Genodiagnostics of papilloviral infection of women with different pathology of reproductive system.
The goal of the research is to evaluate the frequency of disclosure by different genotypes of human papilloma virus of high carcinogenic risk, viral load among women of various ages with inflammatory infectious processes of the reproductive system and neck of uterus diseases. The research material was patterns of cervical canal. The human papilloma virus were revealed among 1128 patients (84,4%); the negative results were revealed among 208 people (15,6%). Clinically less significant virus concentration was observed among 640 patients (47,9%), i.e. nearly half of examined women. Clinically significant human papilloma viruses concentration was registered among 436 patients (32,6%), increased concentration - among 260 women (19,5%). The viral load was appraised in different age groups - 555 patients in all. Clinically less significant viral load frequently occurred among elder people (more than 51 age old), it was registered among 53,8% patients. Genotype determination of human papilloma virus was conducted among 2665 people. 304 humans (11,4%) had a negative viral analysis test done; virus was revealed among 73 humans (2,7%), however, genotype did not determine. The most widely distributed genotypes were 56, 16 and 51. Genotype 56 was detected among 729 humans (27,4%), genotype 16 - among 342 humans (12,8%), genotype 51 - among 294 humans (11,0%). The frequency of other genotypes detection varied from 1,6% to 6,8%.