The role of infectious and inflammatory factors of extravagant localization on the development of preterm labor
The literature review is devoted to the study of the role of infectious and inflammatory factors of extravagant localization in the etiopathogenesis of preterm labor. It is noted that there is a lot of information about increasing the risk of spontaneous premature birth in women with infectious and inflammatory diseases of the urinary system, periodontal diseases. There are some works on the effect of intestinal dysbiosis on the development of spontaneous premature labor. In contrast, infectious lung diseases (complicated flu, tuberculosis, severe pneumonia) are the cause of induced premature birth due to the severe condition of the mother. The influence of a number of pathogens of extragenital localization on the start and development of inflammatory changes in the tissues of the placenta and amniotic cavity was established. Rehabilitation of foci of chronic infection of extravagant localization at the pregravid stage and vaccination will contribute to the effective prevention of spontaneous and induced premature birth.