Using C=Cc1ccc(C(=O)OC)[nH]1, CC(C)(C)C(=O)Nc1nc(O)c2cc(Br)cnc2n1 to produce COC(=O)c1ccc(C=Cc2cnc3nc(NC(=O)C(C)(C)C)nc(O)c3c2)[nH]1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.