DEVELOPMENT OF METHODOLOGY FOR ANALYSIS OF ACTIVE SUBSTANCES IN SUPPOSITORIES "KLIMEDEX"
Methodologies for qualitative and quantitative determination of metronidazoleа, clindamycine phosphate, fluconazole, dexamethasone natrium phosphate, which are contained in vaginal suppositories «Climedex» by means of method of HPLC are offered. This method was chosen by us, as it is the most recently used method for qualitative and quantitative determination of multicompoponent medicines.As a result of experiment possibility of authentication and simultaneous quantitative determination of four active substances within the limits of one analysis at possible time and detection on two lengths of waves has been set.The offered methodology can be used for development of project of methologies of analysis of vaginal suppositories «Climedex» and reproduced in industrial conditions.