Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
Isolated left ventricular noncompaction (LVNC) in adult patients is a rare form of primary cardiomyopathy. There have been several morphological studies of this condition in which a heart transplantation was performed. Objective: to analyze literature and clinical cases of patients with LVNC, macroscopic and histological data of the removed hearts. Materials and methods. At our center three patients (2 women aged 18 and 31, and 1 man aged 49) were morphologically diagnosed with LVNC had a heart transplant. We retrospectively analyzed the clinical, macroscopic and histological data of the removed hearts in these patients and the results of the transplants performed. Light microscopy of a fixed myocardial preparation stained with hematoxylin and eosin was used for histological examination. Results. A histological examination confirmed the presence of LVMI in these patients. Conclusion. LVMI is a rare disease, that can occur asymptomatic or cause severe congestive heart failure, requiring transplantation.