Using COc1cc(CNC(=O)c2cc(C(C)=O)nc(C)n2)ccc1F, O=Cc1cccnc1 to produce COc1cc(CNC(=O)c2cc(C(=O)C=Cc3cccnc3)nc(C)n2)ccc1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.