THROMBOCYTIC INDICES IN PATIENTS WITH ISCHEMIC HEART DISEASE
Objective. To determine the thrombocytic index (TI) values in patients with ischemic heart disease (IHD) various forms (atherosclerotic cardiosclerosis accompanied by cardiac rhythm disorders, stable and unstable stenocardia, myocardial infarction), how those values differ depending on the disease clinical form, the TI reciprocal correlations and correlations with a number of clinical and laboratory characteristics. Materials and methods. Two hundred and fourteen in-hospital patient's medical cards have been studies retrospectively. The patients' clinical characteristics (age, gender, height, weight, arterial pressure), blood counts and biochemical assay variables, lipidograms and coagulograms have been analyzed. Results. TI values have been determined for patients with the IHD various forms, statistically reliable differences have been registered for PLT (P=0.02), MPV (P<0.0001), PDW (P=0.01). Patients with the IHD acute forms have been determined to demonstrate higher PLT and PCT values the MPW and PDW values being lower. A moderate inverse correlation has been determined between the platelets number and size (r=-0.589, P<0.0001), a moderate direct correlation has been found between the platelet size and heterogeneity (r=0.643, P<0.0001) as well as between the TI value and a number of other laboratory variables in different groups of patients. Conclusion. Data evidencing that the TI values and their reciprocal correlations and correlations with some other laboratory variables differ depending on the IHD clinical form have been obtained. Further studying TI will allow determine whether those values can be used for specifying the diagnosis, determining the prognosis and the therapeutic tactics selection for IHD patients.