THE COMPARATIVE CHARACTERISTICS OF ANTIBACTERIAL PROPERTIES OF THE PEPTIDES OF THE ACTIVE SITE OF GM-CSF, AND SUBSTANCES DELIVERED FROM SUPERNATANTS OF HEMATOPOIETIC PROGENITOR CD34 <sup>+</sup>45 <sup>-</sup> CELLS
The antibacterial activity of synthetic peptides of the active site of GM-CSF and supernatants of CD34 <sup>+</sup>45 <sup>-</sup> hematopoietic progenitor cells has been investigated. GM-CSF peptides and cell supernatants were found to possess pronounced antibacterial activity, at that a combination of these substances has a more pronounced activity in comparison with the single substances. Possible mechanisms of the identified effects of synthetic peptides and substances from the supernatants of CD34 <sup>+</sup>45 <sup>-</sup> cells are discussed