Using COC(=O)c1ccc(O)nc1, OCc1c(-c2ccccc2)noc1C(F)(F)F to produce COC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.