IMMUNOLOGICAL TESTS IN THE DIAGNOSIS OF TB INFECTION IN PEOPLE LIVING WITH HIV
In this research it was investigated a possibility of using immunological tests in the diagnosis of TB infection in people living with HIV. It was analyzed the results of medical examination of 345 patients with HIV-infection. In addition to standard clinical and laboratory examination there were made an immunological tests T-SPOT®.TB and skin test with recombinant tuberculosis antigen. Using a lab test T-SPOT®.TB on patients with HIV infection with established subsequently diagnosed with TB results were positive at 115 (54%) patients (95%CI 47,0-60,6%), the application of skin test with recombinant tuberculosis antigen 51 (23,9%, 95% CI of 18.7-30.1 %). In the group of HIV-infected patients without active TB, positive results of a laboratory test was obtained in 13 (9,9%) patients (95%CI of 5.9 to 16.1%>), using skin tests with recombinant tuberculosis antigen at 14 (10,6%, 95% CI 6,4-17,0%); tests demonstrated good consistency (к = 0,6, p < 0,001), indicating their equal opportunities to identify tuberculosis infection in people with HIV.