NEW IN CHEMOTHERAPY OF LIVER ECHINOCOCCOSIS
The article provides data on the study of the action of free albendazole and the liposomal form of albendazole (LFA) in experimental animals with liver echinococcosis. It was found that LFA has a more effective antiparasitic effect than the free form of albendazole. LFA is quickly transferred to the area of the parasitic cyst of the liver and has a detrimental effect on the scolexes and protoscolexes of the parasite. In the circumference of the echinococcal cyst, lymphoid and macrophage infiltration is observed. At the same time, in the hepatic tissue, the beam structure is preserved, the expansion of the Disse space, hypertrophy of the hepatocyte nuclei are noted. In general, LFA opens up new possibilities for chemotherapy of hydatid liver echinococcus.