Using COC(=O)c1nc(Cl)c(NC2CCN(c3nc(N)c4cc(OC)c(OC)cc4n3)CC2)nc1N to produce COc1cc2nc(N3CCC(Nc4nc(N)c(C(=O)O)nc4Cl)CC3)nc(N)c2cc1OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.