NITROZOGLUTATIONI: SPECIFIC SYNTHESIS IN LYMPHOCYTO-ENDOTELIOTCYTIC INTERACTION <i>IN VITRO</i> UNDER CONDITIONS OF CHRONIC IMMUNOCOMPLEXEMIA
The aim of our work was to study the characteristics synthesis of nitrozoglutationi in lymphocytes and endothelial rats with experimental chronic immunocomplexemia and determine corrections influence of corvitini on these processes. Analysis of incubation interaction of lymphocytes and endothelial cells of animals with CIU showed a sharp decrease in GSNO in all test sites (more pronounced in lymphocytes), which can be regarded as a development nitrosoaktivity stress in the studied cells and is a testament to decrease antioxidant system of cells under these conditions. Adding to the incubation medium corvitini — bioflavonoid with pronounced antioxidant and anti-inflammatory properties, led to normalization of all studied parameters.