Using COC(=O)CCc1nc(-c2cc(C#N)cc(C(F)(F)F)c2)co1 to produce N#Cc1cc(-c2coc(CCC(=O)O)n2)cc(C(F)(F)F)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.