Assessment of adequacy parameters of the inflammatory response in children with severe forms of suppurative surgical infection
Correct evaluation of an intense and acute inflammatory process is essential for the successful treatment of children with severe surgical suppurative infection and adequate correction of concomitant changes. We studied the relationship between activity of the inflammatory process in children with acute hematogenous osteomyelitis, acute pyodestructive pneumonia and selected clinical and laboratory characteristics. Parameters of the adequate inflammatory response (PAIR) corresponded to the optimal variant of the inflammatory process, i.e. normoergic inflammatory reaction. Comparison of these data with PAIR values allow for quantitative assessment of the inflammatory reaction, its adequate medicamental correction (activation of hypoergic reaction and suppression of hyperergic one), and substantiation of surgical strategy.