Dynamics of clinical picture, morphofunctional parameters of myocardium and adherence to treatment at conservative and surgical treatment of chronic ischemic heart disease
The aim of this study was to compare the dynamics of the clinical picture, morphofunctional parameters of the myocardium and adherence to treatment against the background of optimal medical therapy (OMT), including drugs that improve the prognosis, and percutaneous coronary intervention (PCI) in combination with OMT in patients with stable coronary heart disease during prospective observation. The study included 125 men aged 50-75 years. The main group (PCI with stenting + OMT) consisted of 78 people aged 61.5 ± 8.5 years; the comparison group (OMT) consisted of 47 people aged 63.5 ± 7.1 years. By age and frequency of the main cardiovascular risk factors patients did not differ significantly. Patients of both groups with a frequency of more than 90% had arterial hypertension (AH) with a history of 10.3 ± 2.5 years. Also patients of both groups did not differ significantly in functional class of angina pectoris, duration of ischemic history, frequency of myocardial infarction and functional class of chronic heart failure. After a year of observation there were no significant differences in the dynamics of morphometric and functional parameters of myocardium in both groups against the background of the treatment. The main reason for low treatment adherence was the lack of understanding of the need for taking medications (primarily statins) with good health.