DIURETIC RESISTANCE: CAUSES, MECHANISMS, AND POTENTIALS FOR COPING
The present article is concerned with causes, development and approaches to the coping of diuretic resistance (DR). DR is common presentation sign in patients with severe diseases, for example, in patients with more extreme degrees of nephrotic syndrome or decompensated chronic heart failure. DR always considerably complicates treatment and often leads to worsening of prognosis. It is clear that solution of this problem requires a multidisciplinary approach - the replacement of diuretic and/or increasing the doses only is often ineffective.