FOOD ANAPHYLAXIS IN CHILDREN: RETROSPECTIVE ANALYSIS OF 53 CASES
Introduction. There are no studies on anaphylaxis in children in Russian Federation therefore this problem is a topical issue. Background. To determine the etiology, natural course of food anaphylaxis in Russian Federation children, to analyse the therapeutic care of anaphylaxis. Methods. 53 patients with food anaphylaxis were included in the study. All patients completed a questionnaire included questions about the triggers, clinical manifestations and treatment of anaphylaxis. Results. In 94% episodes of anaphylactic reactions occurred at home, 2/3 (66%) of patients had two or more episodes of food anaphylaxis before, 5 (8%) infants didn’t have allergic diseases, 23 patients (43%) had anaphylactic reactions to more than one product. Cow’s milk (43%) was the most common cause of anaphylaxis. Cow’s milk caused anaphylaxis in 67% of children under 2 years (p<0,0001). In 98% of patients target organs of anaphylactic reacnions were skin / mucous and in 87% — respiratory system. In the group of children over 2 years old cardiovascular symptoms were more often (p<0,00l5). In the majority of patients delayed diagnosis of anaphylaxis more than 4 years was estimaited. Only 7% of children had the injection of adrenaline during anaphylactic reactions. Conclusion. The results of the study showed the lack of experience in investigation of anaphylaxis in the Russian Federation, which consequently leads to incorrect diagnosis and not effective treatment.