Using CCOC(=O)c1c(C)[nH]c2c(-c3cc(C(F)F)ccc3OCC3CC3)ncnc12 to produce Cc1[nH]c2c(-c3cc(C(F)F)ccc3OCC3CC3)ncnc2c1C(=O)O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.