Using C1COCCN1, COc1ccc(C2CCOCC2)c2sc(NC(=O)c3ccnc(Br)c3)nc12 to produce COc1ccc(C2CCOCC2)c2sc(NC(=O)c3ccnc(N4CCOCC4)c3)nc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.