LATENT FACTORS OF QUALITY OF LIFE IN MULTIPLE SCLEROSIS PATIENTS WITH COGNITIVE PECULIARITIES AND COMORBID DEPRESSION
We studied the quality of life of 96 patients with multiple sclerosis (MS) depending on the availability of cognitive and depressive disorders identified latent factors determining and limiting the quality of life in MS patients. To determine the quality of life was used questionnaire SF-36. 53 the patient to identify depressive disorders tested using the depression scale Beck. In 43 patients for the detection of cognitive impairment was used the MMSE scale. Cognitive impairment identified in 23 patients (53.5 per cent). A reliably lower the quality of life in patients with cognitive deficit scales: PF, RP, VT, and BP. Comorbid depression identified in 33 patients (62.3 percent). In patients with MS without comorbid depression magnitude scales characterizing physical (PF, RP, GH) and psychological (VT, MH) components of health significantly higher than in patients with depression. From the factor loadings MS patients with cognitive and depressive symptoms in the first place come the psychological components of quality of life. In patients without cognitive and depressive disorders is a combination of factor loadings physical and psychological component of quality of life.