Using CCOC(=O)c1ncc(OC)c2c1CCN(Cc1ccc(OC)cc1)C2=O to produce COc1ccc(CN2CCc3c(C(=O)O)ncc(OC)c3C2=O)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.