Using COC(=O)c1cc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nn2c1 to produce Nc1ccc(-c2nc(N3CCOCC3)c3cc(C(=O)O)cn3n2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.