Clinical and hematological features of acute leukemia in Tajikistan
Some clinical features of acute leukemia in Tajikistan were observed. The analysis of the frequency of clinical symptoms and changes in the peripheral blood and myelogram in 961 patients with acute leukemia identified in the period 2000-2009 was conducted. All patients were divided into 4 groups: I group - 425 patients with acute lymphoblastic leukemia (ALL), II group - 326 patients with acute leukemia (AL), III group - 197 patients with acute myeloid leukemia (AML), IV group - 13 patients with undifferen-tiated type of leukemia. The main clinical syndromes of acute leukemia revealed: anemia syndrome - 64,2%, hemorrhagic syndrome - 43,0%, hyperplastic syndrome (lymphadenopathy - 48,9% hepatomegaly and splenomegaly - 16,5%) and pain (ossalgiya - 67,2%, sternalgiya-46,3%). Most suffer from acute leukemia in the age range from 20 to 29 years, which amounted to 17,5%.