EFFECTS ON THE PROPERTIES OF POLYMERS STR. EQUI SUBSP. ZOOEPIDEMICUS, ISOLATED FROM HORSES
A streptococci isolated from horses lost their ability to grow on nutrient media, in connection with the violation of the integrity of the cell wall after contact with the copolymer dialildimetilammonychloride with dialilguanidinatsetatom, and in the case of dialilguanidinatsetatom retained the ability to grow, but changed some of the properties. The data obtained suggest that the copolymer with dialilguanidinatsetatom with biocidal for Str. equi subsp. zooepidemicus. Clearly shows loss of integrity of the cell wall due to chemical interaction with components of the cell wall, resulting in increased porosity and rupture. Earlier studies on the interaction of the polymers with erythrocytes and bacterial cells, have shown that some polymers rapidly bound to the cell wall and cytoplasmatic membrane, and then penetrate into the cytoplasm of cells and nuclear matter. Increases cell membrane permeability for low-molecular and high-molecular substances. The cationic polyelectrolyte dialilguaninatsetat also has an impact on culture, biochemical and pathogenic virulence Str. equi subsp. zooepidemicus, isolated from horses, breaking its enzyme system and the structure of the cell wall. However, it leads to loss of streptococcal cells as in the case of a copolymer dialilguanidinatsetatom. Str. equi subsp. zooepidemicus often isolated from horses with signs of respiratory infections. Copolymer dialilguanidinatsetatom has a bactericidal action associated to the violation of the integrity of the cell wall Str. equi subsp. zooepidemicus, which leads to a change in its form, as well as violation of the permeability and tear. Dialilguaninatsetat impact on culture, biochemical and pathogenic virulence Str. equi subsp. zooepidemicus, but it does not cause their death.