Using COC(=O)Cc1ccc(C#Cc2ccc3c(c2)C(C)(C)CN(C2CC2)C3)cc1 to produce CC1(C)CN(C2CC2)Cc2ccc(C#Cc3ccc(CC(=O)O)cc3)cc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.