Marble bone disease
Marble bone disease (synonym: Congenital osteosclerosis,giperostoticheskaya dysplasia, osteopetrosis, a disease Albers- Schönberg) - a disease in which the majority of bones produced an increased number of compact substance, in conjunction with the development of dense bone tissue in the bone marrow canals. The disease is attributed to a group of mesenchymal dysplasia of the skeleton, and is characterized by profound changes in calcium - phosphorus metabolism. In the zones and endosteal ossification develops enchondralsclerosal excess tissue. Specific features of the disease: pathological fractures of long bones, bone sclerosal mixed hydrocephalus, optic atrophy, hepatosplenomegaly, hypochromic anemia, primary immuno-deficiency conditions, delayed teething.