Using O=Cc1cnc2c(c1)CCC(=O)N2, COc1ccc2nccc([C@@H](O)CN3CCC(N)CC3)c2n1 to produce COc1ccc2nccc([C@@H](O)CN3CCC(NCc4cnc5c(c4)CCC(=O)N5)CC3)c2n1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.