Using COC1=N[C@@H](C(C)C)C(OC)=NC1, Fc1cc(C(F)(F)F)ccc1CBr to produce COC1=N[C@H](Cc2ccc(C(F)(F)F)cc2F)C(OC)=N[C@H]1C(C)C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.