Using O=Cc1ccco1, CC(C)(C)OC(=O)NC1=NC(C)(c2cc(N)ccc2F)COC1 to produce CC(C)(C)OC(=O)NC1=NC(C)(c2cc(NCc3ccco3)ccc2F)COC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.