THERAPY OFAFFECTIVE DISORDERS IN OPIOID ADDICTED PATIENTS, AT THE REHABILITATION STAGE
The work purpose is to define possibilities of therapy of affective disorders in opioid addicted patients, at the rehabilitation stage. It is surveyed 176 opioid addicted males, with depressions of different severity level after detoxication: 97 persons (the basic group) in the conditions of orthodox rehabilitation centre, during three months received antidepressive pharmacotherapy (cytalopram 40 mg per day) and 79 persons (control group) passed a rehabilitation course without pharmacotherapeutic supports. By sevenfold researches during one-and-a-half-year rehabilitation course (on 0, 10-th, 30-th, 90-th, 180-th, 360-th and 540-th days from the moment of the end of detoxication) the dynamics of the affective status of patients was estimated with use of scale Hamіlton-21; and also the influence of antidepressive therapy on adherence of patients to the rehabilitation program was defined by construction “ survival curves” Kaplan-Meyer. It is shown, what even rather short course of antidepressive therapy in opioid addicted patients, essentially accelerates return development of depressive symptomatology; and also strengthens adherence of patients of this category to rehabilitation. (The Journal of Psychiatry and Medical Psychology. - 2012. - № 3 (30). - P. 76-81).