Shifts in the structure of the hierarchical system of homeokinesis in CHD patients against the background of stress exposure
The article presents the data on the possibility of obtaining additional diagnostic information about the reactions of the systemic regulation of the body under stressful conditions implemented as a part of the stress-test in patients with coronary artery disease: stable exertional angina. The implementation of an alternative approach to the assessment of adaptation processes arising against the background of measured physical activity is based on the assessment of the shifts in the topology of the entropic attractor model of the sinus heart rate reflecting the phenomenon of systemic homeokinesis. Against the background of the transition process in systemic regulation during stress-test, at the attractor structure has been revealed the development of the heart rate entropy, being a complex object, with the effects of activation and consolidation of its levels, which are significantly more pronounced during the formation of myocardial ischemia. The proposed digital indicators reflecting the identified topological changes can be used for an objective quantitative diagnosis of the phenomenon of destabilization of the systemic body resistance during the exacerbation of acute somatic pathology.