Using Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21, COc1ccc(CO)cc1 to produce COc1ccc(COc2ccn(-c3ccc4nc(C5CC5)n(C)c4c3)c(=O)c2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.