DEVELOPMENT method of INCREASING viability FOR NEWBORN lambs using nanobiomaterials
The effective way to improve viability of newborn lambs using nanobiomaterials which was created based on a comprehensive drug «Caplaestrol + OV Zn», which provides normalization of homeostasis and improve the structure of placenta and fetus under development by streamlining the state of prooxidant-antioxidant and oxygen metabolism. Specifically normal content in serum vitamin A, zinc and total protein; prooxidative-antioxidant system containing serum malondialdehyde, catalase, superoxide dismutase and erythrocyte malondialdehyde, catalase, reduced glutathione and oxidative-antioxidant value; system state oxygen metabolism - the number of erythrocytes and hemoglobin concentration of 2,3-bisphosphoglycerate. Compared with the control group increased weight of newborn lambs to 374,5 g (11,7 %, P < 0,99), litter weight - 22,6 g (8,6 %, P < 0,999), the area of the placenta - 30,4 cm<sup>2</sup> (8,7 %, P < 0,99) and the number cotyledons - 3,8 (4,6 %, P < 0,99). In the long term expected testing other drugs that are based on nanobiomaterials, in order to reduce the cost and simplify the methods of their application.