Using COCCl, Cc1nnc(-c2ccc3occ(-c4cn[nH]c4)c3c2)o1 to produce COCn1cc(-c2coc3ccc(-c4nnc(C)o4)cc23)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.