Extracorporeal haemocorrection in optimization of treatment of chronic urogenital infection in women
To study the effectiveness of treatment of female patients with chronic urogenital infection by the method of extracorporeal antibiotic and immune therapy. Patients and methods. We examined 120 women with chronic urogenital infection (UGI). Two groups of patients were singled out: group 1 (basic) included patients (n = 80), who underwent treatment employing the method of extracorporeal antibiotic and immune therapy; group 2 (control, n = 40) - patients treated by traditional methods with the use of modern antibacterial drugs. The diagnosis of UGI was verified by methods of polymerase chain reaction (PCR) and bacteriological analysis of discharge from the cervical canal, vagina and urethra. Results. The results of treatment were assessed after 2 weeks, one and two months. In the basic group, 2 weeks afterwards a faster regression of clinical manifestations of disease and improvement of general wellbeing were noted; in the control group, symptoms of disease persisted in more than 50% of women. After month, patients of the basic group had no complaint, whereas in the control group symptoms of disease remained in 30% of patients. After 2 months, patients of the basic group had no complaints but in 1.25% leukocytosis persisted in a smear and the growth of Trichomonas was noted. In group 2, discharge continued in 7.5%, positive inoculation for Trichomonas were in 5.0% of patients. Conclusions. The study demonstrated the clinical effectiveness of the method of extracorporeal antibiotic and immune therapy in treatment of chronic UGI as compared with traditional methods, contributed to a faster eradication of the causative agent, coped with inflammatory process.