STUDY OF WOUND-HEALING EFFECT GEL, BASED ON CHITOSAN TAURINE AND ALLANTOIN
In the screening studies of a full-thickness skin wound model, studied wound healing effect of the combination gel based on сhitosan with taurine and allantoin in comparisons with gel Solcoseryl and ointment Levemecol. effect, reduces the period of recovery for 4 Determined that the gel based on chitosan containing taurine and allantoin has a pronounced wound-healing days, increasing the rate of wound healing by 1.5 times compared to the control and provides complete epithelialization of the wound defect. Wound healing after application of the gel based on chitosan with taurine and allantoin to 9 hours more efficiently with respect to gel "Solkoseril" and ointments "Levomekol" on 25,38% and 40,24% (p <0,05), respectively, without forming the rough connective tissue scar. According to histological studies revealed that the developed gel accelerates remodeling of scar tissue, stimulates the regenerative processes and promotes the transformation of scarring in the skin regenerates type.