SUPEREARLY SURFACTANT THERAPY INFLUENCE ON NEONATAL MORTALITY
Several practices of surfactant therapy are used in modern neonatology such as early replacement therapy and late therapy after gas exchange and acid-base balance stabilization. Preterm neonates' mortality rates during the periods of late and early surfactant replacement therapy strategies have been investigated. In 2007 the late surfactant therapy practice was selected as preferable. 2008 was the year of discussion and unification of strategies. As a result early surfactant replacement strategy was chosen by all physicians. In 2009 all preterm born neonates were administered Curosurf immediately after birth with further support by CPAP or IMV in cases when CPAP was not enough to maintain adequate gas exchange. In 2007 23 preterm newborns out of 656 live born infants died. In 2009 515 preterm neonates have been admitted to NICU of whom only 13 died. Superearly surfactant therapy appeared to be more beneficial and allowed to reduce mortality of preterm neonates by more than 30%