The Analysis of Macrovascular Complications in Patients with Combined Diabetes Mellitus and Diabetes Insipidus according to Register in Republic of Uzbekistan
In this article authors discussed data of register of patients with combined diabetes mellitus and diabetes insipidus established in Republic of Uzbekistan in the department of endocrinology of RSCRMCE. According to the register in the Republic of Uzbekistan in 2010 there were registered 2208 patients with diabetes insipidus (DI), 106 from them — with combined DI and diabetes millitus (DM) that made up 4,8 % from total number of patients (0.1% per 100 000 adult population). In children and adolescents the combination of those pathologies wasn’t observed. It was established that combined DI and DM cause mutual deterioration of clinical manifestations and outcomes of 2 underlying diseases, early onset of vascular complications, as evidenced by the significantly high incidence of cardiovascular events — myocardial infarctions and cerebral strokes.