CHOISING OF HIPNOTIC AGENT FOR MAINTANENCE OF ANAESTHESIA DURING CARDIOPULMONARY BYPASS
Enhanced Recovery After Surgical Intervention (ERAS) is a multimodal, multi-disciplinary treatment optimization program that accelerates the recovery of patients undergoing surgical (including cardiac surgery) interventions throughout their perioperative period. One of the important components of this strategy is early extubation (within 6 hours after the end of the surgery). Early extubation can reduce the risk of ventilator-associated pneumonia, hospital leigh of stay and cost of treatment. Traditionally, in our clinic, we used total intravenous anesthesia during CPB, and prior to the use of the ERAS protocol, thiopenal was the standard for maintaining anesthesia during cardiopulmonary bypass, as a drug that protects the brain. Given the presence of a cumulative effect that lengthens the patient's awakening time, there is a need to choose a hypnotic alternative to thiopental that does not have this effect. In this regard, we conducted a pilot prospective randomized study to compare the effect of drugs for maintaining anesthesia (sodium thiopental - group 1; propofol - group 2) during perfusion (cardiopulmonary bypass) on the total duration of stay of patients on mechanical ventilation with an uncomplicated course of surgery. A statistically significant decrease in the time of perioperative mechanical ventilation was shown in patients receiving propofol.