INFLUENCE OF THE TONUS OF SYMPATHO-ADRENAL AND HYPOTHALAMIC-PITUITARY-ADRENAL SYSTEM ON THE FUNCTION OF HEPATOGENIC ORGANS IN DOGS WITH DIFFERENT STRESS SENSIBILITY
The article examines the character of changes of the characteristic values of the hypothalamic-pituitary-adrenal system of working dogs with different levels of sensitivity to stress, as well as the influence of the hormonal state on the blood making organs function. The dogs’ sensitivity to stress was determined by the method of A.I. Kuznetsov,T.A. Vasilyeva [6]. The method is based on the principle of local adaptation syndrome (LAS). It is known that the features of the LAS progress, as a rule, correspond to the character of manifestation of the general adaptation syndrome [2, 3, 4, 5]. 50% turpentine in a dose of 0.05 ml was used as a dosed irritant, which was injected intradermally into the middle of the outer side of the auricle by a needleless injector (МБИ-1). Investigations were carried out on the basis of cynological service center of Kurgan Regional Office of the Ministry of Internal Affairs of Russia using the working dogs of German Shepherd breed aged 2-6 years. Two groups of animals were formed from among the dogs with known stress sensitivity by the principle of analogues: stress susceptible, stress resistant, there were 7 animals in each group. The nature of the hormonal changes in the organism in response to the activity of the dosed irritant was determined by the quantitative change of epinephrine, norepinephrine and the content of cortisol and corticosterone in the blood. To assess the work of blood making organs, a morphological examination of the blood was carried out simultaneously. Based on the results of the data obtained, it can be seen that the reaction of the blood making organs of the dogs with different stress sensitivity is not the same and depends on the level of changes in the hormones in blood after injection of the stressor. Stress susceptible animals have the high tension of the hypothalamic-pituitary-adrenal system, it leads to the changes in the morphological blood values that are specific to the alarm reaction. Changes appropriate to the stress-resistant state were observed in the group of stress resistant animals. The profile of changes for dogs with questionable sensitivity to stress had the features of stress sensitivity and stress-resistance.