ALKYLATION OF C-PHOSPHORYLATED ACETAMIDINES BASED ON THE MOBILITY OF METHYLENE HYDROGENS
Interaction of sodium derivatives of C-phosphorylated acetamidines with different alkyl halides such as methyl iodide, ethyl bromide, butyl iodide, ethyl monochloroacetate and benzoyl chloride has been studied. The reactions occur in moderate conditions with a formation of alkylated methylene group products. On the base of CH-acidic properties of Cphosphorylated acetamidines a suitable method of their synthesis has been worked up.