The impact of combination therapy on сentral blood pressure and arterial stiffness
The progression of arterial stiffness, increased distribution velocity of the pulse wave is determined the level of the central blood pressure (BP), which is an integral indicator of remodeling the vascular bed and has a high prognostic value in respect to the defeat of target organs, and outcomes at arterial hypertension than peripheral pressure. In this connection, increasing scientific interest is the study of the effects of antihypertensive therapy on central blood pressure and parameters of arterial stiffness. Therapy of fixed combination of lisinopril/amlodipine/rosuvastatin leads to a significant reduction of peripheral and central BP, with a more pronounced effect on central BP, decreased arterial stiffness, and additional assignment of is accompanied by a trend towards more pronounced effects.