Extracorporeal detoxification in cancer patients
The modern approaches to extracorporeal detoxification in intensive care of cancer patients are reviewed in the article. Life-threatening disorders of homeostasis in these patients is a leading cause of reduced effectiveness of treatment of the underlying disease and increased mortality. Moreover, these disorders may be the result of decompensation of comorbid diseases or develop at any stage of treatment of cancer. The authors analyzed the methodology of surgical and drug treatment of cancer patients with end-stage chronic renal failure receiving hemodialysis. Data on modern extracorporeal detoxification methods in patients with paraproteinemic hemoblastoses and advanced release of free light chains of immunoglobulins are presented. The achievements of recent years in intensive therapy of sepsis following cancer are presented. The authors consider special indications for emergency extracorporeal detoxification in cancer patients without classical signs of organ decompensation. Perspective developments in extracorporeal detoxification issues including combination with antitumor treatment are indicated.