Evaluation of a stress reaction and damage of mucosa in an impairment technique of delivery of anesthetic solutions
Administration of local anesthetic is the most required and the most frequently used manipulation during a dental treatment. However, this manipulation, that itself is aimed to eliminating the pain symptom, is often uncomfortable. Analysis of the literature cited in the article demonstrates that the impairment delivery of anesthetic during local anesthesia is one of the most important causes of pain symptoms in the patient. Histological and biochemical evaluation of the severity of stress response and damages of oral mucosa with different modes of administration of anesthetic in laboratory animals were evaluated. The results show that the administration of anesthetic with fast speed causes the development of structural damage periodontal tissue. The results of biochemical studies have demonstrated changes in the level of glucose and enzymes with the rapid introduction of anesthetic, which indicate the presence of severe systemic stress response of the body.