USE OF ALLOKIN-ALPHA TO STIMULATE LEUCOPOIESIS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS B AND C
Objective: to determine the efficacy of allokin-alpha for the stimulation of leucopoiesis in the treatment of chronic hepatitis B (CHB) and C (CHC). Subjects and methods. Seventy-six CHB and CHC patients with leucopenia were treated. Half of the patients received therapy incorporating allokin-alpha; the other half had traditional therapy. Results. In the patients with chronic viral hepatitides on combination therapy including allokin-alpha, leucopenia and neutropenia were shown to significantly diminish and to elevate the levels of white blood cells and segmented neutrophils (p < 0.05). Conclusion. Allokin-alpha is able to stimulate leucopoiesis in patients with CHB and CHC, which allows leucopenia to be corrected.