ATOPOBIUM VAGINAE IN THE VAGINAL MICROBIOME OF PREPUBERTAL GIRLS
The aim of the study was to investigate the role and place of Atopobium vaginae in the vaginal microbiome in prepubertal girls both in health and in the presence of vaginal dysbiosis at the present stage. We observed 174 prepubertal girls, who were divided into two groups: the main group O (n = 134) with the presence of vaginal dysbiosis of different degrees, and the control group, represented by 40 girls with normal vaginal microbiome and the absence of any clinical manifestations of vaginitis. Investigation of vaginal microbiome spectrum was carried out using a complex quantitative PCR in real time using the test-system "Femoflor-16" (Russia). It was established that in the vaginal microbiome of prepubertal girls opportunistic pathogens of occurs in health in 7.50% of cases, in vaginal dysbiosis - in 41.04%. In the majority of cases the Atopobium vaginae combined with the presence of Gardnerella vaginalis / Prevotella bivia / Porphyromonas spp., and is a bacterium associated with vaginal dysbiosis in prepubertal girls.