Prognostic factors of patients with gliomas: symptomatic-syndrome analysis
The research is directed toward understanding prognoses factors of patients with gliomas not considering their malignancy grade. It was analyzed prognoses factors of 280 patients, who underwent treatment in neurosurgery clinic of Military Medical Academy of S.M. Kirov from 1998 until 2008. 29 variables, that preoperational patient status, tumor qualities, and conducted treatment were studied. Analysis was made using Cocks model and symptomatic-syndrome method of structuralizing category data. Most significant prognostic factors were clinical symptoms: seizures, headache, disturbance of speech and consciousness. Conducted analysis helped to form four patient groups similar in clinical picture and without glioma histological type consideration, with significant difference in survival rates. Survival median varied from 27 to 79,4 weeks. Smallest survival rate was noted in patients over 60 y.o. with disturbance of speech, and had no correlation with the size of tumor. The largest survival rate was in patients with seizures and close to 40 y.o. Usage of symptomatic-syndrome analysis method helped us to estimate prognostic values of neurological symptoms in patients with glial tumors.