Identification level of sedation depth choice duringdrug-induced sleep endoscopy of upper airways in patients with obstructive sleep apnea syndrome
Obstructive sleep apnea syndrome causes serious social and medical problems and requires complex treatment. Right choice of surgical and conservative treatment depends on exact diagnostics ofall obstruction levels. Drug-induced sleep endoscopy of upper airways allows determining levels of drug-induced apnea. The problem of adequate level of sedation depth still remains unsolved, despite of long-term experience. Frequent breathing arrests at night lead to unpredictable violation of sleep architectonics, often with complete reduction of deep phases. Patients may report both superficial alone or superficial and deep sleep phases at night regardless of disease severity. It means that recommended level of sedation BIS 50-70% does not guarantee achievement of necessary degree of reticular formation depression, when a certain patient will have respiratory events during sleep, and may lead to too superficial or deep sedation. The analysis of automatic hypnogram and electroencephalographic data during nocturnal polysomnography will allow substantiating the choice of sedation depth and implementing personalized approach in drug- induced sleep endoscopy of upper airways. Obtained endoscopic data will correspond to upper airways’ obstruction during sleep.