CHORIONIC GONADOTROPIN EFFECT ON THE STRUCTURES OF THYMUS EXSPRESSING CD8
In experiments on 40 mice-females changes CD8-positive structures in the thymus after intramuscular introduction of human chorionic gonadotropin (HCG) (0,02 ml) for 1, 2, 3, 4 weeks were studied. An increase in the number of CD8-positive cells and cortical brain chemicals segments of the thymus in a week were revealed. In corticomedullary zone the number of CD8-positive cells is reduced. In the subsequent timing of the introduction of HCG in all the surveyed areas of thymus the number of CD8-positive cells still tends to increase in comparison with the intact group. Morphometric analysis of CD8-positive cells of the thymus the infusion of HCG showed an increase in the area of the investigated cells in comparison with the intact animals (in intact animals 91,12 ± 12,00 mkm2; after 1 week of introducing CG – 103,35 ± 18,61 mkm2; after 3 weeks – 127,28 ± 17,08 mkm2; 4 weeks – 191 ± 15,34 mkm2).