Using COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(Cl)nn5)ccc(F)c43)ccc21, CO[Na] to produce COc1ccc(Oc2ccc(F)c3c2CC[C@H]3Oc2ccc3c(c2)OC[C@H]3CC(=O)O)nn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.