Using COC(=O)C1Cc2ccc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)c(C)c2C1 to produce Cc1c(-c2noc(-c3cnc(OC(C)C)c(Cl)c3)n2)ccc2c1CC(C(=O)O)C2, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.