THE EFFECT OF THE MIXING RATE OF THE REACTION MIXTURE ON THE DISPERSED CHARACTERISTICS OF THE NANOEMULSION OF FAT-SOLUBLE VITAMIN E (ALPHA-TOCOPHEROL ACETATE)
The article presents the results of a study of the effect of the mixing rate on the dispersed characteristics of nanoemulsions of the fat-soluble vitamin E (alpha-tocopherol acetate). The mixing speed was varied in the range of 3000-22500 rpm. The average hydrodynamic radius of the micelles of fat-soluble vitamin E was considered as an output parameter, which was determined by the method of the dynamic light scattering. It was found that as a result of synthesis, micelles of the fat-soluble vitamin E emulsions are formed, having a monomodal size distribution. The smallest average hydrodynamic radius of the particles was 22 nm. It was found that an increase in the mixing speed from 3000 to 22500 rpm causes a decrease in the average hydrodynamic radius of micelles. The greatest changes are observed at τ = 30 s: a decrease in the average hydrodynamic radius of micelles R<sub>m</sub> occurs by 3,3 times (from 210 to 63 nm). It is important to note that an increase in other synthesis parameters also leads to a decrease in the value of the average hydrodynamic radius of micelles of the vitamin E nanoemulsions. By v = 22500 rpm an increase in the mixing time τ from 30 s to 270 s leads to a decrease in R<sub>m</sub> by 19 nm (from 63 to 44 nm).