PROBLEMS OF USING BRAIN DEFORMATION MODELS FOR PREOPERATIVE PLANNING OF GLIAL TUMOR TREATMENT
Brain is a composite material with different properties of structural components and is characterized by the complexity of its description as a physical object, as well as the prediction of deformations of brain structures. This fact complicates the preoperative preparation for brain tumor resection and is one of the main factors of recurrence. Preoperative MRI images are used for surgical planning. However, the topography of the brain structures and tumor identified in the preoperative MRI images becomes irrelevant during surgery when the brain is opened, because there is a problem of inconsistency between the location of the tumor process in the preoperative images and during the surgery. Deformation processes in the brain primarily cause this discrepancy. The deformation process and, as a consequence, the change of dislocation of the brain structures during surgery is caused by the pressure difference: when the skull is opened, the brain pressure changes from intracranial to atmospheric pressure, as it is no longer confined to the rigid skull. In the present work, various applied approaches to modeling of the brain behavior and deformation of its structures are considered and analyzed in accordance with the formulated criteria. The relevance and prospects of developments in this direction are established.