Using O=Cc1ccco1, Nc1cccc2c1CN(C1CC(O)C(=O)NC1=O)C2=O to produce O=C1NC(=O)C(N2Cc3c(NCc4ccco4)cccc3C2=O)CC1O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.