Using O=C1CCCN1, COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(CCl)cc3)nc12 to produce COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(CN4CCCC4=O)cc3)nc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.