DETECTION OF DROTAVERINE AND ITS METABOLITES IN BIOLOGICAL OBJECTS
The article describes the method of isolation of drotaverine and its metabolites from biological objects by solid-phase and liquid-liquid extraction methods. Retention indices of the identified compounds were determined, indicating the main directions of fragmentation of drotaverine molecules, its metabolites and their acethylderivates, trifluoroacethylderivates and methylderivates during the study by the chromatomass spectral method (electron ionization).