Lektinohistochemical characteristics of the human embryonic heart conducting system cells
Lektinohistochemical properties of cardiomyocytes membranes superficial layer in the nodes of conductive system, atrio-ventricular bundle and Purkinje fibres of the human heart in the period from 4 to 12 weeks of gestation are investigated. It is established, that nodes cells express β-D-galactose-containing glycoconjugates on the cytolemmal surface during 5-8 weeks of embryonic development. Atrio-ventricular bundle consists of cells, which have big quantity of N-acetyl-D-glucosamin and N-acetyl-sialic acid residua in glycocalyx. N-acetyl-D-galactoconjugates are observed on their surface only in embryonic period. The presence of N-acetyl-D-glucosamin, N-acetyl-sialic acid and N-acetyl-D-glucosamin residua in the cellular membrane glycan component is characteristic for Purkinje fibres.