Using COc1cc(C(F)(F)F)nc2c(N3CCC4(CC3)OCCO4)ccc(F)c12 to produce COc1cc(C(F)(F)F)nc2c(N3CCC(=O)CC3)ccc(F)c12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.