Organogenesis parallel in vital cycle of oviparous and viviparous amniotes primary kidney
Aim. To identify morphogenetic and morphometric markers of organogenesis parallel in urine organ and structure unit development (poultry primary kidney and human primary kidney). Material and methods. We studied 268 poultry embryo (age: 48 hours - 20 days), 127 human embryo (12-23 Carnegie stage (CS)) and 28 human fetus (9-12 week). All material is formalin-fixed and paraffin-embedded, H&E-stained and PAS-stained. We used light microscopy and morphometric analysis. Results. 1. An analysis of the material revealed essentially identical organogenesis stages of poultry primary kidney and human primary kidney, as well as comparable patterns of mesonephronogenesis. It is shown that the principle of parallelism is implemented not only at the tissue, but also at the organ level of the morphological substrate evolution. 2. There were identified organotypic differentiation variants of the intermediate mesonephral mesenchyme: the primitive exocrine glandular structures formation, the construction of mesonephrons that perform the urination function, the construction of megalotypic nephrons, and nephronogenesis of poultry primary kidney is accompanied by the ventrodorsal generation formation. 3. Morphometric markers revealed a direct correlation at the transformation stages of the renal corpuscles and tubules of the poultry and humans primary kidneys. Conclusion. The patterns of morphological and morphometric signs at the vital cycle stages of the oviparous and viviparous amniotes provisional urination organs indicate the objective existence of the organogenesis parallelism phenomenon during the development and organs evolution - the structural organization leading form of the mammals and birds body.