Using CCC(=O)NC1CCc2cc(N3CCC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)ccc21, CC(=O)O to produce CCC(=O)NC1CCc2cc(N3CCC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3=O)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.