Using c1cnn(-c2ccc3c(c2)CC[C@H]3N2CC3(CCNCC3)C2)n1, Cc1ccc(CC(=O)O)nc1 to produce Cc1ccc(CC(=O)N2CCC3(CC2)CN(C2CCc4cc(-n5nccn5)ccc42)C3)nc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.