ASSESSMENT OF TREATMENT EFFECTS BY LIMPHOTROPIC AND OZONE TECHNIQUES THE COMPLEX THERAPY OF OPIOID WITDRAWAL
The potential of the application of lymphotropic and combined lymphotropic and ozone medical technologies for correction of pain syndrome and kinetics of nonspecific response reactions of the organism, in the complex therapy of opioid withdrawal was studied. We investigated 146 patients distributed in three homogeneous groups. The control group received a standard therapy, the first main group - a complex of standard and lymphotropic therapy (LT), the second main one additionally to the mentioned complex received a course of ozone therapy (OT). It was shown that the therapeutic effectiveness of LT was determined by reducing influence on the pathological algic and stress systems decreasing their power and stability to the system effects of standard therapy. A correction of pain syndrome and acute stress lead to the activation of rehabilitation process on tissue (organ) level that followed by suppression of activity of immune/inflammatory response. The therapeutic effect of a combined application of LT and OT resulted in a reduction of a degree and fast liquidation of tissue damage, that had a normalizing effect on the kinetics of inflammatory/immune responses. The complex application of LT and OT techniques and standard therapy mutually potentiated the correcting effects with regard to the leading clinical syndromes, that ensured a smooth course of an opioid withdrawal, reduction of its duration and increase of the patients' rehabilitation potential.