Connection between clinical and biochemical efficiency of antiaggregationly therapy.
The purpose of research # to offer criteries of efficiency antiaggregationly to therapy and to prove presence correlations between biochemical and clinical resistance to preparations Acetylsalicylic Acid (АSA). Observed 58 patients with a stable stenocardia of pressure II#III FC. Estimated the ADF#induced aggrega# tion тромбоцитов and tolerance of patients to physical activity on a background of reception Trombo АSS 50 and АSA 125 mg/day. Criteria of efficiency are offered to antiaggregationly therapy (ААТ) by means of factor of sensitivity to desaggregationly to therapy (Ra %) and an exponent of the maximal aggregation (Amax). By means of these criteria insufficient sensitivity 34,5 % and resistance 27,6 % of patients on a background of reception Trombo АSS 50, and also insufficient sensitivity 17,2 % and resistance 20,7 % of patients on a background of reception АSA of 125 mg/day are revealed. Communication between efficiency ААТ and tolerance of patients to physical activity is revealed. Thus, the received results specify presence correlations between biochemical and clinical resistance to preparations АSA.