Brown tumors and osteopenia of uremic patients (literature review and clinical reports)
The article is devoted to one of the most serious skeletal complication of the secondary hyperparathyroidism - brown tumors. Due to the increase of survival of patients with chronic kidney disease, the reports on clinical cases of brown tumors in patients treated with dialysis or renal transplantation have been increased. In this review pathophysiology, clinical manifestations of brown tumors and diagnostic methods are considered. Two different cases of patients with brown tumors, severe osteoporosis and its successful management are described. Parathyroidectomy is a treatment of the first choice for the patients with diagnosed brown tumor. However, the alternative methods of therapy of this hyperparathyroidism complication are also discussed.