Using COC(=O)C1CCC(C(O)C#Cc2c(C)nc3ncnn3c2N)CC1 to produce Cc1nc2ncnn2c(N)c1C#CC(O)C1CCC(C(=O)O)CC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.