Using COC(=O)CN[C@@H]1CCc2c(-c3cnc(-c4ccc(OC(C)C)c(C#N)c4)s3)cccc21 to produce CC(C)Oc1ccc(-c2ncc(-c3cccc4c3CC[C@H]4NCC(=O)O)s2)cc1C#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.