INFLUENCE OF CARDIOVASCULAR AUTONOMIC NEUROPATHY ON THE PREVALENCE OF CORONARY HEART DISEASE
Cardiovascular autonomic neuropathy (CAN) is a very common complication of diabetes, has a great influence on the development of cardiovascular disease and mortality in patients with diabetes. Relationship of CAN and coronary heart disease (CHD) is the subject of numerous studies, most of them show an association of CAN and silent myocardial ischemia. In our study, the aim was to identify the relationship between CAN and prevalence of various forms of CHD. In accordance with the inclusion and exclusion criteria, the study included 83 patients with type 1 and type 2. Study groups were matched for age and sex (p> 0,05) All patients underwent a comprehensive examination, including an analysis of heart rate variability by computer rhythmocardiography. The study revealed that the duration of diabetes in patients with CAN was significantly higher than in the group without disorders of the autonomic cardiovascular regulation. (P <0,01) Waist circumference in payions with CAN was greater than in group without CAN. (P <0,05). Incidence and severity of hypertension was significantly higher in patients with CAN. (P <0,01). Exertional angina was more common and more severe in patients with CAN than in the group without CAN. (P <0,05) In patients with CAN chronic heart failure developed more often and resulted in a greater limitation of physical activity(P <0, 01).