Using COC(=O)c1ccc2nc(-c3ccc(OC)cc3)c(N(C)C(C)C)nc2c1 to produce COc1ccc(-c2nc3ccc(C(=O)O)cc3nc2N(C)C(C)C)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.