Using COC[C@H](C)Oc1cc(Oc2ccc(C(=O)N3CCN(C)CC3)nc2)cc(-c2ccc(C3=NC[C@H](C)O3)[nH]2)c1 to produce C[C@H]1CN=C(c2ccc(-c3cc(Oc4ccc(C(=O)N5CCN(C)CC5)nc4)cc(O[C@@H](C)CO)c3)[nH]2)O1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.