The study of anti-inflammatory and reparative activity of Combisept ointment
The article gives information on the results of the study of the pharmacological activity of the combined action ointment on Polyethylene Oxide basis, containing Benzalkonium Chloride, Dexpanthenol and Levomycetine (Chloramphenicol) as active ingredients. Using carrageenan inflammation and thermal burns models it was found that the studied ointment has expressed anti-inflammation activity. On linear incised wound model it was also determined that the ointment has reparative activity. On the basis of the received data it was concluded that performance of further pre-clinical and clinical trials are necessary for registration of COMBISEPT ointment in the Ministry of Health of the Republic of Belarus and its introduction into clinical practice.