COMPREHENSIVE ASSESSMENT OF BIOMEDICAL RISK FACTORS FOR CONNECTIVE TISSUE DYSPLASIA DEVELOPMENT AMONG THE STUDENTS OF IVANOVO UNIVERSITIES
The article is concerned with topical biomedical issue - study of the concentration among the population genetically deterministic morphofunctional diseases of a connective tissue (connective tissue dysplasia - CTD) that leads to the chronic illnesses' formation, lowers living standards and affects the population health in general. Research methods - screening diagnostic with the use of adapted questionnaire, made on the ground of the national recommendations, coordinated international diagnostics criteria and data of the score table of T. I. Kadurina, L. N. Abakumova. Type of the research - cohort research held by means of survey of the students of Ivanovo universities. Results of the research. The score of the risk factors of CTD progression was held on the ground of screening diagnostic among the students. Morbidity of CTD on the ground of phenotypic character analysis among the population of Ivanovo region at the age of 21 ± 2 comprised 22,6 %. In this age group gender is not an essential risk factor for development of CTD. The most common reportable symptoms of CTD - Pathology of Skeletal System (47,0 %). Where the leading positions belong to scoliosis (59,0 %) and flatfoot (43,7 %). Body weight excess or deficiency can be a trigger of CTD. 23,0 % of students with frank CTD extent have chronic illnesses of digestive system that can both arise from CTD and increase CTD development. Conclusion. High frequency of CTD symptoms occurrencing indicates concentration of gene-mutation of biogenesis of a connective tissue among the students of Ivanovo universities. For this reason the problem of carrying out of measures of early CTD detection and its preventive measures becomes a topical issue.