Using COC(=O)c1cc(C#N)cc(Oc2cncnc2)c1, Nc1ccc(F)cn1 to produce N#Cc1cc(Oc2cncnc2)cc(C(=O)Nc2ccc(F)cn2)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.