ВПЛИВ ДЕКСАМЕТАЗОНУ, ВВЕДЕНОГО ХРОНІЧНО, НА СТАН СИНАПТИЧНОЇ ПЕРЕДАЧІ В СКЕЛЕТНОМУ М’ЯЗІ БІЛИХ ЩУРІВ
In experiments on white rats it has been shown the phase character of change of the condition of synaptic transmission in the forward tibial muscle in dynamics of chronic injection of dexamethasone: after 5 injections of dexamethasone the latent period of muscle’s excitation has been shortened, whereas after 10 injections – has came back to control level, after 15–25 injections – has been extended, and after 30 injections of a hormone – has been again normalized. At the same time, reliability of a neuromuscular transmission has been decreased after 10 injections of dexamethasone and has been remained lowered on all extent of the period of its further injection in organism.