DIFFERENTIAL DIAGNOSTICS OF CEREBRUM TOXOPLASMOSIS AND TUBERCULOUS MENINGOENCEPHALITIS
Cerebral toxoplasmosis and tuberculous meningoencephalitis are the most widespread opportunistic infections of the central nervous system in HIV-infected patients with advanced immunosuppression. Differential diagnostics of cerebrum toxoplasmosis and tuberculous meningoencephalitis are difficult because similar clinical picture, frequent combination of active tubercular process and toxoplasmosis, simultaneous development of other opportunistic infections, inaccessibility for patients of modern radiological methods of revealing. Taking into account the own examinations of patients suffered from HIV-associated tuberculous meningitis, who were treated in the Donetsk republican clinical hospital, and literary data about the clinical features and diagnostics of cerebral toxoplasmosis, presented by medical establishments, we have selected the most informing and accessible criteria of differential diagnostics, based on distinctions of a clinical picture, composition of spinal fluid, level CD4-cells and МRT cerebrum imaging. Algorithms for diagnostics of both diseases were offered.