Using COc1ccc(CCNc2cc(-c3ccc(F)c(C=O)c3)nc(OC)n2)cc1, COCCN to produce COCCNCc1cc(-c2cc(NCCc3ccc(OC)cc3)nc(OC)n2)ccc1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.