Using NCCN, O=C(C(=O)c1ccnc(F)c1)c1cccc(C(F)(F)F)c1 to produce Fc1cc(-c2nccnc2-c2cccc(C(F)(F)F)c2)ccn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.