Using COC(=O)C12CC3CC(CC(N)(C3)C1)C2, O=C(Cl)c1ccccn1 to produce COC(=O)C12CC3CC(CC(NC(=O)c4ccccn4)(C3)C1)C2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.