Pathomorphological charachteristic of new born placenta with ultrasound marker of insufficiency
The abnormality of placenta's morphology associated with the development of placental insufficiency. Fetal status is depends on the safety and feasibility of compensatory-adaptive reactions of the placenta in response to violation of utero-placental blood flow. In the absence of this condition, activated involutive - degenerative processes that lead to the deposition of fibrinoid and calcium in ischemic areas in fetal organs and placenta itself. Aim. Comparison of placentas' morphological and functional features of newborns with echogenic intracardiac focuses and in the absence of them. Materials and methods. Histological study of 64 placentas at term and preterm neonates: 32 - neonates with echogenic intracardiac focus and 32 - without studying ultrasound marker. Results. No differences in placental - fetal index in groups of children with the presence of the echogenic intracardiac focus and without it. Acute hypoxia does not affect the formation and preservation of the echogenic intracardiac focus. For placentas of newborn with echogenic intracardiac focus is characterized by impaired maturation and vascularization of the villus, the consolidation of syncytial knots, the presence involutive - degenerative reactions in the form of excess calcium deposits in the villous chorion, which reflects mainly compensated chronic placental insufficiency. Antenatal infection of the fetus in combination with chronic feto - placental insufficiency increases the risk of keeping «echogenic intracardiac focus' after birth. Conclusion. Echogenic intracardiac focus is one of the ultrasound markers of non-specific placental disorders.