Using CCOC(=O)c1cn(C2CC2)c2cc(-c3cc(C4OCC(C)(C)CO4)cc(OC)c3OC)c(F)cc2c1=O to produce COc1cc(C=O)cc(-c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)c1OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.