Posterior Reversible Leukoencephalopathy Syndrome: Clinical Case and Literature Overview
Objective of the Paper: To discuss the complexities in diagnostics of posterior reversible leukoencephalopathy. Key Points: The article discusses a case history of severe posterior reversible leukoencephalopathy syndrome (PRLS) associated with uncontrolled arterial hypertension and rheumatoid arthritis. The patient had headaches, reversible loss of vision, visual hallucinations. Clinical symptoms were evolving gradually for a month and then confused consciousness appeared which was associated with raised blood pressure. MRI results showed an extensive vasogenic oedema with small areas of limited diffusion. A literature review was also carried out to illustrate the clinical neuroimaging manifestations of this disorder. Conclusion: This case illustrates the versatile clinical neuroimaging manifestations of PRLS and its severity with a number of contributory causes present.