Using COC(=O)Cc1ccc(Cc2nc3c(-c4cnc5ccccc5c4)cnn3c(N)c2Br)cc1 to produce Nc1c(Br)c(Cc2ccc(CC(=O)O)cc2)nc2c(-c3cnc4ccccc4c3)cnn12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.