Radioendovascular Interventions in the Treatment of Unresectable Liver Metastasis in the Noncolorectal Cancer Patients
An efficacy of the radioendovascular management in 182 unresectable liver metastasis of the noncolorectal cancer patients is studied. Courses of 5-FU, doxorubicin, taxoter, mitomycin C, carboplatin and gemcirabin chemoinfusion into the hepatic artery were provided in 66 patients. Oil chemoembolization of the hepatic artery by means of the same cytostatics and oil contrast media was carried out in 71 patients. Combination of the modalities was applied in 45 patients. Mean life duration of the breast cancer metastasis patients after chemotherapy through the hepatic artery came to 18.6 ± 6.7 months, one year, two year and three year survival came to 42, 25 and 17% respectively. Mean life duration in these category patients composed 18.8 ± 2.2 months, one year, two year and three year survival came 81, 57 и 14% respectively. Mean life duration in the liver metastasis patients after combined treatment came to 20.7 ± 5.4 months. Good results were obtained also in the gastric cancer liver metastasis patients group. Mean life duration in the group of nonepithelial tumors composed 25.6 months, in ovarial cancer metastasis - 19 months, renal cancer metastasis - 11.7 months and pancreatic cancer metastasis - 12.2 months. It was established, that in cases of unknown primary location adenocarcinoma metastasis, and also lung and uterus cancer and melanoma metastasis mean life duration does not exceed 10 months. Thus, interventional radiology tools are effective in the treatment several morphological forms of noncolorectal liver metastasis.