Using O=C(Cl)Cl, COc1ncc(N2CCc3ncnc(O[C@H]4CCNC4)c3C2)cc1C(F)(F)F to produce COc1ncc(N2CCc3ncnc(O[C@H]4CCN(C(=O)Cl)C4)c3C2)cc1C(F)(F)F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.