Using O=C(O)C(F)(F)F, CCOC(=O)N1CCN(C(=O)CC(=O)c2ccc3ccccc3c2NCC(=O)OC(C)(C)C)CC1 to produce CCOC(=O)N1CCN(C(=O)CC(=O)c2c(CC(=O)O)cc3ccccc3c2N)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.