REGULATION OF RIBOSOMAL PROTEINS SYNTHESIS IN PROKARYOTES
Protein biosynthesis is the primary activity of a living cell. Ribosome biogenesis requires proper regulation of ribosomal proteins genes expression, which is essential for the balanced synthesis of proteins and RNA. In this review, we discuss some features of the ribosomal protein synthesis autoregulation in prokaryotes. We discuss the mechanisms of inhibiting the synthesis of ribosomal proteins, namely, the competitive inhibition, the “trap” mechanism, and the retroregulation. The review describes examples of the regulation of protein synthesis by individual ribosomal proteins and their complexes.