Magnet-resonance diffuse-weighted images in prostatic cancer
Purpose: to evaluate diagnostic possibilities of diffuse-weighed images for diagnosing cancer of the prostatic gland. Materials and methods: 40 men (average age 64±10,3 лет) with clinical manifestations of prostatic cancer have been examined with a high-field (1,5 Tl) tomograph. A technique for obtaining diffuse-weighed images of the prostatic gland has been used (gradient factors 0, 50, 300, 500, 800, 1000, 1400 s/mm2). 100% patients had puncture biopsy. Cancer was revealed in 32 (80%) patients. Results: The examination performed has shown that localized cancer was met in 68,8% (20 patients), locally spread cancer - in 31,2% (12 patients). The measured coefficient of diffusion in prostatic gland tumours was 56±23 х10<sup>-5</sup> mm<sup>2</sup>/s, in unchanged peripheric zones - 112±28 х10<sup>-5</sup> mm<sup>2</sup>/s, in areas of peripheric inflammation - 102±34 х10<sup>-5</sup> mm<sup>2</sup>/s, in hy-perplasia areas (central part) it varied from 70 till 183 х10<sup>-5</sup> mm<sup>2</sup>/s. The technique of diffuse-weighed images has increased sensitivity of primary cancer diagnostics comparing to native MRI scanning by 8,7% (up to 90,6%), specificity - by 25,0% (up to 75,0%). Conclusion: The technique of diffuse-weighed images is an additional effective approach for primary diagnostics of localized forms of prostatic cancer.