FERRITIN''S ROLE IN BIOLOGICAL CIRCLES OF THE PERSON
A large number of works in the world literature including in Russia is annually devoted to a ferritin (F). Modern data on its structure and properties at physiological and pathological conditions of the person are provided. It is shown that F a certain physiological role in a human body is inherent (depot of iron (Fe), its transport, etc.) and it is surveyed as a nonspecific marker of an acute phase of inflammation ("an ostrofazovy protein or protein"). It is shown that the molecule F consists of 2 parts: apoferritin and colloid Fe hydroxide. F takes special part in exchange of Fe (its stocks). F it was for the first time allocated from a horse lien and later it was found also in plants and microorganisms. Formed in various organs and tissues F in the minimum quantities it is allocated in blood serum. At healthy adults blood serum level F generally depends on a floor and is insignificant from age. In recent years other physiological properties F which aren't bound immediately to exchange of Fe are found. It turned out that N-izoformy F can suppress a proliferation of blood cells. The N-ferritin is capable to slow down a proliferation of myeloid and lymphoid cells, prikchy activation of its education can be bound to attempt of an organism to suppress their oncologic body height. The quantity F in blood serum also increases at some acute and chronic diseases of a liver, a myocardial infarction, at starvation and attrition and many inflammatory processes. In these cases F in blood serum death of cells and allocation of intracellular fraction is the main reason for augmentation. The data which are available in literature confirm data about F biological mediums of the person, as about a marker protein of ostrofazovy reaction or inflammation and a destruction.