Biochemical markers of bone turnover for osteoporosis in women: utility in diagnosis and therapy monitoring
Diagnosis of osteoporosis is based solely on dual-emission X-ray absorptiometry-based measurements of bone mineral density. However, within the last 20 years, biochemical markers of bone turnover have been implemented to a larger degree within the field of predicting patients at high risk of losing bone, future fracture events and especially drug development. This review evaluates the use of bone turnover markers as aids in diagnosis and monitoring response to treatment in patients with osteoporosis.