ROLE OF IMMUNOPHENOTYPING OF BONE MARROW AND LIQUOR CELLS IN THE DIAGNOSIS OF MULTIPLE MYELOMA AND PLASMA CELL LEUKEMIA
Multiple myeloma is one of the nosological forms of lymphoproliferative disease, and plasma cell leukemia is treated as one of the variants of rare and very aggressive B-cell lymphoma. The diagnosis of paraproteinemical of hemoblastosis standard cytological and histological methods of research in 30% of patients causes difficulties. Immunophenotyping of bone marrow cells plays an important role in the diagnostics of paraproteinaemic haemoblastoses. Marked by features of expression of antigens by myeloma cells of the bone marrow with multiple myeloma and plasma cell leukemia. A case report of neuroleukemia extramedullary relapse in plasma cell leukemia patient in an immunochemical remission after bone marrow autotransplantation undergoing immunophenotyping of liquor is presented in the following article.