ANALYSIS OF EXPRESSION MARKERS OF PROLIFERATION KI67 IN BENIGNE BREST TUMORS IN RELATION TO SEVERITY OF INFLAMMATORY REACTIONS IN ITS TISSUES
Based on the analysis of the expression of total leukocyte antigen CD45 in trephine - biopsies of benign breast tumors in 38 patients of reproductive age allocated 2 clinical groups: group 1 (n=23) - benign breast tumors with inammation (expression CD45+ cells (134.3± 8.4)%), group 2 (n=15) - benign breast tumors without inammatory response in tissues (expression of positive CD45+ cells (9,5 ± 1,5)%). On the background of high expression of the common leukocyte antigen CD45 noted an increase in the proliferative activity of the epithelium - proliferation index Ki-67 growth to the level (24,6 ± 1,6)% of positive cells, which is 3.3 times higher than its value in the tissues of benign breast tumors with low inammatory response.