Using CCOC[C@H](Oc1ncnc2c1cnn2-c1ncc(Cl)cc1C(F)(F)F)C(=O)OC to produce CCOC[C@H](Oc1ncnc2c1cnn2-c1ncccc1C(F)(F)F)C(=O)OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.