Features of central hemodynamics in premature newborns with syndrome of persistent pulmonary hypertension
Structural and functional features of the cardiovascular system of premature infants contribute to the development of persistent pulmonary hypertension (PPH). PPH is a factor of the formation of cardiac remodeling and determines the degree of adaptation of the heart to a changing workload. 64 premature newborns were examined, 29 of which showed signs of persistent pulmonary hypertension syndrome. Children underwent standard clinical examination, evaluation for somatic and cardiac status, instrumental study included an echocardiography with dopplerometry. We found out that PPH causes longer hemodynamic adaptation, accompanied by dilatation of heart chambers, thickening of the interventricular septum and posterior wall of the left ventricle, the functioning of fetal communications, increasing the basic speed indexes, reduced cardiac output. Remodeling of the heart chambers in preterm infants with signs of PPH by the end of the first month of life has a tendency to decrease.