Using C#CCBr, C[C@H]1COCc2nc3c(N)nc4ccc(O)cc4c3n21 to produce C#CCOc1ccc2nc(N)c3nc4n(c3c2c1)[C@@H](C)COC4, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.