Using COC(=O)C1C[C@@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CN1C to produce COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@@H]1CC(C(=O)O)N(C)C1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.