Using COc1ncc(Br)cc1C, O=C(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(F)(F)F to produce COc1ncc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)cc1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.