ETIOTROPIC CHEMOTHERAPY EFFICACY IN EYE TUBERCULOSIS AND WAYS OF ITS IMPROVEMENT
Etiotropic chemotherapy results were studied in 66 patients with new-onset eye tuberculosis and in 46 - with relapses. The efficacy of earlier proposed (optimized) treatment methods of newonset patients was confirmed. To treat patients with relapses, a prolonged treatment regimen up to 6-8 months was elaborated and introduced in 2006- 2008. This regimen included systemic treatment with isoniazid, rifampicin, pirozinamid and one of the fluoroquinolones. Local treatment consisted of 5-7 isoniazid courses (periocular injections, electrophoresis, in-between courses - instillation of one of the fluoroquinolones), all this significantly increased the treatment efficacy. Higher efficacy of tuberculous chorioretinitis treatment, in comparison with that of anterior uveitis was demonstrated (р < 0.05). Comparative evaluation of treatment results on dispensary and health station stages is performed, ways to increase treatment efficacy are traced.