Using COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O, O=C1CCCC1 to produce COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CNC4CCCC4)nc32)[C@H](O)[C@@H]1O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.