Using COC(=O)c1ccc(CCc2coc3nc(N)nc(N)c23)cc1 to produce Nc1nc(N)c2c(CCc3ccc(C(=O)O)cc3)coc2n1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.