THE INFLUENCE INTRASPLENIC TRANSPLANTATION OF THE PANCREATICISLETS ON THE ENDOCRINE TISSUE OF PANCREAS IN RABBITS WITHEXPERIMENTAL DIADETES
Indices of carbohydrate metabolism and histological structure endocrine tissue of the pancreas inrabbits with experimental diabetes after intrasplenic allo- and xenotransplantation of pancreatic isletsof neonatal animals has been studied. It was found that intrasplenic transplantation of islets restoresand maintains the long-term within the physiological norm of carb ohydrate metabolism withouthypoglycemic episodes. Intrasplenic transplantation pancreatic islets activates of the autoregenerationin endocrine pancreatic tissue of recipient animals, leading to the pool restoration of insulin-producingβ-cells.