Content of autoantibodies to cytokins in blood serum and lacrimal fluid in patients with type 2 diabetes mellitus in developing nonproliferative diabetic retinopathy
Level of autoantibodies to interleukins in blood serum and lacrimal fluid was studied by ELISA method in 16 patients with nonproliferative diabetic retinopathy (nDR) and in 11 persons without this pathology. Increase of autoantibodies level of IgAs to IL-6, IL-8, IL-10 in lacrimal fluid of patients with nDR was stated. Increase of autoantibodies level of IgG to IL-6 ahd IL-8 in blood serum of these patients was also observed with exception to IL-10 which concentration was practically unchangeable.