A CLINICAL CASE OF PAROXYSMAL MYOPLEGIA, HYPOKALEMIC FORM IN A 17-YEAR-OLD PATIENT
Periodical paralysis, or paroxysmal myoplegia, is a unifying term for a group of rare hereditary diseases that are characterized by attacks of flaccid paralysis of skeletal muscles due to the pathology of sarcoplasmic ionic channels. Paroxysmal myoplegia disrupts the penetration of chlorine, sodium and calcium into the cell, which leads to depolarization of the membrane with subsequent reduction of sarcolemma excitability and development of paresis [1]. Depending on the serum potassium content, paralysis is usually divided into hyperkalemic (Gamstorp disease), hypokalemic (Westfal-Shakhnovich's disease) and normokalemic. In addition, periodic paralysis can be primary (genetically determined) or secondary.