Using COCCNc1ccc(Nc2ncnc(OC3CCN(C(=O)OC(C)C)CC3)c2OC)c(C)n1 to produce COc1c(Nc2ccc(NCCO)nc2C)ncnc1OC1CCN(C(=O)OC(C)C)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.