Using Nc1c[nH]c2ncc(Br)c(F)c12, COc1ccc(Cn2cc(C(=O)O)cn2)cc1 to produce COc1ccc(Cn2cc(C(=O)Nc3c[nH]c4ncc(Br)c(F)c34)cn2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.