Using CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(N3CCC3)c(F)c(C)c2c1=O to produce COc1ccc(Cn2cc(C(=O)O)c(=O)c3c(C)c(F)c(N4CCC4)nc32)c(OC)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.