TRANSCANALICULAR IRRIGATION WITH MITOMYCIN C DURING REPEATED ENDOSCOPIC ENDONASAL DACRYOCYSTORHINOSTOMY
Because of ability of Mitomycin C to inhibit proliferation of fibroblasts and vascularization in the area of the surgical wound, it is used in dacryosurgery to prevent scarring of the dacryostoma. We analyzed the effectiveness of Mitomycin C irrigation at the final stage of endoscopic endonasal dacryocystorhinostomy. The study included 10 patients with recurrence of epiphora after endoscopic endonasal dacryocystorhinostomy. We repeated endoscopic endonasal dacryocystorhinostomy with intraoperative transcanalicular irrigation with 1 ml. of Mitomycin C solution in concentration of 0.2 mg/ml. To prevent damage of the cornea, adhesive viscoelastic was applied to its surface. The result of our study: in 9 patients there was a positive outcome, recurrence in one patient, indicating the efficiency of intraoperative irrigation of the tear duct with mitomycin C in patients with recurrence of epiphora after endoscopic endonasal dacryocystorhinostomy.