THE ROLE OF GAS TRANSPORT FUNCTION OF ERYTHROCYTES IN THE PATHOGENESIS OF CHRONIC PLACENTAL INSUFFICIENCY IN PREGNANT WOMEN WITH HERPES VIRAL INFECTION
90 pregnant women were examined when they had 6-12, 21-24, 32-36 weeks of pregnancy. 30 women had an acute form of herpes viral infection (HVS-1,2) (the first group), 30 women had a stable remission (the second group), and 30 women were without any diagnosed infection (the third control group). In the peripheral blood of pregnant women of the first group, the number of erythrocytes, reticulocytes and the quantity of the whole hemoglobin fell in comparison with the second and the third groups (p<0,001), the quantity of oxyhemoglobin was lower by 1,2 than in the third group, and the quantity of methemoglobin was higher (p<0,001). The disturbance of metabolism in erythrocytes of pregnant women of the first group was identified by the rise of glycolysis 2,3-DPG metabolite and the drop of the whole ATP, which proves the disturbance of gas transport function of erythrocytes and is of importance in the pathogenesis of chronic placental insufficiency.