Management of Cell Immunity Parameters in Patients with Bladder Cancer After Radiotherapy
Today radiotherapy is one of the main methods for many malignant neoplasms therapy, including bladder cancer. The work purpose was assess the effect of radiotherapy on the cell immunity parameters in patients with bladder cancer, as well as changes in these parameters during the use of radioprotector - sodium deoxyribonucleate. A change in the cellular composition of peripheral blood lymphocytes subpopulations, caused by the carcinogenesis processes during the bladder cancer, was found. Tumor escaped from immunological supervision is accompanied by a decrease in the content of T- and B-lymphocytes, and cytotoxic cell populations. Radiotherapy increases immunodeficiency. After radioprotector added the cell immunity parameters restored, in particular the content of T- and B-lymphocytes, also stimulated nonspecific immunity.