Stratification of the risk of atherosclerosis of coronary arteries in patients with psoriasis
Importance. There are scientific data and clinical studies that show the high comorbidity of psoriasis and atherosclerosis of the coronary arteries in recent years. This fact indicates the presence of pathogenetic link between them, which has a multifactorial nature. However, there are no scales for assessment of the risk of coronary heart disease in patients with psoriasis.Purpose of the study. To give the objective criteria for assessment of the risk of coronary atherosclerosis in patients with psoriasis.Materials and methods. There were examined 90 patients with psoriasis and coronary heart disease with the help of clinical-anamnestic and laboratory methods. All patients were divided into two groups: the 1st one with psoriasis, the 2nd one with psoriasis associated with coronary heart disease. The ROC-analysis was done to determine the threshold values of laboratory parameters. There was done also a discriminant (multifactorial) analysis of clinical and laboratory categorical predictors of the risk of atherosclerosis of the coronary arteries in patients with psoriasis.Result. We obtained a statistically reliable model, which was developed on the base of individual assessment of the scale of the risk of atherosclerosis of the coronary arteries, which is clinically manifested through coronary heart disease in patients with psoriasis.