Genetic markers of periodontal disease: a literature review
This review presents some data on the genetic markers of periodontal disease over the last few years. Most of the work is devoted to relationship of various interleukins polymorphism with periodontal disease. Also there are some information about relative polymorphism metalloproteinases, vitamin D receptor, defensins, Toll-like receptors and others. The relationship is explained by race, the combined effect of specific combinations of multiple allelic genes and trace components interact exogenous and genetic factors.