Modern problems in the medical treatment of glaucoma
An analysis and prospects in development of modern medical treatment of patients with primary open-angle glaucoma (POAG) has been carried out. An integrative evaluation of the conformity of the hypotensive medication to the modern quality requirements of treatment has been developing at the present stage. Twenty eight patients with POAG (56 eyes) with different approaches of glaucoma therapy were enrolled in the study. The level of osmolarity of tear fl uid in all of patients was measured twice. Our results have shown a correlation between the level of intraocular pressure and osmolarity of the tear fluid (r=0.93, p<0.05). It is also found that the level of osmolarity tear fl uid was significantly lower and more decreased during treatment in patients who used preservative-free form of prostaglandin analogue, compared with medication which contained preservatives. The advantage of use of the preservative-free forms of antihypertensive drugs in glaucoma has been shown. The urgency of the problem, the main directions of development of modern medical treatment of glaucoma, necessity of the further development and research of new forms of the hypotensive medication according to the newest scientific achievements has been marked.