This is a retrospective review of treatment results of 36 patients with ovarian dysgerminoma
very high growth rate and early spread to near lying organs with the possibility of metastasis to regional metastatic lymph nodes and further to visceral organs. The aim of the study was to study the frequency of various clinical and morphological characteristics and to analyze the results of treatment of patients with dysgerminoma. Materials and methods. 36 patients with ovarian dysgerminoma were under observation. The patients’ data of clinicaland laboratory, instrumental studies as well as on the effectiveness of complex treatment were assessed. Results. According to the data of clinical examination, dysgerminoma involved the right ovary in 16 cases, - the left one in 14 cases, and both ovaries n 6 cases. Assessment of the spread of the tumoral process showed that 17 (47.2%) had stage I had, 11 (30.5%) had stage II. Metastatic lesions of the retroperitoneal lymph nodes were detected in 6 (16.7%) patients, and 2 patients had stage IV of the disease. Organ preserving operations were performed in only 16 (45.7%) patients, chemotherapy at the second stage was received by 36 (100%) patients. Overall survival for the entire group of patients with ovarian dysgerminoma was 88.8%. Relapse free survival rate was 72.2%. Conclusions. The results of the study indicate that ovarian dysgerminomas have a relatively favorable clinical course and are highly sensitive to chemotherapy. This allows organ preserving surgery for young patients without using adjuvant chemotherapy.