The use of supplementary food products in infants with compromised allergic family history
Due to the growing spread of allergic diseases among the population of the Russian Federation an important role in modern nutrition science belongs to composition of a nutritional ration for children with this pathology, including development and selection of hypoallergenic food products. In order to assess the sensitizing potential of the supplementary foods Agusha® «First spoon» (JSC «Wimm-Bill'-Dann», Russia) an open prospective controlled clinical study was performed. The cohort of study comprised infants aged 6-12 months with compromised allergic family history, who were breastfed, or formula-fed, or received mixed feeding. The sample consisted of 612 participants including the control group (n = 180). The main safety endpoints were the percentage of patients with the clinical signs of allergic reaction associated with the intake of the studied supplementary food in the experimental groups; the frequency of development of undesirable and serious undesirable events associated with the intake of the studied supplementary food in the experimental groups, and also percentages of patients with the clinical signs of allergy in the basic and control groups. The results of the study of the supplementary food products Agusha® «First spoon» have shown that these products are characterised by a good safety and tolerance profile and might be recommended as supplementary food for infants, including those with compromised allergic family history.