Immune and Metabolic Associations in Diseases of Complex Genesis
Clinical models of ischemic and hemorrhagic strokes, aggravated by metabolic syndrome and diffuse liver diseases in the evaluation of immuno-biochemical parameters and the use of formalized statistics show: the formation of a qualitatively homogeneous type under the influence of the metabolic syndrome, a more pronounced hemorrhagic stroke products of free radical oxidation of lipids and proteins, predominant activation of enzymatic and non-enzyme-commutative mechanisms of antioxidant system on a background accumulation of inflammatory cytokines, and in patients with diffuse liver diseases – the presence of the universal connection mechanism of free radical oxidation intensity (FRO) with the development of cytolytic syndrome, disorders of lipid metabolism, immune status, initiation of apoptosis mechanisms.