THE MAIN PROBLEMS OF PREGNANCY AFTER ART
The analysis of the main problems of pregnancy after assisted reproductive technology (ART). It is emphasized that infertility, like subfertility, are independent risk factors for the induction of obstetric complications and adverse perinatal outcomes, even outside of ART. The health of the couple before conception makes a significant negative contribution to the burden of the formation of obstetric pathology during pregnancy. It has been established that age and high estrogen levels are independent predictors of hypercoagulation. It is proved that genetic polymorphism for thrombophilia does not affect the outcome of pregnancy after ART. Testing for APS is more likely to show positive results among women with infertility, but no correlation is found between APS and outcome after ART. ART was associated with an increased risk of premature detachment of a normally located placenta, placenta previa, rotation of the placenta, vasa previa. The main obstetric complications of the mother, fetus and newborn are summarized. A significant role of ART in the occurrence of such complications of pregnancy as placental insufficiency, preeclampsia, and multiple pregnancy has been shown. There was a high risk of the formation of a small-sized fetus at the time of gestation, prematurity, and massive bleeding. It was emphasized that treatment with the use of ART may predispose subsequent offspring to an increased risk of chronic diseases affecting the quality and longevity.