Extragenital, Gynecological and Infectious Pathology as Possible Risk Factors for the Development of Premenstrual Syndrome
Premenstrual syndrome (PMS) is a frequent pathological condition associated with the menstrual cycle. Despite a long history of studying the issue, there is currently no clear theory of the etiology and pathogenesis of PMS and not defined its main causes. The article presents the results of case-control study of risk factors for PMS, which was conducted by questioning women using a specially developed and proven questionnaire. The study involved 1500 women from six federal districts of Russia. Premenstrual syndrome was diagnosed in 939 (62.6%) women. Results of the study revealed that women with PMS had significantly more somatic diseases: diseases of the digestive system (40.7%), neurological (14.9%), urinary (14.2%) systems and menstrual disorders (P < 0.05). In 11.6% of women primary manifestation of PMS was associated with infectious diseases.