Dynamics of the content of B-EAC-lymphocytes in bursa and Harderian gland in geese during the therapy of mixed nematode invasion
The effects of the therapy of combined invasion of Amidostomum and Ganguleterakis nematodes in Hungarian geese by anti-tapeworm drug Alben combined or not combined with probiotic Vetom on the percentages of B-EAC-lymphocytes in bursa and Harderian gland were studied on four treatments of 28-day goslings (8 birds per treatment). Birds of treatments 1-3 were invaded; treatment 4 was not invaded (healthy control). No therapy was applied to treatment 1 (invaded control). In treatments 2 and 3 Alben was administered (1 pill per 35 kg of live bodyweight once a day during 2 days); this therapy for treatment 3 was augmented by administration of Vetom (50 mg/1 kg of live bodyweight twice a day during 12 days). It was found that the percentages of B-EAC-lymphocytes in bursa and Harderian gland at 21th and 56th days of the experiment in treatments 2 and 3 increased in compare to the respective initial levels which were significantly lower in compare to the initial levels in non-invaded treatment 4. In treatment 2 these parameters were higher in compare to treatment 1 though still lower in compare to treatment 4, evidencing that the deworming drug slowed the development of pathological alterations in the immune organs though did not restore the immune status to the level of healthy birds. In treatment 3 these parameters were close to those in treatment 4 evidencing that the probiotic effectively enhanced the restoration of the specific resistibility in the dewormed goslings.