Using COC(=O)C1CCN(C(=S)NN)CC1, CC(=O)c1nn(C)c(-c2ccc3c(c2)CCC3)c1O to produce COC(=O)C1CCN(C(=S)NN=C(C)c2nn(C)c(-c3ccc4c(c3)CCC4)c2O)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.