To the treatment of peritonitis caused by the pathology of the upper parts of the urinary system<i>.</i>
Based on the analysis of the materials of the case histories and clinical observations of 385 patients with peritonitis caused by injuries and injuries of the upper urinary tract, it was established that the use of lymphotropic antibiotic therapy and abdominal treatment with nitrogen monoxide (NO) significantly improved the results of treatment of this pathology. There is a decrease in the length of stay of the patient on the bed, a decrease in the number of relaparotomies and mortality. Determination of the concentration of amikacin during its lymphotropic administration against the background of therapy with nitrogen monoxide showed significant advantages over intravenous administration. The study of cellular and humoral immunity revealed rapid normalization of indicators already by the 7th day. At the same time, an increase in production of nitrogen monoxide in peripheral blood monocytes was observed 3 times, and in macrophages of peritoneal fluid - 4-fold. Clinical and economic analysis revealed that the use of NO- and lymphotropic therapy is 1.3 times more effective and more economical than using a «classical» treatment regimen.