Using COc1ccc(F)c(CCN(CC(OC)OC)C(=O)C(F)(F)F)c1 to produce COc1ccc(F)c2c1C=CN(C(=O)C(F)(F)F)CC2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.