The morphological changes of regional lymph nodes after combination of the chemotherapy with the immunotherapy in treatment of cervical cancer patients
By the method of a light microscopy it was studied the structural organization of the common ileal lymph nodes (ILN) among patients suffered from cervical cancer (CC) without metastasises after inclusion of immunomodulator in the chemotherapy. The chemotherapy at СС leads to sclerosis transformation of cortical and medullar zones of ILN. Dynamics of their cellular structure reflects as death of the active immunocompetent cells under the influence of cytostatic and also an inactivation and an elimination of a tissue debris at a necrosis and destruction of a tumor in the region of a lymph collection and development of sclerosis processes after a chemotherapy. The immunotherapy promotes restitution of mitotic activity of cells after chemotherapy, but does not reduce their death from effect of cytostatic and expressiveness of a sclerosis.