Change of subpopulational composition of immunecompetent cells after splenectomy
The study is carried out using animals after splenectomy, general amount and subpopulational composition of immune competent cells to differentiation antigens (CD3+ - mature Т-lymphocytes, CD4+ - Т-helpers, CD8+ - an cytotoxic suppressor cells) in peripheral blood in early postoperative period. The parameters were controlled during 2nd, 5th and 7th days. It has been established that splenectomy of animal brings to expressed change the selected factors to 7th day with reduction of mature Т-lymphocytes and Т-helpers, increase cytotoxic suppressor cells.