Using COC(=O)c1cncc(OC(=O)N2CCC(CCc3cccc(C(=O)NCCBr)c3)CC2)c1 to produce COC(=O)c1cncc(OC(=O)N2CCC(CCc3cccc(C(=O)N4CC4)c3)CC2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.