Organic nitrates in ischemic heart disease
Organic nitrates as antianginal drugs are necessary in the treatment of patients with coronary heart disease. Addition of ideas about the mechanisms of action of nitrates: the effect on vasodilation, platelet function, determining hemodynamic effects, justifies their differentiated use in various functional classes of angina pectoris, determination of the location of short and long acting nitrates with the release of the nitratefree period makes it possible to avoid drug tolerance.