Effect of dalargin on pancreatic enzymes activity in blood of rats with L-arginine-induced acute experimental pancreatitis. Work is dedicated to the acute experimental pancreatitis and prophylactic efficacy increasing through the dalargin using
The obtained data indicate that both forms of dalargin using with prophylactic aim was effective in all the tests that were performed which is also the experimental background of dalargin use for prophylaxis of acute pancreatitis. It was shown that dalargin prophylactic effects continued for 30 min after its injection while its liposomal form - 72 hrs before development of L-arginine-induced acute experimental pancreatitis. This is in favour of prevalence of prophylactic ac- tion of liposomal dalargin. The conclusion was made that expressed the prophylactic activity of liposomal dalargin, that exceeded the activity of free dalargin is the experimental background of the compound use in the prophylactic and cur- ing schemes for patients with acute pancreatitis.