Structure of neuropsycological defect of disseminated sclerosis patients
The authors have studied the structure of neuropsycological defect of 86 patients with various types of the course of cerebrospinal disseminated sclerosis. Regardless of the course type, the core of psychopathologic disorders is composed of triad of symptoms, among which are cognitive deficiency, emotional-volitional disorders, and vegetative disfunctions. The cognitive deficiency comes from disorder of motor control. The emotional-volitional disorders are characterized by forming of anxiodepressive states, while the vegetative disfunctions cover the utter variety and lability of manifestations. The degree of manifestations of psychopathologic defect depends on the disease state and location of demyeliniation focuses. The destruction of ties in the systems supporting control over regulation of mental activity, which are suprasegmental vegetative apparatus, plays a key role in the development of psychological deficiency.