The functional condition of endothelium of patients with combination of ischemic heart disease and gastroduodenal ulcer disease
The aim of this work is investigation of vessels endothelium functioning at patients with coronary artery disease (CAD) and ulcer disease (UD). Patients of first group (n=76) got a standard eradication therapy (Maastricht-III) during 14 days. Patients of second group (n=36) were treated only by anisecretory therapy (omeprazol). Thord group included patients with CAD without gastroenterological pathology. Estimation of vessels endothelium state was executed by non-invasive method of scrutiny of peripheral arteries endothelium-dependent vasodilatation (EDVD). It was stated, that patients with combination of CAD and UD is characterized by clear endothelium dysfunction, verificated on EDVD. At patients of this group full-fledged eradication therapy leads to normalization of brachial artery EDVD. It confirmed positive effect of Helicobacter pylori eradication on endothelium functional state.