GOODPASTURE SYNDROME WITH ISOLATED KIDNEY DISEASE
Goodpasture syndrome is a rare variant of a systemic vasculitis, arising from the appearance of antibodies on the basement membrane of the glomerular capillaries (BMC) and/or alveoli, manifesting itself in pulmonary-renal syndrome. The article provides a review of the literature on this topic as well as own observation. The case demonstrates the features of Goodpasture syndrome progression in a young woman with isolated kidney damage, expressed by persistent hematuria, moderate nephrotic syndrome and a decrease in the kidney function. The presence of only renal lesions cast doubts on the initial Goodpasture syndrome diagnosis, but using serological test and morphological studies revealed antibodies on the basement membrane glomeruli and allowed for diagnosis verification. Immunosuppressive therapy glucocorticoids and cytostatics without plasmapheresis stopped inflammation along with a complete restoration of kidney function.