ANTIGENIC ACTIVITY OF INACTIVATED RIFT VALLEY FEVER VIRUS
The paper presents some results obtained on a Rift Valley fever virus inactivation which allow production of an inactivated raw virus preserving its antigenic and immunogenic activity levels. The diethylenimine- and A-24-inactivated preparations induced complement-fi xation and haemagglutination antibody synthesis at a rate of 1:256-512 and 1:512-1024, respectively on day 21 to 28 post their inoculation to mice or sheep. The vaccinated mice were resistant to challenge with a virulent virus strain at a dose of 1000 LD50.