SLEEP DISORDERS AND SHARP HEART DISEASE (epidemiological study based on the WHO program "MONICA")
The purpose of the study. Study of influence of sleep disorders on the risk of myocardial infarction within 8 years in men aged 25-64 years. Materials and Methods. The WHO Programme «MONICA - psychosocial” in 1994 was conducted a screening study of the male population aged 25-64 years residents of one of the districts of Novosibirsk. Cohort was monitored for 8 years (1994-2002) to determine the endpoint (myocardial infarction), statistical analysis was performed using the software package «SPSS-10.» Cox proportional regression model was used to estimate relative risk. Results. Only one third of men aged 25-64 years with newly emerged MI, regarded the dream as «good», and two thirds had sleep disorders. The relative risk of myocardial infarction in men aged 25-44 years during the 8-year period was 9.25 times higher than the assessment of sleep «bad» than «good», ie in this age group sleep disorders are one of the major factors leading to the occurrence of myocardial infarction; aged 45-64 years, these differences were not significant. The risk of myocardial infarction in patients with sleep disorders was higher in males widowed, divorced, those with low levels of social support, with the initial level of education, belonging to the group of working professionals and retirees. Conclusion. The results suggest that sleep disturbance, primarily a social problems, contributes significantly to the risk of myocardial infarction in men of the youngest age group.