Changes in perilymph composition in gentamicin intoxication and ways of its correction
Diagnostically significant prognostic laboratory indicators of sensorineural hearing loss in the blood of children treated with aminoglycoside antibiotics were identified. It was established that in blood of children with gentamicin intoxication the content of malonic dialdehyde medium molecular weight peptides significantly increased and the activity of superoxide dismutase decreased. The effectiveness of prevention introduction of Phosphogliv together with aminoglycoside antibiotics in children with a risk of sensorineural hearing loss development was found.