Systemic thrombolysis in patients with ischemic stroke in Sverdlovsk region. Reperfusion "delights" and hemorrhagic "disasters"
Widespread launching of systemic thrombolysis in patients with ischemic stroke to clinical practice presumes an extensive investigation of characteristics, that influence an outcome. Our paper includes the results of systemic thrombolysis in ischemis stroke patients admitted to stroke centers of Sverdlovsk Region in 2009-2013. Hemorrhagic transformation is one of the most feared factors that affects the outcome of systemic thrombolysis and functional recovery of patients with ischemic stroke. We have analyzed results of systemic thrombolysis in survived patients depending on hemorrhagic transformation of ischemic focus. Logistic regression analysis revealed the most significant factors that anticipated hemorrhagic transformation of infarct, that included diastolic blood pressure at admission and level of independency of living at admission.