THE INFLUENCE OF SULFIDE BALNEOPELOIDOTHERAPY ON THE COMPONENTS OF METABOLIC SYNDROME AND COGNITIVE BRAIN FUNCTION
The aim of the study was to assess the clinical effectiveness of sulphide balneopeloidotherapy on the basis of Klyuchi resort with patients suffering from metabolic syndrome without and with the presence of chronic cerebral ischemia. Material and methods of the investigation. There have been examined 59 middle-aged patients at 63.0 [56.0-69.0] years old. The patients were divided into 3 groups: the 1st group included 27 patients with metabolic syndrome and chronic cerebral ischemia who received complex sulphide balneopeloidotherapy at "Klyuchi" resort, the2nd group included 14 patients with symptoms of metabolic syndrome and chronic cerebral ischemia who were in the spa without mudtherapy to assess the influence of general climatic factors and the 3rd group included patients with metabolic syndrome without chronic cerebral ischemia who received sulphide balneopeloidotherapy. The examination complex consisted of general-medical, clinical-neurological, neuropsychological and laboratory-instrumental methods with inclusion of neurotrophic factors. Results. After the spa treatment by natural factors in resort “Klyuchi”, the patients who used complex sulphide balneotherapy had a statistically significant increase in the level of cerebral neurotrophic factor (BDNF) in the blood serum associated with the decrease of all subjective complaints, improvement of cognitive functions. The patients with metabolic syndrome without chronical brain ischemia had an improvement of daily monitoring of blood pressure and fats. Conclusion. There has been substantiated the expediency of inclusion some courses of sanatorium-and-spa treatment with the use of hydrogen sulphide baths in combination with applications of mud sulphide mud in the treatment and rehabilitation of patients suffering from cognitive impairment of mild and moderate degree in the course of chronic cerebral ischemia and metabolic syndrome.