Using liposomes in the treatment of eye diseases. An experimental study. Part 1.
Clinical and morphological studies of biocompatibility of liposomes of different lipidic structure injected intravitreally were performed on animals (rabbits). Fluorescent microscopy was used to detect the penetration of liposomes into the internal granular layer of the retina. Accumulation of Dexamethasone (DM) and Dexamethasone Phosphate (DMF) in liposomes was analyzed. The studies confirmed that intravitreal introduction of Dipalmitoylphosphatidylcholine liposomes laden with DM is safe. // Russian Ophthalmological Journal, 2012; 2:82-87.