Using COc1nnc(OC)c2cc(C(=O)Nc3cc(C(F)(F)F)ccn3)ccc12 to produce COc1nnc(O)c2cc(C(=O)Nc3cc(C(F)(F)F)ccn3)ccc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.