Dialectics of Oral Hypoglycemic Agents Use in Patients with Diabetes Mellitus Type 2: Hypoglycemic Activity and Cardiac Safety
The article presents a review of the major studies of the effectiveness of combination therapy with glimepiride and metformin in patients with diabetes mellitus type 2. This therapeutic approach can simultaneously affect the main pathogenesis links. Proven efficacy and safety of the combination of glimepiride and metformin (Duglimax) can be recommended for the treatment of patients with diabetes mellitus type 2 due to minimal risk of hypoglycaemia, lack of weight gain, positive effects on the cardiovascular system and the progression of atherosclerosis.