AFFECTIVE PROFILE OF PATIENTS WITH DIABETIC ENCEPHALOPATHY
Background: disorders of diabetes mellitus (DM) are one of the most common and often leading to irreversible changes in the central nervous system. The dominant position is occupied by diabetic encephalopathy (DiabEP) with the development of neuropsychological disorders.Aims: to identify affective disorders in patients with DM type I and II, depending on the presence of DiabEP and estimate the degree of severity of their development.Materials and methods. Neuropsychological examination was performed in 275 patients with diagnosed DM (I- 28,4%, II- 71,6%). All patients were divided into 2 groups: the main group (GrO) - 161 (58,5%) people with DiabEP and DM (I - 36%, II - 64%) and control (GrC) - 114 (41,5%) patients without DiabEP in DM (I - 41.2%, I - 58.8%).Results. DiabEP II stage (63.8%) and III stage (36.2%) were diagnosed in GrO with DM I and DiabEP II stage (69.9%) and DiabEP III stage (30.1%) were diagnosed in GrC with DM II. In the group of patients with DiabEP and DM I, anxious (27.6%) and anxiety-depressive (13.8%) disorders. In GrO, patients with DM II and DiabEP were more likely to experience anxiety (34%) and less commonly anxiety-depressive (15.5%) syndromes. In the GrC anxiety-depressive (36.2%) and depressive (44.8%) disorders prevailed with DM II. In this case, there were statistically signiﬁ cant differences in the syndromes of affective disorders between types of DM. It was established that with DM, anxiety, anxiety - depressive syndromes were statistically predominant in DM I and II, as well as depressive and anxious in GrC. At the same time, in the GrO with DiabEP II with DM I, small depressive episodes (DE) (48.6%) with subdepression (56.8%) prevailed and with DiabEP III, moderate DE (57.1%) with a moderate level of depression (52.4%). In DM II and DiabEP II, DE (48.6%) was more often absent in the presence of subdepression (43.1%), and with DiabEP III there were moderate DE (38.7%) with severe depression (35.5%). In the GrC, with DM I, small DE prevailed (57.4%) with a moderate level of depression (36.2%), with DM II in 53.7% of cases there were no DE. Conclusions. Changes of affective proﬁ le in DM in both groups reliably show us that emotional and personality disorders occurred in all patients with DiabEP (GrO), while in the group without DiabEP (GrC) there were 16.7 ± 3.5% of cases