Using Cn1c(Cl)nc(-c2ccncc2)cc1=O, COc1ccc([C@H]2CNCCO2)cc1 to produce COc1ccc([C@H]2CN(c3nc(-c4ccncc4)cc(=O)n3C)CCO2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.