Using CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23, COC(=O)c1ccc2c(c1)CNC2 to produce COC(=O)c1ccc2c(c1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn4c3c1OCC4C)C2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.