ASSESSMENT OF THE STATE OF THE MICROBIAL FLORA OF THE OROPHARYNX AND THE LEVEL OF ENDOTOXEMIA IN PATIENTS WITH HIV INFECTION
The composition of the microflora of the oropharyngeal mucosa and biochemical markers of endotoxemia were evaluated with the determination of the content of LPS-P in the blood of 100 HIV-positive patients receiving antiretroviral therapy. Intensive colonization of the oropharyngeal mucosa by conditionally pathogenic microbial flora in high quantitative titers and more than 14-fold excess of the LPS-P level was revealed. The addition of sodium aminodihydrophthalazinedione («Galavit») to therapy for 4 weeks provided a significant decrease in the concentration of LPS-P in the blood and normalization of the microbial composition of the oropharyngeal mucosa in most patients with HIV.