Using COC(=O)C[C@@H]1C(=O)Nc2cnc(N)nc2N1Cc1ncc(C)c(OC)c1C to produce COc1c(C)cnc(CN2c3nc(N)ncc3NC(=O)[C@H]2CC(=O)O)c1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.