Influence of artificial carbon nanotubes on expression of Rb gene and viability of lymphocytes
Nanotechnologies that received the development last decades are the most perapective field of modem engineering and medicine. Alongside with the strong advantages nanoparticles can гendeг negative influence on living cells and organisms. In connection with increasing use of nanotechnologies there is the necessity of studying the potential toxicity related to influence of nanoparticles. The changes in expression of Rb gene of human lymphocytes after short-tem action of multiwalled carton nanotubes at 100 pg/ml concentration was investigated to assess the potential risks of using the artificial nanotubes, and also the vitality of blood lymphocytes after then incubation with artificial nanotubes. The increase in the expression of Rb gene in time-dependent manner and the influence of nanoparticles on sumival rate of lymphocytes in comparison with control samples were shown.