The changes of the activity of angiogenic factors after phacoemulsification of patients with diabetes mellitus and hypertonic disease
In recent years in clinical practice attaches great importance to factor ophthalmopathology comorbidity. This thesis maintains its significance in diabetic retinopathy combined with hypertension. Assessment of the impact of antihypertensive drugs on the balance of cytokines and angiogenic changes after phacoemulsification in patients of comorbid group allowed to establish a beneficial effect of ACE inhibitors on the stability of the angiogenic potential. It can be assumed that the basis of the described picture pharmaceutics are properties of ACE inhibitors, positively affecting the stabilization and reduction of endothelial dysfunction. Also on the basis of clinical and laboratory research was awarded the pathophysiological link between the level of VEGF and PEDF in the progression of diabetic retinopathy after phacoemulsification.