Nutritional approach to prevention of overweight in the neonate
A systematic analysis of clinical, biochemical and experimental data on the etiology of macrosomia is presented. An apparent significance of metabolic disorders (gestational diabetes, obesity) and iatrogenic factors (adrenomimetics, corticosteroids) as risk factors for macrosomia permits to hypothesize that preventive measures should be realized well in advance of the onset of pregnancy, including personalized pharmacotherapy, recommendations on nutrition, physical activities and other lifestyle aspects aimed, in particular, at decreasing overweight. Special attention in preventing macrosomia is paid to nutritional perspective - using physiological doses of certain vitamins and trace elements.