THE CONTENT OF METABOLITES OF NITRIC OXIDE AND SOME INDICATORS OF BLOOD COAGULATION IN PATIENTS WITH PSORIASIS
The assessment of the content of levels of nitrite (NO2), prothrombin index (PTI), fibrinogen, SFMC (soluble fibrin-monomer complexes), APTT serum and platelet count in patients with psoriasis, depending from the clinical form, severity and activity disease is presented in the article. We observed 152 patients with psoriasis in age from 18 to 67 years. The 20 healthy volunteers who were representative by gender and age constituted of control group. The increase of the content of NO2 in the serum of patients with increasing the severity and activity of disease were established. Violations of the blood coagulation system in psoriasis are show by increased activity of coagulation link, intensification continuous intravascular coagulation, which depend from the level of severity and activity of disease.