Using COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(C(C)(C)CO)c(OC)c3)cc12 to produce COc1cc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)ccc1C(C)(C)CO, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.