TOXICITY OF MAGNESIUM OXIDE NANOPARTICLES IN ACUTE, SUBACCUTE, AND SUCHRONIC IN VIVO EXPERIMENTS
MgO nanoparticles are of wide scientific interest due to the relative ease of synthesis, chemical stability and unique properties. An objective assessment of potential risks to human health requires experimental data on the toxicity and features of the biological action of MgO nanoparticles. The article detailed the results of an acute and subchronic experiment on white non-linear rats. Subacute toxicity study of MgO nanoparticles with similar physicochemical properties available in scientific publications were also analyzed. It has been established that in experiments in vivo, MgO nanoparticles have the dose-dependent general toxic effect with predominant disorders of the antioxidant system and liver functions and have genotoxicity in the chromosome aberrations test.