Synthesis and antimycobacterial properties of fluoroaryl-2-isoxazolines
New compounds containing fluoroaryl-2-isoxazoline moiety have been synthesized and their antimycobacterial properties have been studied. The key step in their synthesis was 1,3-dipolar cycloaddition of corresponding nitrile oxides derived from 4-methoxy-3-fluorobenzaldehyde or 4-methoxy-2,3-difluorobenzaldehyde oximes, to allyl alcohol.