ExOGENIC PHOSPHOCREATINE INFLUENCE ON RABBIT'S MYOMETRIUM CREATINEkINASE/ PHOSPHOkREATINE (CC/PC) SYSTEM AT THE END OF PREGNANCY
Exogenic phosphocreatine influence on the rabbit's myometrium creatinekinase/phosphocreatine (CC/ PC) system at the end of pregnancy was investigated. It was shown that myometrium CC/PC system condition was closely connected and, consequently, depended on contractile activity presence or absence. This system characterized a myometrium functional condition and its readiness for contraction. Under neoton influence changes in rabbit's myometrium CC/PC system had dose dependent character. The increase of exogenic phosphocreatine dose led to more strong suppression of мCC activity, increasing of free and total creatine. However significant differecies of PC level was not revealed. It was supposed that neoton introduction at the 30th day of rabbit's pregnancy promoted endocellular ADP rephosphorylation. 0,5 g dose neoton application contributed conditions at which not only moderate activation of myometrium contractions, but also their regulations were observed.