New Diaryl(Heteroaryl)ethylphosphonic Asids
An original, new method for the synthesis of previously unknown diaryl(heteroaryl)ethylphosphonic acids containing pharmacophoric fragments was developed as a result of the acid-catalyzed reaction of (2-ethoxyvinyl)- phosphonic dichloride with heterocyclic compounds such as 4-hydroxy-6-methyl-2-pyrone, 4-hydroxycoumarin, and also thymol and carvacrol containing a hydroxyl group. Composition and structure of all diaryl(heteroaryl)- ethylphosphonic acids were confirmed according to <sup>1</sup>H, <sup>13</sup>С and <sup>31</sup>P NMR, IR spectroscopy, mass spectrometry and elemental analysis.