Using COc1cc2ncnc3c2c(c1OC)CC(O)N3c1cccc(Br)c1 to produce COc1cc2ncnc3c2c(c1OC)C=CN3c1cccc(Br)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.