Using C1O[C@@H]2CN[C@H]1C2, CCOC(=O)c1nnc2c(Cl)cc(C(F)(F)F)cn12 to produce O=C(c1nnc2c(Cl)cc(C(F)(F)F)cn12)N1C[C@@H]2C[C@H]1CO2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.