The course of pregnancy early life at women with dysfunction of hypothalamus
Carry out comprehensive survey of 98 pregnant women with hypothalamic dysfunction (DH), and 20 pregnant women without endocrine disorders. At women with DH pregnancy is on the background of metabolic disorders, as insulin resistance – 15,3%, for gestational diabetes – 11,2%, hyperlipidemia and/or dyslipidemia – 70,4%. On the background of metabolic changes disorders trophoblast invasion, which is confirmed decline endocrine function of trophoblast. Pregnant with DH are at risk for reproductive losses in early pregnancy, the development of primary placental failure, require predgravidar preparation with correction of metabolic disorders.