Biologically Active Piperidin-Containing Mannich Bases
A review of the results of scientific research in the field of synthesis and study of the biologically active properties of piperidine-containing Mannich bases carried out in recent years is presented. The presence of high biological activity in aminomethoxy derivatives containing a piperidine fragment was shown. Some Mannich piperidine bases are reported to have high antibacterial activity against <i>S.aureus, S.epidermidis, E.coli, K.pneumoniae, P.aeruginosa, S.typhi, Sh.flexneri</i> and <i>Pr.mirabilis</i>, as well as antifungal activity against <i>M.gypseum, M.canis, T.mentagrophytes, T.rubrum</i> and <i>C.albicans</i>.