Predictors of persistant post-operation cognitive dysfunction in 2 type diabetes patients after coronary bypass grafting
Aim. To study predictors of long-term post-operation cognitive dysfunction (POCD) in patients with diabetes mellitus 2 type (Dm), underwent coronary bypass grafting (CBG) under on-pump conditions. Material and methods. Totally, 54 men included, with DM 2 type, underwent scheduled on-pump CBG, at the age 45-69 y.o. All patients, together with standard clinical assessment, were neurophysiologically tested on the 3-5th day after operation, on 7-14th day and in 1 year after CBG. As factors, suggestively significant for persistent POCD development, were selected: integral parameter of patents adherence to treatment, moderate cognition disorders (MCD) before operation, anxiety level (AL) and progression of carotid arteries (CA) stenoses, measured in 1 year before the operation. Results. In DM2 patients after on-pump CBG, the following most significant factors were identified as predictors for POCD: CA stenoses progression, high AL, low integral parameter of adherence; this allows for high probability level of prediction of POCD in 1 year after CBG. Conclusion. The obtained data demonstrated significance of the factors as CA stenoses progression, high LA and low adherence to treatment for development of persistent POCD in DM2 patients after on-pump CBG.