EFFICACY OF GENERIC ALENDRONATE ACID IN PATIENTS WITH OSTEOPOROSIS
The purpose of this study was to evaluate the long-term effectiveness of generic alendronate acid preparations in patients with osteoporosis according to data on densitometric research. 62 female patients aged from 50 to 79 were treated for at least 12 months. By means of roentgen densitometry it was revealed that the intake of generic alendronate acid is an effective method to increase bone mineral density (BMD) in the lumbar spine (4.53 %), proximal femur (2.83 %) and femoral neck (2.58 %). The patients` age does not have a significant effect on the rate of the BMD increase in the lumbar spine (F = 0.796; p = 0.456), but the BMD positive dynamics is estimated by the basal level of the vertebral bone mineral density (F = 7.512; p = 0.008). Before the study 32.3 % (n = 20) the patients had low-energy fractures but it did not influence the efficacy of the antiosteoporotic effect of alendronate acid preparations.