Possibilities of using partial agonists of D2, D3-dopamine receptors in clinical practice
The article discusses the mechanism of action of partial agonists of D2, D3 receptors, in particular - the atypical antipsychotic of the last generation - cariprazine. The clinical efficacy of cariprazine and its tolerance profile have been described. A review of the results of experimental and clinical studies on the use of cariprazine in the treatment of schizophrenia, bipolar affective disorder, and pathology is presented.