Diagnostic significance of ovarian cancer markers СА 125 and НЕ4
During the process of study we characterized tumor markers СА 125 and НЕ4 used for diagnostics of ovarian cancer. The use of discriminating level >35 U/ml for СА 125 and >70 pmol/L for НЕ4 (independent of age) enabled 81-89% sensitivity at the early stages of disease. The use of ROMA algorithm implicating concentration of both markers and some other indexes does not allow us to increase the effectiveness of early cancer detection.