Hypoxemic training: attention to negative sides for mitochondrions
The impact of hypoxia on the athletic performance remains a subject of debates. The complex character of adaptation to hypoxia that includes the high input of the individual factors suggests the absence of simple answers. Due to the high importance of the mitochondria for cell energy production, mitophagy should be taken in account as a negative effect of training under hypoxia and conditions associated with hypoxia (e.g. acidosis). This review summarizes and discusses the hypoxia impact on processes related to mitochondria functions. Some approaches are proposed to decrease the negative effect of hypoxia on mitochondria during the training process.