Principles of antimicrobial therapy for acute tonsyllopharyngitis in children taking into account the growing drug resistance of infectious agents
Acute tonsyllopharyngitis (ATP) is a common cause of both medical visits and administration of antibacterial therapy (ABT) in childhood unjustified in many cases, which furthers a growth of drug resistance demonstrated by causative agents of infectious diseases. Most often, ATP in children is caused by viruses, in 15-36% - by group A ß-haemolytic streptococcus (GABS). For deciding about the use of systemic ABT in ATP bacterial analysis or express test for GABS should be performed. In patients with the nonstreptococcal etiology of ATP, administration of local antimicrobial drugs is expedient. One of them is Grammidin -a combined drug containing the antiseptic cetylpirydinium chloride (effective against bacteria, fungi, viruses, and also against microbial biofilms) and the antibiotic Gramicidin C. A high effectiveness and safety of this drug in children has been proven in a series of clinical studies.