STUDY OF LOCAL IMMUNITY OF THE ORAL CAVITY OF PATIENTS WITH FIXED PROSTHETIC AESTHETIC DESIGNS AND INFLAMMATORY PERIODONTAL DISEASES
The work studied the local immunity of the oral cavity of patients with fixed prosthetic aesthetic designs and inflammatory periodontal diseases. The study included 90 patients with fixed prosthetic aesthetic designs and inflammatory periodontal diseases and 21 people (control group) with no orthopedic constructions and periodontal diseases. Oral immunoglobulins IgA, sIgA, IgG, IgM, IgE, interleukins IL-4, IL-6, IL-1β, IF-α levels were identified by the method of enzyme immunoassay analysis. As a result of ourstudies we revealed increased IgA concentration and tendency to sIgA increase in oral liquid of both studied groups. We determined the increase of IgE, an allergization marker, in patients of the main group. In the study of interleukin of the oral liquid in patients of the control group we determined statistically significant decrease in the concentration of IL-4 patients of the main group; there was an increase in IL-6 and IL-1β in patients of the main group. In patients with fixed prosthetic aesthetic designs and inflammatory periodontal diseases there is an imbalance of humoral immunity in the oral cavity.