Using Cc1cncc(B2OCC(C)(C)CO2)c1, Fc1ccc(-c2cnc3nc(C(F)(F)F)ccn23)cc1Br to produce Cc1cncc(-c2cc(-c3cnc4nc(C(F)(F)F)ccn34)ccc2F)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.