Cellular composition and blood metabolic profile according to AB0 system: grouping, comparative description
The aim of the research is to identify the main trends in blood groups distribution according to AB0 and Rh systems, depending on age, to characterize the change in blood cellular composition and biochemical profile, associated with blood group belonging of the studied. Material and methods. The study involved 2 groups: check one, consisting of 4,988 people, whose average age was 34 ± 3 years and a comparison group of 127 young adults (average age - 19 ± 0.47 years). The blood group was determined according to ABO and Rh system, hematology examination was conducted and metabolic profile was evaluated. Variation of blood cell composition and metabolic parameters, depending on blood group were assessed. The analysis of the results and statistical calculation was carried out using Microsoft Office Excel 2016 Software and IBM SPSS Statictics 23. Results. The obtained data indicate a change of blood groups distribution: A (II) blood group predominates in check group, in the comparison group - O (I). For the first time there were no Rh-negative individuals among AB (IV) blood holders. Biological variations of cellular structure and biochemical profile associated with the blood group of the studied were stated. Conclusion. Blood group is the basis for individual and group biological characteristic features variations, that gives new perspectives for personalized medicine approaches. The features of AB0-system are studied and its contribution to the maintenance of human body homeostasis is an important task for future researches.