Pathogenetic role of changes in the type of blood circulation in the dynamics of brain vascular disorders
Features of the heart rate variability at patients with acute disorder of cerebral circulation depending on the type of hemodynamics were studied in acute period of disease and in a condition of relative functional rest. Surveyed men and women (121 patients, 30-55 years old) were divided into 3 groups according to the type of hemodynamics that was defined at the first day of their disease: the groups of patients with hyper-, hypo- and normodynamic types of hemodynamics were selected. The integral rheography of the body was carried out again on the 7th day of hospitalization of the patients. And according to the received data all examined individuals were divided into subgroups. The evaluation of indicators of the heart rate variability at patients during acute period of disease showed the significant increase of activity of the sympathetic link of regulation among people with hyperdynamic type of hemodynamics: the indices of tension and vegetative balance also as the standard deviation of NN intervals (SDNN) were rather law. The sam e patients examined on the 7th day of their disease demonstrated the reduction of the indices of tension and vegetative balance and the increase of the mean square difference between the duration of adjacent R-R intervals (RMSSD). These changes were regarded as gradual weakening of the sympathetic influences on cardio-vascular system in stabilization period. At examination of patients in a week from the moment of their hospitalization transformation of the type of hemodynamics was revealed among many of the surveyed. The indices of tension and vegetative balance were the lowest among patients with acute disorder of cerebral circulation and initially hyperdynamic type of hemodynamics and newly formed hypodynamic type of blood circulation. While patients with acute disorder of cerebral circulation and constantly hyperdynamic type of blood circulation showed the maximal tension in operation of the regulatory systems.