LIMBIC ENCEPHALITIS. LITERATURE REVIEW AND CASE REPORTS
Limbic encephalitis (LE) is a rare neurologic syndrome that is characterized by subacute memory loss and other cognitive impairments, psychiatric disorders and epileptic seizures. Besides it can manifest with dyskinesia, autonomic and endocrine disturbances. In the most cases the disease has paraneoplastic genesis but nowadays there are a lot of cases of idiopathic autoimmune limbic encephalitis associated with antibodies to the neuronal membrane proteins. The article presents review of symptoms and treatment of different types of LE. We present two case reports: the first case is associated with a caecum adenocarcinoma, and the second case is an idiopathic one. In the first case the improvement was seen after radical resection of the tumor and in the second case — on levetiracetam treatment without immunosuppressive therapy.