POSSIBILITIES OF THE THERAPEUTIC INFLUENCE ON PATHOGENESE OF THE DEVELOPMENT OF DEFORMING OSTEOARTHRITIS
All the inflammatory diseases of joints and particularly deforming osteoarthrosis are the most frequent reasons of looking for medical service nowadays. It reduces the quality of life, leading to the following disability. This disease is really socially significant, cause it affects a large part of the working-age population and leads to the persistent pain syndrome with the development of synovitis. Also it's really important, that age of people suffering from this pathology is implacably getting younger. Pro-inflammatory cytokines and their imbalance with the anti-inflammatory ones play an important role in the pathogenesis of deforming osteoarthrosis. The study of cytokine connections and the developing imbalance in the content of pro- and anti-inflammatory interleukins, the analysis of correlations between changes in cytokine concentrations relative to each other, as well as in combination with the other factors is a promising direction of modern medicine in the treatment of patients with deforming osteoarthrosis. The development and improvement of non-pharmacological treatment methods, such as TES-therapy, will make it possible to change the approach to the treatment of deforming osteoarthrosis, cause it is possible to change the course of the disease and thereby increase the patient chances for recovery only by the making influence on the main link of pathogenesis.