Clinical-and-pathological and molecular factors of portal cholangiocarcinoma prognosis
An analysis of clinical-and-pathological and molecular risk factors in 36 patients with portal cholangiocarcinoma (Klatskin tumor). It is shown that the degree of differentiation of tumor cells (p=0,0137) and distribution of tumor tissue in the liver ducts SI (hepatic SI resection) (p=0011), are significantly affecting the prognosis of the disease. Between the expression of the molecular marker N-cadherin and overall survival set moderate correlation (p=0,032), between other markers - weak (p>0,05), but by the last possible final verification of the type of tumor cells.