HYPERBARICAL OXYGENETION AS THE OPTIMAL FACTOR OF ARTICULAR CARTILAGE STRUCTURE OPTIMISATION IN OSTEOARTHROSIS ASSOCIATING WITH IMMOBILAZE OSTEOPOROSIS (EXPERIMENTAL STUDY)
The knee cartilage of non-loaded leg with immobilized osteoporosis was investigated on laboratory rats of Wistar line (n = 70). Immobilized osteoporosis was modeled by amputation of shin of one of two back lags of the rats. After amputation the laboratory rats could not load those lags. All morphological signs of immobilized osteoporosis were defined in operated lags after 90- 100 days. The absence of functional loading of the legs led to generation and destruction of the articular cartilage similar to typical changes of them at osteoarthrosis. Morphological facts showed that immobilized osteoporosis and osteoarthrosis in damaged legs are forming simultaneously. Employment of the hyperbaric oxygenation in soft regime reduces the expression of pathological changes in the knee cartilage, provides their regress, improves structure of the cartilage, making them closure to the standart.