NEW PHARMACOLOGICAL METHODS AND APPROACHES TO TREATMENT OF CHRONIC HEART FAILURE WITH LOW LEFT VENTRICULAR EMISSION FRACTION (REVIEW). PART 1
Heart failure with low left ventricular ejection fraction presents a serious problem for health care. Apart from being a serious reason for disease incidence and death rate, it is a substantial economic burden for health care system. In spite of considerable achievements in providing medical treatment, the prognosis for the patients is unfavorable. Re- hospitalizations of patients provoked by frequent exacerbation and acute attacks of the disease indicate both deterioration of life quality and even worse prognosis. In spite of optimal application of scientific achievements the clinical reality indicates both at unsatisfied demands and opportunities for health care improvement. This review demonstrates the capabilities of some cellular and molecular genetic technology and surgery techniques both at experimental research stage (including in vitro and laboratory animals) and preclinical and clinical research of medicinal and diagnostic agents.