The efficacy of a combined calcium-D3 preparation in children with decreased bone strength
The article for the first time presents data about the state of bone strength in children who consume less calcium than the agerelated norm and have a higher risk for bone fracture. As has been found, in children with a high fracture risk the values of bone strength below the 10th percentile are recorded considerably more frequently than among the population. It has been proven that consumption of dietary calcium less than 600 mg/day is a risk factor for a decrease of bone strength and for fractures of tubular bones. The efficacy of administering a combined preparation containing calcium and vitamin D3 to children with dietary calcium deficiency has been established. Intake of the drug in the dose 1000 mg of ionized calcium and 400 IU of vitamin D3 promotes enhancement of bone strength, optimization of the processes of bone remodeling and mineral metabolism. The effectiveness of the drug has been proven by application of modern methods of statistical processing of clinical material, including calculation of odds ratio, the values of a decrease of relative and absolute risks.