MORPHOGENESIS OF OSTEOCHONDROSIS AND CORRECTION OF THE PATHOLOGICAL PROCESS BY TISSUE ENGINEERING IN THE EXPERIMENT
In the first section of the work the main provisions of the pathogenesis of intervertebral osteochondrosis, which is based on a violation of the microcirculation of metabolites and lymphatic drainage are formulated. The second section covers the experimental study on restoration of anatomic and metabolic ratios of the structural components by replacing the nucleus pulposus of the intervertebral disc chondral transplants. The possibility of correction of anatomical and morphological changes in the spine segment by tissue engineering is shown. The experimental study is the basis for the development of methods of correction of osteochondrosis in clinical practice.