The efficacy of ivabradine use in case of chronic cardiac insufficiency
Article highlites new perspectives of chronic cardiac insufficiency treatmet connected with sinoatrial node f-channels blocker ivabradine use that was fixed during the last years. The results of such large multicenter randomized trials as BEAUTIFUL, SHIFT and others are introduced. The efficacy of ivabradine use in case of chronic cardiac insufficiency with decreased systolic function is convincingly proved there. A special attention is paid to clinical situations, when ivabradine administration is rational in combination with β- adrenoblockers or without them in case of contraindications. The advantages of ivabradine prescribtion in case of combination chronic cardiac insufficiency with obstructive pulmonary disease, diabetes melitus, chronic renal pathology and other comorbid conditions are shown.