INTERACTION OF PHOSPHONIUM SALTS WITH MEMBRANE LIPID COMPONENTS
The mechanism of interaction of quaternary phosphonium salts with biological membranes was studied on a model of Langmuir monolayers. Phosphonium bromides were ascertained to interact with lethicin and to be able to incorporate into the lipid layers of biological membranes. The effect of phosphonium bromides on the structure of biological membranes may offer an explanation of their antibacterial and fungicidal effects.