Using CCOC(=O)CC(=O)c1ccc2c(cnn2CC)c1, Nc1nc(-c2ccc(F)cc2)n[nH]1 to produce CCn1ncc2cc(-c3cc(=O)n4nc(-c5ccc(F)cc5)nc4[nH]3)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.