THE STATE OF LOCAL ORAL CAVITY IMMUNITY IN THE SUBJECTS USING ANTISEPTIC TOOTHPASTES AS THE THERAPEUTIC AND PROPHYLACTIC REMEDIES
The objective of the present work was to study the influence of antiseptics contained in toothpastes on the microbiological and immunological status of healthy subjects who used the antiseptic toothpastes as therapeutic and prophylactic remedies. The evaluation of local immunity in the oral cavity included the elucidation of the effects of toothpaste triclosan and chlorhexidine on the oral cavity microbiocenosis. The duration of the safe use of antiseptic toothpastes was established taking into consideration potential changes in the “microflora-microorganisms” system under effect of antiseptic personal hygienic products.