MULTIMODAL INTRAOPERATIVE NEUROMONITORING AND NEUROPROTECTION METHODS DURING EXTRA CRANIAL FRTERIES SURGERIES
The valuation of the efficiency of multimodal neuromonitoring and cerebral protection was carried out on patients, who had different extra cranial arteries surgeries. The standard methods of brain protection were used within the main group on patients during carotid artery cross-clamping. In addition to standard complex of neuro protection, perfluorane emulsion was injected to patients on the basis of 5 ml/kg of body weight. The degree of brain damage has been estimated by the level of – neurospecific protein (S-100, NSE), blood lactate concentration from internal jugular vein. Brain oxigination has been estimated by the cerebral oximetry indexes. Cerebral oxygenation was stable within the control group during all stages of the surgery. The level of a neurospecific proteins indicated the high level of specificity and sensitivity regarding to intraoperative brain damage. The multimodal neuromonitoring can be reasoning for neuroprotection enlargement at the expense of perfluorane infusion.