Cardiac Rhythm Disturbances: Therapeutic Options for Patients With Chronic Cor Pulmonale
We examined 68 patients with chronic obstructive pulmonary disease associated with chronic cor pulmonale. These subjects had changes in heart-rate variability and various cardiac rhythm disturbances suggestive of hyperactivity of the sympathoadrenal system. Added to a complex treatment protocol, Nebivolol helped treat patients' arrhythmias and improve the tone of the autonomic nervous system. Patients who received this selective β-adrenoblocker did not have any statistically significant changes in pulmonary function parameters.