Metastatic triple negative breast cancer: current approaches to therapy
Treatment of patients with triple negative breast cancer (TNBC) remains one of the most difficult problems in clinical oncology. This type of BC combines biological aggressiveness and limited number of treatment modalities, and often affects young women. From the great arsenal of the contemporary BC treatment methods only chemotherapy is appropriate for TNBC. Despite the great number of clinical studies devoted to TNBC, there is no standard chemotherapy regimen for this subtype, and the results of treatment remain unsatisfactory. The principles of maximal individualization of BC therapy are not successful for the triple negative subtype. The article presents the review of the most significant clinical studies of recent years devoted to metastatic TNBC.