Experimental confirmation of the efficiency of bioactive implants calcium-phosphate coating in operations proven impact on bone regeneration in periimplantatsionnoy zone
Purpose of the study: was experimental evidence of the influence of bioactive implants with calcium phosphate coating on the regeneration of bone tissue. Materials and methods. Conducted an experimental study in rabbits breed «Sovetskaya chinchilla». The iliac bones of rabbits on both sides to establish various types of implants made of porous NiTi: on the left side of the implant was placed NiTi without calcium phosphate coating, and the right side - a bioactive calcium phosphate coating. The research included conducting a macroscopic, histological and radiological assessments of areas mentioned above implanting implants in terms of 7, 14, 28 and 36 days. A total of 16 animals were operated. Results. On day 7 of the experiment on the part of established bioactive implant with calcium phosphate coating coarse fiber beams marked the development of bone tissue. At a later date (14, 28 and 36 days) the area of coarse fiber bone increases bone shaped beams, osteoblasts differentiate into osteocytes. On day 28 marked individual osteoclasts. Conclusions. Experiments have shown the presence of bioactive implants with calcium phosphate coating expressed osteoinductive and osteoconductive properties.