Using COC(=O)CN1Cc2ccccc2N(CC(=O)Nc2cc(Cl)c(OC)cc2OC)C1=O to produce COc1cc(OC)c(NC(=O)CN2C(=O)N(CC(=O)O)Cc3ccccc32)cc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.