MORPHOLOGICAL CHANGES IN PATIENTS WITH A COMBINATION OF LOWER LIMB VARICOSITY AND OSTEOARTHRITIS OF THE KNEE
Purpose – To assess the histological changes that have occurred in patients suffering from varicose veins, and the combination of osteoarthritis of the knee and to compare them with the changes taking place in patients with no signs of osteoarthritis of the knee and chronic venous insufficiency.
 Methods – A total of 15 patients suffering from varicose veins, in combination with osteoarthritis of the knee and 11 patients with post-traumatic changes in the knee with no signs of chronic venous insufficiency. Evaluated the histological changes occurring in tissues paraartikulyarnyh.
 Results – In patients with a combination of varicose veins and gonarthrosis have the distinct signs of venous outflow, which is not observed in patients with posttraumatic changes.
 Conclusions – a violation of the venous outflow may be one reason for the development of osteoarthritis of the knee.
 In our opinion, these results suggest that patients suffering from varicose veins, and the combination of osteoarthritis of the knee in the present paraartikulyarnoy tissue changes characteristic of disorders of the venous outflow from the area. At the same time in patients who had no signs of osteoarthritis and chronic venous insufficiency, such changes are absent or much less pronounced. 
 Thus, we can say that the development of venous outflow patients is one of the predisposing factors for the development of osteoarthritis. The absence of these disorders is more common in patients without clinical and instrumental signs osteoatroza knee.