PHARMACOEPIDEMIOLOGICAL STUDY OF THE DYNAMICS OF CONSUMPTION OF ANTIHISTAMINES IN UKRAINE
According to the WHO, now allergy takes the 3rd place by the morbidity rate among other nosologies. According to statis- tics, 20-40% of the world population suffers from one or the other form of allergic diseases, and in Ukraine approximately 1.5% of the population has been diagnosed with allergy. However, the actual figures are much higher - up to 25% (about 10 million people). The aim of this study was to determine dynamics of AH consumption in Ukraine for three years and conduct the analysis of AH at the market for 2012 - 2014, as well as analysis of availability of drugs included into the standard of allergic rhinitis treatment, in the National Drug Formulary. The data from the National Drug Formulary of Ukraine (the 6th edition) and from the Appendix to the Order of the Ministry of Public Health No. 507 dated 28-12-2002 “Standards of medical care in allergic rhinitis” were used to determine availability of drugs included into the standard of AR treatment. The ATC/DDD methodology and data on the volume of AH consumption of Morion research and retrieval system “Medicines” were used to determine the volume of AH consumption. Currently, 14 INN AH, on the basis of which 164 drugs are proposed by TN, are presented in Ukraine. As of the end of 2014, Loratadine (2.62) > Levocetirizine (1.91)> Cetirizine (1.78) > Mebhydrolin (1.38) became the leading medicines among AH by the volume of consumption in the DDDs/1000/d indicator. The medicines included into the Appendix to the Order of the Ministry of Public Health No. 507 dated 28-12-2002 do not comply with current standards of treatment according to the guidelines of the World Allergy Or- ganization; it indicates the preconditions of change in the Ukrainian recommendations for AR treatment in the near future.