Current views of etiopatogenesis of atopic dermatitis
The article represents the current data about the main components of pathogenesis of atopic dermatitis. The modern views to classification of atopic dermatitis are analyzed on the ground of results of basic pathogenetic mechanisms research. The authors make an assumption about the heterogeneity of atopic dermatitis, which involves various dermatoses with similar clinical presentation but different etiopathogenetic factors. The importance of food allergy by atopic dermatitis is proved. The data about the correlation between gastrointestinal tract dysfunction and disbacteriosis by atopic dermatitis are systematized. The evidences are represented which point out the necessity to consider intestinal disbacteriosis from the point of intestinal microbiota-tissue complexes. The up-to-date methods of intestinal microflora research are examined. It's also confirmed the importance of study of intestinal microbiota-tissue complexes by patients with atopic dermatitis to reveal new components of pathogenesis of this chronic dermatosis and to develop the new pathogenetic therapy.