DNA BIOBANK ORGANIZATION, ITS ROLE IN SCIENTIFIC RESEARCH
Introduction. Modern molecular genetic studies of gene polymorphisms' for susceptibility to various multifactorial diseases require a large array of analysis for clinical information and genetic data that characterize the individual of each person. For this purpose, biological materials information databases are being created, which play a central role in combining a large volume of biological samples and information about them. Objective: Show the significance of the DNA biobank organization and its role in scientific research Results: The DNA biobank was organized within the InterPregGen 7 European Commission's Framework Program "Genetic Research of Preeclampsia in Populations of Central Asia and Europe" under Grant Agreement No. 282540 at the "Scientific Center for Obstetrics, Gynecology, and Perinatology" Ministry of Health of the Republic of Kazakhstan (SCOGP). DNA isolated by the saline method from the recruits peripheral blood according to the studied diseases. Molecular genetic studies were carried out by TaqMan method of unified specific amplification and real-time genotyping (PCR real-time) using test systems ("TestGene" Russia) for molecular genetic studies. Molecular genetic studies made out by TaqMan method of unified specific amplification and real-time genotyping (PCR real-time) using test systems ("TestGene" Russia) for molecular genetic studies. Conclusions: The biobank DNA collection is used to conduct scientific research of multifactorial diseases with unexplained pathogenesis, to identify biomarkers, create diagnostic tests for scientific and technical programs.