DEVELOPMENT OF THE TECHNIQUE OF QUALITY CONTROL N-GEKSADETSILTRIFENILFOSFONIYA BROMIDE (C16), POSSESSING ANTIBACTERIAL AND FUNGICIDE ACTION
The C16 Biologically Active Agent (BAA) is synthesized on chair of high-molecular and elementoorganichesky connections of Chemical institute of A.M. Butlerova of the Kazan (Volga) federal university also represents bromide from the chemical point of view of N-geksa-detsiltrifenilfosfoniya. Microbiological and the BAV S16 pharmacological properties are studied in the Kazan state medical academy on chair of microbiology and in the Kazan state academy of veterinary medicine on chair of veterinary surgery. Antibacterial and fungicide pharmacological effects are revealed. The main physical and chemical properties of new BAV S16 of a class of quarternary salts a fosfoniya with antibacterial and fungicide activity are studied, and on their basis the technique of definition of its quantitative contents is developed. UF-spektor of absorption of N-geksadetsiltrifenilfosfoniya of bromide is studied, characteristic strips of the main functional groups are allocated. Optimum conditions of spektrofotometrichesky determination of N-geksadetsiltrifenil-fosfoniya of bromide are found in a substance. The technique of the quantitative analysis of a substance of N-geksa-detsiltrifenilfosfoniya of bromide is developed by UF-spektrofotometriya’s method, optimum conditions of carrying out quantitative definition are defined, is established that concentration pay off on a specific indicator of absorption, on solution of a standard sample or on a calibration curve. The smallest relative error of result of definition at calculation of the maintenance of C16 for a standard sample with confidential probability of 95 % makes ±0,36 %.