Clinical and morphological data correlations of cholesteatomas in children
Middle ear cholesteatoma (H71.0 in ICD-10) is a form of otitis media which represents a significant originality due to lack of common mechanisms of its development. Cholesteatoma is most often considered as a complication of chronic suppurative otitis media (CSOM). Unfortunately, there are not so much written in literature on the cholesteatoma against non-perforated forms of otitis media in children. In any case the development of cholesteatoma is accompanied with inflammatory process, characterized by progressive growth and destruction of epithelial and bone structures of middle ear. Changes in tissue in the middle ear with cholesteatoma are morphologically characterized by basic properties which inherent to epithelial tissue: proliferation, diff erentiation, migration, and metaplasia.