Possibility of use of MMP-7 (matrilysin) as a predictor of spread of tumor processes in patients with stomach cancer
The paper evaluates the levels of gene expression of matrix metalloproteinase-7(ММР-7) in biopsy specimen of the primary tumor and peritoneum of patients with resectable gastric cancer stages IIA-IIIC. It is noted that the overexpression of MMP-7 in the primary gastric tumor (adenocarcinoma) is a component of an aggressive phenotype, and the latter has the effect of the high ability to progression of the disease, despite the radical nature of the treatment.