Role of methicillin-resistant staphylococcus in septic pathology
Introduction. Staphylococcal infections present an important issue of public health, because of their widespread prevalence, and significant health and socio-economic prejudice. During last years, was observed  a significant increase of nosocomial  infections, including septic pathologies, caused  by methicillin-resistant Staphylococcus. Purpose of the study. Studying the situation in Republic of Moldova with methicillin resistant Staphylococcus isolated from the blood. Materials and methods. The study includes the results of bacteriological investigations of blood cultures, collected from patients with septic complications, performed during 2014–2017. The isolation of Staphylococcal  strains and determination of their sensitivity to antibiotics were carried out by using of the classical method  and the automated system VITEK 2 Compact (bioMérieux). Results. From the total number of bacteria isolated from blood, Staphylococcus were isolated in 50,8%, from which 71,11%  were MRS. In 96% of cases, strain of methicillin-resistant Staphylococcus are coagulase-negative staphylococci  (S. epidermidis, S. haemolyticus, S. saprophyticus), and only 4% – are coagulase-positive staphylococci (S. aureus). The isolated strains of methicillin-resistant staphylococci manifested high resistance to almost all antibiotic groups, and 96,3% were considered  to be multi-resistant. Conclusion.  The rate of methicillin-resistant Staphylococcus  strains, isolated from the blood of patients with septic complication, was 71,11%.