ROLE OF GENE POLYMORPHISM AGTT174M AND M235T IN ATRIAL FIBRILLATION IN THE KRASNOYARSK
By results of work there was an inspection of 90 probands with the confirmed diagnosis atrial fibrillation, and also 144 of their relatives of I, II, III degrees of relationship. These families have made the main group of our research. The group of control has been created from rather healthy people without cardiovascular pathology in the anamnesis. This group was made by 100 peoples.To all patients the following methods examinations have been conducted: collecting anamnesis and complaints, electrocardiogram (ECG), ekhokardioskopiya (EHO-KS), Holter monitoring of the ECG, transesophageal stimulation of the left atrium, molecular and genetic analysis, to all patients the having AF has conducted a research of hormones of a thyroid gland. By results of a research statistically significant results haven't been revealed interrelations of Т174М and M235T of polymorphism of a gene of AGT with development of AF in one subgroup of patients. The received results can be defined first of all by genetic features of the population of the Siberian region, which depend on climatic and geographical conditions, and finally confirms that AF is a heterogeneous disease.