Using O=Cc1ccc(B(O)O)o1, COC(=O)c1cnc(N2CCc3[nH]c4ccc(Br)cc4c3C2)nc1 to produce COC(=O)c1cnc(N2CCc3[nH]c4ccc(-c5ccc(C=O)o5)cc4c3C2)nc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.