EVALUATION OF CLINICAL EFFECTIVENESS OF INTRADERMAL AUTOSERUM THERAPY IN CHILDREN WITH ATOPIC BRONCHIAL ASTHMA
Objective of the study. Evaluation of clinical effectiveness of intradermal autoserum therapy in the treatment of children with atopic bronchial asthma (BA). Materials and Methods. We examined 3 groups of children with BA, the treatment included: intradermal autoserum therapy (AS) (n=44), intradermal autoserum therapy in combination with basic treatment (AS + BMT) (n=51), only basic treatment (BMT) (n=15). The assessment of asthma control in children with usage of AC-test before treatment, 3 and 6 months after the treatment, was carried out during the study. Quality of life in children was assessed using a Ped sQL™ 4.0 questionnaire, before treatment and after 1 year after it. Results. In the groups of children, who received only AS (p<0,01) and AS + BMT (p<0,001) 6 months after the treatment, there were signs of improvement in asthma control in all age groups. We also registered improvement of quality of life, in children of those groups 1 year after the treatment (group AS: p<0,05, p<0,001, p<0,01; AS + BMT: p<0,01, p<0,001). Conclusion. Autoserum therapy with basic medical treatment can lead to both better control and improvement of children's quality of life if compared with the group of children without autoserum. Thus, intradermal autoserum therapy enhances the effectiveness of immunorehabilitation in children with asthma by way of improved asthma control.