The acute-phase proteins and macroglobulins in inflammatory processes of organs pelvic in women
The authors carried out a comparative study of the levels of immunoglobulins A, M, and G, concentrations of acute-phase -1-antitrypsin (AT), and also levels of lactoferrin (LF), -2-macroglobulin (MG) and pregnancy-associated -2- glycoprotein (PAG), that possess both the properties of acute-phase proteins, and the immunoregulatory properties, in blood serum of patients with different variants of inflammatory processes of the genital organs in order to specify pathogenesis and to evaluate the efficacy of the indices under study for making a differential diagnosis of diseases. It was found that concentrations of all the indices, except AT, changed. While for LF, an increase of its level of various degrees was observed in all groups, in case of MG these changes may take various directions depending on the severity and spreading the process, and the PAG level decreased only in disseminated destructive process.