ANALYSIS OF HOSPITAL MORTALITY IN INFECTIVE ENDOCARDITIS
Objective: To identify predictors of mortality risk in patients with infective endocarditis (IE) in the hospital.The analysis of 302 patients with a documented observations of native valve IE, hospitalized in Regional Clinical Hospital of Saratov from 2000 to 2014. Two groups of patients depending on the outcome of patient treatment: survivors (n = 243) and died (n = 59). Hospital mortality in patients with IE was 19,5 %. Analyzed the differences of quantitative and qualitative traits characterizing IE: demographics, valve lesion localization, vistseropatii, echocardiography parameters. According to the results of logistic regression with the onset of death in IE in the hospital were independently associated increase in end-diastolic left ventricular size (OR 2,77; CI 1,37–5,59; p = 0,005), systolic pulmonary artery pressure (OR = 1,056; CI 1,022–1,091; p = 0,001), peripheral blood leukocytosis (OR 1,2; CI 1,1–1,4; p < 0,0001) and neurological disorders (OR = 17,04; CI 4,65–62 4; p = 0,0003). These figures reflect the activity of systemic inflammation in IE, hemodynamic abnormalities, complications, the most serious of which is the central nervous system.