Using COC(=O)[C@@H]1C[C@H](O)CCN1C(=O)OC(C)(C)C, COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O to produce COC(=O)[C@@H]1C[C@@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CCN1C(=O)OC(C)(C)C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.