Using C#C[C@H]1CCC(=O)N1Cc1ccc(OC)cc1OC, CC(C)(C)c1ccc(I)cc1 to produce COc1ccc(CN2C(=O)CC[C@@H]2C#Cc2ccc(C(C)(C)C)cc2)c(OC)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.