Using COC(=O)c1ccc(C(=O)N2CCN(c3ncccc3N)CC2)nc1 to produce Nc1cccnc1N1CCN(C(=O)c2ccc(C(=O)O)cn2)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.