STUDY OF ANTIOXIDANT PROTECTION ENZYME ACTIVITY AND CYTOKINE LEVELS IN OSTEOARTHROSIS PATIENTS TREATED WITH WOBENZYME
The aim and task of the present work was to study the catalase enzymes and superoxide dismutase (SOD) in plasma and erythrocytes, levels of IL-1, FNO-, IL-4 cytokines in blood plasma in primary arthrosis patients observed in dynamics with wobenzyme administration. M.A. Korolyuk method was applied for catalase investigation, cytokines were researched by immunoenzyme analysis method. 38 Increased levels of IL-1, FNO- more than double-fold and a reduction of antioxidant defense enzyme activity (P< 0.05) were revealed. Wobenzym usage contributed to a more effective increase in the activity of erythrocyte catalase and IL- 4 level, as well as a reduction of IL-1 volume.