Using O=C1NCc2cc(C(=O)O)c(Nc3ccc(I)cc3F)cc21, C=COCCON to produce C=COCCONC(=O)c1cc2c(cc1Nc1ccc(I)cc1F)C(=O)NC2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.