CLINICAL AND IMMUNOLOGICAL EVALUATION OF LOCAL APPLICATION EFFICIENCY OF 8% CHITOSAN ASCORBATE IN COMPLEX TREATMENT OF PATIENTS WITH GENERALIZED PERIODONTAL DISEASE
Background. The aim of the work is to study the results of clinical and immunological evaluation of local application efficiency of 8 % chitosan ascorbate in complex treatment generalized periodontal disease. Materials and methods. The authors studied the index indicators of periodontal tissue condition of patients with chronic generalized periodontal disease of light and moderately severe form in dynamics of the disease treatment by the traditional aaproach and using a gel-like preparation of 8 % chitosan ascorbate. Results. The clinical and immunological research undertaken by the authors confirms the medicinal effect of 8 % chitosan ascorbate determined by prolonged sanitation of periodontal pockets due to antibacterial activity of chitosan and its immunotropic influence on effectors of innate and adaptive immunity. Conclusions. The article demonstrates the expediency of application of this preparation in a complex of medications at the stage of preoperative preparation, postoperative period and as a medication of supporting therapy of generalized periodontal disease.