Using O[C@@H]1CNC[C@H]1N1CCC(O)(c2ccc(Cl)cc2)CC1, Cc1nc(C(F)(F)F)nc(Cl)c1C to produce Cc1nc(C(F)(F)F)nc(N2CC(O)C(N3CCC(O)(c4ccc(Cl)cc4)CC3)C2)c1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.