Using O=C1CCc2c(F)cc(N3CC[C@H](O)C3=O)cc21, Oc1ccc(OC2CC2)nc1 to produce O=C1CCc2c(F)cc(N3CC[C@@H](Oc4ccc(OC5CC5)nc4)C3=O)cc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.