Modern view on the Solved and Unresolved Diagnostics Problems of Acute Hepatic failure
Acute hepatic failure is a result of a large number of diseases and conditions accompanied by hepatic necrosis. Its main cause is various kinds of viral hepatitis. The pathogenesis is based on necrotic processes, apoptosis, and necroapoptosis of hepatocytes. Treatment of acute hepatic failure is complex and includes salvage treatment, efferent therapy and methods of gravitational surgery. Liver transplantation is the only radical kind of treatment. The main reasons for mortal- ity in this pathology are cerebral edema with a subsequent brainstem herniation, gastrointestinal bleedings, infectious complications and multiple organ failure. The AHF prognosis is individu- al for each particular case despite the existence of enough scales and criteria.