COMPARATIVE STUDY OF HAEMOSTASIS, FIBRINOLYSIS AND LIPID SPECTRUM IN PATIENTS WITH ACUTE STROKE AND DISCIRCULATORY ENCEPHALOPATHY
We found dysfunction of fi brinolysis, haemostasis and lipid spectrum in patients with acute stroke and discirculatory encephalopathy (DE): high level of triglycerides and lowered HDL-cholesterol in both groups (particularly in patients with acute stroke). Fibrinogen concentration, D-dimmer level and fi brin clot density were much higher in comparison with controls that testifi ed to haemostasis activation. At the same time increasing of AT-III activity (especially in patients with DE), elongation of clotting time and fi brin fi bers formation time were associated with protective reaction as answer on thrombosis danger. It is possible that fi brinolysis inhibition with normal t-PA activity was excited by fi brin resistance to own fi brinolytic system. Improving of some parameters was detected after «cuff - test» in control group.