Using COC(=O)Cc1csc2c(Cl)c(O)cc(Cl)c12, Cn1nc(C(F)(F)F)cc1CO to produce COC(=O)Cc1csc2c(Cl)c(OCc3cc(C(F)(F)F)nn3C)cc(Cl)c12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.