Using O=Cc1cncnc1, CNc1ncnc(N2CCC3(CC2)C(=O)Nc2ccccc23)c1N to produce Cn1c(-c2cncnc2)nc2c(N3CCC4(CC3)C(=O)Nc3ccccc34)ncnc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.