Using COC(=O)c1cncc(-c2cnc3c(c2)CCCN3)c1, O=C=NC(=O)c1ccccc1 to produce NC(=O)N1CCCc2cc(-c3cncc(C(=O)O)c3)cnc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.