Using CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(Br)c1, C1CCOC1 to produce C=Cc1cc([C@H](CC)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.