ASSESSMENT OF RISK FOR HEALTH HAZARD IN PETROCHEMICAL PRODUCTION WORKERS EXPOSED TO CHEMICAL FACTOR
Aim. The aim of the study was to assess the changes in a number of hematological and biochemical indices among workers of petrochemical production in response to exposure of a chemical factor. Materials and methods. Hygienic studies on assessment of conditions of work were carried out in the working zone of petrochemical production workers and included hygienic assessment of industrial environment and working process according to R 2.2.2006-05. To study the indices of workers’ hemostasis the following clinicolaboratory methods were used: general clinical analysis, biochemical study of functional status of the hepatobiliary system with determination of indicator enzyme activity, total bilirubin and its fraction content and thymol test, as well as investigation of lipid metabolism with estimation of total cholesterol (TC), alpha-cholesterol, triglyceride (TG), low-density lipoprotein cholesterol (LDLC), atherogenic index (AI). Results. The results of biochemical study indicated chronic exposure of chemical factor. Conclusions. The key harmful factor of industrial environment in repairmen is air pollution of the working zone with chemicals exceeding the allowable value by 1,5-8 times. Changes in a number of clinicolaboratory indices, which are comparable with the level and character of biological effect of harmful substances, were revealed among repairmen.