Intracranial haemorrhage in a children suffering from heamofilia
Haemophilia is a hereditary X-linked desease manifested in coagulatory hemostasis disorder. Haemophilia A is a recessive mutation in X-chromo- some which results in the absence or malfunction of blood clotting factor VIII. Its frequency from 1:5000 to 1:10,000 of born boys. Haemophilia B is caused by the factor IX deficiency (recessive mutation in X-chromosome), with an incidence from 1:25,000 to 1:30,000 of born boys. Frequency of occurrence hemorrhagic stroke in children is 0.7-5.1 (average - 2.9) per 100,000. Reported intracranial hemorrhages (ICH) boys with haemophilia are rare, however, according to foreign authors encountered in 1.7-11.7 % of patients that with appropriate recalcu- lation was 290-2142:100,000 per year. Thus, the risk of ICH patients with hemophilia in 56-420 times higher than the general population. The median age of children with ICH ranges from 5.9 months to 8 years. Operational tactics not developed.