THE LETHALITY AMONG NEW TB CASES IN KISHINEV IN DIFFERENT TIME PERIODS
The aim: to study lethality from progressive TB among new TB cases, who died in hospital in different time periods. Materials and methods. We carried out a retrospective analysis of deaths from TB in Kishinev in three time periods conditioned by the epidemiological situation: period 1 - from 2001 through 2003, period 2 - from 2007 through 2009, and period 3 - from 2013 through 2015. In hospital progressive TB caused deaths in 64 (31.7%) cases in period 1, 77 (72%) cases in period 2, and 36 (60%) cases in period 3. Results. Exposure to TB was established in half of the cases. In all the periods TB was mainly detected at patients' referrals. The most cases diagnosed with infiltrative TB had caseous pneumonia. In period 3 we observed the growing number of cases with generalized TB and emergence of extensively drug resistant tB. Among concomitant diseases most common were chronic alcoholism, HIV-infection, chronic hepatitis, anaemia. Two thirds of the cases died during the first month after hospitalization.