Using COC(=O)[C@@H](N)C(C)C, Cc1cc(NC(=O)Nc2cc(C)nc3ccccc23)c2ccccc2n1 to produce Cc1cc(NC(=O)N[C@H](C(=O)O)C(C)C)c2ccccc2n1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.