Using CC(C)C[C@@H](C(=O)O)N(C)CC1=C(C=O)Oc2cccc(Cl)c2C1, COC(=O)c1ccc(N)nc1 to produce COC(=O)c1ccc(NC(=O)[C@H](CC(C)C)N2CC3=C(Oc4cccc(Cl)c4C3)C2=O)nc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.