Using COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(N4CCC(O)C4)nc3OC)cc12 to produce COc1nc(N2CCC(O)C2)ccc1-c1cc2c(C(=O)O)c[nH]c2cc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.