Using COC(=O)C[C@@H]1COc2cc(O)ccc21, O[C@H]1CCc2c(Br)ccc(F)c21 to produce COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Br)ccc(F)c43)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.