Evolution of opinions concerning surgical treatment of severe acute pancreatitis
We have obtained and presented an experience in treatment of 1242 patients with severe acute pancreatitis; studied surgery treatment results of 224 patients with this disease; developed and introduced treatment protocol of rendering medical aid to the patients of such category in clinical practice. The protocol is underlined on stages of the disease and prevalence of its process. We have assessed an efficiency of the treatment protocol based on the comparative analysis of those patients who may be associated according to the major indexes of the groups for the observation periods before (1991−2000) and after (2001−2007) during which the developed protocol was applied. Development and introduction of such standardized approach to selection of treatment protocol in case of severe acute pancreatitis let us reduce rate of the suppurative complications from 47,0 to 32,5%, the postoperative lethality from 39,6 to 23,1% and the general lethality from 33,3 to 15% (p<0,001) accordingly. Subject to the hydropic form of the severe acute pancreatitis, the general lethality has decreased from 8,8 in the group of comparison to 3,4% in the main group (p<0,05).