Using C[C@]12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCC[C@@H]2C=O, COC(=O)c1ccc(I)s1 to produce COC(=O)c1ccc(C(O)[C@H]2CCCC3=Cc4c(-c5ccc(F)cc5)ncn4C[C@@]32C)s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.