Association of angiotensine-converting enzyme's gene and left ventricle hypertrophy in patients with arterial hypertension. Influence of sex
222 patients with essential hypertension were examined. Echocardiography with estimation of myocardial mass of left ventricle and identification of I/D polymorphism of angiotensine-converting enzyme gene were performed in all patients. Proved that allele D of this gene was associated with left ventricle hypertrophy in women predominantly. Besides, it was found that presence of this allele is related to the presence of concentric hypertrophy of left ventricle and its diastolic dysfunction.