Using COC(=O)c1ccc(C=C(C(=O)NC2CC2)c2ccc(C)cc2)cc1 to produce Cc1ccc(C(=Cc2ccc(C(=O)O)cc2)C(=O)NC2CC2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.