Using COC(=O)c1ccnc(CN)c1, CC(C)Cn1ncc2cc(Cl)cc(CC(=O)O)c21 to produce COC(=O)c1ccnc(CNC(=O)Cc2cc(Cl)cc3cnn(CC(C)C)c23)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.