Assessment of the State of the Implanted Stents with the Method of Optical Coherence Tomography in 6 Months after Implantation in the Area of Recanalized Chronic Occlusions of Coronary Arteries
Purpose. To assess the condition of implanted stents with optical coherence tomography in 6 months after implantation into the area of recanalized chronic total occlusions of coronary arteries. Materials and methods. The study included 103 patients, who underwent coronary artery CTO recanalization in the period from 2009 to 2012. In 6.1±0.9 months, all patients were examined with coronary optical coherence tomography. Results and discussion. All patients had the adequate apposition of previously implanted coronary stents, which was confirmed by characteristics of linear parameters, in-stent area, and the stent symmetry index. The maximal, minimal diameter, and lumen area were significantly lower (p <0.05) after implantation of trapidil and sirolimus eluting stents. The neointima area in the group of trapidil eluting stents was 4.60 (3.69; 5.77) mm2, in the group of sirolimus eluting stents it was 2.34 (1.98; 3.02) mm2, which was significantly higher (p<0.05), if compared with patients after implantation of paclitaxel, zotarolimus, everolimus and biolimus A9 eluting stents. A minimal amount of malapposed, protruded and uncovered struts was observed after implantation of trapidil and sirolimus eluting stents. The presence of small parietal thrombi was significantly more common after implantation of the 1st generation paclitaxel eluting stents (4.89%, p<0.01 in comparison with other stents).Conclusions. The obtained data indicate the significant fibro-proliferative changes after the use of trapidil and sirolimus stents, which was not observed in patients, who received paclitaxel, zotarolimus, everolimus and biolimus A9 eluting stents. This lets to clarify the development mechanism of the target lesion failure in the mid-term period after implantation of trapidil and sirolimus eluting stents in the recanalized CTO zone.