Using Cc1sc(-c2ccc(C(F)(F)F)cc2)nc1CCO, COC(=O)c1ccc(O)cc1 to produce COC(=O)c1ccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)sc2C)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.