The influence of nebivolol and ivabradine on high-resolution electrocardiogram of patients with postinfarction cardiosclerosis and sinus tachycardia
258 patients with Q-myocardial infarction right after discharge from hospital are randomized into three groups. Within six months in the control group consisted of 83 people, patients received the standard therapy (acetylsalicylic acid, nebivolol, perindopril, atorvastatin). Patients of the first studied group (n=87) received ivabradine instead of nebivolol. Patients of the second group (n=88) received nebivolol in combination with ivabradine. high-resolution electrocardiogram (HR ECG) readings and also late ventricular potentials (LVP) were registered at the beginning of the research, in 6 months and in 2 years. Combination of nebivolol and ivabradine in second group appeared to be more effective in reducing frequency heart rate and in improving HR ECG parameters, preventing and eliminating of LVP, than using nebivolol without ivabradine in first group.