Using Nc1onc(-c2ccc(OC(F)(F)F)cc2)c1C(=O)O, COc1cccc(N2CCNCC2)c1 to produce COc1cccc(N2CCN(C(=O)c3c(-c4ccc(OC(F)(F)F)cc4)noc3N)CC2)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.