Combined therapy with diuretic and angiotensin-converting enzyme inhibitor in a new strategy for the treatment of hypertension
In 110 patients with arterial hypertension (AH) II st., the effect of combination therapy with an inhibitor of angiotensin-converting enzyme perindopril and thiazide-like diuretic indapamide was studied in the form of a fixed combination of Co-Prenessa (KRKA, Slovenia) for clinical status, office blood pressure and structural and functional state of the heart in the process of 6-month therapy. It is shown that combined therapy leads to achievement of the target level of systolic blood pressure in 72% of patients and diastolic in 78%, accompanied by an improvement in the clinical state, a positive restructuring of the structural and functional state of the left ventricular myocardium.