Using CCc1nn(-c2ccccc2)c2nc(C3CCNCC3)[nH]c(=O)c12, Brc1ccncc1 to produce CCc1nn(-c2ccccc2)c2nc(C3CCN(c4ccncc4)CC3)nc(O)c12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.