Differentiation of sex: norma and pathology
The lecture deals with the differentiation of human sex. Details are presented: genotypical sex determination and differentiation in the development process in health and disease. Attention is paid to the features of meiotic genes and Y-chromosome, as well as to the inactivation of the X chromosome. Variants of hermaphroditism are presented. The author considers a number of pathological conditions, associated with sex differentiation, including Fragile X-chromosome, Turner’s syndrome, and others.