Using COC(=O)c1ccc(Cl)c2nc3n(c12)CCCN3c1c(OC)nc(C)nc1OC to produce COc1nc(C)nc(OC)c1N1CCCn2c1nc1c(Cl)ccc(C=O)c12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.