The study of major metabolic processes and humoral immunity by patients with atopic dermatitis
It has examined 56 patients with atopic dermatitis of different severity. Due to SCORAD (Scoring atopic dermatitis) (Scoring atopic dermatitis) index it were formed 3 groups of patients and control group. By all of patients were studied the level of immunoglobulin E in blood, the concentration of eosinophils in peripherical blood, the basic biochemical blood rates, nitrogen metabolism. The changes of biochemical blood rates were discovered by 63% of patients with atopic dermatitis, which indicates the synthetic and detoxific liver malfunction. It was discovered the reciprocally proportional correlated relationship between blood urea concentration, cholesterol, gammaglutamiltransferase, ammonia and the severity of atopic dermatitis clinical course. It was confirmed direct relationship between the level of immunoglobulin E and high SCORAD indexes. By patients with moderately severe and severe atopic dermatitis clinical course it was registered the insufficient neutralization of nitrogen metabolism products against the background of exacerbation of the pathologic process.