Using C[C@@H]1CN(c2cccc(N)c2C#N)C[C@H](C)O1, CCOC(=O)Cc1nc2cccnc2[nH]1 to produce C[C@@H]1CN(c2cccc3[nH]c(=O)c(-c4nc5cccnc5[nH]4)c(N)c23)C[C@H](C)O1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.