SIMULTANEOUS DETECTION OF THIAMPHENICOL, FLORPHENICOL AND CHLORAMPHENICOL RESIDUES IN FOOD PRODUCTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-UV DETECTION
The paper presents a rapid, sensitive, and safe method of simultaneous detection of thiam-, flor- and chloramenicol in food products by highperformance liquid chromatography-UV detection at 228 and 280 nm wavelength using a combination of QuEChERS and dispersive liquidliquid microextraction. Optimal conditions of sample preparation using QuEChERS and dispersive liquid-liquid microextraction methods ensuring sufficient concentration and additional purification of the extract were selected. The extraction level is 64-87% depending on the matrix. Under selected conditions detected content range was 0,01-5,00 μg/g taking into account that concentration rate was 10. Relative standard deviation of the test results did not exceed 0,09. The test duration is 1,0-1,5 h.