PLEIOTROPIC EFFECTS OF THE THERAPY BASED ON INKRETINOMIMETIK IN PATIENTS WITH TYPE 2 DIABETES MELLITUS COMPLICATED BY NEUROPATHY AND HEPATIC STEATOSIS
Analysis of clinical efficacy of combination of inkretinomimetik exenatid and metformin from 30 type 2 diabetes mellitus complicated by neuropathy and hepatic steatosis. For generalization conditions of patients used standard questionnaires neuropatic complaints and ehogepatodensitometria. After a 12-week course of treatment of distal occurrence demonstrated the degree of polineuropatia in patients with diabetes mellitus type 2 and dyslipidemia decreased significantly: on the scale of the dysfunctional neuropatia accounts with 37,9% to 8,2%, on the scale of the modified dysfunctional neuropatia account – with 41,4% to 6,9%. The positive dynamics was observed in almost all clinical-neurological performance scale NTSS-6. Changes ehogepatodesitometria rates after treatment showed decreasing deposition of fat in the liver. It is proved that in addition to control glycemia in the use of combination therapy for 3 months has a positive effect on the distal sensory-motor polineuropathy and hepatic steatosis.