NERVE GROWTH FACTOR - A DIAGNOSTIC MARKER OF THE DEGREE OF NEUROLOGICAL DEFICIENCY IN CHILDREN
This article deals with the definition of nerve growth factor and its role as a marker of the severity of the neurological deficit in children the first year of life. The clinical picture and laboratory and instrumental data newborn screening is not always reliably determine the outcome of the pathology of the central nervous system, which in turn leads to adverse consequences in the future due to the lack of timely and adequate therapy. The study shows the NGF level – as the primary diagnostic and prognostic marker – on the severity of neurological deficits in children in the first year of life. These results allow us to consider NGF as a marker for the selection of adequate pathogenetically substantiated drug therapy and assessment of its effectiveness, since different drugs to varying degrees, have led to a change in NGF marker.