Using COc1ccc(-c2nc3cnc(C4CCNC(C)C4)[nH]c-3c2C)cc1 to produce Cc1c(-c2ccc(O)cc2)nc2cnc(C3CCNC(C)C3)[nH]c1-2, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.