SYSTEM OF HAEMOSTASIS AND ATHEROSCLEROSIS
Atherosclerosis is the disease characterized by impairment of multiple vessels involving lower limbs vessels. Coagulation factors existing at vessel impairment zone play important role in the development of pathologic process, they and other factors can be activated by erosion of plaques due to their instability, it results in thrombus in situ formation and vessel occlusion with tissue and organs ischemia. Aim of investigation is detection of correlation between high level of laboratory markers and grade of lower limb ischemia of vascular patients. Laboratory markers analysis of 80 patients treated in vascular surgery department from January to December of 2021 was performed. Elevation of such markers as red blood cell cedimentation rate, fibrinogen and glucose in patients with different grade of lower limb ischemia was detected. Further it let us detect the possibilities of using that markers as predictors of atherosclerosis in early stages.