Pulmonary Arterial Hypertension Associated with Anorexigenic Drugs
The use of certain drugs and anorexigenic drugs (amphetamine, aminorex, fenfluramine, dexfenfluramine, benfluorex, methamphetamine and phenylpropanolamine) contributes to the formation of pulmonary hypertension, which causes premature death. With long-term observation, it was noted that suppressing appetite when taking them is accompanied by an increase in pressure in the pulmonary artery and pulmonary vascular resistance. Many of the anorexigenic drugs are withdrawn from the market and their sales are discontinued in Europe. Uncontrolled use of drugs whose action is aimed at reducing appetiteincreases the risk of developing pulmonary arterial hypertension and does not have a positive effect.