Clinical and instrumental correlations in young patients with migraine
The article presents the analysis of the published data and the results of our own clinical and Doppler examination of 116 young patients with migraines (aged 18-45). We have carried out clinical and neurological examinations, assessed the intensity of the degree of reduction of the functional activity of the patients, studied the state of the main arteries of the head, cerebral arteries, as well as cerebrovascular reactivity using Doppler sonography. Cerebral hemodynamics in migraine attacks is characterized by a vasospasm pattern in migraines without aura and a pattern of obstructed perfusion in migraines with aura in the middle cerebral arteries, as well as increased perfusion in the cerebral arteries. For patients with migraine without aura, the characteristic Doppler pattern is hyper-responsiveness to hypercapnic stress, for patients with migraine with aura - hyper-reactivity to hyperventilation load, reflecting hyperconstrictor vascular response. The presence of extravasalvertebral arteries compression in patients with migraine without aura and with aura, as well as hypoplasia of the vertebral artery in the group of patients with migraine with aura was shown.