Using COC(=O)c1ccc2c(c1)CCN(c1ccc(N3CC[C@@H](N(C)C)C3)c(F)c1)C2=O to produce CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(C(=O)O)ccc4C3=O)cc2F)C1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.