Efficiency of early detection methods and optimization of treatment policy for acute destructive pancreatitis
The Article is dedicated to the study of the most informative methods of early detection of acute destructive pancreatitis. The sensibility, specific character and efficiency of applied methods have been defined. A treatment and diagnosis algorithm based on staging and prevalence rate of the process has been developed and implemented into clinical practice. Assessment of efficiency of the algorithm has been carried out based on comparative analysis of patient groups matching by primary parameters during the follow-up period before and after practical application. Standardized approach to selection of treatment and diagnostic algorithm allowed to reduce the intensity of suppurative complications at serious pancratitis from 47,0% to 32,5%, postoperative lethality from 39,6% to 23,1% and general lethality from 33,3% to 15% (p < 0,001).