The role of non-hormonal therapy in treatment of symptoms of the climacteric syndrome
The examination included 60 female patients who previously received hormone replacement therapy for severe climacteric syndrome, aged 48-59 years (the average age 52.2 ± 2.9 years) with the duration of postmenopause 1-10 years (the average time 2.8 ± 2.6 years). The patients referred for medical help due to renewal of climacteric symptoms within 2 months after termination of hormone therapy. All the patients were divided into two groups depending on the duration of hormone therapy: in group 1 (n = 30) hormone therapy lasted for 8-24 months, in group 2 (n = 30) - for longer than 24 months. All the patients received the drug Klimadynon® 20 mg 2 times daily during 3-6 months of the study for cpling with climacteric symptoms that renewed after withdrawal of hormone therapy. The results of the study showed that administration of the drug Klimadynon® containing extraction of Cimicifugа racemosa is an effective method for treatment of moderate and mild climacteric disorders renewing after termination of the course of hormone therapy. Especially important is the possibility of using this phytopreparation in females, whose initial severe condition required long-term (more than 2 years) hormone therapy.