Clinicepidemiological characteristics of influenza А (H1N1) pdm09 during 2012-2013 epidemiological season in Moscow
Results of clinic-epidemiological monitoring of influenza conducting in Moscow inflectional clinical hospital N 1 during 2012-2013 are presented. Influenza A (H1N1) pdm09 dominated from the beginning of the season, but influenza B since 11-th week. High risk for influenza A (H1N1) pdm09 group included persons younger than 30 years old and pregnant women (among then influenza was detected in 56.2 % of all cases, whereas influenza А (H1N1) pdm09 - in 65.0 %). Molecular-genetic screening revealed amino acid substitutions in the receptor-binding site of hemagglutinin of strains from two patients (16,7 %). Rapid hospitalization and well-timed antiviral therapy are the main elements of severe forms of influenza and lethality decreasing.