CORRECTION OF HYPERHOMOCYSTEINEMIA IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL FAILURE SYNDROME
The aim of our research was to analyze the serum total homocysteine concentration in patients with hemorrhagic fever with renal failure syndrome (HFRS) depending on the forms and stages of the disease with subsequent vitamin therapy. It was revealed that in all studied forms (mild, severe and complicated) the level of homocysteine was increased even during the febrile stage with maximum level during the oliguric stage and subsequent decreased during the diuretic and the convalescent stages. This level remained above the level of control group. In conclusion, vitamin therapy of HFRS led to significant decrease of homocysteine in patients with different forms of this disease.