Glia at the Tripartite Neuromuscular Junction
In this review, perisynaptic Schwann cells (PSCs) are considered as an active component of a tripartite synapse. The possibility of synaptic transmission modulation by PSCs is shown. The mechanisms by which PSCs are not only able to detect synaptic activity, but also can modify it, are described. In addition, modification PSCs in pathologies of the peripheral nervous system are described and the possibility of using PSC as potential targets for therapeutic treatment is discussed.