The Level of MMP-9 in Saliva in Patients with a Cyst of the Maxillary Sinus
Introduction. The causes of development of the cyst of the maxillary sinus are still not fully understood. One of the causes of the formation of a cyst of the maxillary sinus is chronic inflammation in the upper jaw, in particular, chronic periodontitis. Chronic inflammation in rhinosinusitis is known to be accompanied by tissue remodeling. Purpose. Determine the content of MMP-9 in saliva in the pre- and postoperative periods in patients with a maxillary sinus cyst and compare the results obtained with data on the presence of an inflammatory process in the maxilla bone around the roots of the upper teeth.Materials and methods. The data obtained during the examination of 125 patients were analyzed. Patients were divided into three clinical groups. The first group is a cyst of the maxillary sinus and chronic periodontitis. The second group is a cyst of the maxillary sinus without a pathology of the dentition. The third - the nasal septum deviation, vasomotor rhinitis neurovegetative form. Results. An increase in the content of the MMP-9 enzyme was detected only in patients of the 1st clinical group. No statistically significant difference between the indicators before surgery (average 1219 (±328) ng/ml) and after surgery (1110 (±283) ng/ml) was found. In patients of the 2nd and 3rd groups in the study before surgery, and in the postoperative period, no statistically significant differences were found between the content of the enzyme MMP-9. In patients of the 2nd clinical group, before the operation, the average enzyme content was 495 (±128) ng/ml, and in the postoperative period - 497 (±118) ng/ml. In patients of the 3rd group, prior to surgery, the content of MMP-9 was 437 (±118) ng/ml, and in the postoperative period 424 (±148) ng/ml.