Non-viral liver diseases: pathogenetic approaches to therapy
Alcoholic liver disease and non-alcoholic fatty liver disease are chronic non-communicable diseases with an extremely high prevalence among the world's population. Currently, there is a tendency to a rapid increase in their number with frequent disability of patients and a high need for liver transplantation. Violations of the main metabolic processes in the liver under the influence of exogenous and endogenous factors are the starting point in the development of alcoholic and nonalcoholic liver pathology. This review discusses the main recommendations for non-drug and drug management of patients with liver diseases of non-viral etiology with a detailed description of the main hepatoprotectors with an emphasis on the universal properties of silymarin.