STUDY OF ASSOCIATION OF PAROXYSMAL ATRIAL FIBRILLATION WITH REPRODUCTIVE AGING IN WOMEN
A study connection between paroxysmal atrial fibrillation (AF) with reproductive aging plays an important role in cardiology and gerontology. At present time, it has been revealed that atrial fibrillation increases with a psychological likelihood of onset and frequency of paroxysms. Some authors consider that studying of electrocardiographic, electrophysiological and hemodynamic predictors and increased frequency of AF in different stages of reproductive aging in women for development adequate methods of treatment and prevention of heart rhythm disturbances. The aim of this work was to study nature of structural and electrophysiological changes in the heart in AF at the stages of reproductive aging in women. The study involves 118 women with frequent paroxysms of AF, who were divided into three groups. 1st group includes 35 patients with AF developed at the stage of reproductive period; 2nd group includes 45 patients with paroxysms AF developed at stage of menopause approaching; 3rd group includes 38 people when AF developed during postmenopause. The study includes ECG recording, 24-hour ECG monitoring, transesophageal electrophysiological study of the heart, and echocardiography. Significant and regular increases in the size of the left atrium, the atrioventricular ratio, as well as a decrease in a frequency of a maximum point of arrhythmia induction, an effective refractory period of the left atrium, an increase in the time of paroxysm induction and maximum atrial response at the stages of reproductive aging in women were revealed. Data shows dependence in a frequency and duration paroxysms of AF with reproductive aging in women.