Hemostatic features and arteriolar blood flow in women with type 2 diabetes
We examined 65 women with type 2 diabetes and 28 healthy women (volunteers). Hemostatic system was evaluated by the aggregation of platelets and some coagulation parameters. Functional microcirculation was studied using Doppler ultrasound. The study found that in patients with type 2 diabetes the violation of hemostasis was to the side of hypoaggregation (65%) and hyperaggregation (35%). In the coagulation unit also there are indices showing anticoagulation and hypercoagulable. The most pronounced changes in the vascular-platelet unit of hemostasis (hypoaggregation) and plasma coagulation (hypocoagulyation) were observed in severe decompensation and hypertriglyceridemia in patients with type 2 diabetes. In the patients with type 2 diabetes, especially with hypoaggregation, decreased values of speed blood flow, as well as lower resistance of the skin vessels and worse ability to dilatation in the test with ischemia were noted.