Using O=C1CCOCC1, COc1ccc(CNc2nc3ccc(Br)cc3cc2I)cc1 to produce COc1ccc(CNc2nc3ccc(Br)cc3cc2C2(O)CCOCC2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.