EXPERT EVALUATION OF DRUGS USED FOR DETOXIFICATION THERAPY AT REHABILITATION DEPARTMENT AT ADDICTION CLINIC
Aim. Evaluation of consumer properties of the drugs used in detoxiﬁcation therapy in psychoactive substance poisoning at the intensive care unit at addiction clinic was the aim of the study. Material and methods. Expert evaluation of the range of drugs used for detoxiﬁcation therapy, registered in the State Registry of Medicinal Products of Russia, present on the regional pharmaceutical market and in addiction clinics of the Republic of Tatarstan, was conducted in the course of the study. Results and discussion. Comprehensive assessment of consumer properties of detoxiﬁcation treatment drugs was carried out by expert doctors working in addiction clinics of the Republic of Tatarstan. 33 expert doctors were surveyed (total population was 36), which ensures the representativeness of the sample with 95% accuracy. As a result of the analysis of data on competence assessment in narcologists who participated in the expert assessment of consumer properties of the drugs for detoxiﬁcation therapy, it was found that 52% of the experts had an average level of competence and 48% had a high level. Factors that inﬂuenced the choice of drugs were therapeutic efﬁcacy (43,2%), safety (22,1%), contraindications (8,3%), rationality of the dosage form and the dosage itself (21,1%), and price availability (5,3%). Using an average weighted score the drugs tested were ranked for all of the analyzed parameters (top 10). The coefﬁcient of concordance of expert opinions during the ranking of the drugs was in the range of 0,72-0,88, which suggests that the experts slightly differ in their opinions regarding the consumer properties of the studied drugs. The coefﬁcients of variation of expert opinions during the ranking of the drugs ranged from 10 to 20%,i.e. the total data presented is homogeneous. The results of the evaluation of consumer properties of the drugs for detoxiﬁcation therapy were systematized by pharmacotherapeutic groups. The study allowed identifying the leaders of medical preferences in each group. Conclusion. The medical preferences of drugs for detoxiﬁcation therapy at the intensive care unit of the addiction clinic were revealed.