Using CCOC(=O)C(=CNC(C)(C)C)C(=O)c1cc(F)c(F)c(OC)c1F to produce CCOC(=O)c1cn(C(C)(C)C)c2c(OC)c(F)c(F)cc2c1=O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.