CLEARANCE OF SOLUTE FREE AND SODIUM FREE WATER: CLINICAL SIGNIFICANCE
Data of diseases accompanied by change of blood serum osmolality are presented, states with a combination of hyponatremia with hyperosmia are characterized. There are presented estimation varieties of renal response to a change of blood volume and extracellular fluid at a change of its osmolality and Na+ concentration. Clinical significance of clearance calculation of solute free water and of the sodium free water is shown. Factors of different reactions of body regulatory systems on hyperosmia caused by hyperglycemia, uremia, or hypernatremia are discussed.