Radionuclide diagnosis of diabetic nephropathy
The authors report the results of investigation of the state of filtration-excretory function of the kidneys, renal hemodynamics in patients with type 1 diabetes mellitus and stage II and III diabetic nephropathy. The changes in filtration-excretory function and renal hemodynamics manifested by various changes of minute volume of glomerular filtration, maximal accumulation time and half-excretion of the radiophamaceutical as well as reduction of arterial in-flow and venous out-flow in patients with pre-clinical stages of diabetic nephropathy. The changes in the parameters of dynamic kidney scan and intrarenal hemodynamics were observed in patients with diabetes mellitus with stage II diabetic nephropathy and absence of albuminuria.