THEORETICAL BACKGROUND AND REAL RESULTS: A DATA REVIEW ON VACCINE PREVENTION OF PNEUMOCOCCAL INFECTION IN THE WORLD
The article presents the review aimed at summarizing the opinions on the epidemiology of pneumococcal infection and the most effective measures for its prevention. The review combines the results of the trials conducted by Russian and international groups who analysed vaccine prophylaxis of pneumococcal infection. In the previous review on the most important indicators of the effectiveness of vaccination against pneumococcal infection, the main approaches to the assessment of the effectiveness of vaccination against pneumococcal infection were identified, and the academic data on the global experience of pneumococcal conjugate vaccination was systematized. This review results in cumulation of evidence for the efficacy and impact of pneumococcal conjugate vaccines on the key «end points» of the epidemiological process of pneumococcal infection.