REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN ANTERIOR UVEITIS PATIENTS
The purpose of the present research is to investigate the serum antibodies (Ab) levels dynamics of IgM and IgG classes to cytomegalovirus (CMV) in anterior uveitis patients by means of immune-enzyme assay. The level of specific antibodies to CMV was investigated using the immune-enzyme assay in paired serums of 37 anterior uveitis patients. Anterior uveitis patients were IgG class antibodies seropositive in 100% cases, while being IgM-sepositive only in 40.5% cases. The reactivation of latent CMV infection was established by IgG-class Ab seroconversion in 21.6% patients. The time of diagnostic procedures was shortened by a single-time immune-enzyme assay for CMV antibodies of IgG titres ≥ 1:12800 or IgM ≥ 1:800 in a single sample. Antiviral treatment is recommended to in patients with endogenic CMV uveitis in a latent CMV-infection reactivation stage detected by IgG-class Ab seroconversion.