Regional Features of Pathogens of Newly Diagnosed Community-Acquired Urinary Tract Infections in Infants and Small Children
Study Objective: to analyse features of species composition of urinary tract infection (UTI) pathogens in out-patient settings in infants and small children; to assess their antibiotic susceptibility and future therapy prospects for bacterial urinary infections. Study Design: open prospective study. Materials and Methods. Analysis addressed results of bacteriological urinary tests in 106 children with UTI at the age from one month to three years, and pathogen antibiotic susceptibility. Study Results. Positive bacteriological urinary test results were recorded in 82 (77.36 ± 4.06%) observations. 8 microorganism species were identified. Major UTI pathogens in infants and small children are Enterobacteriaceae spp., primarily E.coli (45.12 ± 5.49%). Conclusion. It is worth mentioning that recently UTI pathogens have become more versatile; a share of microorganisms which were previously not typical for this group of patients, e.g. Pseudomonas aeruginosa and Candida, has increased. All uropathogens detected in bacteriological urinary tests preserve high susceptibility to amoxicillin/ clavulanic acid, II and III generation cephalosporins. Enterobacteriaceae spp. resistance to ampicillin is still high. The data on the composition and susceptibility profile of uropathogens in primary UTI in infants and small children should be taken into account when selecting initial empiric antibiotic therapy in out-patient setting in Primorski Krai.