THE SIGNIFICANCE OF THE FACTORS OF NONSPECIFIC IMMUNITY LBP AND SCD14 AT CIRRHOSIS OF THE LIVER
In 120 patients with cirrhosis of the liver, conducted a study of the blood on the content of protein connecting lipopolysaccharide and soluble cluster of differentiation. Changes of these indicators varies in wide range and may increase in patients with cirrhosis of the liver in average 3–5 times. The level of inherent immunity factors in general exceeds the normal values of 88 % and 87 % of patients studied, and its content in the blood depends on the activity of hepatic process, the severity of hepatocellular insufficiency and manifestations of portal hypertension. The presence of ascites and esophageal varices III-IV century largely influenced the content of the studied indexes, which was probably related to the presence of an extensive network of рorto-cavernous anastomoses, and the dumping of blood them into the blood endotoxin stream with the stimulation of endotoxin immunity.