Using COc1nc(-c2nc3n(n2)CCCCC3(O)c2ccccc2C(F)(F)F)ccc1-n1cnc(C)c1 to produce COc1nc(-c2nc3n(n2)CCCC=C3c2ccccc2C(F)(F)F)ccc1-n1cnc(C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.