Using COC(=O)c1cc2c(N3CCOCC3)nc(-c3cnc(NC(=O)C(C)(C)C)cc3C(F)(F)F)nn2c1 to produce Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)c3cc(C(=O)O)cn3n2)cn1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.