Using O=C(Cl)c1ccncc1, COc1cnc(Oc2cc(C)c(-c3csc(N)n3)c(C)c2)cn1 to produce COc1cnc(Oc2cc(C)c(-c3csc(NC(=O)c4ccncc4)n3)c(C)c2)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.