Using COC(=O)CCNc1cc(-c2noc(C)n2)ccc1CNC(=O)c1cc(OC)c(C)c(OC)c1 to produce COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCCC(=O)O)cc(OC)c1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.