Using Cc1nc2c(Cl)ccc(O)c2c(C)c1Cc1ccc(Cl)cc1, COC(=O)C(C)Br to produce COC(=O)C(C)Oc1ccc(Cl)c2nc(C)c(Cc3ccc(Cl)cc3)c(C)c12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.