Humoral immunity in infants with food allergy
Allergen-specific IgG and IgE antibodies were comprehensively studied in 309 infants with food allergy in relation to the severity and duration of atopic dermatitis. The infants with atopic dermatitis showed a high sensitization to the protein of coat's milk and its fractions - casein and β-lactoglobulin. In these infants, an IgE-mediated immune response was predominant, which was present singly or concurrent with allergen-specific IgG antibodies in 68.9%. Food intolerance associated with the formation of isolated blood allergen-specific IgG antibodies was recorded in 39.5% of the infants with atopic dermatitis.