Sinthesis of monohalophthalic acid by oxidation of the corresponding substituted o-xylenes
A method for the preparation of monohalo-substituted phthalic acids by oxidation of the corresponding o-xylenes with dilute nitric acid at elevated pressure has been developed. The influence of the ratio of reagents on the yield of the target product and the composition of the resulting by-products has been studied. A method for isolating the target product by extraction with ethyl acetate, which made it possible to increase the yield of products, has been developed.