ISOLIMONIC AND ALPHA-KETOGLUTARIC ACID TREATMENT RESULTS IN COMPLEX THERAPY OF ARTERIAL HYPERTENSION
The goal of the research is to estimate the clinical efficiency of isolimonic and alpha-ketoglutaric acid medication used with the basic therapy for arterial hypertension treatment. The research includes 65 patients. Basic antihypertensive therapy was carried out under the standard scheme of arterial hypertension treatment. All patients was devided into 2 main groups (M, n=19 and n=17) and control one (C, n=29). Alpha-ketoglutaric and isolimonic acid were added to the basic therapy of the main group patients, for the control group patients placebo were added. Test duration was 10 days. The results of the research showed, that ten-day treatment with the energy metabolism substrates of these patients leads to decrease of daily DAP, due to decrease of night component, to increase of SAP tolerance to physical activity and to decrease of high level of personal anxiety.