ETIOPATHOGENETIC ASPECTS OF METEOROLOGICAL CHEILITIS IN THE EXTREME NORTH
Traumatization of the lips by adverse meteorological conditions during the cold season predisposes to the development of meteorological cheilitis, which is often ignored by doctors. The diagnosis can be complicated by the addition of an infectious agent against the background of a chronic violation of the integrity of the tissues, and with a long course it can turn into obligate forms ofprecancerous diseases ofthe lips. In the development ofmeteorological cheilitis in residents of the Far North, a special role is played by "polar" metabolism and a weakened antioxidant defense of the body, which is the most important link in the pathogenetic mechanism for the development of meteorological cheilitis in the population. The purpose of this study is to improve the system of diagnosis and treatment of meteorological cheilitis, taking into account etiopathogenetic features. Material and methods. The study included patients with a confirmed diagnosis of meteorological cheilitis without a burdened anamnesis. After collecting an anamnesis, examination, general and local therapy was prescribed. Before and after treatment, a biochemical study of the content of vitamins A, E, D in the blood serum was carried out. Results and discussion. An analysis of the content of vitamin D before treatment indicates a low level of vitamin D in more than 50% of the subjects, the results of the remaining patients are in the range of the lower limit of the reference values. The content of vitamins A and E in the serum of venous blood is in the acceptable range. 2 months after treatment, the content of vitamin D in the blood serum of all patients rose to normal levels. Conclusions. Complex local and general therapy led to the neutralization of the clinical manifestations of meteorological cheilitis in 100% ofpatients. A scheme for the prevention of meteorological cheilitis in residents in adverse climatic conditions has been developed.