Using COc1cnc(C2CCOCC2)c2sc(N)nc12, O=C(O)c1ccc(F)cc1 to produce COc1cnc(C2CCOCC2)c2sc(NC(=O)c3ccc(F)cc3)nc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.