Influence of surgical treatment under burn shock on the index of endogenous intoxication in injured in a methane explosion - coal mixture
The aim of this study - to study the effect of surgical treatment of burn shock stage on the dynamics of leukocyte index of intoxication in groups of fired miners, victims of the explosion of methane - coal mixture. The object of the study was the change of leukocyte index of intoxication for 10 days in groups of fired miners differing tactics of surgical treatment of burn shock stage. Patients of the main group (n=120) who were treated at the burns unit of the Institute of Urgent and Recovery Surgery in the period from 2004 to 2012, at the stage of burn shock was performed primary surgical treatment of burn wounds, superficial burns relevant, while closure of postoperative temporary biological surface coating (xenografts). Have affected the comparison group (n=80) were treated in the clinic between 1995 and 2003, such surgery in burn shock stage were not fulfilled. Groups comparable in size and the total destruction of deep burns, inhalation injury severity, the degree of carbon monoxide poisoning, and other features. Comparisons of the mean leukocyte index of intoxication Group held on 2nd, 4th, 7th and 10th days after injury in some subgroups, allocated according to the severity of burn shock, which specifies the index of severity. In the main group of patients with very heavy, heavy and severe burn shock at 4th, 7th and 10th days after injury revealed a statistically significant difference (p<0.05) compared with the average leukocyte intoxication index patients of the comparison group. The resulting dependence suggests that the primary surgical treatment of burn surface areas in a stage of shock reduces component of endogenous intoxication in the affected miners. The observed for 4 - 7 days after injury in patients of the main group decrease mortality by 3.5 times, it was due, in our opinion, surgical treatment of burn wounds in burn shock stage.