HYPERTENSION INCIDENCE DURING 16-YEAR FOLLOW-UP IN 25-64 YEARS OLD WOMEN WITH VITAL EXHAUSTION IN RUSSIA/SIBERIA (The epidemiological study based on the WHO program "MONICA-psychosocial")
Objective. To determine the effect of vital exhaustion (VE) on the relative risk of hypertension in female population of 25-64 years old during 16 years in a metropolis of Western Siberia (Novosibirsk). Design and methods. Within the framework of the third screening of the WHO «MONICA-psychosocial» program random representative sample of women aged 25-64 (n = 870), who were residents of one district in Novosibirsk, were surveyed. VE was measured by means of «MOPSY» scale. From 1995 to 2010 the women were followed for 16 years for the hypertension incidence. Cox proportional regression model was used for the relative risk estimation. Results. During the first 5 years of follow-up the relative risk of developing hypertension was 2,38 times higher in women with VE (95 % confidence interval = 1,03-3,87; p < 0,05); during 10 years of follow up there was a 2,32-fold and 2,34-fold risk of hypertension (for age group 35-44 and 45-54 years, respectively; p ≤0,05 for all estimations). The rate of hypertension incidence was higher in married women with VE, having high school education in «manual work» category and in those with higher education in class «executive officer». Conclusion. VE significantly increases relative risk of hypertension incidence in population of women aged 25-64 years. Incidence of hypertension is influenced by occupation class, marital status, educational level.