COMPARATIVE ANALYSIS CLINICAL, PATHOMORPHOLOGICAL AND IMMUNOHISTOCHEMICAL DIAGNOSIS PRECANCEROUS CHANGES AND CERVICAL CANCER
A histopathological study material and incisional biopsy material after operations of cervical diatermokonizatsii, immunohistochemistry with detection of p16INK4a protein expression in 240 patients with squamous cervical changes in the age of 20-80 years. Revealed cases of discrepancy between the primary histopathological diagnosis and results of subsequent immunohistochemistry results obtained justify the need for adequate and full use of the material taking landmark comparison of data cytological and histological studies and the use of immunohistochemistry or immunocytochemistry the expression of p16INK4a protein and Ki67 proliferation marker in borderline cases.