Bacterial 1,2-Dehydrogenation of 17-a-Methyltestosterone in the Presence of Synthetic Polymers
The influence of synthetic polymers (polyvinyl caprolactam, polyvinyl pyrrolydon and polyvinyl alcohol) of various molecular masses on the efficiency of microbiological 1,2-dehydrogenation of 17-a-methyltestosterone has been investigated. The best results (the yield of methandrostenolone 70% at a substrate concentration of 4 g/l) were obtained using high-molecular polyvinyl caprolactam and polyvinyl pyrrolydon, used in concentrations 1-3,5%.