COMPARING THE GROWTH INHIBITION RATE OF MODERN ANTISEPTICS ON ESCHERICHIA COLI, STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA WITH A VIEW TO THEIR USE FOR INFECTED WOUNDS
The article presents the results of a study of solubility of modern antiseptic octenidine dihydrochloride in combination with various surfactants and polihexanide. Antimicrobial effect was investigated for individual substances and their mixtures. Octenidine and polihexanide represent a new generation of antiseptics, characterized by a broad spectrum of activity and low cytotoxicity at the same time. It is known that octenidine acts faster than polihexanide. According to our hypothesis, the combination of these two substances could have an even greater antimicrobial activity than a single substance. The results obtained in the laboratory, confirmed that the mixture of octenidine and polihexanide has a stronger antimicrobial activity. This mixture can be used in various medical products, and especially in conjunction with wound dressings for the control of microorganisms in chronic wounds.