MAIN PROGNOSTIC FACTORS AND MICROSATELLITE INSTABILITY IN PATIENTS WITH ENDOMETRIAL CANCER
Occurrence rate of microsatellite instability (MSI) in tumor tissue was studied by means of polymerase chain reaction in 342 patients with endometrial cancer (EC) of stages I IV aged from 30 to 80. Connection between MSI+ tumor phenotype with EC histological structure, tumor localization in the uterus and differentiation degree of the tumor was established, thus allowing to use this index as an additional criterion for EC prognostication.