Features of the course of oral mucositis in patients with anxiety on the background of squamous cell carcinoma of the oral mucosa
The increase in the prevalence of oncological diseases of the oral cavity, maxillofacial region and neck causes a significant increase in the use of radiation and chemotherapy. These types of therapy can significantly prolong the life of the patient. However, radiation therapy causes the development of radiation mucosits of the oral mucosa of varying severity. The development of radiation mucosits of the oral cavity is based on damage to the cells of the epithelium of the oral cavity by ionizing radiation, which, thereby, sharply reduces the protective function, stopping the production of hyaluronic acid. This leads to the appearance of micro cracks, the development of inflammation and the appearance of sharply painful ulcers in the oral cavity. In this state, eating becomes impossible. This circumstance requires the suspension of radiation therapy, which has an extremely negative impact on the results of treatment. Therefore, predicting the degree of mucosits according to the type of psychological reaction seems to be timely and relevant and makes it possible to prevent it. This study made it possible to predict the severity of oral mucosits. Thus, psychological reactions of an alarming orientation in patients with oral mucosits against the background of squamous cell carcinoma of the oral mucosa cause the development of grade 3 mucosits in 75% of cases, grade 4 in 25% of cases.