AUTISM MODELS AND ASSESSMENT TECHNIQUESFOR AUTISTIC-LIKE BEHAVIOR IN ANIMALS
Autism spectrum disorder (ASD), including autism, are presented by a wide range of states, and are associated with deficit of social communications, limited interests and repetitive behavior. Development of translational medicine and personalized approach in the treatment of ASD join efforts of clinical and basic science. Research direction is shifted towards studying molecular and genetic pathways of developmental disorders, to search new molecule markers for targeted therapy of these states. It is impossible without using of ASD animal models in particular in rodents. This review discusses a key genetic and pharmacological ASD models and most significant behavioral tests for assessment of social deficiency, repetitive and autistic-like features in experimental animals.