Using COC(=O)CC1CCC(c2ccc(-c3ccc(Nc4ccc(C(F)(F)F)nc4C)nc3)cc2)CC1 to produce Cc1nc(C(F)(F)F)ccc1Nc1ccc(-c2ccc(C3CCC(CC(=O)O)CC3)cc2)cn1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.