Values of thrombodynamics test and D-dimer level in pregnant women with aggravated obstetric history
The balance between the various links of hemostasis is formed during physiological pregnancy that prevents the development of thrombohemorrhagic events. The balance upset can lead to complications of pregnancy (miscarriage, threatened miscarriage, missed abortion, gestosis and others). The tests of D-dimer and trombodinamics were used in order to assess the hemostatis system in pregnant women with aggravated obstetric history at different stages of gestation. Trombodinamics is global test that visualizes the clotting process. It is as highly-sensitive both to procoagulant and to hypocoagulant changes in blood coagulation system. The growth of D-dimer levels depending on gestational age was revealed. Thrombodynamics test indicators were within the reference values for pregnant women. Such indicator as blood clot density (D) significantly increased with gestational age. Correlation analysis showed no relationship between values of trombodinamics test and D-dimer levels.