Using NCC1(O)CN2CCC1CC2, Cc1cc(N=C=S)nc(C)c1C#N to produce Cc1cc(NC2=NC[C@@]3(CN4CCC3CC4)O2)nc(C)c1C#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.