Using Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc(Cl)nc2Cl)o1, C1CCOC1 to produce COc1ccc(-c2nnc(-c3c(-c4ccccc4)noc3C)o2)c(Cl)n1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.