Using COc1cccc(N2CCNCC2)c1, Cc1onc(-c2cccc(C(F)(F)F)c2)c1C(=O)O to produce COc1cccc(N2CCN(C(=O)c3c(-c4cccc(C(F)(F)F)c4)noc3C)CC2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.