Mono and combined therapy of wounds in rabbits by platelets autological plasma
This article contains information about the influence of platelet autoplasma on the healing of experimental wounds in rabbits. Wounds were a scalpel on the dorsal side of the body. Rabbits were divided into 3 groups of 5 animals: the first - control (treatment: ointment "Levomekol"), the second - experimental (treatment: ointment "Levomekol" + platelet autoplasma), the third - an experimental (treatment: Only platelet autoplasma). Platelet autoplasma obtained by centrifugation in special tubes "Plazmolifting tm" (Russia) with the separation gel. Platelets plasma remained above the gel, and other blood cells beneath. Platelet autoplasma administered immediately after preparation at the bottom of the wound. According to the study found that treatment with platelet autoplasma effectively and in mono, and adjuvant therapy, but the latter has the most pronounced effect. When administered to autoplasma platelet destruction takes place release of biologically active substances - a variety of growth factors from platelet α-granules and mediators of ß-granules, which has anti-inflammatory effect and contributes to the activation of regenerative processes in tissues. Furthermore, Coats, remote field operations in preparing the rabbits in the experimental group recovered rapidly and was more abundant in comparison to the control group. The use of platelet autoplasma is an effective treatment of wounds in animals, because it is safe, does not cause allergic and autoimmune reactions, reduces the time of the use of antibiotics.