Functional state of mononuclear phagocyte system in patients with brucellosis
The article investigates the functional state of mononuclear-phagocytic system in 131 patients with different clinical forms of brucellosis admitted to the department of brucellosis of the Republican Center for Infectious Diseases (Makhachkala). The research of mononuclear phagocytic system was carried out by using NBT test and defines the number of functionally active cells (NFAC), the coefficient of the functional activity of monocytes (CFA), the number of phagocytic monocytes (CPM) and the activity coefficient of phagocytosis by monocytes (CAPM). Provence-degenerate studies have shown that among patients with acute and chronic brucellosis under subcompensation the functional status of mononuclear phagocytes impairs, and it increases NFAC and decreases CFA, CFM and CAFM. At the same time among patients with acute brucellosis immune dysfunction was more apparent than among patients with chronic brucellosis under subcompensation.