Stress-induced hyperglycemia in patients with acute my­ocardial infarction
The objective of the present research was to reveal the features of acute myocardial infarction in patients with­out violations of carbohydrate metabolism in the anamnesis complicated by the development of hyperglycemia and to create a mathematical model for assessment of the development of Diabetes Mellitus 2 types in the post-myocardial infarction period. Results for examination of 185 patients with acute large-focal myocardial infarction (MI) without previous carbohydrate metabolism disorders are presented in the article. Patients with MI and hyperglycemia (HG) were characterized by more severe systemic inflammation, hemostasis disturbances and changes in the hormonal state than patients without HG. This was associated with more severe MI progression and more prominent changes in structural and functional cardiovascular parameters. The changes in patient outcomes and homeostasis parameters have been revealed depending on the dynamics of glycemia in the acute period of MI. We have developed a mathematical model for assessment of diabetes mellitus onset risks in patients with MI and HG.