Using COC(=O)c1cn(-c2ccnc3ccccc23)c2ccc(C)cc12 to produce Cc1ccc2c(c1)c(C(=O)O)cn2-c1ccnc2ccccc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.