Using COC(=O)c1cnc(C(C)(C)C)nc1-c1ccc2c(ccn2C)c1 to produce Cn1ccc2cc(-c3nc(C(C)(C)C)ncc3C(=O)O)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.