Using CCOC(=O)c1csc2nc(N)nc(N3CCN(C(=O)Nc4ccc(OC)cc4)CC3)c12 to produce COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scc(C(=O)O)c34)CC2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.