Inhalation drug delivery devices in pulmonology
Information on modern types of inhalation devices for drug delivery in pulmonology is given. It is shown that pulmonology uses a wide arsenal of inhalation delivery devices, which have been used for a long time both for emergency treatment and for basis inhalation therapy. Now time inhalations of bronchodilators, glucocorticosteroids, antibacterial and mucolytic drugs are used. Different properties of medicinal substances dictate the need to optimize the methods of their delivery. All delivery devices have positive and negative characteristics. At the same time, there is currently no ideal devices for drug delivery. Ideal delivery devices should possess portability, speed and convenience of use, no complications in application, low oropharyngeal and high pulmonary deposition, high efficiency, no side effects, low cost. The physicochemical properties of the drugs used are also considered. In general, the current trend in modern medicine is the “targeted” delivery of the drug substance to the pathological focus, the creation of high drug deposits, the reduction of negative effects on the organism, which determines not only the therapeutic efficacy index (desired / undesirable effects) and the safety of the drug, but also patient’s compliance.