Using COC(=O)c1cn(-c2cccnc2)c(-c2ccc(NC(C)=O)cc2)cc1=O to produce Nc1ccc(-c2cc(=O)c(C(=O)O)cn2-c2cccnc2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.