ASSOCIATION POLYMORPHISM OF GENES OF GLUTATHIONE-DEPENDENT ENZYMES WITH REPRODUCTIVE PATHOLOGY IN WOMEN
This review covers analysis of modern ideas of ethiopathogenesis and mol ecul ar genetic bases of reproductive pathology in women. A multifactorial background for female infertility has been shown, with genetic as well as environmental factors influencing its development. Many studies have implicated oxidative stress in the pathogenesis of infertility causing diseases of the female reproductive tract. On the first line of defense against reactive oxygen species in cells of all organisms are low molecular weight compounds. Particular attention is attracted, by including tripeptide glutathione, which is contained in cells in milimolyarnyh concentrations. He participates in many enzymatic and non-enzymatic antioxidant protection, paths. International scientific articles about correlations between polymorphism of genes of glutathione-dependent enzymes with reproductive pathology. The conflicting results are received.