RISK ASSESSMENT OF CONTRAST-INDUCED NEPHROPATHY IN PATIENTS WITH ACUTE CORONARY SYNDROME
Aim. The aim of the study was to estimate the incidence and risk factors of contrast-induced nephropathy in patients with acute coronary syndrome hospitalized in Cardiology Department № 1 of the City Clinical Hospital № 7, Kazan. Material and methods. Clinical and laboratory parameters were assessed in 565 patients with acute coronary syndrome, patients’ age ranged from 30 to 95 years [mean age was 65,78±11,41]. All patients were assessed for their medical history, coronary angiography protocols, and the findings of general and biochemical blood tests. All patients were calculated the glomerular filtration rate according to CKD-EPI formula and the risk of contrast-induced nephropathy according to Mehran scale (2004). Results and discussion. After coronary angiography, 89 (15,8%) patients developed contrast-induced nephropathy; The incidence of contrast-induced nephropathy in patients with acute coronary syndrome is rather high and, according to our data, reaches 15,75%. Conclusion. The most significant factors associated with the development of contrast-induced nephropathy in patients with acute coronary syndrome are: age (over 75 years), anemia, hypertension, history of chronic kidney disease, a history of myocardial infarction, reduced ejection fraction below 55%, early postinfarctional complications, and multivessel coronary lesions.