Using N#Cc1cc(Cl)ccc1F, COC(=O)N1c2ccc(Br)c(O)c2CC[C@@H]1C to produce COC(=O)N1c2ccc(Br)c(Oc3ccc(Cl)cc3C#N)c2CC[C@@H]1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.