Anti-Thrombotic Therapy as a Means for Improving Perinatal Outcome in Women with Placental Insufficiency (Literature Review)
Here we reviewed the studies aimed at using anti-thrombotic therapy in pregnant women with impaired placental function (placental insufficiency). The majority of the studies published over the last 20 years examined administration of low molecular weight heparins, acetylsalicylic acid and dipyridamole. Convincing data about benefits of applying the second-generation low molecular weight heparin such as bemiparin vs. aspirin during anti-phospholipid syndrome in pregnant women are provided. Use of bemiparin during pregnancy in women with thrombophilia was safe and efficient, and provided high rate of live births with lacking any maternal and fetal complications.