Using COc1cc(C(=O)C=CN(C)C)cc(OC)c1OC, N=C(N)Nc1cccc(OC(F)(F)C(F)F)c1 to produce COc1cc(-c2ccnc(Nc3cccc(OC(F)(F)C(F)F)c3)n2)cc(OC)c1OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.