Using COC(=O)C(C)(C)Br, CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CN(CC(N)=O)C3)ccc1-2 to produce COC(=O)C(C)(C)N1CC(c2ccc3c(c2)OCCc2sc(-c4ncnn4C(C)C)nc2-3)C1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.