INFLUENCE OF MICROORGANISM-PROBIONTS ON THE RESISTANCE TO ANTIBIOTICS OF STRAINS ENT. FECALIS 200, ST. АLBUS ATCC 25923, PR. VULGARIS 192 AND KL. PNEUMONIA 72 IN VITRO
The article explores the influence of supernatants of lacto-acid feeding additive probiotic strains (Chebakov V.P.) based on the microorganisms Lactobacilus acidophilis L-41, Streptococcus termophilus В-41, Bifidobacter bifidum longum Б-41, Propionobacterium acidi-propionicum 76 from 1st to 30th cultivating day on antibiotic susceptibility of E. fecalis 200, St. albus ATCC 25923, Pr. vulgaris 192, Kl. pneumonia 71opportunistic pathogenic microflora. The research has shown the tendency of antibiotic susceptibility increasing of the studied strains after their cultivating with probiotic strains. The researchers observed reducing of the number of high resistant specimens, increasing of the number of low resistant specimens and increase in the duration of their cultivating. When defining antibiotic susceptibility (changes in microorganismstasis) of opportunistic pathogenic microflora the authors observed the lack of this consequence. After contacting with 10 days aged probiotics the researchers found out increase of antibiotic susceptibility (75.0 - 96.0 %) and E. fecalis 200 microorganismstasis (75.0 - 96.0 %). The authors observed the lowest microorganismstasis in Pr. vulgaris 192 (49.3 - 63.4 %) and Kl. pneumonia 72 (50.0 - 53.1 %) after their contacting with 30 days probiotics. Cultivation of St. albus ATCC 25923 with supernatant of 30 days probiotic strains MKD Lactobacillus acidophilus L-41, Bifidobacter bifidum longum Б-41, Propionobacterium acidi-propionicum 76 causes microorganismstasis to antibacterial specimens (73.8-89.2 %) than that of S. enteritidis 182, Ent. fecalis 200, Pr. vulgaris 192 and Kl. pneumonia 72