Level of maxillae alveolar bone loss after implantation ceramic hydroxylapatite OC-015 into the tibia
Aim of the study is to investigate dynamic changes of maxillary alveolar bone loss after implantation ceramic hydroxylapatite OC-015 into the tibia. Material and methods. 90 male rats with body weight of 190-225 g were used. Animals were distributed into three groups. Group 1 consisted of the controls. Group 2 - the animals with tibia fracture modeled as 2 mm round opening in the tibia. In animals of the group 3 the same 2 mm opening was filled with hydroxylapatite material OC-015. Measurements were performed on the buccal and the palatal surfaces. Results. In group 2 the buccal cemental-alveolar junction/alveolar bone crest distance (CEJ-ABC) exceeded that of the group 1 by 6.23%, 9.59%, 10.54%, and 5.16% in the period from the 15<sup>th</sup> to the 90<sup>th</sup> day and the palatal CEJ- ABC - by 5.80%, 6.21%, 12.17%, 9.72%, and 6.60% in the period from the 7<sup>th</sup> to the 90<sup>th</sup> day. The area of bone loss on the buccal side was wider than that of the group1 by 4.69%, 8.65%, 9.67%, 10.01%, and 6.01% in the period from the 7<sup>th</sup> to the 90<sup>th</sup> day, and on the palatal side - by 6.85%, 8.99%, 10.12%, 9.89%, and 5.58%. In group 3 the buccal and the palatal CEJ-ABC in comparison with the group 2 increased by 5.81% and 4.79% and the palatal area of bone loss - by 4,63% (all on the 15<sup>th</sup> day). The buccal area of bone loss was wider than that of the group 2 by 4.42% and 7.58% on the 7<sup>th</sup> and the 15<sup>th</sup> days. In the period from the 30<sup>th</sup> to the 90<sup>th</sup> day the palatal CEJ-ABC was shorter than that of the group 2 by 5.07%, 5.28% and 6.06%, a the buccal CEJ-ABC by the 60<sup>th</sup> day - by 4.71%. The palatal area by the 60<sup>th</sup> and the 90<sup>th</sup> day narrowed by 4.24% and 5.18%, and the buccal area by the 90<sup>th</sup> day - by 4.28%. Conclusion. Implantation of OK-015 into the tibia reduces adverse effects of intervention on maxillae alveolar bone beginning from the 30<sup>th</sup> day after surgery.