Using O=C=NC(=O)C(Cl)(Cl)Cl, COc1ccc(Oc2ncc(-c3ccc(C(C)N)cc3)s2)cc1 to produce COc1ccc(Oc2ncc(-c3ccc(C(C)NC(N)=O)cc3)s2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.