Using COC(=O)c1ccc(C=Cc2nc3cc(C)c(C)cc3o2)cc1 to produce Cc1cc2nc(C=Cc3ccc(C(=O)O)cc3)oc2cc1C, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.