SUCCESSFUL PREGNANCY AND CHILDBIRTH IN PROGRAMS USING CALCIUM IONOPHORE, IN PATIENTS WITH A LACK OF FERTILIZATION IN PREVIOUS PROGRAMS BY INTRACYTOPLASMATIC SPERM INJECTION WITH NORMOZOOSPERMIA
The lack of fertilization is the biggest problem in assisted reproduction technology. The main causes of fertilization failure in conventional IVF are low sperm count and sperm morphology. However, in 2-3% of cycles using ICSI programs, with normal spermogram values and normal sperm morphology, there is a complete or partial absence of fertilization of mature oocytes. The main reason is the lack of activation of the oocyte during fertilization.The purpose of this work is to report on successful pregnancies and deliveries after the application of calcium ionophore to activate oocytes with normozoospermia in patients with no fertilization in previous programs using the intracytoplasmic injection method (ICSI). The theoretical and practical substantiations of the application of this method are given.