REGENERATIVE ACTIVITY OF THE TRACHEAL EPITHELIUM IN THE APPLICATION OF DIHYDROQUERCETIN ON THE BACKGROUND OF GENERAL COOLING OF ANIMALS OF DIFFERENT AGE GROUPS
To assess the regenerative potential of the epithelium of the mucous membrane of the trachea, a morphological marker - alkaline phosphomonoesterase was used, the intensity of the reaction of which reflects the functional activity of basal (stem) cells. With the general cooling of the body, the lowest reaction was observed in the group of animals aged 19-20 months (old). In rats of this group, the number, area and size of the nucleus of basal cells decreased. The use of dihydroquercetin against the background of general cooling led to a moderate increase in the reaction to alkaline phosphomonoesterase in old animals, the morphometric indices basal cells increased slightly in comparison with animals at the age of 6-7 months