RADIATION-INDUCED PERICARDITIS AFTER DIAGNOSTIC RADIATION EXPOSURE
Radiation therapy is a very important part of combine therapy for many cancers, improving survival, but also have well-known side effects. Aim. We present a clinical case of radiation-induced heart disease - exudative pericarditis after diagnostic radiation exposure. Material and methods. The article discusses the development of acute pericarditis in a patient underwent surgery for ovarian cancer stage 3, clinical group 2, T3 N0 M0. Results and discussion. After the surgery, the patient received 6 courses of chemotherapy with carboplatin 600 mg, paclitaxel 300 mg during the maintenance therapy: chloropyramine, latran, dexamethasone, quamel. In order to search for possible metastases for 6 months, the patient underwent 3 spiral chest computed tomographies (CT), 2 spiral abdominal and pelvical CTs, and whole-body position-emission computed tomography (PET-CT). The total radiation exposure was 75,9 mSv. Hypothyroidism, systemic diseases, nephrotic syndrome were excluded with the help of additional studies. This allowed us to suggest radiation genesis of pericardial effusion. As a result of treatment with ibuprofen 600 mg every 8 hours with colchicine at a dose of 0,5 mg 2 times a day with a 20 mg of pantoprazole once daily after 1 month of treatment, exudative pericarditis resolved. Conclusion. It is necessary to evaluate the total dose of radiation received earlier to prevent radiation-induced damage. It is necessary to use the most informative research methods to avoid repeated spiral CT.