CONTRAST-COLOR SENSITIVITY AS BIOMARKER OF HEMODYNAMIC CONDITION IN SYSTEMIC CIRCULATION AND IN SMALL VESSELS
Basing on the analysis of indices of the contrast-color sensitivity of visual system a quantitative estimation of age-related sensitivity changes, of sensitivity changes in people having different levels of blood pressure and of sensitivity changes in ill and healthy eyes of patients with acute and chronic ischemic optic neuropathy has been carried out. The dependence of the light sensitivity on the vessels diameter of the eye retina has been analyzed, too. The differences found between the changes in these functional parameters of the visual system light sensitivity have been used for discussing the biomarker role of the contrast-color sensitivity for revealing of age-related changes in the visual system hemodynamics and its changes when the small vessels are damaged resulting in development of ischemic optical neuropathy. The possibilities of using the data of contrast-color sensitivity decrease in the early diagnosis of hemodynamic impairments in the systemic and microcirculation beds are discussed.