CHOLESTASIS IN PREGNANT WOMEN
The aim of this research is to study the peculiarities of the course of pregnancy, childbirth, postpartum period and newborn status in intrahepatic cholestasis of pregnant women. Intrahepatic cholestasis of pregnanсу women is a severe, cholestatic liver disease that not only affects the quality of life of pregnant women, but also negatively affects the condition of the fetus during pregnancy. If during the first pregnancy a woman ill with intrahepatic cholestasis, the probability of its recurrence in future pregnancies is 45-70 %, at the same time, it can develop after several pregnancies with normal flow. Intrahepatic cholestasis of pregnant inherited in an autosomal dominant type is more common among women, mothers or sisters who have suffered this disease. On the basis of the contradiction are presented the available data, it should be recognized that to date, the etiology and pathogenesis of intrahepatic cholestasis has not been studied. The most common hormonal and genetic theories of the development of intrahepatic cholestasis.