MicroRNA-21. -210 - modern stress markers in pregnant women
Anxiety during pregnancy is associated with numerous adverse effects for both mother and fetus. The aim of this research is to study the potential role of miR-21 and miR-210 as markers of anxiety during pregnancy. There was studied the expression of the level of microRNA 21 and 210 in the whole blood of pregnant women with different level of anxiety. According to the results, the level of anxiety in pregnancy correlates with the level of microRNA 21 and 210. These micro RNAs are hypoxic, and they regulate the expression of genes that are involved in the development of essential obstetric pathology - preeclampsia and IUGR (intra-uterine growth retardation) of a fetus. They also provide all mechanisms of adaptation of organism. So, women with high level of anxiety are at high risk of obstetric and perinatal complications.