EFFECTS OF PROCESS PARAMETERS ON CHARACTERISTICS OF PLGA MICROSPHERES FORMED BY THE MICROFLUIDIC METHOD
It was established, the sizes of PLGA microspheres depends on the flow rates ratio, PLGA concentration in the organic phase, type and concentration of surfactants in the aqueous phase. Increasing PLGA concentration in the organic phase and flow rates ratio (Qo/Qa) allows to obtain microspheres in the size range of 20-65 microns with a narrow size distribution (coefficient of variation from 6% to 9%). The reported study was funded by RFBR, project №19-015-00155.