Using COC(=O)c1sc(C(=O)NCc2cccc3[nH]ncc23)cc1C#N to produce N#Cc1cc(C(=O)NCc2cccc3[nH]ncc23)sc1C(=O)O, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.