Using COc1ccc(CNC(=O)c2cnc3ccc(Cl)nc3c2Nc2ccc(C(C)(C)C#N)cc2)cc1, CCOC(=O)Cl to produce COc1ccc(Cn2c(=O)c3cnc4ccc(Cl)nc4c3n(-c3ccc(C(C)(C)C#N)cc3)c2=O)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.