GOLD APPLICATION IN MEDICINE: PAST, PRESENT AND FUTURE Part I. Historic aspects of medical application of gold and its compounds
Gold has been used in medicine throughout the history of human civilization: starting from protective gold amulets to contemporary gold nanoparticles. The article is the literature data review on gold use in medicine. It reflects basic historical landmarks. Throughout human history gold has been of high value in everyday life and had contaversian attitude in scientific circles since it being used in medicine, giving rise to a storm of controversies and arguments. Controled clinical trials had appeared in the 20th century, it allowed scientifically to ground, to confirm some advantages of its use and to refute the opposite ones.