Endothelial function and pulmonary heamodynamic in patients with COPD
Endothelial function and pulmonary haemodynamic in patients with COPD. Gichkin A., Lukina E., Perley V., Alexandrov A., Kuzubova N. Summary: A chronic obstructive pulmonary disease (COPD) is one of the important problems of public health services in the world. One of the main reasons of disability and mortality in COPD is decompensate of chronic cor pulmonale. We are studied the endothelium dependent vasodilatation, level of ET 1 in plasma, central and pulmonary circulation ultrasound parameters at 60 patients with 2 and 3 stages COPD. The endothelium dysfunction was found in 65% of patients. The reduction of endothelium dependent dilation of brachial artery, diastolic disorders and level of pulmonary artery systolic pressure at COPD patients are the early prognostic factors of progress cor pulmonale and pulmonary bed disorders in future.