Using CCOC(=O)c1nc2c(C#N)c(C)c(Br)c(F)c2o1, CNC to produce Cc1c(Br)c(F)c2oc(C(=O)N(C)C)nc2c1C#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.