Using O=C(Nc1cc[nH]n1)c1ccccc1F, COc1ccc(CBr)c(C(F)(F)F)c1 to produce COc1ccc(Cn2ccc(NC(=O)c3ccccc3F)n2)c(C(F)(F)F)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.