Using COC(=O)c1nccnc1NC(=O)Cc1c(C(F)(F)F)nn(C)c1OC(F)F to produce Cn1nc(C(F)(F)F)c(-c2c(O)c3nccnc3[nH]c2=O)c1OC(F)F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.