Diagnostics of non-motor disturbance in Parkinson’s disease
The aim of the research. Identification of formation and course patterns of non-motor disturbances in Parkinson’s disease for the selection of the most appropriate method of correcting and slowing the disease progression. Material and methods. A non-motor fluctuation scale in Parkinson’s disease was used, a correlation analysis was performed to evaluate the relationship between severity and frequency of dysuric non-motor symptoms such as: increased urination, urgencies, nocturia, and variance analysis to detect statistically significant difference between different study groups, depending on the disease duration. Results. It was found that lengthening of Parkinson’s disease duration increase the severity and frequency of dysuric non-motor manifestations (increased frequency of urination, urgencies, nocturia); according to the data obtained by non-motor fluctuations scale, there is a direct correlation between the results of severity and the results of non-motor manifestations frequency; on the basis of the conducted dispersion analysis, statistically significant effect of the disease duration on the manifestation of severity and frequency of dysuric disorders in patients with Parkinsons disease was noted. Conclusion. It is necessary to take non-motor fluctuations into account in the treatment of patients with Parkinson’s disease, as well as actively to interrogate them for the presence of these complaints. There is a large number of methods for their diagnosis, but these are subjective and time-taking evaluation methods, so the issue of creating a new quicker and objective ways of qualitative non-motor disturbances’ evaluation remains open. Qualitative and timely treatment of non-motor symptoms will slow the progression of the disease, reduce disability and improve the quality of life of patients with Parkinson’s disease.