Using COc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)C)CC1, Oc1ccc(Br)cc1F to produce COc1c(Oc2ccc(Br)cc2F)ncnc1OC1CCN(C(=O)OC(C)C)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.