Using COC(=O)c1ccc(CN2Cc3c(cc(OC)c(OC)c3Br)C2=O)cc1 to produce COc1cc2c(c(Br)c1OC)CN(Cc1ccc(C(=O)O)cc1)C2=O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.