PECULIARITIES OF CIRCADIAN DYNAMICS OF THE ANTIOXIDANT SYSTEM AND LIPID PEROXIDATION IN RATS
The activity of the liver as the central metabolic laboratory of an organism has a clear circadian rhythm due to the de- pendence of the daily flow of metabolic processes in the body. An important linking element of the cellular metabolism of circadian rhythms is the body’s antioxidant system (AOS) activity and lipid peroxidation (LPO). As a result of this research the circadian dependence of the LPO-AOS activity has been determined, however, not all of the components of the AOP sys- tem “work” equivalently during the day. According to the key components of the AOP activity the maximal “sustainability” of AOS is observed in the morning and the minimal - in the evening and at night. No significant sex differences between female-rats and male-rats have been found.