Administration of Mexidol in treatment of elderly and senile patients with chronic gastrointestinal diseases combined with atherosclerosis in abdominal aorta and age-related macular degeneration
A prospective, simple, placebo-controlled, randomized study was performed to analyze an action of Mexidol on parameters of lipid peroxidation, state of peripheral blood neutrophils and dynamics of clinical symptoms of gastrointerstinal diseases in elderly and senile patients with atherosclerosis in abdominal aorta. Mexidol-treated patients with age-related macular degeneration without signs of macular edema were examined for visual acuity. The results of the study have showed that Mexidol resulted in similar reduction both of heptane-soluble diene conjugates and activity of neutrophils assessed by spontaneous NBT-test in blood serum. Antioxidant efficacy of Mexidol was accompanied by decreased intensity of abdominal pain in geriatric patients with gastrointestinal diseases combined with atherosclerosis in abdominal aorta. Patients with age-related macular degeneration treated with Mexidol were found to have increased visual acuity.