DESYNCHRONIZING EFFECTS OF MEDICATIONS USED FOR SEDATION IN CASES OF COMPLICATED ALCOHOL WITHDRAWAL SYNDROME
The study included 71 patients with complicated alcohol withdrawal syndrome. The authors analyze the data of the monitoring of blood pressure, heart rate, respiration, saturation of blood with oxygen, body temperature and hourly urine output which were registered at the stage when withdrawal symptoms were aggravated by the psychic ones. Therewith, different schemes of medical sedation were applied. The desynchronizing effect of medical sedative therapy manifests itself in the collapse of the circadian structure of biological rhythms of the parameters of life-supporting systems of the body, intersystem discoordination and pathological drift of acrophases.