Trittico (trazodone) for treatment of sleep disturbances in depression: the results of multicenter study
Efficacy of Trittico (trazodone) was assessed in open-label, multicenter prospective study of patients with depression and insomnia. After 42 days of treatment with Trittico 10-300 mg daily (in the evening), we observed significant (p < 0,05) improvements on Anxiety and Depression Scale, reduced mean scores on sleep quality and daytime sleepiness scales, improvement of night-time sleep and others. High efficacy and good safety of Trittico was marked by patients and physicians.