Structural brain organization in mice with cerebral candidosis after treatment with amphotericin B and oxide-dextran composition
The structural changes were analyzed in male CBA line mice brain after treatment with amphotericin B and oxide-dextran during candidosis meningoencephalitis (ATCC 24433 strain). High efficiency of amphotericin B and oxide-dextran composition on destructive and edemal changes, hemocirculatory disturbances and compensatory mechanisms in brain was shown compare to free form of amphotericin B.