Influence of coffee on mucuciliary clearance in bronchopneumonia in calves
Studies have been carried out to study the effect of caffeine on mucociliary clearance in calves of patients with bronchopneumonia. It was found that caffeine (1,3,7-trimethyl-xanthine), in addition to the known effect on the respiratory center, activates the drainage function of the bronchi. The pharmacological effect depends on the dose of the drug and the clinical state of the animal. The most complete combination of analeptic and expectorant action was observed when caffeine was administered at a dose of 1.5 mg / kg to calves with respiratory diseases of mild or moderate severity. Increasing the dose of the drug or prescribing it to patients in severe condition can cause complications in the form of the syndrome of "swamping" of the lungs and increasing the severity of respiratory failure.