Using COC(=O)Oc1cc(Nc2ncnc3cc(OCCn4ccnc4)c(OC)cc23)c(F)cc1C to produce COc1cc2c(Nc3cc(O)c(C)cc3F)ncnc2cc1OCCn1ccnc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.