RESULTS OF NON-DRUG CORRECTION OF CLINICAL-METABOLIC STATUS OF ADOLESCENT BOYS BEFORE THEY JOIN THE ARMY WITH METABOLIC SYNDROME
The purpose of this study was to identify the metabolic syndrome in adolescent boys before they join the army in the Donetsk region and its nondrug correction.Material and methods. Based on the results of a comprehensive survey of 547 adolescent boys aged 15-16 years, the mosaic metabolic syndrome was detected in 45 (23.4%) persons.Adolescents with the metabolic syndrome had an increased body mass index, waist measurement, overweight, and blood pressure ≥ 130/85 mm Hg. In adolescents, high values of glucose in blood serum on an empty stomach were revealed. The average level of triglycerides corresponded to physiological parameters; however, it was signiﬁ cantly higher than in the control group. Low-density lipoproteins in boys with the metabolic syndrome were signiﬁ cantly higher (2.3±0.2 mmol/L, p <0.001) than in the control group (1.6±0.2 mmol/L), and high-density lipoproteins were lower, however, not reaching the measure of conﬁ dence.As the main directions of the therapeutic effect, the following were chosen: diet therapy, lifestyle modiﬁ cation with normalization of motion activity.Consultations during the ﬁ rst month were held once a week, then twice a month for 6 months.Results and discussion. Assessment of changes in eating behavior of adolescent boys with the metabolic syndrome after 6 months showed, that the majority of patients - 43 (95.6%) implemented recommendations for nutritional management, reducing the total caloric intake and fat intake, and organizing the diet. There were no complaints of hunger during the day, 42 (93.3%) of the children considered it possible to adhere to the same diet principles as long as they wished.The clinical effect (weight loss) in 6 months was noted in 38 (84.4%) adolescents. Target level of weight loss - by 5-10% in 6 months reached 32 (71.7%) of the boys, 12 (26.7%) of the examined stabilized body weight. Total cholesterol decreased on the average by 11.6%, mainly due to low-density lipoproteins. The Atherogenic Index decreased and did not differ signiﬁ cantly from the control group. Glycemic levels on an empty stomach in 6 months from the start of therapy remained within normal range and did not differ from the control group.In adolescent boys with the metabolic syndrome, the target values of systolic blood pressure (<90 centile) were achieved after 6 months of therapy. The level of diastolic blood pressure was maintained at the same values.Conclusions. Thus, among conditionally healthy adolescent boys, 15-17 years of age, disorders, typical of the metabolic syndrome were detected in 8.2% of the examined. Adolescents were overweight, increased body mass index and waist measurement, the atherogenic orientation of the Lipemic index changes was marked.A decrease in body weight, indexes of waist measurement and hip width, decrease of total cholesterol level, mainly due to low-density lipoproteins, the Atherogenic Index, normalization of blood pressure value was established in the course of nondrug treatment.