Using CCOC(=O)c1cnc2ccc(Br)cc2c1NC[C@H](C)OC to produce CO[C@@H](C)CNc1c(C(=O)O)cnc2ccc(Br)cc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.