POSSIBILITIES OF THE SECTRETOLITHIC AND SECRETOSTIMULATING THERAPY OF EXODUSIVE RINOSINUSITIS
High incidence of rhinosinusitis in our country and abroad, their transition to a chronic form, recurrence determine the urgency of the problem of treatment of this pathology. In this regard, and the need for drug treatment of this category of patients is increasingly rising. The possible mechanisms of inflammation of the nasal mucosa indicate the advisability of using local anti-inflammatory, secretolitic and secreting stimulating therapy. The promising drugs in this area include Sinuforte, extracted from Cyclamen europaeum. In the clinic of otorhinolaryngology Voronezh State Medical University analyzed the effectiveness of the endonal application of Sinuphorte in the treatment of acute exudative rhinosinusitis in 40 patients aged 19 to 52 years: 23 women and 17 men. Patients received the drug according to the manufacturer's recommendations: 1 dose in each half of the nose 1 time per day for 8 days. In all patients receiving secretionolytic, secreting-stimulating therapy, positive results were achieved. The clinical effect of the treatment in the patients of the main group with the catarrhal sinusitis occurred on average in 4 days. Disappeared pain, significantly improved nasal breathing, completely disappeared inflammatory changes in the nasal cavity. In the control group, the positive dynamics of the clinical picture of the disease was noted 2-3 days later. In the main group of patients with a purulent form of sinusitis, the regression of the disease was observed after 6 days, in the control group - 3-4 days later. The data obtained from clinical, radiologic and morphological studies indicate the high effectiveness of Sinuphorte in the treatment of acute rhinosinusitis and allow it to be recommended for wider use as monotherapy in catarrhal processes and in combination with systemic antibiotics for purulent inflammation of the nasal mucosa and paranasal sinuses.