Daily monitoring of arterial blood pressurewith measurement of stiffness of arterial vessels in hypertensive patients
The purpose of the study is to identify the features of indices of daily monitoring of blood pressure and to evaluate the indicators of stiffness of arterial vessels using a modern daily monitor of blood pressure in male patients with stage I and II hypertension. Materials and methods. The results of the study are based on complex examination of 105 male patients with stage I and II hypertension at the age from 35 to 55 years. Assessment of the total risk of cardiovascular complications was carried out according to the SCORE scale. The median point values of the SCORE scale showed no significant differences between the groups of patients. In the main group it was 1.68 [1,25; 3,52] vs 1,38 [0,86; 2,66] in the control group (p>0.05). Patients of both groups were comparable in cardiovascular risk. Results. The median time index of the SBP in the group of patients with the stage II HT was 73 [65; 81], and it was 73 [72; 76] in the control group. It had a significant difference in comparison with the group of healthy individuals, 31 [30; 33] (p<0.05). A significant increase of the time index of the DBP in the groups of patients in comparison with practically healthy persons was 2.3 times.In the group of patients with the stage II hypertension PWV 9.8 [9.2; 9.9] m/s was significantly higher than in the group of healthy individuals 7.6 [7.2; 7.9] m/s (p<0.05). On the base of that PWV, no significant difference between the control group and the group of healthy individuals was revealed (p>0.05).In statistical processing of the obtained data, we revealed a significant (2.8 times) increase of Aix on the shoulder in the control group in comparison with practically healthy individuals. Increase of this indicator in the main group of patients was by 3.7 times if compared with the group of healthy individuals. High values of Aix in the aorta were registered in the main group (25.8% [12.5; 29.8]). It showed a significant difference with the control group - 9.5% [-10.5; 28.7] (p<0.05).Using the correlation analysis, we revealed interrelations between the indicators of remodeling of arterial blood vessels of elastic and muscular type and the indices of daily monitoring of BP in patients with essential hypertension. We found a positive correlation between the time index of DBP and IMT (R=+0.29, p=0.001), and negative correlation between daily index of DBP and PWV (R=-0.25, p=0.01).