The mechanism of action of the drug Cardos on heart failure model in rats
<i>Determined was the mechanism of action of the drug Cardos (antibodies to the C-terminal fragment of AT</i><sub><i>1</i></sub><i> receptor of angiotensin II) in experimental heart failure in rats and determined was its effect on the ratio of AT</i><sub><i>1</i></sub><i> and AT</i><sub><i>2</i></sub><i>-angiotensin II receptor subtypes and NO-synthase activity in cardiomyocytes. It is suggested that Cardos possesses modulating action on nitric oxide II metabolism in the myocardium.</i>