Using COC(=O)C(CC(=O)N1CCN(c2ccncc2)CC1)Cc1ccc(OC)cc1 to produce COc1ccc(CC(CC(=O)N2CCN(c3ccncc3)CC2)C(=O)O)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.