Using OB(O)c1ccncc1, COc1cc2nnc(C#N)c(Nc3ccc(C)cc3F)c2cc1Br to produce COc1cc2nnc(C#N)c(Nc3ccc(C)cc3F)c2cc1-c1ccncc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.