Using COCOC(C)(c1cccc(F)c1)c1cc(-c2c[nH]c3ncc(-c4cnn(C)c4)nc23)nc(N)n1 to produce Cn1cc(-c2cnc3[nH]cc(-c4cc(C(C)(O)c5cccc(F)c5)nc(N)n4)c3n2)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.