ETIOPATOGENEZ OBSTRUCTIVE UROPATY AT CHILDREN
275 children with congenital obstructive uropatiya, from them 93 patients with congenital uretero gidronefrozy and 182 children with congenital the gidronefrozy are surveyed. The age of patients made from 2 months to 15 years. In work results of bacteriological research of urine, in time operational intsizionny and biopsy materials of a kidney parenchyma and local urethral, site -urethral segments, and also changes of various links of immune system in urine are studied and compared among themselves. The conducted research proves that the reasons of the obstructive uropaty a leading to a sclerotic factors of renal fabric, activation of various factors of inflammatory process, migration of cages of immune system and to abnormal synthesis sitocin, are congenital dysplastic changes of a wall of a urethr and a kidney parenchyma. Urodynamic dysfunction leads to inflammatory changes in an interstitial with the subsequent progressive decrease in kidney junctions, and in this quality to development nefroskleros.