INVESTIGATION OF ENANTIOSELECTIVE RETENTION OF PYRROLOQUINOLONES BY HPLC
Mechanisms of retention of model pyrroloquinolones on a chiral stationary phase with macrocyclic antibiotic ristocetin as function of mobile phase composition were studied by chiral chromatography. Snyder-Soczewinsky model was applied to describe the dependence of retention factor on the organic content in the mobile phase. Conclusions about the features of steric interactions in the studied system were made.