Effect of acute kidney injury on prognosis in patients with acute decompensationof chronic heart failure
<i>Background</i>. Rate and severity of acute kidney injury (AKI) in patients with acute decompensated HF (ADHF) are understudied. <i>Aim</i>. To evaluate rate and severity of AKI in patients with ADHF and to specify the relationship of AKI with mortality. <i>Materials and methods</i>. The study included 104 patients with ADHF, 58 (56 %) males and 46 (44 %) females, mean age 65.3±10.7 years. In most of the patients (82, 79 %), HF was induced by IHD. ADHF was diagnosed according to Russian Society of Cardiology Guidelines. AKI was diagnosed and classified according to KDIGO Guidelines (2012). <i>Results</i>. AKI was diagnosed by creatinine level in 76 (73 %) patients. Stage 1 AKI was diagnosed in 61 (59 %) patients; stage 2 - in 13 (12 %) patients, stage 3 - in 2 (2 %) patients. Five (5 %) patients died during the hospitalization period. All dead patients had AKI. The probability of hospital mortality was higher for patients with stage 2-3 AKI than for other patients (OR, 11.2; 95 % CI 1.6-76.3). <i>Conclusion</i>. More than a half of ADHF patients have AKI. Most of the patients (59 %) have stage 1 AKI. Hospital mortality is higher for patients with stage 2-3 AKI than for patients without AKI.