ARTERIAL HYPERTENSION AND VASCULAR REMODELING IN PATIENTS WITH DIABE- TES MELLITUS TYPE 2 AND DECREASED THYROID FUNCTION
68 patients with diabetes mellitus (DM) type 2 were divided into 2 groups: group I (n = 36) - patients with type 2 diabetes and euthyroidism; group II (n = 32) - patients with type 2 diabetes with subclinical hypothyroidism. For all patients 24-hour monitoring of blood pressure (BP) and ultrasonography measuring of the intima-media complex thickness of the carotid arteries were performed, and the concentration of the vascular endothelial growth factor (VEGF) was determined. The most unfavorable daily profile of BP and significantly higher values of daily systolic, diastolic and pulse BP were observed in patients of group II. Also, in patients with type 2 diabetes and concomitant hypothyroidism, a greater thickness of the intima-media complex of the carotid arteries and a significantly elevated level of VEGF were revealed.