Using COC(=O)[C@@H]1CC(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)CC2)CN1 to produce Cc1[nH]c(C(=O)NC2CCN(C3CN[C@H](C(=O)O)C3)CC2)c(Cl)c1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.