The condition of the cellar immunity and polymorph varieties SNP - 1082 g ->a of the gene IL-10 promotor region in women with recurrent pregnancy lost
We studed the SNP1082 G A of the gene IL-10 promotor region in couples with secondary infertility which was caused by first trimester recurrent pregnancy lost. As a result of studying was determined statistically significant increase of both IL-10 high expression allele frequency (G-allele) and IL-10 high expression genotype frequency (GG-genotype). We suppose that IL-10 gene may be active in pathogenesis of first trimester reccurent pregnancy lost because of immunological disfunction in women