Using C=CC(=O)O, OC[C@H]1O[C@@H](n2c(NCc3cccc(Br)c3)nc3ccccc32)[C@H](O)[C@@H]1O to produce O=C(O)C=Cc1cccc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.