Hypofractionated radiation therapy of peripheral non-small cell lung cancer with the increase of the equvivalent summary dose
Radiation therapy of inoperable peripheral non-small cell lung cancer with single daily fraction of 3Gy or 4Gy, 5 fractions per week, up to total dose 60Gy to the primary tumor and up to 39Gy or 45Gy to the regional lymphnodes did not cause severe toxicity in case of limitation of planning treatment volume. 5 year long term local control achieved in a half of the patients which were treated using the mentioned regimen of fractionation due to escalation of total dose by 20-40%. Smaller number of fractions and shorter total treatment time in comparison with traditional fractionation are saving cost of treatment.