Using COC(=O)CC(=O)C(C)(OC)OC, Cc1nc2cccc(C(=O)CBr)c2nc1NC(C)(C)C to produce COC(=O)C(CC(=O)c1cccc2nc(C)c(NC(C)(C)C)nc12)C(=O)C(C)(OC)OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.