LEVELS OF ELEMENT COMPOSITION AND METAL-DEPENDENT ENZYMES OF ANTIOXIDANT SYSTEM IN THE BLOOD OF DRUG ADDICTED INDIVIDUALS
The levels of metal-dependent antioxidant enzymes, i.e. superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and concentration of reduced glutathione, sulfur, iron, copper, zinc, selenium were studied in the blood of drug addicted individuals. Inhibition of the above-mentioned enzymes in the background of active bioelements deficiency was revealed. The glutathione peroxidase activity changes were most obvious; it was decreased in addicted individuals by 79% compared to healthy donors and it was confirmed by a decrease of selenium concentration by 50,5%.