Morphological aspects reactive changes in the cervical tissue rats during vaginal labor
An integrated research with optical microscopy, immunohistochemistry and phase-contrast and transmission electron microscopy revealed two interdependent processes: collagen lysis and collagen genesis in rat cervix during pregnancy and childbirth. Immunohistochemical collagen fibers research revealed collagen type III. It means the increase of collagen III expression during last part of pregnancy and childbirth. The collagen genesis centerpieces are cervix myometrium inner layer small smooth muscle cells. This fact indicates that cervix sphincter smooth muscle cells are well differentiated. The findings may be used to elaborate new approaches to integrated management of pregnancy and childbirth.