Efficacy of rupatadine in skin allergies
The article addresses the management of acute and chronic urticaria. Standard or high doses of non-sedating second-generation antihistamines are regarded as first-choice therapy for urticaria. Rupatadine is an antihistaminic agent exerting additional antagonistic effects on some other allergic mediators involved in urticaria formation. Clinical studies have demonstrated efficacy and safety of rupatadine in acute, chronic and acquired cold urticaria.