Using c1ncn(C2CCNC2)n1, C[C@H]1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23 to produce C[C@H]1COc2c(N3CCC(n4cncn4)C3)c(F)cc3c(=O)c(C(=O)O)cn1c23, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.