Value of visfatin level determination in sera of rheumatoid arthritis patients
To study visfatin levels in blood of rheumatoid arthritis patients. We study 120 rheumatoid arthritis patients (the average age was 57, 3+1, 6 years) and 50 healthy persons as control group. Visfatin level was determined with ELISA-test (RaiBiotech, cat № EIA-VIS-1). The increased visfatin level was revealed in 46 rheumatoid arthritis patients (38, 3 %). The visfatin level was 6, 27+0, 59 ng/ml in rheumatoid arthritis patients and 2, 30+0, 21 ng/ml — in control group (р <0, 001). Rheumatoid arthritis patients with high visfatin level had higher desease activity index (DAS28 — 2-nd degree), increased level of antibodies to citrullinated vimentin, higher level of C-reactive protein and erythrocyte sedimentation rate.