Modern directions of the molecular genetic analysis application in the diagnostics of rheumatic diseases
The use of molecular genetic methods in rheumatology has opened up new possibilities for the study of multifactorial nature of rheumatic diseases as the most common chronic diseases of humans, which lead among the reasons of permanent disability. Molecular genetic techniques have a significant role in establishing of probable infectious etiology of rheumatic diseases with the predominant value of individual genetic characteristics over the contribution of environmental factors in the determination of rheumatic diseases is shown. One of current trends of molecular genetic testing application in rheumatology is the identification and study of candidate genes. The study of molecular-genetic profile heterogeneity will improve the rheumatic diseases pathogenesis understanding, analyze the disease severity and selecting treatment tactics and also can be used to categorize these patients.