Dysmenorrhea: Practical Issues of Pathogenesis, Clinical Presentation and Treatment
Purpose of the Paper: To summarize modern knowledge about the etiopathogenesis of dysmenorrhea and to detail approaches to treating this condition. Key Points: Dysmenorrhea is a highly prevalent gynecological disorder that considerably reduces a woman's quality of life. This makes dysmenorrhea an important medical and social issue. It is usually one of the earliest signs of defects in the regulation of the menstrual cycle. Combined oral contraceptives (COC) containing chlormadinone acetate are first-line medications for patients with dysmenorrhea. As shown in numerous studies, they effectively treat dysmenorrhea symptoms by inhibiting the inflammatory enzymes and reducing the synthesis of prostaglandins. Conclusion: In patients with dysmenorrhea, timely and pathogenesis-based treatment helps maintain women's quality of life, improves their emotional and mental health and ensures continued reproductive and general female health.