NEUROENDOCRINE CHANGES IN PATIENTS WITH SCLERODERMA-ASSOCIATED FORM TUMOR
Studying of the neuroendocrine status at patients with a sklerodermiya associated with malignant new growths was a research objective. 334 patients with a sklerodermiya are surveyed, 41 from which had oncological pathology (a tumor - the associated form). The control group was made by 40 healthy faces. It is established that at patients with a sklerodermiya associated with malignant new growths of an internal and a vulvarny neoplasia, oppression of function of neuroendocrine system that is expressed by decrease in level of an adrenokortikotropny hormone, a cortisol, and also β- endorphine in blood of patients is observed. Reaction of an organism to a malignant disease at patients with a sklerodermiya, unlike the sklerodermiya which hasn't been associated with tumoral process, is expressed in more considerable oppression of activity hypothalamo- hypophysial adrenal gland a complex and adoptive processes that testifies to reorganization of neuroendocrine system at pathology of connecting fabric, especially in the conditions of a combination to neoplastic process.