ANTIATHEROSCLEROTIC AND HYPOLIPIDEMIC EFFECTS OF TREKREVIT
The problem of cardiovascular diseases is the leading one among the problems of the World Health Organization, thus justifying any attempts to identify both etiological and pathogenetic factors of their formation. At the same time, a special place is occupied by studies of the possibilities of pharmacological correction of the most frequent vascular pathology - atherosclerosis and pathology of the blood composition - hyperlipidemia. From the point of view of the concept of adaptation syndrome, the authors considered these phenomena as maladjustment. In this regard, the purpose of this study was to study the possibility of using a biologically active supplement trerevit against the background of basic treatment ofpatients with atherosclerosis and impaired blood lipid profile. To achieve this goal, the following methods were used. We examined 32 male patients aged 35 to 50 years with signs of carotid artery sclerosis. All patients received basic therapy with miscleron and aspirin. Patients of the main group, in addition to basic therapy, received trerevit at a dose of 4 tablets / day for 3 months. When using trekrevit in combination with basic drugs, lipid metabolism and indicators of the development ofsclerosis of the carotid arteries in patients significantly improved. The results obtained indicate the fact that in patients with atherosclerosis, basic therapy in combination with trerevitis has a high efficiency - almost 85%. In addition, this combination of drugs has organoprotective properties: during treatment, the thickness of the intima- media complex of the carotid arteries decreases, while in some patients it reached normal values. It is concluded that taking trerevit in addition to basic therapy reliably reduces metabolic disturbances in the patient, and also reduces changes in the vascular wall of the carotid arteries. In addition, trekrevit has a previously unknown property - to exert a potentiating effect on the effects of the basic drug miscleron. Finally, trerevit can be included in comprehensive programs as a complementary, compatible with other drugs, to improve the effectiveness of treatment and improve the quality of life ofpatients.