STUDY OF THE MORPHOFUNCTIONAL FEATURES OF THE ARTICULAR SYNDROME OF AUTOIMMUNE ORIGIN
This article discusses the features of the articular syndrome of autoimmune origin. Joint syndrome combines a complex of diseases that belong to the group of inflammatory joint diseases of the connective tissue or diseases of the musculoskeletal system, characterized by the development of chronic erosive arthritis. The most common inflammatory joint disease is rheumatoid arthritis (RA). As the history of human disease shows, the main threats of joint syndrome are complications of rheumatoid arthritis. RA is a complex, chronic autoimmune disease that affects 0.5-1% of the world's population. Rheumatoid arthritis is characterized by inflammation of the joints, causing bone resorption. In recent years, two variants of RA have been distinguished by the presence or absence of antibodies to cyclic centered peptide (ADC) and rheumatoid factor (RF). Research shows that the ADC test has a sensitivity and specificity that is no worse, and often even better, than during the RF test. In addition, according to most scientists, a blood test for ADC is more common than for the Russian Federation. The studies also noted that the highest percentage is available for analysis to the joint definition of the RF and ADC. The joint determination of RF and ADC allows to diagnose RA at the early stages of development, as well as to prescribe therapy in a timely manner and prevent severe destructive changes in the joints. A higher concentration of antibodies to ADC and the joint definition of RF and ADC indicates the presence of an inflammatory lesion of the joint membrane of autoimmune origin.