Non-Saponifiables of Avocado and Soya Bean: the First-Line Therapy of Chronic Musculoskeletal Pain
Analgesia is an essential part of the management of musculoskeletal system disorders (osteoarthritis and nonspecific back pain). Due to multifactorial pathogenesis, therapy of pain is multicomponent, involving agents with different mechanisms of action. Non-steroidal anti-inflammatory drugs (NSAIDs) are first-line therapies. Chondroprotective agents are characterized by slow-onset anti-inflammatory effects and may be used for single-drug therapy or in combinations with fast-acting analgesics in the management of chronic pain. The article analyses clinical value of non-steroidal anti-inflammatory agent ketoprofen lysine salt (Artrosilen) and chondroprotective preparation of non-saponifiables of avocado and soya bean (Piascledine).