Using O=C(CBr)[C@@H]1CCCO1, COC(=O)c1cc(C(=N)N)c(C)cc1C to produce COC(=O)c1cc(-c2ncc([C@@H]3CCCO3)[nH]2)c(C)cc1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.