Metabolic homeostasis in patients with climacteric syndrome on the background of hormonal therapy
The article presents the results of examination and treatment of 128 patients with climacteric syndrome. The efficacy of HRT in coping with the symptoms of climacteric syndrome (CS), dynamics of changes of metabolic parameters of blood on the background of its various regimens and duration were assessed. The evidence was obtained not only about the efficacy of HRT in treatment of CS, but also about a significant protective effect of HRT on the values of metabolic homeostasis irrespective of a hormonal drug used as compared with the control group (without HRT). In patients of the basic group on the background of HRT no increase of the body weight or formation of visceral obesity was noted, which was observed in women from the control group. Therefore, the role of HRT in prevention of menopausal metabolic syndrome that increases a risk for cardiovascular diseases has been shown.