Metabolic Changes in Patients with Gout
The study was aimed to investigate metabolic changes in 154 patients with gout (mean age 57.7 years). The patients were divided into 2 groups: without tophi (n = 69) and with tophi (n = 85). The following parameters were assessed: blood pressure, body mass index, blood lipids, uric acid, blood sugar, blood coagulation parameters, and nitric oxide. Two thirds of patients had arterial hypertension, 89.6% of patients were overweight, and 83% of patients had atherogenic dyslipidemia. Hyperuricemia was registered in 92% of patients, hyperglycemia and decreased nitric oxide levels - in 52% of patients. Therefore patients with gout had serious metabolic changes that were important for the treatment of the disease.