MORPHOFUNCTIONAL STATE OF BONE MARROW CELLS IN CONDITIONS OF VARIOUS DURATION OF THE ELECTROMAGNETIC FIELD OF THE WI-FI DEVICE
An assessment of the morphofunctional state of bone marrow cells (multipotent mesenchymal stromal cells - MMSC and hematopoietic stem cells - HSC) of male rats subjected to chronic exposure to the electromagnetic field (EMF) of a Wi-Fi device (2,45 GHz, PD = 0,01-1,56 pW/cm<sup>2</sup>, 24 h/day) starting from the age of 50 day age and before they reach 3 and 6 months was made. An increase in the number of apoptotic forms, the frequency of micronuclei and a decrease in the proliferative activity of the MMSCs in the young organism ware established, while a longer effect of the studied factor leads to an increase in cells in the synthetic phase. The most significant changes in the morphofunctional state of the HSCs are established with prolonged exposure, as indicates an increase in the share of cells with of single- and double-stranded DNA breaks with an increase in the number of cells in the synthetic phase. The revealed changes in the morphofunctional state of bone marrow stem cells indicates the sensitivity of multi- and polypotent cells (MMSCs and HSCs) on the long-term exposure to low-intensity electromagnetic field, which may affect their differential potential.