Using COc1ccc(-n2c(C)nc(C(Cl)=C(C=O)c3ccnc(Cl)c3)c2C)cc1C(F)(F)F to produce COc1ccc(-n2c(C)nc(C#Cc3ccnc(Cl)c3)c2C)cc1C(F)(F)F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.