Using COC(=O)c1nc(-c2ccc(Cl)c(OC)c2F)nc2ncn(C)c12 to produce CNc1c(N)nc(-c2ccc(Cl)c(OC)c2F)nc1C(=O)O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.