Comparative analysis of preovulatory follicle vascularization in polycystic ovarian syndrome during controlled induction ofovulationandevaluationoffactorsinfluencingitsimplementation
There was made the estimation of preovulatory follicle hemodynamics using three-dimensional power Doppler ultrasound in controlled induction of ovulation in treatment of infertility in women of late reproductive age with polycystic ovarian syndrome. The basic factors related to ovulation were identified. It was found that late reproductive age patients with polycystic ovarian syndrome in controlled induction of ovulation using human urinary gonadotropins with ovulation perfusion in preovulatory follicle do not differ from that of healthy women with natural ovulatory cycles. In the absence of ovulation, the vascularization of а preovulatory follicle is significantly reduced statisti- cally in comparison with healthy women with natural ovulatory cycles. There were found statisti- cally significant positive correlations between average diameter of preovulatory follicle and volume of preovulatory follicle in all groups; between perfusion indices in preovulatory follicle (VI-FI, VI-VFI, FI-VFI) in patients with polycystic ovarian syndrome during the induced cycle with or without ovu- lation. There are 3 factors that may be associated with the presence (lack of) of ovulation that are presented in the order of their clinical relevance: ultrasonic characteristics of preovulatory follicles (average diameter, volume); perfusion of preovulatory follicle (VI, FI, VFI of preovulatory follicle) and ultrasonic characteristics of endometrium in preovulatory period (thickness of endometrium in pre- ovulatory period).