Effects of Long-Term CPAP Therapy on Vascular Stiffness and Endothelial Function in Patients with Obstructive Sleep Apnea and Arterial Hypertension
Obstructive sleep apnea (OSA) is closely connected with arterial hypertension (AH), obesity, impaired carbohydrate metabolism, dyslipidemia, and endothelial dysfunction. The study was aimed to assess long-term effects of CPAP therapy with autoadaptation to inhale and exhale (A-Flex therapy) on endothelial function and metabolic disorders in patients with OSA + AH. Long-term CPAP therapy in A-Flex mode in comorbid patients with moderate and severe OSA and AH has significant effect on restoring lipid profile, vascular stiffness, endothelial function and can reduce the risk of cardiovascular events.