MODIFICATION OF THE METHOD FOR DETERMINING RESIDUALS OF TETRACYCLINE GROUP IN MILK BY HIGH PERFOMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY
A method for determining residuals of tetracycline group in milk by high performance liquid chromatography-mass spectrometry has been developed. The method is based on the extraction of tetracycline with buffer solution, as well as on the clearing the extract with solid phase extraction and quantitative analysis by high performance liquid chromatography - mass spectrometry. The recovery of the internal standard from milk with buffer solution was 92 %.