Using c1cnc2ccc(Cn3nnc4ncc(N5CCC6(CO6)C5)nc43)cc2c1, CN to produce CNCC1(O)CCN(c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)C1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.