Efficacy of different regimens of thromboprophylaxis in real clinical practice (retrospective study)
Aim. To evaluate the efficacy of biosimilar enoxaparin and unfractionated heparin in thromboembolism prophylaxis in preoperative period.Material and methods. 243 orthopedic patients were included in retrospective study. Doppler ultrasound examina- tion was perfomed in all patients. The main criterion of effica- cy was the absence of deep vein thrombosis before surgery. Results. Venous thrombosis incidence was similar in patients treated with unfractionated heparin and biosimilar enoxaparin.Conclusion. No significant benefits over standard heparine were found in patients treated with biosimilar enoxa- parine. This result may be due to the heterogeneity of raw material used for production of original and biosimilar enoxa- parin.