EVALUATION OF THE PREVENTIVE COMPLEX EFFICIENCY IN THE HIGH-RISK PUERPERAS OF EARLY HYPOGALACTIA BY METHODOLOGICAL STANDARDS OF EVIDENCE-BASED MEDICINE
To evaluate the effectiveness of the developed complex method for the pathological course of lactogenesis, we examined 200 puerperas with placental insufficiency (PN) of varying severity. Ninety women refused preventive measures, 110 women underwent preventive therapy with a developed complex method, 40 women with the physiological course of gestation constituted a control group. In the dynamics of the postpartum period, we assessed the lactational function of mammary glands in women of comparison groups by determining the daily milk volume, the qualitative composition of the mammary glands secretion, evaluation of clinical signs of pathological lactogenesis, and determination of the prolactin level. The obtained results of the study confirmed the negative effect of the complicated pregnancy on the lactation function development. The developed preventive complex appears to be effective against the pathological course of lactogenesis. This was confirmed by the methodological standards of evidence-based medicine (NNT = 1.64, 95% CI 1.37-1.88, OR = 21.5, 95% CI 16.4- 27.3).