FEATURES OF EXPERIMENTAL ANIMALS PERITONEUM PATHOLOGICAL CHANGES DEPENDING ON EXOGENOUS NITROGEN MONOXIDE INFLUENCE TIME
In experiment on 27 Wistar rats effect of exogenous nitrogen monoxide influence time on morphological changes in an intact peritoneum is studied. Animals are divided into 3 groups depending on time of peritoneum processing (0,6 sec/cm2, 1,8 sec/cm2 and 3,0 sec/cm2). Influence is timed proceeding from an average surface of a rat abdominal cavity of 200 cm2. It is established that processing of an intact peritoneum by nitrogen monoxide containing gas stream during 0,6 sec/cm2 which doesn´t cause the pathologicalchanges in abdominal organs and a peritoneum in experimental animals is optimum. Longer exposition (1,8 sec/cm2 and 3,0 sec/cm2) leads to the expressed vascular disorders, peritoneum mesothelium damage and desquamation with formation of adhesions.