NONALCOHOLIC STEATOHEPATITIS: PATHOGENESIS, DIAGNOSIS, TREATMENT
Nonalcoholic steatohepatitis (NASH) tends to progress to liver cirrhosis. The diagnosis of NASH is based on elevated transaminase levels in subjects with fatty hepatosis if alcoholism and liver diseases are excluded. Of crucial importance for its treatment is to lose weight, by restricting calorie intake and by increasing physical activity. There is no evidence for the efficiency of drug treatment for NASH. Glitazones and vitamin E are today considered to be the most promising agents.