Clinical and morphological characteristics and microbiological analyzes of the hip joint tissues in patients with avascular necrosis of the femoral head
The pathomorphological and microbiological analysis of the hip joint tissues of 26 patients with avascular necrosis of the femoral head was performed. Materials for the study were the femoral heads, synovial membranes, removed during hip replacement surgery, the synovial fluid, serum of patients. The degenerative and destructive processes in the cartilage, necrotic cancellous bone of the femoral head, which corresponded to III-IV stage of disease were described. The characteristic of dystrophic and inflammatory processes in synovial membranes was given. Screening search was revealed C. Trachomatis, Herpesviridae, Mycoplasma and antibody specific to it in a number of samples. Based on the ultrastructural research the changes in synoviocytes (A- and B-cells), chondrocytes in femoral head necrosis were described.