ASPECTS OF THE POSTOPERATIVE PERIOD PHARMACEUTICAL PROVIDING IN PATIENTS WITH LUNG CANCER, ESOPHAGEAL CANCER AND MEDIASTINUM ORGANS CANCER AFTER THE RADICAL OPERATIONS
The aim of the presented article is to summarize the experience and to analyze the results of the work carried out by the team of the Vitebsk Regional Clinical Oncologic Hospital to minimize postoperative mortality in patients from pneumonia after radical operations due to thoracic tumors. A retrospective analysis of the case histories of patients of the oncologic thoracic department for 2015-2016 and 2017-2018 was carried out. All postoperative pneumonia is divided into groups depending on the location, prevalence and severity of pneumonia. In each group, a specific antibiotic therapy algorithm was applied, taking into account measures to overcome antibiotic resistance. The article presents the antibiotic regimens with the use of broad-spectrum antibiotics of representatives of various classes of antimicrobial agents (2-4 generation cephalosporins, protected cephalosporins, fluoroquinolones, aminoglycosides, oxazolidinones, glycopeptides). It has been shown that their use is effective in patients with pneumonia after radical operations regarding thoracic tumors. A set of measures for the prevention and treatment of pneumonia in this category of patients has been formulated.