Using COC(=O)c1ccc2c(-c3cccc(C(F)(F)F)c3)cn(C)c2c1 to produce Cn1cc(-c2cccc(C(F)(F)F)c2)c2ccc(C(=O)O)cc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.