EVALUATION OF THE ACTIVITY OF THE CHEMOTHERAPY DEPARTMENT REGIONAL STATE BUDGETARY HEALTH INSTITUTION "SMOLENSK REGIONAL CLINICAL HOSPITAL"
Objective. To evaluate the results of treatment of patients in the chemotherapy department of the Regional State Budgetary Health Institution "Smolensk Regional Clinical Hospital" in 2020 and 2021. Methods. Based on the data of the territorial cancer registry of the regional state budgetary healthcare institution "Smolensk Regional Oncological Clinical Dispensary" (OGBUZ SOOKD), the official accounting and reporting medical documentation of patients with a morphologically confirmed diagnosis of cancer who received inpatient treatment in 2020-2021 was studied. in OGBUZ SOKB in the form of neoadjuvant, adjuvant and independent chemotherapy. Case histories, statistical coupons and outpatient cards of patients were analyzed. Statistical processing of the results included methods of descriptive statistics and was carried out using MS Excel 10. Results. Total number of patients treated with chemotherapy in 2020 there were 663 people (48.9%), in 2021. 692 people (51.1%). There were 433 (31.95%) patients with tumors of the head and neck, 390 (28.7%) of the respiratory organs, and 170 (12.55%) of the female genital organs. These patients received self-administered (curative) chemotherapy in 48.1%, maintenance chemotherapy regimens were used in 31.9%, and adjuvant chemotherapy was performed in 13.5%. Neoadjuvant chemotherapy was performed in 6.5% of cases. Due to the fact that the stage of malignant neoplasm in 84.37% of patients referred for treatment to the chemotherapy department was neglected, the complete response to chemotherapy did not exceed 2.1%, stabilization of the process was recorded in 38.4%, and a partial response in 23.6% of cases. Disease progression was recorded in 19% of patients. Conclusion. The results of chemotherapy performed on patients with tumors of the female genital organs and respiratory organs are comparable with the results of chemotherapy performed in other territories. The effectiveness of chemotherapy in patients with head and neck tumors is low, due to the admission of patients with advanced stages of cancer and without surgical intervention, which is why the share of self-chemotherapy was 48.1%. To improve the results of work, it is necessary to intensify work on the surgical treatment of oral cancer.