Using Br, COCc1nc2c(Cl)nc3ccc(OCc4ccccc4)cc3c2n1CC(C)C to produce COCc1nc2c(Br)nc3ccc(O)cc3c2n1CC(C)C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.