Isolated pulmonary metastases: evolution of the treatment technologies
The lung is the most commonly attacked organ in metastatic disease. In many patients who were successfully cured of primary cancer, pulmonary metastases for a long time may be the only, and sometimes the final manifestation of the disease. This kind of dissemination is known as isolated lung metastases. The prognosis for untreated patients with pulmonary metastases is unfavorable: 5-year survival does not exceed 5%. This survey considers the evolution of technologies for the treatment of isolated metastatic lung lesions from surgical metastasectomy to combined methods of high-dose regional chemotherapy.