PROSPECTS FOR IMPLEMENTATION OF PERSONALIZED MEDICINE METHODS IN MEDICAL REHABILITATION AND SANATORIUM-RESORT TREATMENT OF PATIENTS WHO RECOVERED FROM COVID-19
The aim of the study is to assess the feasibility of implementing patient genotyping technologies to identify biomarkers of risk of post-covid complications that are appropriate for personalized prevention of thrombosis, endothelial dysfunction, non-drug treatment, and pharmacotherapy. Material and methods. On the basis of FSBI FSCC MR RS FMBA (at the end of August 2021), medical rehabilitation was carried out for 492 patients with complications after COVID-19; 51 (10.4%) patients were consulted by a geneticist to personalize management; 15 of them (29.4%) were genotyped (PCR-RT) on panels (SNP sets) of predisposition to multifactorial pathology and features of pharmacogenetics of drugs. Results. According to the identified risk alleles for the patient and the attending physician, genotyping data were interpreted with individualized recommendations for preventive therapeutic and preventive measures. Conclusion. The identified biomarkers can be used to target monitoring of the necessary biochemical and functional indicators, choosing more effective pharma therapy (adequate drug and dose), less risk of developing complications, undesirable drug reactions.