Using COCC(=O)O, COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1O[C@H]1CCCNC1 to produce COCC(=O)N1CCC[C@H](Oc2cc3ncnc(Nc4cccc(Cl)c4F)c3cc2OC)C1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.