Evaluation of ointment "Prolidoxyd" When mechanical skin damage in rats
In the model stencilled wounds in rats investigated the effectiveness of a new combined ranozahoyuval- Noah ointment "Prolidoxyd" containing phenolic hydrophobic propolis preparation (FHPP) and li- dokayin. Drug comparison served as healing ointment natural origin "Vun- dehil", which is used in medicine for the topical treatment of wounds. According to the results planimetric indices ointment "Prolidoxyd" contributed to the reduction of terms pro- healing in 4 days compared to the positive control group and 2 days - compared with ointment "Vundehil." According to the dynamics of biochemical and hematological parameters ointment "Prolidoxyd" la vyyavy- clearly wound-healing effect compared to the ointment "Vundehil." More expressive reparative and anti-inflammatory activity investigated ointment sold by the impact of antioxidant polyphenols and membranostabilizuvalnoho FHPP osmotic activity and hydrophilic ointment bases "Prolidoxyd" unlike fat basis hydrophobic drug comparison.