Using COc1ncc(C)cc1-c1nc(NC(=O)C2(c3ccc4c(c3)CCO4)CC2)ccc1C to produce Cc1c[nH]c(=O)c(-c2nc(NC(=O)C3(c4ccc5c(c4)CCO5)CC3)ccc2C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.