Using COC(=O)C1CCc2nc(C(C)(C)C(F)(F)F)ccc2C1 to produce CC(C)(c1ccc2c(n1)CCC(C(=O)O)C2)C(F)(F)F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.