Using Fc1cccc(CCBr)c1, N#Cc1ccc(CNS(=O)(=O)CCN2CC3CNCC(C2)O3)cc1 to produce N#Cc1ccc(CNS(=O)(=O)CCN2CC3CN(CCc4cccc(F)c4)CC(C2)O3)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.