THYROID AND GLUCOCORTICOID STATUS IN PATIENTS WITH NASOPHARYNGEAL CANCER: FEATURES OF THE DYNAMICS UNDER THE INFLUENCE OF CHEMO- AND RADIOTHERAPY
In patients with nasopharyngeal cancer were revealed significant alterations in thyroid and glucocorticoid functions. It was made a comparative evaluation of the impact on the dynamics of the hormonal parameters of two variants in antitumor treatment - developed method automielochemoradiation therapy (AMCRT) and traditional DHT. The treatment was accompanied by the same type in both cases changes in hormone levels (decrease of the concentration of total T3 and TSH and, in some cases, a sharp hypocortizolemia), and typical only to AMCRT (normalization PDF created with pdfFactory Pro trial version www.pdffactory.com of the free T3 level, an earlier normalization of the total T4, less pronounced decrease in the secretion of TSH.)