ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1: STRUCTURE, REGULATION, AND PARTICIPATION IN CELLULAR PROCESSES
This review summarizes available information about the structural organization and regulation of functional activity of adenylyl cyclase-associated protein 1 (CAP1) and its participation in cellular processes. There are numerous data on the role of CAP1 in the regulation of the actin cytoskeleton and its interactions with actin-binding proteins. Attention is drawn to the similarity of the structure of CAP1 and its contribution to the remodeling of actin filaments in prokaryotes and eukaryotes, and to the difference in the interaction of the protein with adenylyl cyclase in these cells. In addition, we discuss the participation of CAP1 in various pathological processes.