FORMATION MALFORMATIONS IN CHILDREN WITH CONGENITAL CYTOMEGALOVIRUS INFECTION
CMV infected 0,4–3,5 % of all newborns. The virus has a high potential teratogen, causing the formation of congenital malformations. Aim of this study was to investigate the malformations in children with congenital cytomegalovirus infection. We examined 127 children with СMVI aged 0–3. Found that the structure of congenital malformations is dominated by abnormal development of the CNS with the formation of occlusive internal (18,9 %) and mixed (20,5 %), hydrocephalus, microcephaly (12,6 %), complete or partial atrophy of the optic nerve head (14,2 %), neuro- sensory hearing loss (1,6 %). Malformations of internal organs make up 39,4 %, including heart disease – 13,4 %, bone and cartilage – 7,9 %, urogenital system – 7,1 %, gastrointestinal tract – 11,0 %. Fatal outcome occurs in 61,4 % of children with malformations on CMV background. Surviving children are determined by disabling the traumas of the process in the form of internal occlusion (18,4 %) and mixed (26,5 %), hydrocephalus, microcephaly (18,4 %), cerebral palsy (26,5 %), episindroma (12,2 %), optic atrophy (14,3 %), neuro-sensory hearing loss (4,1 %), CHD (6,1 %), genitourinary malformations (8,2 %) and bone and joint system (6,1 %).