Using COC(=O)c1cc(Cl)c2cncn2c1N1CCN(C(=O)OC(C)(C)C)CC1 to produce CC(C)(C)OC(=O)N1CCN(c2c(C(=O)O)cc(Cl)c3cncn23)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.