Using COC(=O)Cc1nc(-c2ccc(Cl)cc2)oc1Oc1cc(C)ccc1C to produce Cc1ccc(C)c(Oc2oc(-c3ccc(Cl)cc3)nc2CC(=O)O)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.