 10 and get 3 as the next digit of the result.

Step 5: We'll start by subtracting the digit 8 and the borrow 1 from 3 in column 5 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 3 in column 6 and get 2.
2 is the next digit of our result.

So, 332233 - 88373 = 243860.