THE ANTITUMOR EFFECT OF EXPRESSION PLASMID BEARING DUSP9 GENE IN SHR MICE HAVING SOLID EHRLICH CARCINOMA
SHR mice with Ehrlich carcinoma were used to assess the effects of administration of a newly developed plasmid DNA construct bearing DUSP9 gene. The construct has been found to inhibit Ehrlich tumor growth by promoting necrosis. The administration of the construct has been shown to decrease the prophase index suggesting the attenuation of Ehrlich tumor malignancy.