Using O, COCc1n[nH]c2cc(Nc3nc4cccc(CN5CCNC(=O)C5)n4n3)ccc12 to produce COCc1n[nH]c2cc(Nc3nc4cccc(CN5CCNCC5=O)n4n3)ccc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.