Using Cc1nc2ccc(Br)cc2n1-c1ncnc(N)n1, C#C[C@@](C)(O)c1cc(C)on1 to produce Cc1cc([C@](C)(O)C#Cc2ccc3nc(C)n(-c4ncnc(N)n4)c3c2)no1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.