PHARMACOLOGICAL ACTIVITY OF NEW containing a metal DERIVATIVES OF NICOTINIC ACID
Among the 13 new physiologically compatible antioxidants (FSAO) revealed the complex compounds of copper under ciphers πQ-1032 and πQ-1033, which in extreme conditions latitude effective doses (10, 25, 50 and 100 mg / kg) and the degree of activity (increase of life span mice at 26-36% and an increase in the duration of the mice run on 20-74%) is superior to other tested materials and famous antihypoxants (mexidol and sodium hydroxybutyrate) and actoprotectors (bemetil and bromantan). πQ-1032 and πQ-1033 is recommended for further more in-depth study and possible use in the clinic as a corrector of pathological states that arise in extreme conditions.