Brain natriuretic peptide and troponin I in patients undergoing plastic aneurysm of left ventricle
The goal was to assess dynamics of brain natriuretic peptide plasma (BNP) level after surgical correction of left ventricular aneurysm (LVA) in the early postoperative period and in the second half after surgery. 18 male patients were examined, most patients had III-IV functional class of heart failure (HF), most patients had manifestations of high functional class angina. All patients were examined by a standard protocol before the operation, including the determination of BNP and troponin I. All patients underwent myocardial revascularization and intraventricular LVA plastic. At the initial phase BNP was greater than normal levels in all patients. On the first day after surgery significant increase in the concentration of BNP in all patients was indicated. On the 7th day after the operation this indicator was determined by a downward trend. In the second half after the operation the level of BNP significantly decreased but was higher than normal levels in most patients. The level of BNP in patients undergoing plastic LVA was correlated with heart failure functional class and left ventricular ejection fraction. To assess the impact on the level of BNP prognosis in these patients the later observation is necessary. It is necessary to develop cardiospecific troponin specific performance standards for patients operated on for LVA in comparison with the other groups of patients operated on the heart to detect intraoperative myocardial damage.