Using COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O to produce COC(=O)c1ncc2c(c1O)CC(c1ccccc1)C(=O)N2Cc1ccccc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.