Using COc1ccc2c(=O)n(CC(O)CO)c(C#N)c(-c3cccc(F)c3)c2c1 to produce COc1ccc2c(=O)n(CC=O)c(C#N)c(-c3cccc(F)c3)c2c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.