Using CCOc1ccc(F)c(-c2cc(C)nc(C#CC[C@@]3(N)CCN(C)C3=O)n2)c1 to produce CCOc1ccc(F)c(-c2cc(C)nc(C3=N[C@]4(CC3)CCN(C)C4=O)n2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.