DIED NEWBORN''S LUNG TISSUE MORPHOLOGICAL CHANGES UNDER DIAPHRAGMATIC PSEUDOHERNIA DIAGNOSED
Objective. To identify the lung tissue morphological changes in newborns with congenital diaphragmatic pseudohernia after fatal outcomes. Materials and methods. Archive of autopsy materials of 10 newborns having died in the neonatal period served the material for the study. Results. The late (after 20 weeks of pregnancy) prenatal diagnosis of congenital malformation - the diaphragmatic pseudohernia - was noticed in each case. Hypoplasia of the lung was detected both - on the defect side and on the contralateral side in all the cases. Conclusion. Multiple malformations (6 cases) and significant fetal communications presence (10 cases) determined the clinical condition severity and the disease future outcome. The study identified clinically relevant morphological and functional changes in the lungs in case of congenital diaphragmatic pseudohernia and testified the lung tissue and blood vessels immaturity and hypoplasia as well as the postnatal respiratory damages associated with the mechanical ventilation.