Model of Control of Diurnal Melatonin Secretion by the Solar Radiation
The mathematical model of the control process of diurnal melatonin secretion under the influence of solar radiation on retina photoreceptors is proposed. Invariant relations for calculating melatonin secretion rate and its concentration in blood plasma are obtained. Spectral, time and energy characteristics of solar radiation synchronizing diurnal melatonin secretion and circadian rhythms in human are defined. A possibility of using the relations obtained is shown for arbitrary combination of calendar dates, local time of any time zone and geographical coordinates of a calculated point on earth surface. The adequacy of model is confirmed by coincidence of the calculation data with the results of independent experimental studies on diurnal secretion of melatonin and circadian rhythm in human. The model proposed can be used during investigation of diurnal secretion of melatonin and circadian rhythm in human.