Using O=Cc1cc2c(cn1)OCCO2, COc1ccc2nccc(CCN3C[C@H](CN)[C@H](O)C3)c2n1 to produce COc1ccc2nccc(CCN3C[C@H](CNCc4cc5c(cn4)OCCO5)[C@H](O)C3)c2n1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.