THE ROLE OF ARTIFICIAL HYPERGLYCEMIA IN IMPROVING THE EFFICIENCY OF RADIATION-, THERMORADIATION AND CHEMOTHERAPY OF TUMORS
This review analyzes the pH state of the tumor and normal tissues in experimental animals and humans. It was found that the pH level in a number of malignant tumors is significantly lower than in surrounding normal tissue, and artificially created hyperglycemia may lead to its further reduction and strengthening of the damaging effect of radiation, hyperthermia and some chemotherapy agents for tumors. This is evidenced by not only the results of experimental studies, but also the data of some clinical studies in patients with cancer of oral cavity, oropharyngeal area, lung, mamma and rectum.