Using COC(=O)c1cc2c([nH]1)C(c1cccc(C#N)c1)CC2 to produce N#Cc1cccc(C2CCc3cc(C(=O)O)[nH]c32)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.