FEATURES OF MICROBIOTA CONTENT AND INTESTINAL MOTILITY AFTER THE CORRECTION OF EXPERIMENTAL DYSBIOSIS WITH PROBIOTIC AND AUTOPROBIOTIC ENTEROCOCCI
Faster recovery of the microbiota and evacuatorial functions of the colon was observed after the introduction of autoprobiotics (indigenous strains of Enterococcus faecium) and probiotic (E. faecium L-3), groups A and P, respectively, for the correction of intestinal antibiotic-associated dysbiosis (AAD) in Wistar rats. First control group of animals (C 1) received phosphate buffer (p. b.) after the introduction of antimicrobial agents. Second control group (С2) take water and p. b. The weight of the cecum was greater in rats from group C 1, than in group C 2 and in animals from groups A and P. The amplitude of spontaneous contractions of rats colon segment (studied by device for work with isolated organs) of rats from group C 1 was less than that from other animals, but completely recovered only in group P. Direct effect of butyric acid on the colon segment led to the changes similar for the effect of E. faecium L-3 in vivo. The more rapid recovery of motility in the group of P, correlated with the increased amount of Faecalibacterium sp. (which produce butyrate) content in the composition of the intestinal microbiota.