Using O=C(Nc1nc2ccccc2s1)c1cccc2c1CNCC2, COC(=O)c1csc(Cl)n1 to produce COC(=O)c1csc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)n1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.