EFFECT OF L-ARGININE THERAPY ON THE LEVEL OF STABLE METABOLITES OF NITRIC OXIDE CYCLE, ENDOTHELIAL DYSFUNCTION MARKERSAND INDICATORS OF OVARIAN HEMODYNAMICS AT WOMEN WITHPOLYCYSTIC OVARY SYNDROME
It was found that women with PCOS have hier levels of the NO metabolites and loweredconcentration of the L-arginine in the blood serum. Application Tivortin leads to an increaseL-arginine, reduces of NOx and improves endothelial function by reducing endothelin-1, endothelialgrowth factor and homocysteine in blood. The therapy leads to decreases number of antral folliclesin the ovaries, improves hemodynamics in the ovarian vessels: reduced peak systolic and end diastolicvelocity, resistance index.