ANALYSIS OF THE EFFICACY OF THE TREATMENT OF ARTERIAL HYPERTENSION BY NIFEDIPIN OF DURABLE ACTION
We investigated 67 patients with COPD in exacerbation with episodes of high pressure. Initial examination included 24-hour arterial pressure (AP) monitoring, echocardiography with estimation of mean AP in pulmonary artery and investigation of external respiratory function. According 24-hour AP monitoring we received, that 46 patients had significant data of mild arterial hypertension (AH) during of night period. These patients were deviated into two groups. First group in addition to the traditional therapy of COPD received a cordaflex - retard 20mg twice a day. Second group is treated by traditional therapy only. In 10 days we made a repeated 24-hour AP monitoring, echocardiography and investigation of external respiratory function. The data showed that in patients of the first group in comparison with patients of the second group, decreasing indices of the daily profile of AP, the level of pulmonary hypertension became significantly lower. The change in external respiratory function distinguished doubtfully.