EFFECTIVENESS OF CYCLOPHOSPHAMIDE IN TREATMENT OF STEROID-RESISTANT NEPHROTIC SYNDROME IN CHILDREN
Effectiveness of methylprednisolone and cyclophosphamide pulse therapy in children with steroid-resistant nephrotic syndrome (SRNS) were studied. This method was used to treat 34 children with SRNS. Among patients with primary nephrotic syndrome, there was a higher incidence of steroid-resistant nephrotic syndrome (27.8%). The use of methylprednisolone and cyclophosphamide pulse therapy has a positive effect in 47 % of patients with steroid-resistant nephrotic syndrome with morphological types such as minimal change disease and membranous nephritis. Revealed low efficiency of methylprednisolone and cyclophosphamide pulse therapy in the treatment of focal-segmental glomerulosclerosis in children.