The renal artery resistive index is an integral marker of renal dysfunction in patients with chronic heart failure
Objective: to study renal hemodynamic disorders in patients with Functional Classes (FC) II-IV chronic heart failure (CHF), by estimating the peripheral renal artery resistive index (RI), to reveal relationships to other hemodynamic parameters and mark­ers of chronic kidney diseases and with the presence of infectious, inflammatory, and metabolic renal comorbidity in the patient. Subjects and methods. Sixty-eight patients with FC II-IV CHF were examined. Renal hemodynamics was studied using renal artery duplex scanning; cardiac morphofunctional parame­ters were explored by echocardiography (EchoCG). The markers of renal lesion were examined using laboratory tests and the Cockcroft-Gault and abridged Modification of Diet in Renal Disease 1 (MDRD1) formulas for estimating the glomerular fil­tration rate. Results. The patients with FC II-IV CHF were noted to have renal blood flow disorder that was progressive with higher FC CHF. Tubulointerstitial renal comorbidity in patients with CHF has a statistically significant impact both on the degree of pro-teinuria, the reduction of renal filtration function, and the param­eters of distal renal blood flow. RI showed a stronger correlation with the degree of renal dysfunction and the markers of endothe-lial dysfunction than with the parameters of central hemodyna-mics and EchoCG.