Rational treatment of psoriasis
Psoriasis is a chronic dermatosis with mainly a genetic determinant that causes the immunopathological reactions. These may develop into benign hyperproliferation of epitheliocytes and its differentiation and keratinization malfunction. The reaction may also produce pathology of organs and systems. There are various approaches to treating psoriasis medically: anti-inflammatory and disintoxication cures, symptomatic therapy, drugs that suppress proliferation and differentiation of keratinocytes. The efficiency of psoriasis treatment rises when a combination of different methods (such as drugs, physiotherapy and phototherapy) is used. Photo-chemotherapy is one of the most effective up-to-date methods of psoriasis treatment. Patients take photosensitizing preparations before the procedure starts. In Russia Ammifurin is produced in Russia, it is prescribed at a rate of 0.8 mg per 1 kg of body weight. Another modern method of photo-chemotherapy is PUVA-baths: first the patient takes a general or local Ammifurin water-solution bath (using the preparation's 0.3% alcohol solution) and then gets long-wave UF irradiation. The tactics of psoriasis treatment depend on the form, stage, extent of skin rash appearance and its nature and on a patient's general health.