Molecular-cellular mechanisms of transformation of homeostasis of biosystems with reactive oxygen species and nitrogen
The aim of this work was integration of clinical and experimental data about molecular, cellular and organismic effects of oxygen and nitrogen reactive species for its complex medical use. The basis for this paper was longitudinal experience of ozone use in different fields of experimental and clinical medicine, and investigation of physical chemistry and physiology of nitric oxide. We executed comparison of different oxygen and nitrogen reactive species (produced with some generators or chemical synthesis) effects to abiogenic and biological systems. Prolongation of investigations of molecular and cellular effects of physical factors-bioradicals could be useful for generation of new technologies in traumatology, combustiology and restorative medicine.