The effect of immunomodulator "Licopid" on mast cells population in the "artherosclerotic" heart
The morphometric evaluation of the activity was carried out in population of mast cells of the heart in experimental rats with exogenous hypercholesterolemia and immunomodulation by «Licopid» with different duration of the course of administration. It was shown that hypercholesterolemia was accompanied by accumulation of biologically active substances and reduced indices of degranulation and granulolisis, one course of immunomodulator may lead to normalization of the relative rates, prolonged administration - to strengthen the processe of granulolisis and accumulation of biologically active substances in the extracellular medium.