CLINICAL EFFICACY OF GLUTAMATERGIC THERAPY IN PATIENTS WITH POSTSTROKE VASCULAR DEMENTIA
With the purpose to study effi cacy and safety of prolonged Glutamatergic therapy with akatinol memantine in vascular poststroke dementia, 42 patients, aged 59-79 years have been studied. A potential of 3-year course of akatinol memantine therapy has been studied in the open study. Effi cacy and safety of akatinol memantine were assessed clinically and with a battery of widespread scales and neuropsychological tests. Th e improvements of cognitive, functional and motor activities in patients with mild and moderate dementia indicate the high eff ectiveness of akatinol memantine. A prolonged Glutamatergic therapy allows to prevent the progression of cognitive impairment and development of vascular dementia.