Evaluation of cell turnover and mucin-producing activity of the epithelium of the gastric mucosa infected with Helicobacter pylori
In biopsy specimens of gastric mucosa children infected with HP, in epithelial cells indicated an increase in the rate of cell turnover, as well as redistribution of zones of proliferation and cell death in functional departments mucosa compared to uninfected children, especially when infected with cagA (+) and babA2 (+) strains HP. The distribution MUC5AS in the gastric mucosa of infected do not differ from that in biopsies from non-infected children, whereas the production of MUC6 in HP infection is observed only in the basal parts of the glands.