Development of Multiplex Genotyping Method of Polymorphic Markers of Genes Assoсiated with Cognitive Abilities
Developed method of multiplex genotyping of polymorphic markers of genes associated with cognitive abilities and neuropsychiatric diseases is based on multilocus PCR and MALDI-TOF mass spectrometry of DNA molecules. The frequencies of 32 single-nucleotide markers localized in 24 genes were analyzed in a samples of elderly people from the Russian population of Tomsk. The data obtained are compared with data for populations from the "1000 genomes" project.