The risk of cardiovascular diseases and intracellular metabolism under obesity in males
The obesity is the main manifestation of metabolic syndrome. It is followed by oxidative stress. The neutrophils can become markers reflecting presence of oxidation stress under obesity. The sampling included 103 males aged from 23 to 64 years without ischemic heart disease. The examination was targeted to presence of obesity, factors of antirisk of cardio-vascular diseases and metabolic activity of neutrophils. It is established that obesity in males results in activation of oxygen-depended metabolism of neutrophils and is associated with more rare every day usage of raw vegetables or fruits and low physical activity. In patients with obesity stage III increasing of formation of oxygen radicals in neutrophils followed by decreasing of activity if intracellular antioxidant defense hence supporting development of oxidative stress. In males with peripheral obesity, the level of antioxidant defense of neutrophils is an indicator of possibility of formation of cardiovascular pathology.