Using O=C1c2ccccc2C(=O)N1CCCCBr, Nc1ncnc2nc[nH]c12 to produce Nc1ncnc2c1ncn2C=CCCN1C(=O)c2ccccc2C1=O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.