Using COC(=O)C1CCCn2c(-c3ccnc(Oc4ccccc4)n3)c(-c3ccc(F)cc3)c(=O)n21 to produce O=C(O)C1CCCn2c(-c3ccnc(Oc4ccccc4)n3)c(-c3ccc(F)cc3)c(=O)n21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.