Using Cc1nc(C(F)(F)F)ccc1CO, COC(=O)Cc1csc2cc(O)cc(C)c12 to produce COC(=O)Cc1csc2cc(OCc3ccc(C(F)(F)F)nc3C)cc(C)c12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.