Using COc1ccc2nc(-c3ccc(C(=O)O)cc3Cl)c(C(F)(F)F)nc2c1 to produce O=C(O)c1ccc(-c2nc3ccc(O)cc3nc2C(F)(F)F)c(Cl)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.