COMPARATIVE PHYTOCHEMICAL STUDY OF THE AERIAL PARTS OF THE WILD-GROWING AND CULTIVAT-ED CHICORY ORDINARY (CICHORIUM INTYBUS L.)
The search for new plant species that are promising for use as a source of biologically active substances is an actual area of scientific research in the field of chemistry of natural compounds. The object of this study is the chicory (Cichorium intybus L.) The purpose of our scientific research is to conduct a comparative phytochemical study of the aerial parts of wild-growing and cultivated chicory to establish differences in the qualitative composition and content of secondary metabolites. As a result of studies by HPLC-MS, in the aerial part of a wild-growing plant, 10 compounds were identified esculletin, chicoriin, chicoric acid, chlorogenic acid, kaftaric acid, isochlorogenic A acid, caffeic acid, isoquercetin, astragalin, rutin. The dominant group of substances are oxycoumarins. The phenolic complex of the cultivated plant has a similar composition of secondary metabolites, however, its derivatives are hydroxycinnamic acid derivatives. The quantitative content of phenolic compounds in the wild-growing chicory herb was 2.56±0.12%, cultivated - 4.14±0.21%. Significant differences in the content and qualitative composition of phenolic compounds make it possible to use the chicory of a wild-growing and cultivated population to obtain pharmaceutical substances with various pharmacological effects.