Proof of the efficacy and safety of the liquid extract from the leaves of Eleutherococcus
Background. Only the roots of the plant are used for the production of eleutherococcus liquid extract. Harvesting the roots usually brings plants to the death, and their ground forces, constituting a significant percentage of the total mass of plant tissues, are not used. Methods. To study the biological activity of the leaf extract of Eleutherococcus in experiments on male mice different types of stress were used: physical stress and debilitating hypodynamic model. Results. Samples “Siberian ginseng leaves (Folia Eleutherococci senticosus)” passed sanitary-hygienic examination for compliance with the “Uniform sanitary and epidemiological and hygienic requirements for goods subject to sanitary-and-epidemiologic supervision (control)” It was confirmed that leaf extract of Eleutherococcus (LD <sub>50</sub> = 18,75 ±0,95 ml/kg) is safe; its protective and stimulating effect at different stress responses was displayed. Conclusions. Studies have confirmed the effectiveness and safety of using leaf Siberian ginseng as a die-tary food supplements. The certificate RU.77.99.11.003.E.023222.06.11 from 10.06.2011.