RELATIONSHIP THERAPY IN EFFECT METABOLITOTROPNOYI HYPERTENSION ASSOCIATED WITH INSULIN RESISTANCE, ON THE EXCHANGE INDEX CARBOHYDRATES AND HOMA-IR
Hypertension (HT) is 25-30% of the adult population of developed countries, including Ukraine. In the last 10-15 years there has been increased interest in metabolic disorders in hypertension. According to most experts, the leading factor in the formation of symptom of metabolic syndrome is insulin resistance (IR). In the development of hypertension in leading IP value has a complex effect of hyperinsulinemia (GI) and associated metabolic disorders. The article presents data on the impact their metabolitotropnyh drugs (rosiglitazone and Tioté-ryazolinu) that were included in the standard antihypertensive pharmacotherapy (candesartan perindopril +), the state of carbohydrate metabolism. The most significant impact on IP in hypertensive patients allows the inclusion of a combination of perindopril + candesartan rosiglitazone and Thiotriazoline, shown greater reductions in blood glucose fasting and glucose 2 hours after a glucose load, especially index HOMA-W, the value which was statistically (p < 0.05) higher than in other groups of patients.