CHANGING OF THE PHYSIOLOGICAL AND IMMUNOLOGICAL INDICES OF SILURUS GLANIS AT DEFEAT BY ICHTHYOPHTHIROSIS
We studied the physiological changes of Silurus glanis, cultivated in ponds of second aquaculture zones at ichthyophthirosis. The diagnosis was made by the presence of multiple tubercles on the body of the fish and the detection of the ichthyophthirosis pathogen. Infestation intensity was 1.5-2.5 units/g of body weight of fish. We determined the hematologic, cytochemical and biochemical parameters. It was revealed that in the blood of affected fish at the age of 1 year, a large proportion of eosinophils and a smaller proportion of lymphocytes compared to healthy fish. This is indicative of immune activation in the disease. Affected fish were divided into two groups of 100 fish in each. One group was kept in the bath with solution for one hour. Composition of the solution: 20 liters of water, 2 big spoons NaCl, 60 mg furazolidone, 100 mg / l methylene blue. Another group was not treated. Then we put the fish in different ponds for growing. In autumn during the catching the fish of the first group has no the clinical signs of disease. But the fish this group had increased the percentage of blast forms of white blood cells by reducing lymphocyte; Activity transaminases, LDH, glucose and increased total protein increased in comparison to healthy fishes.