New allele A*24:314 for the loci HLA-A identified in populations of the Northern Caucasus
Sequence based typing was used to identify human leukocyte antigen HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA- DQB1 alleles from 2444 donors residing in the Chechen Republic and the Republic of Dagestan, Russia, for unrelated hematopoietic stem cell registry. During the performance of the research in the study population there was identified new allele, which was not previously registered on The WHO Nomenclature Committee for Factors of the HLA System. In this population, 51 HLA-A alleles from 19 groups of alleles were detected. Alleles occurred with the frequency more than 10% included HLA-A*02:01 (32.28%), 01:01 (11.54%), 24:02 (10.84%). New identified allele HlA-A*24:314 (0.31%) ranks second in the frequency of alleles among the allelic group A*24, after allele A*24:02.