MODERN ISSUES OF QUALITY OF LIFE RESEARCH IN HEMATOONCOLOGY
One of the priorities of modern medicine ispatient-centered care. The key aspect of patient-centered care is the patient’s active and centralrole in managing their disease, including theself-monitoring of patient-reported outcomes.Quality of life and symptom assessment is animportant aspect of clinical studies and routineclinical practice in modern hematooncology. Thepeculiarities of quality of life research in hematooncology deal with its methodolody. Modernmethodology of quality of life assessment allowsto measure key aspects of well-being of a patientwith blood cancer and to study changes of his/her physical, psychological and social functioning due to disease and its treatment. The mostimportant areas of application of quality of lifeand symptom research in hematooncology are asfollows: standartization of treatment regimens;evaluation of treatment efficacy; evaluation ofefficacy of new drugs and improvement of theirquality; development of prognostic models; development and evaluation of the efficacy of rehabilitation programs; study of quality of life inpatients in long-term remission; individual monitoring of patient functioning in clinical practicewith evaluation of early and long-term treatmentoutcomes; economic evaluation of treatment outcomes with such approaches as “cost-utility” and“cost-effectiveness”.