PREOPERATIVE STRESS IN PATIENTS WITH ISCHEMIC HEART DISEASE
Purpose of the study: To evaluate the interconnection of stress induced disorders of homeostasis with the frequency of development of the perioperative complications of coronary bypass surgery. Information and methods: 97 patients with the ischemic heart disease were subjected to coronary bypass surgery, the analysis of clinical and chemical characteristics of preoperative stress has been conducted. Results: During the day before surgery, the patients with the ischemic heart disease had aggravation of the coronary insuffi ciency and the frequency of heart rhythm disturbance. Th e patients with the high stress activity in the preoperative period showed impairments of antioxidant system, violations of immune balance and hormonal status, as compared with the patients with stable preoperative period. Th e severity of preoperative stress caused the frequency of the development of intraoperative complications. Conclusion: Th e results obtained show that development of stress syndrome before operational intervention has the prognostic signifi cance for the intra- and postoperative periods, and indicates the necessity of individual approach to the choice of the optimal scheme of stress limiting preoperative preparation of the patients with the ischemic heart disease.