Obesity and the reproductive function: the current state of the problem
The past decades have seen a steady growth of various neuroendocrine disorders in overweight and obese women. Obesity has been recognized worldwide as one of the most important problems of modern healthcare due to its high prevalence and involvement in the development of numerous, among them lethal, diseases. At present, many scientific and practical issues remain unsolved, first of all, those related to somatogenic and neuroendocrine disorders in a woman's body. As a rule, disorders of the reproductive function and development of proliferative changes in the reproductive organs are combined with changes in the neuroendocrine regulation of carbohydrate and lipid metabolism. The article includes data from international and Russian publications on this problem over the last 10 years, found in the Pubmed publication resource. The current understanding of the prevalence and causes of developing obesity is discussed. The effects of the changes in the neuroendocrine regulation of carbohydrate and lipid metabolism on the female reproductive function and development of gynaecological diseases are described.