Using Cc1nn(-c2cc(Oc3ccc(O)cc3Cl)c(Cl)cc2Cl)c(=O)n1C(F)F, COC(=O)C(C)Br to produce COC(=O)C(C)Oc1ccc(Oc2cc(-n3nc(C)n(C(F)F)c3=O)c(Cl)cc2Cl)c(Cl)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.