Using N#CC1(C(=O)O)CC1, N[C@@H]1CCC[C@H](Nc2cc(-c3c[nH]c4ncc(F)cc34)ccc2F)C1 to produce N#CC1(C(=O)N[C@@H]2CCC[C@H](Nc3cc(-c4c[nH]c5ncc(F)cc45)ccc3F)C2)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.