Using COCCc1ccc(OC[C@@H]2CO2)cc1, COC(=O)c1ccc(-c2ccc3c(c2)CC[C@H](CN)O3)cc1 to produce COCCc1ccc(OC[C@@H](O)CNC[C@H]2CCc3cc(-c4ccc(C(=O)O)cc4)ccc3O2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.