PROSPECTS FOR THE USE OF TURMERIC IN DENTISTRY
Turmeric is a well-known medicine of ancient medicine. Turmeric grows in tropical countries - in India, Iran, Indonesia, China, Vietnam. Due to its rich chemical composition, mainly turmeric curcumin has an antibacterial, anti-inflammatory, antioxidant, antitumor, wound healing, hemostatic effect. Turmeric is promising for the synthesis of new drugs for the treatment of mucositis. Turmeric powder with glycerin can serve as an excellent symptomatic agent in the treatment of burning sensation in submucous fibrosis of the oral mucosa. Turmeric can be confidently recommended as a natural antibiotic film and antioxidant against bacteria isolated from dental plaques and dental installation water lines. Extracts of Curcuma longa have antimicrobial efficacy against common periodontopathic bacteria. Current evidence suggests that topical application of turmeric or curcumin (as a gel or rinse solution) is effective in controlling signs and symptoms of oral mucosa in patients with mucositis of various etiologies. Randomized clinical trials have shown that black pepper turmeric and nigella sativa improve mouth opening, burning sensation, and serum superoxide dismutase levels in patients with oral submucosal fibrosis. The study showed that curcumin in combination with piperin inhibits osteoclastogenesis in vitro without causing cytotoxic effects in periodontal ligament cells, and this combination is promising for the prevention and treatment of replacement resorption in transplanted remote teeth.