Infrared Fourier spectroscopy in new technologies of oncological diseases diagnostics
With the use of the developed technologies of IR Fourier spectroscopy, the research results of healthy and ill animal’s tissues are presented. Lung tissues of healthy mice after draft of melanoma В-16 and lung tissues in the course of chemotherapy are studied. Mammary gland tissues of mice with sarcoma, the 180 strain, and tissues after being treated with the new medical products are studied. As the new preparations coordination compounds synthesized by the authors on the basis of complexes of palladium and phosphoric acid derivatives are used. The presence of concrete spectral signs in tissues of malignant new growths is identified. The changes in IR spectrum when treating the damaged tissues in the range of 1700-1600 sm-1 for valence vibrations of С=О groups are observed. After treatment the IR spectrum of tissues corresponds their signs of the IR spectrum of healthy tissues. The main result of the work is the substantiation of the possibility to solve consistently with the application of IR Fourier spectroscopic technologies two concrete biomedical problems: to carry out early diagnostics of tissues in damaged on the molecular level and to make the real control over the realization of the chemotherapy process of tumors.