BONE REMODELING PROCESSES AT THE STAGES OF CORRECTION OF EXPERIMENTALLY INDUCED OSTEOPOROSIS
The experimental work analyzed the evaluation of the pharmacological efficacy of 3 experimental samples of the preparation, created on the basis of salts of succinic acid in comparison with the comparison drug. On the experimental model of osteoporosis, according to the application of atomic absorption spectroscopy and flame photometry of the femur, the high efficiency of the new drug in the correction of induced pathology has been proved. The data obtained indicate that when using acid salts of the natural conformer of succinic acid, it is possible to achieve sufficient saturation of bone tissue with calcium without overloading the body with excess calcium. The developed and studied anti-osteoporotic agent can contribute to more effective treatment and prevention of age-related and postmenopausal osteoporosis. With the chosen treatment method, the risk of disabling fractures is reduced, and the financial costs of prevention and treatment and maintenance of the life of patients suffering from postmenopausal osteoporosis are reduced accordingly.