Using COC(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4OC)cc3)c2c1C to produce COc1ccccc1Oc1ccc(Nc2c(C#N)cnn3cc(C(=O)O)c(C)c23)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.