Functional gastrointestinal disorders in children with atopic dermatitis
Recent studies have demonstrated the high prevalence of gastrointestinal disorders (GID) among children with atopic dermatitis. The aim of this study was to evaluate mechanisms of functional GID in children with atopic dermatitis with a view to enhancing the efficacy of disease management. The methods employed included clinical examination of children with atopic dermatitis aged 4 to 16 years, using SCORAD index for clinical evaluation of disease activity, electrogastroenterography to assess patients' gastrointestinal motility and clinical assessment of the vegetative state. Our study demonstrated the pathogenic link between GID, atopic dermatitis activity and neurological disorders. GI tract dysmotilities appear to be linked to the state of the autonomic nervous system and adaptation mechanisms and influence the course of the underlying disease and thus require corrective action as part of comprehensive therapy