Using N#Cc1ccc(C2CCNCC2)cc1, COCc1nc(Cl)c(-c2cc(C(=O)O)ccc2C)[nH]1 to produce COCc1nc(Cl)c(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)ccc2C)[nH]1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.