Pathogenetic features of diseases of the digestive system on the background of the food allergy in children with impaired posture
Aim of the study: determination of the features of clinical and metabolic changes, as well as the relationship of indicators of systemic immunity and dyslipidemia in preschool children with impaired posture and digestive diseases on the background of food allergies. Material and methods. We examined 157 children with impaired posture Lugansk center for social rehabilitation of disabled children "Revival", suffering from food allergies, of which 78 children with gastrointestinal form and 79 people with skin. Digestive tract lesions were classified as: chronic gastroduodenitis, chronic enteritis, dysfunctional disorders of the biliary tract and colon dyskinesia. Clinical, biochemical, allergological and immunological studies were carried out. Results. It was found that in children with chronic digestive tract pathology against a background of food allergy, an atherogenic shift in the spectrum of lipoproteins was detected. Hypercholesterolemia, dysammaglobulinemia, ketosis and an increase in alkaline phosphatase activity are characteristic. Conclusion. Dyslipidemia is accompanied by changes in systemic immunity, depending on the atherogenic orientation.