Using COC(=O)c1ccc(-c2c(Cl)sc3[nH]c(=O)c(C#N)c(O)c23)cc1 to produce N#Cc1c(O)c2c(-c3ccc(CO)cc3)c(Cl)sc2[nH]c1=O, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.