CORONARY ARTERY DAMAGE ESTIMATION BY MEANS OF CORONARY ANGIOGRAPHYIN PATIENTS WITH STABLE ANGINA ASSOCIATED WITH CHRONIC GASTRITIS
The goal of the paper is to study the peculiarities of the coronary lesions by means of coronary angiography in patients with stable angina associated with chronic gastritis.Materials and Methods. The authors examined 95 patients with stable angina. All the patients were divided into three groups, depending on the type of chronic gastritis (CG). Group I (n=31) enrolled patients with stable angina and multifocal atrophic gastritis, group II (n=37) consisted of patients with stable angina and non-atrophic gastritis and / or gastroduodenitis. Group III (n=27) was the control one. The groups were similar in age and BMI. Coronary angiography was performed to verify the degree of coronary bed lesion. Fiberoptic gastroduodenoscopy and biopsy was carried out to verify the type of gastroduodenal lesion. Lipid profile, GFR, and uric acid level were also evaluated.Results. Patients with functional class III angina prevailed in the first group. Single-vessel coronary artery disease dominated in patients of the second group; the two-vessel coronary artery disease was mainly found in groups II and III, and the three-vessel coronary disease was peculiar to the patients of the first group. Stenosis of at least one affected artery (51 %-99 %) was widespread in group I. Laboratory tests showed that GFR in the study groups corresponded to CKD C2, target lipid level was not reached, and uric acid level was significantly higher in group I.Conclusion. Patients with stable angina associated with atrophic multifocal gastritis demonstrate more severe manifestations of ischemic heart disease. It is characterized by a higher functional class of angina, impaired renal functional status (decreased GFR and increased uric acid level). This group of patients is marked with a more apparent lesion of coronary arteries: a three-vessel lesion of the coronary bed and stenosis of at least one coronary artery (51 %-75 %, 76 %-95 % and 95 %-99 %).