Using Cc1cncc(-c2cc(C(=O)O)c(N3CCCC3)cn2)c1, COc1ccc(CN)nc1OC to produce COc1ccc(CNC(=O)c2cc(-c3cncc(C)c3)ncc2N2CCCC2)nc1OC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.