CHRONIC PANCREATITIS AS A PREDICTOR OF OSTEOPOROSIS FORMATION
The issues of formation of secondary osteoporosis in patients with chronic pancreatitis (CP) were discussed in this paper. It was shown that the chronic relapsing nature of the disease process in the pancreas leads to hypokalemia due to malabsorption of calcium and vitamin D as the result of maldigestion. As well as the redistribution of ionized and total calcium blood between the body fluids, which can be a consequence of long-term nature of pain. At the same time, the study of the content of enzymes bone found their decline to a greater extent characteristic index tartrate resistant acid fosfatazy- marker of bone resorption. Changes in bone metabolism were confirmed by ultrasound bone (densitometry) at which proved the development of osteoporosis in 47,7% of cases, and osteopenia in 35,7% of patients. The conclusions about the need for pre-clinical diagnosis of osteoporotic states in patients with CP, correction of diet and administration of appropriate therapy were made.