Biological processes in human body. Aging and tumorigenesis. Role of telomerase
Telomeres are the structures disposed on the end of the chromosomes that protect cells from damage duringcell replication. They are also called «mitotic clock» - with each division cycle telomere length decreases gradually, they lose their ability to perform a safety function program is initiated apoptosis and cellular senescence. The significant role of a reduction in telomere length was described in patients with hematologic malignancies. Further study of telomerase activity is a promising direction for the development of new drugs in oncology, hematology and gerontology.