DEVELOPMENT AND INVESTIGATION OF THE PHYTO CREAM ON THE BASE OF EUPHRASIA BREVIPILA
The goal of the research is to validate and develop composition and technology of cream on the base of phyto components of Euphrasia brevipila herb. 3% gel of methyl cellulose (hydrophilic base) on the base of aqueous extract of E. brevipila herb has been chosen as the structure-forming component of cream. Optimal conditions of obtaining of aqueous extract have been studied: the method of maceration is in regime of decoction by the technology of SPh Х, the length of cut is > 0,25 ≤ 7 mm. The content of the hydrophilic complex of biologically active substances in the decoction was: 0,21% of flavonoids, 0,06 % of iridoids and 0,3 % of oxidable substances. Oily extract of Euphrasia brevipila herb has been obtained with the use of bismaceration method. The number of lipophilic components in oily extract of Euphrasia brevipila herb was: 6,8 mg% of chlorophylls and 2,6 mg% of carotenoids. Complex vitamin medicinal drug «Aekol» has been added to the phyto cream in a concentration of 3 %. The composition of phyto cream has been offered and the stability of phyto cream has been studied on the content of biologically active substances, organoleptic characteristics and colloidal stability. Hydrophilic and lipophilic biologically active substances of Euphrasia herb can be of interest as promising components of dermatological production.