Using OB(O)c1cccc(C(F)(F)F)c1, COC(=O)c1ncc(Br)cc1C to produce COC(=O)c1ncc(-c2cccc(C(F)(F)F)c2)cc1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.