PSI FEATURES IN PATIENTS WITH MAXILLOFACIAL PATHOLOGY
Background . At the present time, acute is the problem of nosocomial purulent-septic infection (PSI), aggravating the course of the underlying disease, increasing the length of stay in the hospital. The main role in the occurrence of complications in the department of oral surgery belongs to endogenous purulent-inflammatory diseases, which account for 80.8 % of all hospital-based PSI. The study of the microbiological spectrum and the nature of the antibiotic resistance of the etiological agents of the PSI in the conditions of the separation of the oral surgery of the multidisciplinary hospital will make it possible to develop recommendations for conducting empirical etiotropic therapy of PSI. Materials and methods . A retrospective analysis of 104 case histories of patients in the department of oral surgery for 2016, among them 55.77 % of men and 44.23 % of women. The studies included a bacteriological analysis of isolates obtained from patients and a determination of the antibiotic susceptibility spectrum of isolated cultures. Results . As a result of the study, it was found that among the complications of the maxillofacial region there was a root cyst, acute odontogenic osteomyelitis, phlegmon and abscess of the oral cavity. The isolates obtained are mainly Gram-positive microorganisms. It was established that among the gram-positive etiologic agents of purulent-inflammatory infections of the maxillofacial region the representatives of the genera Staphylococcus prevail 23.08 %, Streptococcus 38.46 %. According to our data, most strains of dominant species are sensitive to aminoglycoside and tetracycline groups. Penicillins and macrolides show much less therapeutic effectiveness. Conclusions . PSI are the most common complications in patients with pathologies of the maxillofacial region. The etiological agents of PSI in patients with pathologies of the maxillofacial region are mainly gram-positive microorganisms represented by genera. Staphylococcus and Streptococcus. For antibacterial therapy in the department of oral surgery for patients, it is rational to use preparations of the group cephalosporins, aminoglycosides and tetracyclines.