Detection of DNA of TT and SEN viruses in patients with liver diseases and blood donors
Recently discovered TT and SEN viruses are often detected in patients with liver diseases and in the general population, but the frequency of detection was not studied in the Republic of Belarus, and their clinical significance remains unclear. We have selected and implemented a technique of identification of the DNA of TT and SEN viruses using the polymerase chain reaction. The incidence of these infections in 138 patients with liver disease and in 47 blood donors was assessed. The detection rate of TTV in patients with liver disease is 48.6%, in blood donors - 38.3%. SENV DNA was detected in 66% of blood donors and in 46.4% of patients. The chances of TTV DNA detection were 2 times higher in patients with the markers of parenteral viral hepatitis.