DYNAMICS OF FOLLICULOGENESIS OF SEXUALLY MATURE AND NEONATAL OVARIAN TISSUE UNDER CONDITIONS OF LONG-TERM HETEROTOPICAL TRANSPLANTATION
In this work, a comparative analysis of dynamics of morphological development and endocrine function of transplants of sexually mature and neonatal ovarian tissue was performed under conditions of bilateral ovariectomy of animals-recipients. It has been established that at transplantation of the sexually mature ovarian tissue there were observed all stages of folliculogenesis and preservation of endocrine function at long-term observation (up to 100 days). At transplantation of neonatal ovarian tissue there was revealed a pathological picture of its development: hyperplasia of stromal structure and formation of cysts and cystomae. Follicles of different degree of maturity were revealed in 30 % of animals at the 30th day of observation. A significant increase of concentration of sex hormones as compared with ovariectomied animals has been shown only at early stages after implantation (30 days).