The innovative technology of the operative treatment of the newborn hemolytic disease
The purpose of the study included the development and introduction of innovative technology operative treatment of the newborn hemolytic disease, using the umbilical vein and artery during blood exchange transfusion and intraoperative monitoring of the basic organism functions, including the state of regional oxygenation. Were comprehensively examined 4 newborns with hemolytic disease, who has undergone blood exchange transfusion. It was found that cerebral oxygenation improved by the end of the exchange transfusion from 65.5 [45,5-74,0] to 72.5 [59,5-81,0]. Visceral oximetry didn’t change significantly 39 [30,5-50,5] vs 39.5 [19,0-60,0]. No reduction in cerebro-splanchnic oxygenation ratio, as well as minor intraoperative changes of visceral oxygenation may indicate a lack of disturbances of microcirculation and tissue perfusion of the abdominal region during blood exchange transfusion, using the two-way exchange transfusion method, as well as maintaining stable blood pressure and cerebral oxygenation. Intraoperative monitoring of regional oximetry with registration of cerebro-splanchnic oxygenation ratio allows early diagnosing the disorders of microcirculation and tissue perfusion in the abdominal area.