Using Cc1nc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3cc(C#N)cc(C=O)c3)c2F)[nH]1 to produce Cc1nc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3cc(C#N)cc(CO)c3)c2F)[nH]1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.