Using NC1(C(=O)O)CC1, Cc1cc(C#N)cc2c1NC(c1cccc(Br)c1)CC2(C)C to produce Cc1cc(C#N)cc2c1NC(c1cccc(NC3(C(=O)O)CC3)c1)CC2(C)C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.