Using COc1ncnc(Cn2cc(C(=O)O)c3ncc(C)cc32)c1C, NCC(F)F to produce COc1ncnc(Cn2cc(C(=O)NCC(F)F)c3ncc(C)cc32)c1C, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.