WHAT IS NEW IN THE MANAGEMENT OF TYPE 2 DIABETES MELLITUS WITH OVERWEIGHT
It is important for the treatment of type 2 diabetes mellitus with overweight to use the drugs that contribute to the weight loss. Along with the widely used metformin, the following drug classes should be mentioned: GLP-1 receptor agonists, inhibitors of DPP-4, SGLT-2 and intestinal alpha-glucosidase. Hypoglycemic effects of the two latter classes are unrelated to the stimulation of the insulin secretion by beta cells. Other things being equal, drugs acting without stimulation of insulin secretion are preferable. Goals of glycemic control need to be individualized considering the age, prognosis, presence of macrovascular disease, and risk of hypoglycemia.