Using COC(=O)C(CCN1CCC2(CC2)[C@H](O)C1)N1CCN(c2cccc(C(F)(F)F)c2)C(C)C1=O to produce CC1C(=O)N(C(CO)CCN2CCC3(CC3)[C@H](O)C2)CCN1c1cccc(C(F)(F)F)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.