Using COc1cc2c(cc1OC)NCCC2, COc1ccc(C2(C#N)CCC(=O)CC2)cc1OC to produce COc1ccc(C2(C#N)CCC(N3CCCc4cc(OC)c(OC)cc43)CC2)cc1OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.