THE USE OF INDIVIDUAL LIPID FRACTIONS SAPROPEL FOR CORRECTION OF THE LIVER EXCRETORY FUNCTIONS OF RATS WITH TOXIC CHEMICAL HEPATITIS
Relevance due to lack of knowledge of the biological effects lipidorhistory fraction of peloids, while well known for the curative properties of the water-soluble components of these compounds. The aim of this work was to investigate the effects of some fractions of lipids sapropel for the correction of the excretory functions of the liver of rats with toxic chemical hepatitis. The experiments were carried out on 50 white rats male Wistar rats. On the model of toxic and chemical hepatitis studied the effects of applications of the solutions of the total lipid extract and polar fractions of lipids sapropel in the process of biliary excretion. Determined the content of total bilirubin and cholesterol, bile acids. It is shown that the application of the total lipid extract of sapropel have a regenerating effect on the process of bile secretion, formation of bilirubin, synthesis of bile acids. The effects of the polar fraction of lipids sapropel were less pronounced. Therefore, the lipid components of sapropel can be used for correction of the excretory functions of the liver.