Using CCOC(=O)C[C@@H](C)c1ccc(NC(=O)Cc2cc(OC)c3nc(Nc4ccccc4C)oc3c2)cc1 to produce COc1cc(CC(=O)Nc2ccc(C(C)CC(=O)O)cc2)cc2oc(Nc3ccccc3C)nc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.