Application of the rapid method of laser fluorescence spectroscopy to determine the sensitivity of pathogens to antibacterial drugs
The aim of the work is a comparative analysis of the effectiveness of the express method of laser-fluorescence spectroscopy to determine the sensitivity of bacteria to antibiotics. Materials and methods. The sensitivity of the purulent discharge microflora, obtained in diseases of the lacrimal tract (dacryocystitis, conjunctivitis) - 16 samples, from the sinuses (maxillary sinusitis) - 18 samples, using the method of laser-fluorescence spectroscopy, as well as traditional bacteriological study using anaerobic cultivation techniques for comparison, was studied. Results and conclusions. Significant differences in fluorescence power were found depending on the sensitivity/resistance of strains to antibiotics. The results obtained allow to recommend to ophthalmologists, dentists, otorhinolaryngologists the appointment of the drug, in the sample with which there is a maximum decrease in fluorescence, compared with the control. The proposed rapid test allows the practitioner to avoid the empirical choice of medical support,