CLINICAL, NEUROLOGICAL AND NEUROPHYSIOLOGICAL ASPECTS OF PARKINSON'S DISEASE AND CHRONIC BRAIN ISCHEMIA WITH PARKINSONIC SYNDROME
The aim of the research is to study the clinical, neurological and neurophysiological features of Parkinson’s disease and chronic cerebral ischemia with Parkinsonian syndrome. The authors analyzed the outpatient records of 22 patients aged 43 to 78 years. The first group consisted of 7 patients diagnosed with Parkinson’s disease, the second group included 15 patients with chronic cerebral ischemia with Parkinson’s syndrome. It was revealed that in the group with Parkinson’s disease, the patients were younger and had a more pronounced insufficiency of the cholinergic system of the central nervous system. EEG - indicators characterizing the activity of the dopaminergic system were reduced in both groups. Inclusion of selective dopamine receptor agonists and glutamate receptor blockers in therapy increases the proportion of favorable CNS reactions in patients of both groups.