THE ANALYSIS OF MECHANISMS OF THE NON-CLASSICAL PATHWAY OF HSP-70 SECRETION IN LYMPHOID CELL POPULATIONS
A number of recent studies have demonstrated the involvement of plasma membrane lipid rafts and endolysosomes in the mechanism of HSP-70 secretion by several cell types. The present work was carried out to study the possible involvement of these cell structures in exocytosis of HSP-70 in the populations of murine lymphoma EL-4 cells cultured in vitro. The data obtained indicate that the formation of the extracellular pool of HSP-70 in our model did not depend on the lipid rafts and endolysosomes.