Using COc1ccc(-c2nc3ccccc3s2)cn1, Fc1cc(CBr)ccc1Cl to produce O=c1ccc(-c2nc3ccccc3s2)cn1Cc1ccc(Cl)c(F)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.