Using O=C(CCl)Nc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1O, C#CCBr to produce C#CCN1C(=O)COc2ccc(-c3ncc(C(F)(F)F)cc3Cl)cc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.