Using c1cncc(C2CCNC2)c1, COc1ccc(-c2nocc2C(=O)O)cc1Cl to produce COc1ccc(-c2nocc2C(=O)N2CCC(c3cccnc3)C2)cc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.