EEG COHERENCE CHARACTERISTICS IN DEPRESSIVE CONDITIONS WITH DIFFERENT PREVALENT AFFECTS
The author makes an attempt to describe the characteristics of cortical integration in depressive patients, with regard for the prevalent affect. Material: 202 patients (83 male and 119 female) with moderate recurrent depressive disorder (F33.11 according to the ICD-10; the HDRS score: 19-20), aged 19 to 45 years. Among the participants, 92 patients had prevalent anxious affect, 69 had prevalent sad affect and 41 had prevalent apathetic affect. The control group consisted of 52 healthy persons. The author shows with the help of EEG coherence analysis that the prevalent affect was associated with tessellated cortical interactions and formation of various patterns of interhemispheric asymmetry. Thus, with general lower coherence as a background, anxious depression was associated with relative tension of anterior right-hemisphere and posterior left-hemisphere integrative processes, sad depression - with anterior and medium temporal, frontal and parietal left-hemisphere ones, and apathetic depression developed as a result of exhaustion of both right- and left-hemisphere integrative mechanisms.