Erythrocyte metabolism and hemo dilution in patients with generalized forms of meningococcal infection and purulent meningitis
Impairment of reological properties of blood play an important role in combined pathologies and urgent conditions development especially in severe forms of generalized meningococcal infection and purulent meningitis. Such impairments are indicators for infusion hemodilution therapy. We have determined simultaneously hematocrit and indexes of energetic metabolism of erythrocytes detecting in them ATF, ADF, AMF, 2,3DFG energetic charge. Patients were prescribed infusion therapy. There is reliable correlation of non-linear character between the studied parameters and hematocrit demonstrating increase of metabolic activity of erythrocytes with simultaneous diminishing of hematocrit level.