Vessel-due f in the prevention of thrombophiс complications of expectant mothers with defects of hemostasia
The main purpose of the work is research of the effectiveness of Vessel-Due F use like the prevention of grave complications of gestational process of the patients with different forms of thrombophilia. 105 patients in 2 and 3 trimester of pregnancy were inspected. With the help of simple randomization by the methods of 2 envelopes all patients were divided into 2 groups: main group(74 expectant mothers with high level of risk in development of perinatal complications in gestational process with Vessel-Due F therapy) and the group of comparison (31 patients with traditional therapy only). As a result of research the following regularity was noted: significant reduction of the index of the activity of lupous anticoagulant and activation of fibrinolytic activity after the two-week use of Vessel-Due F in the dose of 1000 units per 24 hours (p<0,02, effectiveness 85%), improvement of bloodstreams in uteroplacental and fetalplacental course (p<0,03, effectiveness 77%). Moreover, it was determined, it is better to prolong the prescription of the preparation to the point of the delivery and during puerperal period. It does not increase the level of hemorrhage after the delivery, but effectively prevents thrombosis during the pregnancy, generic and operating stress of patients with defects of hemostasia.