ANTIDEPRESSIVE THERAPY IN PROCESS OF REHABILITATION OF OPIOID ADDICTED PATIENTS WITH EXPRESSED DEPRESSIVE SYMPTOMATOLOGY
The goal is to estimate efficiency of antidepressive pharmacotherapy at the stage of opioid addicted patients’ rehabilitation with expressed depressive symptomatology. 270 opioid addicted patients, receiving the medical-rehabilitation maintenance of different intensity and duration, are examined. 94 persons were under treatment of 10 days standard detoxication course and others 176 persons, except detoxication, have passed through Orthodox rehabilitation course of various (30–540 days) duration: 97 persons of the patients during first three months received antidepressive pharmacotherapy (cytalopram 40 mg per day), and 79 persons passed a rehabilitation course without pharmacotherapeutic supports. The analysis of frequency of cases of returning to the use of drugs and also indicators of quality of life in groups of comparison over a period of one-year after detoxication was carried out. It is proved, that even rather short course of antidepressive therapy in opioid addicted patients, with expressed depressive symptomatology, essentially increases their addiction to the rehabilitation program, their ability to abstain from the use of drugs and improves their quality of life.