Using COc1ccc(-c2c3c(nc4c2CCc2ccccc2-4)-c2ccccc2CC3)cc1 to produce COc1ccc(-c2c3ccc4ccccc4c3nc3c2ccc2ccccc23)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.