Interrelation of proteolysis reactions, antiendotixin immunity and apoptosis markers in the blood serum at radiation therapy with radiomodification
The investigation of 18 patients with head and neck tumors demonstrated that radiation therapy with radiomodification produced more intensive normalization of proteolysis parameters, increase of blood serum TNF-a level and reduction of the indices of humoral and antiendotoxin immunity, when compared with the group of the patients without modification. Normalizing proteolysis parameters and TNF-a level increase can be considered as one of the possible criteria of efficacy of RT with radiomodification, which requires further investigation.