The mechanism of neuroprotective effect of diod-laser (810 nm) transpupillary thermotherapy of optic nerve head at glaucomatous optic neuropathy. Review
The review of literature describes mechanisms of neuroprotectiveeffectoftranspupillarythermotherapy (TTT) of optic nerve head at glaucomatous optic neuropathy. The mechanism of neuroprotective effect of TTT caused by biostimulating effect of low-energy laser radiation and arising under the influence of ТТТ a hyperthermia on biostimulating effect of low-energy laser emission and hyperthermia, arising after TTT. Hyperthermia leads to local vasodilatation in the field of laser emission and to improvement of microcirculation and tissue trophism. Also a synthesis of heat shock proteins has been under hyperthermia. Heat shock proteins improve the cell's capability to resist stress, protect retinal ganglion cells from damaging agents. An application of transpupillary thermotherapy of optic nerve head is pathogenetic grounded in patients with glaucomatous optic neuropathy.