Using COC(OC)OC, Nc1ccc(F)cc1Nc1nc(Cl)c2[nH]c(=O)n([C@@H]3CCOc4c(F)cccc43)c2n1 to produce O=c1[nH]c2c(Cl)nc(-n3cnc4ccc(F)cc43)nc2n1[C@@H]1CCOc2c(F)cccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.