Using COC(=O)C1CCN(C(c2ccc3cc(OC)ccc3c2)C(F)(F)F)CC1 to produce COC(=O)C1CCN(C(c2ccc3cc(O)ccc3c2)C(F)(F)F)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.