CARDIOTOXICITY OF ANTICANCER THERAPY: ELECTROCARDIOGRAPHIC PHENOMENOLOGY IN CHILDREN AND ADOLESCENTS AT THE STAGES OF REHABILITATION
The relevance of studying the manifestations of cardiotoxicity in children and adolescents after the end of therapy is due to the risk of developing life-threatening complications. The phenomenology of ECG examination considering as indicative marks of manifestations of cardiotoxicity. The aim of the study was a comparative analysis of the severity of heart damage in patients with different toxic load of antucancertherapy. Materials and methods. A group of 293 patients was divided into 3 components depending on the nosological affiliation (acute lymphoblastic leukemia, tumors of the posterior cranial fossa, and a group of immunodeficient states). Results. Disorders of repolarization and rhythm disturbances are more common in patients with ALL. The most successful were those with immuno-deficiency conditions who did not receive anticancertherapy. Conclusion. The frequency and duration of rehabilitation courses is determining by the severity of the revealed manifestations of carditoxicity.