APPLICATION OF VITAMIN D DERIVATIVES TO PSORIASIS THERAPY
The clinical efficiency of synthetic vitamin D substitute and its effects on blood calcium level as applied to the therapy of long-lasting, extensive, toprid psoriasis resistant to previous therapy has been studied. 18 psoriasis patients have been monitored. They have extensive psoriasis affecting over 50 % of the skin. The clinical effect was achieved after 7 days of the medication therapy: the papulas and spots became flat and discolored with no skin flaking; after 3 weeks the eruptions significantly reduced. Total blood calcium during and after the therapy was maintained at 1.6 mmol/l.