TALERIN EFFECT ON CONCENTRATION OF FREE AMINO ACIDS AND BIOGENIC AMINES IN ANIMAL TISSUES IN CHRONIC INTOXICATION WITH DINYL
The disturbances of the metabolism of amino acids and biogenic amines in the organism of rats in chronic intoxication with dinyl and the possibility of stimulation of the adaptive mechanisms by introduction of talerin have been investigated. The chronic intoxication with dinyl is characterized by prevalence of processes of CNS inhibition and produces the disorganization of metabolic processes with prevalence of the catabolic component. This component is registered as an integrated increase of the concentration of free amino acids and their derivatives in plasma. The course application of talerin in conditions of chronic introduction of dinyl influences the metabolism both in the peripheral tissues and in cells of the central nervous system. The normalization of the metabolism of neuroactive amino acids and their derivatives, optimization of processes of biosynthesis of protein and phospholipids are an important moment in the effects of talerin. The effect of talerin is protective.