CHEMICAL COMPOSITION OF THE ETHANOL EXTRACT OF COMMON TANSY (TANACETUM VULGRE L., ASTROVE FAMILY - ASTERACEAL)
The research purpose is to deepen our knowledge of the material composition of the organic matter of common tansy in addition to those already known in the literature on phytotherapy, as well as to determine new directions of the pharmacological action of drugs based on it, using the method of chromatography - mass spectrometry for a detailed study of the chemical composition of the ethanol extract of the common tansy. Materials and research methods. The flowers of common tansy were extracted with ethanol in a Sosklet apparatus. At the end of the exhaustive extraction, ethanol was distilled off on a RE - 52AA Rotary Evaporator. The residue was weighed and analyzed. Analysis conditions: gas chromatography - mass spectrometry was carried out using a GC - 2010 gas chromatograph connected to a GCMS - TQ - 8030 triple quadrupole mass spectrometer running the GCMS Solution 4.11 software. Results and its discussion. The report contains the results of a study of the chemical composition of common tansy using gas chromatography - mass spectrometry. This made it possible to identify 89 individual compounds for which the quantitative content was determined, mass spectra and structural formulas were obtained. The structure - group composition of the extract was calculated for each compound. The list of individual components has been significantly expanded and refined. Certain assumptions have been made regarding the physiological effect of an alcoholic preparation of common tansy, taking into account the peculiarities of its chemical composition.