A comparative clinical characteristic of hepatitis E and A in a group outbreak
The work presents the results of comparing clinical manifestations of acute hepatitis E and A in elderly individuals in an outbreak of disease. Taking into consideration that a group hepatitis E outbreak was not registered previously at non-endemic territories, the obtained results are of a pioneering character. The authors established the presence of certain specificities in the course of acute hepatitis E as compared with hepatitis A manifested by the significantly more frequent pain and dyspeptic syndromes, and also by preservation of hyperbilirubinemia after normalization of the levels of amino transferase activity. Taking into account of clinical manifestations and differences between acute hepatites E and A is important for early detection of such outbreaks and for subsequent determination of the follow-up tactics in such patients.