New Aspects of the Pathogenesis of Obstetrical and Perinatal Complications in Women with Alimentary Constitutive Obesity
Pregnancy in women with alimentary constitutive obesity occurs on a background of chronic stress and proceed with increased activity of the sympathetic nervous system, which leads to insulin resistance and hyperinsulinemia, which triggers in the body a number of pathological processes: tension of sympathoadrenal and pituitary-thyroid system, disorders in lipid and protein metabolism, hormonal changes, increase of cortisol, leptin levels in the blood. Along with that psycho-vegetative disorders, that are closely associated with improper feeding, are observed. This leads to abnormal weight gain, which results in obstetrical and perinatal complications.