Using C1COCCN1, COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5cccnc5F)ccc(F)c43)ccc21 to produce O=C(O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5cccnc5N5CCOCC5)ccc(F)c43)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.