Endogenic intoxication syndrome in pathogenesis of the opioid withdrawal status under conditions of using lymphotropic technics
The present article is dedicated to the assessment of detoxification effects of interosseal lymphotropic injections (IOLI), lymphotropic sorption and lymphotropic ozone technics in pathogenesis of acute and sub-acute stages of the opioid withdrawal status. 201 patients were distributed in to 4 homogenons groups. The comparison group received a standard therapy; the main first group was treated with IOLI in addition to the standard treatment, the second main one was treated with the IOLI complex and enterosorption, the third was treated with the IOLI complex and ozone therapy. Patients were examined on the 2nd and 8th days of the treatment. It was shown that when using a standard therapy, the desinhibition of detoxification processes in the organism acquires a pathogenetic significance which in combination with overexertion of renal and immune parts of the natural detoxification system leads to the generalization of endotoxicosis and disturbances in the recovery process. The IOLI detoxification effect was confirmed by the restriction of the pathogenetic significance of the endogenic intoxication syndrome and preservation of the functional reserve of the organism natural detoxification system. The lymphotropic sorption and lymphotropic ozonic technics ensured a substantial enhancement of the organism detoxification in pathogenetic and non-specific directions and accelerated the convalescence process by repairing the barrier filtration function and stimulating the immune function of the lymphatic system.