PELVIC INJURY PATHOGENESIS HEMATOLOGICAL AND BIOCHEMICAL PECULIARITIES IN SUFFICIENTS WITH SIGNS OF CONNECTIVE TISSUE DYSPLASIA
Purpose: to reveal the pelvic trauma pathogenesis hematological and biochemical features in patients with connective tissue dysplasia. Material, methods and design. We analyzed the case histories of 211 patients with injuries of the pelvic bones who were treated in the trauma departments of the RTC and the Hospital 17 in Donetsk from 2016 to 2021 and 40 patients in the control and comparison groups. Results and conclusions. 50 different general clinical and instrumental indicators were analyzed. There were 29 of them - correlations of various strengths and directions were traced (from very weak r = 0.222 to high r = 0.767). The presence of fragments and their displacement was not directly proportional (r = 0.778; p <0.05) correlated with the data of instrumental research methods (X-ray, SCT), which can be regarded as a problem (error) in diagnosis. Of the 29 indicators, we were most interested in the clinical significance of the number of bed-days spent in the hospital and the presence of complications. We found it interesting to find out and pathogenetically substantiate the factors and relationships that affect these indicators, important for the patient. This article presents an analysis of 15 hematological and biochemical parameters (RBC, ESR, protein, bilirubin, transaminases, urea, creatinine) that have shown interrelationships in the pathogenesis of pelvic injury in individuals with signs of CTD. The obtained correlations will subsequently form the basis for the development of a pathogenetic mathematical model for predicting complications and unfavorable outcomes of pelvic trauma in persons with signs of CTD.