Using COC(=O)Cc1ccccc1CC1NCCc2cc(OC)c(OC)cc21 to produce COc1cc2c(cc1OC)C(Cc1ccccc1CC(=O)O)NCC2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.