Cytomorphological Changes in Blood and Mesonephros of Goldfish Infectedwith Ligula (Digramma) interrupta (Cestoda: Pseudophyllidea)
The cytomorphological composition of the blood and mesonephros of goldfish infected with Ligula interrupta was studied in the conditions of the native areal. A decrease in the blood of the total number of leukocytes and neutrophils at all stages of development, a disruption of the proliferation and differentiation of lymphoid, pseudo-eosinophilic and pseudo-basophilic elements in the studied organs was established. Neutrophilic mesonephros infiltration with mild-differentiation forms was observed. It has been shown that in this parasitic system, partner relations are came down to the launch with L. interrupta of mechanisms that regulate the host’s immune response by inhibiting the acute inflammatory response and the development of mild chronic inflammation. Activation specific B-cell of immunity response was accompanied by processes of cellular degeneration and immunosuppression of factors that are actively involved in cytotoxic reactions.