Using COC[C@@H]1NCCN(Cc2ccc3c(N)ncnc3c2)C1=O, N#Cc1cccc(C=CC(=O)O)c1 to produce COC[C@H]1C(=O)N(Cc2ccc3c(N)ncnc3c2)CCN1C(=O)C=Cc1cccc(C#N)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.