PREDICTION OF RISK FOR PANIC DISORDER FORMATION
Psychological, immunological and hormonal examination of 90 persons (mean age 42.16±9.25 years) under inpatient treatment at the first clinical psychiatric ward of the clinics of Mental Health Research Institute of Tomsk NRMC was carried out. According to criteria of ICD-10, all patients were divided into two clinical groups: 50 patients (group 1) were diagnosed with adjustment disorder (F 43.2), 40 patients (group 2) were diagnosed with panic disorder (F 41.0). Based on data of complex examination a method of prediction of risk for panic disorder formation at an early stage of the disease was proposed – at the stage of adjustment disorder by the way of evaluation of the level of state and trait anxiety, identification of concentration of cortisol and immunological parameters in blood, and during heightening of the level of state anxiety above 57 points, concentration of cortisol in serum of blood above 661 nmol/l and lowering of the number of natural cells-killers (NK-cells) below 10 % it is possible to predict risk for formation of panic disorder in patients. Method can be broadly used in medicine in healthcare for prediction of risk for panic disorder formation at the early stage of the disease and targeted carrying-out of the complex therapy.