Effect of multicomponent platelet and plasma apheresis on hemostasis in donors
The evaluation of the donor hemostasis system during simultaneous platelet and plasma exfusion by apheresis was carried out. It was found that the combined collection of a therapeutic dose of platelet concentrate (more than 300 x 10<sup>9</sup> cells) and plasma (up to 600 ml) in donors did not have a negative impact on the status of the plasma hemostasis of donors. Changes with hypocoagulation orientation immediately after donation were temporary and did not go beyond the values taken for the physiological norm.