The efficiency of the methods and modifications of ultrafiltration in cardiopulmonary bypass
During open-heart surgery it is possible to disturbance of the barrier function and the appearance of inflammation in the systemic circulation of inflammatory mediators and pro-inflammatory cytokines, which is realized in the systemic inflammatory response syndrome (SIRS). To prevent the development of the condition, or to reduce the severity of its complications method of mechanical removal of inflammatory mediators and cytokines from the blood of the patient is the most efficient. At the moment, the problem of implementation of the systemic inflammatory response syndrome after surgery using cardiopulmonary bypass quite relevant because of the high frequency of its manifestations and adverse effects [1,8]. This explains the large number of studies aimed at both the study of the pathogenesis of systemic inflammatory response syndrome and the development of new methods to combat this phenomenon and the improvement of systemic inflammatory response syndrome, but special attention is given to the study of methods of modified ultrafiltration and hemofiltration. Further study of the application of ultrafiltration on patients undergoing cardiac surgery heart surgery with the use of bypass is necessary for understanding of the physiology and pathophysiology of systemic inflammatory response syndrome induced by the conduct of bypass, as well as for the subsequent formulation of clinical guidelines for use in cardiac surgery practice. In this article we have tried to consider the most significant results of such studies. A statistical effectiveness analysis of ultrafiltration and modified ultrafiltration methods on fluid balance during surgery with cardiopulmonary bypass was conducted. Statistical analysis shows the effectiveness of ultrafiltration and modified ultrafiltration to remove excess fluid from the bloodstream.