THE POSSIBILITY OF BACTERIOPHAGE APPLICATION FOR TREATMENT OF THE PNEUMONIA CAUSED PSEUDOMONAS AERUGINOSA IN EXPERIMENT
The changes of rat lungs, liver and spleen after bacteriophage application for treatment of the pneumonia caused Pseudomonas aeruginosa were studied by method of light microscopy. It was revealed that specific phagotherapy leads to disappearance of signs of respiratory insufficiency, the general intoxication, the pneumonia and sepsis phenomena, increase in survival rate of animals. However, in the lungs after treatment there were signs of formation of abscesses, in liver – dystrophic changes of hepatocytes, and in spleen – hypertrophy and hyperplasia of lymphoid nodules. These complications, which can as well as be pneumonia consequences and phage use.