The features of the course of tuberculosis of central nervous system in hiv-positive patients
Th ere was performed the analysis of anamnestic, X-ray and laboratory data, received from 192 HIV-infected patients with TB of central nervous system. Th ere were revealed such atypical disease manifestations as shortening or prolongation of prodromal stage, absence of brain tunic irritation (in 15.9% of cases) and cranial nerve lesion (in 1/3 of patients) symptoms and also a non-characteristic spinal fl uid composition for TB meningitis (high neutrophilous pleocytosis, absence of fi brin prolapse, extremely rare detection of MTB). Th e detected clinical and laboratory features contribute to the late detection and as a result to high death rate of patients in this group, indicating the necessity to fi nd the new approaches to the diagnostics of TB of central nervous system.