ROLE OF THE T-LYMPHOCYTE MEMBRANE PROTEIN CTLA-4 IN REGULATING IMMUNITY AND IMMUNOTHERAPY OF TUMOR
The review summarizes literature data about role of the T-lymphocyte membrane protein CTLA-4 in regulating the immunity. The mechanisms of using CTLA-4 by tumor cells to escape the immune response are shown. Special attention is paid to the issues of tumor immunotherapy based on blocking of immune check points.