Using COC(=O)C1CCCC(NC(=O)N2CCN(c3cc(N)nc4cc(Cl)ccc34)CC2)C1 to produce Nc1cc(N2CCN(C(=O)NC3CCCC(C(=O)O)C3)CC2)c2ccc(Cl)cc2n1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.