Using O=C1CNCCN1, COc1ccc(-c2cnc(Nc3ccc(C(=O)O)nc3)nc2)cc1 to produce COc1ccc(-c2cnc(Nc3ccc(C(=O)N4CCNC(=O)C4)nc3)nc2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.