METABOLIC MARKERS OF CONNECTIVE TISSUE USED IN DIAGNOSTICS AND EVALUATION OF GROWTH INTENSITY OF UTERINE FIBROID
Here we studied concentration of degradation products of organic matrix released from connective tissue in 78 patients with uterine fibroid, aged between 32-55 years. Substantially increased concentrations of glucuronic acids and glycosamines were detected both in local (uterine veins) and systemic (ulnar veins) bloodstream of patients with fibroids. We have showed that intensity of accumulation of glucuronic acids was directly related to the fibroid growth rate as well as duration of disease.