QUALITY OF PATIENT’S LIFE AFTER MULTIPLE MYELOMA REGRESSION
The aim of this study was to compare the quality of patient’s life after multiple myeloma regression in regard with demographic, clinical, psychosocial risk factors of poor prognosis, depending on the occurrence of cardiovascular events.Materials and methods. The population sample consisted of 95 patients with multiple myeloma. All patients received questionnaires SF-36 and QOL-CS, 89 of them (93.7% of all respondents) have answered questions and have been included in the study. Standard parameters such as life quality, clinical manifestations, previous treatment and demographic parameters have been evaluated by linear regression for factor identification which affect the quality of life.Results. 92 cardiovascular events have been revealed for 1 year in 38 patients, who took part in research (42.7%). Patients with cardiovascular events have observed significantly worse psychological functioning, deterioration of the general health and vitality, reduce of life quality. Previous chemotherapy has been also associated with worse life quality. Patients without cardiovascular events detected the best social functioning comparing to patients with cardiovascular events. Statistical significance of these differences has been achieved only using QOL-CS questionnaire.Conclusion. General health and vitality in patients with multiple myeloma regressions are significantly worse after occurrence of cardiovascular events.