PROGNOSIS OF NEUROLOGICAL SYMPTOMATOLOGY PRESERVATION BY THE END OF THE FIRST YEAR OF LIFE IN NEWBORN BABIES, WHO HAD CYTOMEGALOVIRUS INFECTION
Follow-up clinical and immunological studies were undertaken to examine the CD28+ T-lymphocyte, CD40+ B-lymphocyte response in the sera of neonatal infants with cytomegalovirus infection. The pathogenetic role of anti-infective protection was established. The significant decrease in the levels of CD20 <sup>+</sup>CD40 <sup>+</sup> and lowering CD3 <sup>+</sup>CD20 <sup>+</sup> was found to be a prognostically poor determinant serios cytomegalovirus virus infection. It was revealed that for the preservation of neurological symptoms by the end of the first year of life it is statistically significant to determine in peripheral blood functional activity of CD3, CD4, CD40T-lympho-cytes, lymphocytes expressing CD28, CD3 <sup>-</sup>CD28+ in the total population, T-lymphocytes without CD28 (CD3+CD28 <sup>-</sup>) costimulation marker and also T-lymphocytes expressing CD71+, CD95+ markers of late activation on their surface.