Facial pain as a manifestation of diseases of the nose and paranasal sinuses
Diseases of the nose and paranasal sinuses appear as facial pain. Objective: to investigate the mechanism of a relationship between neurogenic and immune reactions in the development of a pain symptom in diseases of the nose and paranasal sinuses. A total of 504 patients with diseases of the nose and paranasal sinuses were examined. In these diseases, an adequate immune response to an infectious agent is shown by a moderate pain symptom. The manifestations of the pain symptom as its absence or severe pain, which are untypical for the diseases of the nose and paranasal sinuses, suggest an impaired immune response.