Using COC(C)(C)ON, Cc1ccc(-c2nc(CCOc3cccc4c3CCC=C4CCC(=O)O)c(C)o2)cc1 to produce COC(C)(C)ONC(=O)CCC1=CCCc2c(OCCc3nc(-c4ccc(C)cc4)oc3C)cccc21, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.