THE DETECTION RATE OF MARKERS OF ACUTE AND PERSISTENT RESPIRATORY INFECTIONS IN WOMEN DURING THE SECOND TRIMESTER OF PREGNANCY COMPLICATED WITH CHRONIC SIMPLE BRONCHITIS IN REMISSION
Serological, immunoenzyme and molecular genetic markers of viral infections in 100 women in the second trimester of pregnancy, uncomplicated and complicated by chronic simple bronchitis in remission, and in their full-term newborns were studied. The first group included 30 women with physiological pregnancy; the second group consisted of 38 patients suffering from chronic simple bronchitis out of exacerbation; the third group had 32 women with chronic simple bronchitis in remission and the threat of miscarriage in the second trimester of gestation. It was found out that in the second group there was one case of diagnosed signs of influenza A(H3N2), one case of influenza B, in 2 patients there was parainfluenza type 3 and in 1 case there was an acute phase of cytomegalovirus infection, in the absence of those in women of the first group. In the third group, asymptomatic influenza A(N3N2) (n=6), parainfluenza type 3 (n=8) and acute phase of cytomegalovirus infection (n=9) were more often observed and were found in patients of the second group, respectively, in 1 case (p<0.05), in 2 patients (p<0.05) and in 1 woman (p<0.01). At the same time, 2 patients of the third group had an exacerbation of herpes-virus infection (herpes simplex virus type 1). Thus, in women suffering from chronic simple bronchitis outside of exacerbation, the threat of interruption in the second trimester of pregnancy was associated mainly with the asymptomatic course of respiratory viral infection (influenza A(H3N2) and parainfluenza type 3), as well as exacerbation of persistent DNA viral infections.