Effect of different doses of coordination compound of germanium with nicotinic acid on oxidative modification of heart proteins in rats with chronic doxorubicin intoxication
The purpose of the study was to investigate the effect of different doses of coordination compound of germanium with nicotinic acid (MIGU-1) on the peroxidation of proteins in conditions of chronic intoxication with doxorubicin. It is proved that the use of MIGU-1 daily prevents the progress of protein peroxidation in cardiomyocytes, which allows us to consider MIGU-1 as a drug with a possible cytoprotective activity, and its further investigation may be considered as current and prospective.