Using COC(=O)c1ccc(-c2ccc(C(C)C(O)(c3ccnc(C)c3)C(F)(F)F)c(Cl)c2)nc1 to produce Cc1cc(C(O)(C(C)c2ccc(-c3ccc(C(=O)O)cn3)cc2Cl)C(F)(F)F)ccn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.