Using COc1ccc(-n2nnnc2-c2cc(Br)cnc2N)c(F)c1F to produce Nc1ncc(Br)cc1-c1nnnn1-c1ccc(O)c(F)c1F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.