Studies on the course of nonerosive forms of gastroesophageal reflux disease in patients with duodenal ulcer after Helicobacter pylori eradication
Effects of eradication therapy at the course of accompanying gastroesophageal reflux disease (GERD) in patients with duodenal ulcer (DU) has not been studied well enough yet. The course of nonerosive forms of reflux disease after successful eradication was studied in 51 patient. In the control group there were 27 patients with ineffective eradication therapy. The study performed has shown that the successful eradication therapy in patients with duodenal ulcer had resulted in the reduction and disappearance of UD clinical symptoms in 56.8% of cases. The incidence of GERD erosive forms was similar both in the studied and control groups. It indicated that eradication therapy had not any effects at the development of erosive esophagitis. 3-year follow-up of patients with developed erosive esophagitis after successful eradication therapy has shown that in 70% of cases esophageal erosive lesions disappeared without any treatment.