THE DEVELOPMENT OF INFLAMMATORY CHANGES IN THE VASCULAR WALL WHEN AN IMBALANCE IN THE SYSTEM OF HEMOSTASIS THE INFUSION OF LOW MOLECULAR WEIGHT HEPARINS IN PATIENTS TRAUMATOLOGIC-ORTHOPEDIC PROFILE
The hemostatic system participates in important life processes: inflammation, reparation of tissues, maintaining homeostasis and other It actively responds to various exogenous and internal changes of the body, may be congenital and acquired functional disorders, which leads to an imbalance in the system. Inflammatory reaction is one of the leading causes in the pathogenesis of cardiovascular diseases, which also causes imbalance in the hemostasis system. An analysis of the results of research of influence of the concentrations of C-reactive protein on the dynamics of coagulation tests on the background of the introduction of low molecular weight heparins. The inflammatory process of the endothelium is the starting point for activation of both platelets and coagulation hemostasis and, consequently, the possible development of thrombosis. The data obtained will provide an opportunity to develop an individual approach NMG patients traumatologic-orthopedic profile that will allow to increase antithrombotic effect, reduce the risk of side effects and complications, reduce the cost of treatment of the patient.