EXOCRINE PANCREATIC INSUFFICIENCY IN DIABETES MELLITUS: INCIDENCE, PATHOGENESIS, DIAGNOSIS AND TREATMENT
The article deals with exocrine pancreatic insuf- ficiency (EPI), which is being detected in a significant number (30-50 %) of patients with diabetes mellitus (DM) type I and II and could potentially affect the compensation of DM. Enzyme re- placement therapy should be considered as one of the most promis- ing treatments in patients with DM. This therapy is preferably to be carried out in accordance with clinical guidelines set out in the recent consensuses, however, with higher doses of modern fourth- generation enzyme preparations such as Pangrol® 25000. Addition- al methods of treatment for EPI in patients with DM are correc- tion of nutritional status using appropriate diet, as well as vitamin replacement therapy.