Using COC(=O)C1(OC)CC(C)C(=O)C=C1O, Cc1nc(C(F)(F)F)ccc1C(=O)Cl to produce COC(=O)C1(OC)CC(C)C(=O)C(C(=O)c2ccc(C(F)(F)F)nc2C)=C1O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.