Using O=C(O)C(F)F, N#CC=C1CCN(c2ccc(N3C[C@H](CN)OC3=O)cc2F)CC1 to produce N#CC=C1CCN(c2ccc(N3C[C@H](CNC(=O)C(F)F)OC3=O)cc2F)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.