On the problem of the pathogenesis of pelvic dysfunction
The authors present an analysis of literature data concerning the pathogenesis of pelvic dysfunction. A search and analysis of world and Russian publications over the past 7 years included in PUBMED, MEDLINE, eLIBRARY.RU databases was performed. The review deals with the influence of spontaneous labour, physical load, genetic predisposition on the development of genital prolapse. Special attention is paid to the connective tissue and neuromuscular components of the pelvic floor in the norm, during pregnancy and in the presence of symptoms of its dysfunction. The pathogenesis of pelvic floor dysfunction is a multi-factor process, when in case of genetic predisposition and under the impact of predisposing factors pelvic organ prolapse finally develops. A high incidence of relapses of genital prolapse necessitates improvement of the existing methods of treatment and elaboration of new methods based on detailed study of the pathogenesis of this disease.