Using COc1cc2c(Cl)c(C#N)cnc2cc1F, Cn1ccnc1Sc1ccc(N)cc1Cl to produce COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.