Using O=C(Nc1ccc(F)cc1)c1ccc(S)nc1, COc1ccc(Br)c(CBr)c1 to produce COc1ccc(Br)c(CSc2ccc(C(=O)Nc3ccc(F)cc3)cn2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.