Using COC(=O)c1cc(Oc2nccs2)cc(-c2ccc(C)cc2C#N)c1 to produce Cc1ccc(-c2cc(Oc3nccs3)cc(C(=O)O)c2)c(C#N)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.