Laboratory Study of Tear Fluid Based on the Use of a Standardized Technology for Its Collection and Sample Preparation: Results of Validation of the Method for Taking Biological Fluid
The presented method of collecting tear fluid for laboratory testing using Schirmer strips, compared with other methods of obtaining tears, is characterized by minimal trauma, safety and is feasible, including in patients with a pronounced deficiency of the aqueous part of the tear. This method is characterized by accessibility, is easily feasible, and expands the possibilities of conducting studies of tear fluid in patients with insufficient tear production. The purpose of the validation of the presented method of lacrimal fluid intake is a documented confirmation of the correctness of the choice of the method of biological fluid intake for a specific application in real conditions. As a result of the validation, irrefutable objective evidence was obtained that the requirements for using a specific method of collecting tear fluid for the purpose of laboratory testing were met. The test results obtained met the criteria of correctness, convergence and reproducibility.