RESTORATIVE PROCESSES AND HORMONES (literature review)
Based on the totality of the examined data, it is established that the local outcome of the reparative process is determined by the relationships between the tissue components of the regenerating structure and that the leading factor in this respect is the behavior of cellular elements of mesenchymal origin. The course of reparative regeneration depends on the general physiological conditions of the organism, among which the active principles of the endocrine organs play an important role. The hormone of each peripheral gland has a specificity regarding the effect on reproduction, proliferation and differentiation of cells participating in the implementation of the reparative process in its main phases. Just connective tissue elements and show the most significant variety in their reactions to hormonal influences. Cells of mesenchymal origin provide by their participation, the formation of the basic morphological substrate, which determines and provides the trophic, as well as the supporting framework of developing tissues, and thereby in combination creates the necessary conditions for the proliferation and differentiation of epithelial structures. Already by the reaction of cells evacuating to the area of damage under conditions of certain hormonal effects, one can make a prediction about the further outcome of the reparative process.