ERYTHROCYTE AND RETICULOCYTE INDICES IN PATIENTS WITH INFLAMMATORY DISEASES OF DIVERSE GENESIS
Use of the latest blood analyzers with a capacity of differentiated determination of reticulocyte and erythrocyte blood indices in modern diagnostic service is an important addition to detection of anemia syndrome. Generally used standard blood indices in form of a number of erythrocytes and hemoglobin level do not reflect pathophysiological changes leading to anemia development. Flow cytometry methods in modern blood analyzers favor a better evaluation of erythropoiesis by determining several reticulocyte parameters. These studies are important for detection of anemia, especially of anemia of chronic disease. As different mechanisms of pathological iron metabolism changes — deficiency, accessibility and reutilization derangement — may be observed at anemia syndrome, it is necessary to additionally determine the level of inflammatory markers in blood serum in order to choose a correct treatment tactics.