Using C1COCCO1, Brc1cn2ccnc2c(Nc2ccc3[nH]ncc3c2)n1 to produce Nc1cccc(-c2cn3ccnc3c(Nc3ccc4[nH]ncc4c3)n2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.