Diagnostic technique for initial open-angle glaucoma using Heidelberg contour perimetry and retinal tomography
The aim of the study. Develop a method for identifying the initial stage of open-angle glaucoma using Heidelber contour perimeter and retinal tomograph. Materials and methods. 624 patients (624 eyes), of which 236 were men and 388 were women, the average age was 63.4 ± 9.3 years. These patients were given a standard ophthalmic examination, Heidelberg contour perimeter (HEP), then Heidelberg retinotomography (HRT), depending on the obtained HEP results. Results. Correlation analysis of HRT scores revealed both direct relationships and inverse relationships of disease with certain HRT scores. We determined quantitative characteristics of optic nerve disc parameters, where revealed pathological changes. Each deviation in the individual parameters of the optic nerve disc related to risk factors. We carried out a comprehensive assessment of 7 main parameters, which received the best assessment of diagnostic informativity based on the results of the mathematical method of constructing operational curves (ROC analysis). The more deviations in the studied measures, the more risk factors, that is, the greater likelihood of the disease. The following is a comparison of the number of risk factors with the real value of the sick/healthy characteristic. Conclusion. We developed a technique to identify the initial open-angle glaucoma. According to the methodology, we carried out diagnosis in the presence of deviations in the individual values of the optic nerve disc parameters, which relate to risk factors. The most applicable in diagnostic practice is the presence of five risk factors, where specificity is 95 %.