Using CCOC(=O)C(F)(F)Cl, O=C1CSc2ccc(C(=O)NC3CCN(CCOc4cnc5ccc(O)cc5n4)CC3)cc2N1 to produce O=C1CSc2ccc(C(=O)NC3CCN(CCOc4cnc5ccc(OC(F)F)cc5n4)CC3)cc2N1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.