IGG4 - associated pathology. clinical observation of the disease of ormondo-retroperitoneal fibrosis
In the last decade, a new nosological unit has been identified - IgG4-associated systemic disease (IgG4-CVD). This is a group of pathologies that have two similar features: an increase in the concentration of immunoglobulin G (IgG) of the 4th subclass in the serum and the formation in various organs and tissues of infiltration from plasma cells secreting IgG4, eosinophils, the development of fibrosclerosis and obliterating phlebitis. IgG4 CVD is characterized by a variety of clinical manifestations, the number of which is constantly growing. There are both forms with one lesion localization and multi-organ manifestations, traditionally called multifocal fibrosclerosis. The article presents a clinical case of the disease of Ormondo- retroperitoneal fibrosis, discusses the problems of diagnosis and treatment.