Using COc1ccc(B(O)O)c(C)c1, Cc1nc(-c2cnn(C)c2Br)c2c(N3CCC3)ncnn12 to produce COc1ccc(-c2c(-c3nc(C)n4ncnc(N5CCC5)c34)cnn2C)c(C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.