Mechanisms of realization of the pathogenic potential of stress
On the basis of studies conducted in the Department of Physiology of visceral systems in the past 45 years, provided rationale for the concept of realization of the pathogenic potential of stress. In accordance with this, prevention of socially significant types of pathologies as hypertension and ulcerative lesions of the gastrointestinal tract is possible on the basis of correction of functional disorders in cardiovascular and digestive systems, caused by stress. Summarized the results of study of adrenergic influences on the smooth muscle of arterial and venous vessels and the gastro-intestinal tract, of the coordination of stimulatory and inhibitory mechanisms of the enteric nervous system during stress. Described possible mechanisms of realization of the pathogenic potential of stress: gastroduodenal motor discoordination, total increase of the colon tone in the poststress period and adrenergic constriction of venous sphincters in the combination with hightend pressure in organ veins.