Using COC(=O)c1ccc(-c2cc(-c3cn(C(F)F)nc3C)cnc2N)cc1F to produce Cc1nn(C(F)F)cc1-c1cnc(N)c(-c2ccc(C(=O)O)c(F)c2)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.