STRUCTURAL AND FUNCTIONAL ORGANIZATION OF EPILEPTIC FOCUS
This review represents current understanding of epileptic focus organization. It provides an insight into the concept of epileptogenic zone, developed by Hans otto Luders. According to this concept several zones defining the pathogenesis of epilepsy are defined, as well as the complex of clinical and instrumental presentation of epilepsy. These zones should be localized during preoperative evaluation of a patient with drug-resistant epilepsy. A crucial component of successful epilepsy surgery is the determination of the seizure onset zone. Resection or disconnection of this zone is associated with better seizure outcome.