Determination of tactics for the treatment of patients with chronic cystitis complicated by bladder leukoplakia
Chronic cystitis is one of the most common urological diseases, affecting more than 100 million people worldwide every year. Bladder leukoplakia, as a complication of chronic cystitis, is still a completely unexplored disease of the bladder mucosa. In the light of modern research, leukoplakia is a pathological process that is characterized by a violation of the main functions of the stratified squamous epithelium: the absence of glycogen formation and the occurrence of keratinization, which is normally absent. Leukoplakia is a common pathology in treatment-resistant chronic cystitis. As noted earlier, with the development of leukoplakia, the properties of the mucosa change, which can lead to violations of its protective properties - the site of leukoplakia can promote adhesion and subsequent colonization of the bacterial flora. It is due to this mechanism that additional conditions are created for frequent exacerbations of cystitis. It is believed that surgical methods should be carried out only if the conservative therapy is ineffective. The aim of the work is to compare the effectiveness of conservative and surgical methods for the treatment of chronic cystitis complicated by bladder leukoplakia.