THE MEDICAL IMPORTANCE OF CONDITIONALLY PATHOGENIC STRAINS OF YERSINIA ENTEROCOLITICA
Analysis of scientific studies on the virulence of Yersinia enterocolitica strains of biovar 1A (considered non-pathogenic ear liar) was carried out. However, thermostable enterotoxin YST B (Yersinia Stable Toxin), which has a strong toxic effect and can cause diarrhea in humans and animals was found in many strains. In the PCR studies, for 87.1% of the 116 Yersinia enterocolitica strains of biovar 1A of different origin and territorial distribution the chromosomal gene of thermostable enterotoxin yst B was revealed. On the model of newborn mice, signs of enterotoxigenicity were detected in a part of the strains both at 26 ° C and at 37 ° C. The presence of enterotoxigenicity in Yersinia enterocolitica biovar 1A showed their possible role as etiological agents in diseases of the gastrointestinal tract and the musculoskeletal system. There are few clinical descriptions of infectious diseases, including arthritis, where Yersinia enterocolitica biovar 1A was identified as the sole causative agent. Even less information about the etiological role of Yersinia enterocolitica-like in human pathology. At the same time, the share of their discharge from environmental objects, from people and animals increases. Unfortunately, experimental studies on the presence of pathogenic properties of Yersinia enterocolitica-like bacteria in available scientific sources have not been found. Studies with the latest pathogens of yersiniosis are conducted, especially among children and in organized groups. Based on the above data, we can assume the etiological role of Yersinia enterocolitica biovar 1A and Yersinia enterocolitica-like in medical practice.