Stiff-person syndrome with early onset in infancy
The case of stiff-person syndrome with benign course in 16-years old patient is presented. The initial clinical signs of the disease were observed in in- fancy with retarded development of motor functions and skeleton muscle lumps. The diagnosis was made using generally accepted clinical and electro- myographical criteria. Aspects of differential diagnosis, pathogenesis and clinical course polymorphism in early-onset cases of the disease are discussed.