Using COCCBr, COc1ccc(CNC(=O)c2ccc3c(c2)C2(C)CCNC(C3)C2C)c(OC)c1 to produce COCCN1CC[C@@]2(C)c3cc(C(=O)NCc4ccc(OC)cc4OC)ccc3C[C@@H]1[C@@H]2C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.