Using COC(=O)c1cnc(-c2nc3cc(C#N)cc(C(C)C)c3o2)nc1 to produce CC(C)c1cc(C#N)cc2nc(-c3ncc(C(=O)O)cn3)oc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.