DETERMINATION OF TAMSULOSIN HYDROCHLORIDE RELEASE PHARMACOKINETICS IN PROSTATE GLAND BY RADIOTRACER METHOD
A study of pharmacokinetics of tamsulosin hydrochloride accumulation into prostate gland after oral and rectal administration by a radiotracer method with the aid of α-β-radiometer NRR-610 “Tesla” has been done. The research results proved the advantages of rectal route of drug administration compared with oral. The obtained results confirm the expediency of creation of the medicinal drug with alpha-adrenoceptor tamsulosin hydrochloride in the form of suppositories for prostate diseases treatment.