Possibilities of Pharmacological Correction of Thrombocyte Dysfunction of Newborn Calves with Dyspepsia
Increase of aggregative function of thrombocytes in vitro and in vivo is revealed at newborn calves with dyspepsia. In the base of these abnormalities, abnormalities of cholesterol and phospholipids correlation in thrombocyte membranes, increase of middle molecules level content in plasma and blood platelets, activation of lipids peroxidation in them, synthesis strengthening in vascular wall of Villebrand factor and increase of thromboxaneformations level in blood platelets are laid. Thrombocytes activation is a leading reason of blood coagulation increase of newborn calves with dyspepsia. Correction of abnormalities of thrombocyte link of hemostasis is possible with help of pathogeneticly substantiated complex from phosphopag, ecos and calcium gluconate, able to decrease middle molecules level in an organism and to correct lipids peroxidation.