Using COC(=O)c1cc(Cl)nc(N2CCC(NC(=O)c3cc(Br)c(C)[nH]3)CC2)c1 to produce Cc1[nH]c(C(=O)NC2CCN(c3cc(C(=O)O)cc(Cl)n3)CC2)cc1Br, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.