Comparative assessment of effectiveness and safety of inhalational and intravenous anesthesia at coronary artery bypass in patients of an elderly and old age
Aim of research. The work deals with an influence of anesthetics (sevoflurane and propofol) that are used at anesthetic management of patients of elderly and old age with ischemic heart disease at coronary artery bypass on postoperative dynamics of cardiospecific enzymes (MB-CPK and Ti I).Materials and methods. The research included 63 patients of elderly and old age with ischemic heart disease who underwent coronary artery bypass in conditions of artificial blood circulation on the base of SI “Heart institute of MPH of Ukraine”.The results of research. As the result of research there was revealed that in 12 hours after the end of operation there was observed the growth of MB-CPC values in both groups. But in the group where was used propofol this enzyme indices increased in the mean by 45,9±3,2 % compared to initial value that was 1,4 time more that analogous indices in group where was used sevoflurane.Тi І values in group with sevoflurane use were in the mean by 29,6±2,7 % less than the correspondent values of this enzyme in the group of patients operated in conditions of propofol anesthesia.Conclusions. So at sevoflurane anesthesia there was detected the more significant cardioprotective effect compared with an intravenous propofol anesthesia that was proved by the dynamics of cardiospecific enzymes in early postoperative period