CHANGES IN THE CONTENT OF BIOGENIC AMINES AND THEIR RATIO IN ADRENAL GLANDS AND THE THYMUS UNDER WATER-IMMOBILIZATION STRESS
The thymus and adrenal glands of 40 female rats were studied using luminescent histochemical methods. The animals were divided into two groups: intact animals and rats subjected to water-immobilization stress lasting one hour daily during 10 days. Animals were withdrawn from the experiment in 1, 2 and 3 months after the end of exposure. It is established that water-immobilization stress changes the mass of organs, the level of biogenic amines in the thymus and adrenal glands, the ratio (CT+GST)/KA and the number of luminescent granular cells. Both in the thymus, and in the adrenal glands, all changes are of wavy and opposite character and depend on the phase of the stress reaction. The alarm phase was registered by us in rats in 1 month after the end of exposure, in 2 months later - the phase of resistance. In 3 months the phase of exhaustion forms.