Features of clinical, functional and metabolic status of children with obesity at different age
Material and methods: a comparative study of clinical, functional and metabolic status of 147 children of the age group from 7 to 18 years with primary obesity was conducted.Results: even distribution of excessive deposition of fat tissue is typical for children at the age of 7-10. Metabolic status analysis showed that only 15% of children had changes of the serum lipid profile. Frequencies of metabolic disorders (glucose tolerance and insulin resistance disturbances) in the group of 11-14 year-old children were associated with the percentage of body fat mass (r = 0,37 and r = 0,30). 15-18 year-old adolescents had two clinical and pathogenic types of the disease. The first was characterized by the development of stable arterial hypertension on the backdrop of moderate metabolic disorders in the blood. The second type of disease was characterized by pronounced metabolic changes with hyperglycemia and hypercholesterolemia in 33% of adolescents (p = 0,04, p = 0,04), hyperinsulinemia in 45% (p = 0,041) and labile hypertension in 33% (p = 0,001).Conclusions: prevention measures for the disease should be taken at the age of 7-14, because in 15-18 year-old group the obesity is associated with more pronounced clinical and pathogenic disorders.