EVALUATION OF MOR PHO-FUNCTIONAL STATEOF THE LIVER AND K IDNEYS FROM SOWS IN CASE OF CHRONIC ENDOMETR ITIS
The article presents data on the morphofunctional state of the liver and kidneys in sows with chronic endometritis. The studies were carried out in the conditions of pig breeding enterprise on cross-bred sows, large white and Landrace breeds on 1-8 farrowing, body weight being 180-240 kg during pregnancy (103-105 days of pregnancy), in the suckling period, before weaning the piglets.The material of the study presented blood samples obtained from 25 sows in the stage of sexual cycle excitation, as well as parenchymal organs from 4 forced sows killed with signs of chronic endometritis. In the blood was de- termined by the content, creatinine, aspartate aminotransferase (AST), alanine aminotransferase (Alt), alkaline phosphatase (ALP) and gamma-glutamyltransferase (GGT). Samples of the material were subjected to histological examination. The biochemical blood parameters of sows 10 days before farrowing and during oestrum were determined, so the indicators characterizing the functional activity of the liver in sows of the second and third groups in comparison with the animals of the first group during pregnancy were Alat activity indicators were high- er by 18.0-26.8 %, ASAT - by 19.5 % and 28.7 %, GGT - by 15.7-18.0 % and during heat - by 12.5 % and 27,6 %, 9.66-18/0 %, 19.9-53.2 %, a creatinine, characterizing the functional state of the excretory sys- tem, during pregnancy was 6.78-20.0 % higher and during oestrum - by 6.17 % and 21.2 % with higher values in animals of the third group. In sows of the third group, the highest values of activity of APH, exceeding its indicators of the first group of animals during pregnancy by 9.37 % and during oestrum-by 13.1 % with less pro- nounced difference in this indicator in animals of the second group was registered. Histological studies in the liver of the sows revealed destructive changes in its architectonics, microcirculation disorders and the presence of haemorrhages in the paracentral zone of its lobules with the release of lymphoid cells from the bloodstream. Struc- tural and functional changes affecting the parenchyma of the cortical zone, characterized by dystrophic and necrotic processes in the vascular glomeruli and tubules with the accumulation of proliferating cells, histiocytes and lymphocytic cells, haemorrhages in the cavity of the kidneys capsules were revealed.Morphological changes in the designated organs indicate the course of chronic inflammatory process in animals.