Using O=C(Nc1nc2cccc(-c3ccc(O)cc3)n2n1)C1CC1, COc1cccc(CBr)c1 to produce COc1cccc(COc2ccc(-c3cccc4nc(NC(=O)C5CC5)nn34)cc2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.