MECHANISMS OF INCREASING THE RESISTANCE OF TEETH PERIODONTIUM AND ENAMEL TO CHRONIC STRESS EXPOSURE BY MEANS OF IODINE-CONTAINING THYROID HORMONES
It is known that stress exposure is one of the most important systemic factors causing dental diseases development. At the same time iodine-containing thyroid hormones along with the sympatho-adrenal and the hypothalamicpituitary-adrenocortical systems hormones have been found to play an important role in an organism’s adaptation to acute stress exposure. However, up to now there are no researches concerning the mechanisms of increasing periodontium and tooth enamel stability to chronic stress exposure. In experiments on 684 adult male Vistar rats with the mass of 200-250g and on the basis of literature sources analysis mechanisms of increasing periodontium and tooth enamel stability to chronic stress exposure have been established: restriction of lipid peroxidation processes in periodontium (by stimulating the activity of antioxidant enzymes), the decrease of the intensity of the stress response, the improving of overall stability of the body, as well as proteinases / inhibitors balance normalization, stimulating influence of thyroid hormones on hemocirculation, the immune system, the secretory function of salivary glands and limitation of bone tissue resorption.