STUDY OF AMINO ACID AND FATTY ACID COMPOSITION OF MEDICINAL PLANT RAW MATERIALS LEONTICE EVERSMAN-NI BGE
Currently, there is an increase in the market of herbal medicines in the territory of the Republic of Kazakhstan. This is justified by relatively low toxicity, a wide range of biological effects and the use of herbal remedies. Leontice ewersmanni B. belongs to the Berberidaceae family, has 5 species worldwide and 1 species in the Republic of Kazakhstan, is found in Central Asia, China and Georgia. As the main groups of biologically active substances, species of this genus contain flavonoids, tannins, hydroxycinnamic acids, polysaccharides, saponins and other compounds. The rational use of medicinal plant materials is one of the most important tasks of the pharmaceutical industry. One of the most important compounds in the complex of biologically active substances of medicinal plant materials are amino acids and fatty acids. The presence of 14 amino acids in the vegetable raw materials of Leontice ewersmanni B., of which the essential amino acids are: lysine, phenylalanine, histidine, leucine, isoleucine, methionine, valine, threonine. Fatty acid analysis showed 8 fatty acids: myristin, pentadecane, palmitin, palmitoline, stearin, olein, linol, linolene. The discovered amino acids can be divided into three functional groups - aliphatic, aromatic and heterocyclic. Aliphatic acids are represented by five monoaminomonocarboxylic acids (leucine, isoleucine, valine, alanine, glycine), two oxymonoaminocarboxylic acids (threonine, serine), two diaminomonocarboxylic acids (arginine, lysine), and one sulfur-containing acid (methionine). Of the aromatic amino acids, tyrosine and phenylalanine have been identified. Heterocyclic acids are represented by histidine, proline The results obtained indicate the prospects for further studies of the amino acid composition of Leontice ewersmanni B. and can characterize this species as a source of medicinally valuable substances with a wide range of pharmacological activity.