LEUKOCYTE-PLATELET AGGREGATION, HEMOLYSATE-AGGREGATION TEST, PARAMETERS OF ERYTHROCYTES AS A METHOD FOR THE DIAGNOSIS OF DISORDERS OF PRIMARY HAEMOSTASIS AND BLEEDING RISK IN PATIENTS WITH ARTERIAL HYPERTENSION
A method for the diagnosis of disorders of primary haemostasis and bleeding risk in patients with hypertension based on the analysis of parameters of hemostasis, red blood cells was presented. We identified the most significant in terms of diagnostic indicators: hemolysate-aggregation test in different dilutions (for GAT 102 – AUC 0,989, for GAT 106 – AUC 0,952), leukocyte-platelet aggregation (AUC 0,823) and the polarizability of erythrocytes in the frequency 106Гц (AUC 0,999). There were discriminatory values of these parameters for the different risk of bleeding in patients with arterial hypertension. We determined sensitivity of 90.9 % and specificity of 100 % when using the set of parameters of hemostasis, red blood cells to diagnose disorders of primary hemostasis, bleeding.