METHODS FOR DETERMINING THE GENETIC IDENTITY OF BIOLOGICAL OBJECTS
The aim of the study was to study some features and carrying of a comparative analysis of various methods used to characterize the degree of foreignness - the identity of biological objects. The feasibility of using leukocytes as test cells to detect histocompatibility antigens in laboratory and clinical practice is discussed. It is shown that to characterize the degree of foreignness - identity, you can use serological, molecular, genetic and cellular methods. Since biochemical markers are group-specific, the identification of biological objects by existing methods of classical biochemical and immunological analysis, if possible, then using many different systems, each of which, taken in isolation, has only relative value. It is noted that molecular genetic identification analysis allows one to identify individual genetic differences or genetic similarities of biological objects and to establish their difference, identity or their genetic relationship. In characterizing a method for determining the genetic identity of individuals based on contact lymphocyte-granulocyte interaction, the possible role of T-lymphocytes, in particular γδ T-lymphocytes, is examined.