Efficacy of a novel immunomodulatory therapy for multiform exudative erythema
The aim of the present work was to substantiate the necessity of applying Panavir for treatment of multiform exudative erythema, as well as to study its clinical efficacy. 36 patients with multiform exudative erythema were kept under clinical observation. During the examination, the level of cytokines in blood serum and the content of the soluble antigens CD50 and CD54 were determined; immunophenotyping of peripheral blood mononuclear cells was carried out by indirect immunofluorescence. It was demonstrated that the imbalance of cytokines and the system of antigen adhesion play a key role in the occurrence of pathologic changes in patients with multiform exudative erythema. The application of Panavir promoted recovery of all patients under observation