Using COC(=O)c1ccc(N2CCC(=O)CC2)cc1, O=C(CNC(=O)[C@@H]1CCNC1)Nc1cccc(C(F)(F)F)c1 to produce COC(=O)c1ccc(N2CCC(N3CC[C@@H](C(=O)NCC(=O)Nc4cccc(C(F)(F)F)c4)C3)CC2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.