Using Nc1cc(-c2nc3ccccc3o2)ccc1NCc1ccccn1, COC(C)=N to produce Cc1nc2cc(-c3nc4ccccc4o3)ccc2n1Cc1ccccn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.