HORMONE LEVELS IN BLOOD METABOLIC BALANCE PREGNANCY WITH FETAL MACROSOMIA
Fetal macrosomia is one of the priorities of modern obstetrics, defining a significant percentage of complications for both mother and fetus. The paper presents data on the levels of glucose, insulin, leptin, ghrelin, growth hormone in 58 women with full-termpregnancy, gave birth to the term child with a normal body weight (group 1) and 86 patients who gave birth to children with a mass of 4000 g and more (group 2). It was found that the level of blood glucose in clinical groups had no significant differences, the average concentration of insulin was statistically higher in the 2nd group. By the concentration of insulin in the blood of the mother and the weight of a newborn found an average positive correlation. The average concentration of leptin at the fetal macrosomia was significantly higher than in group 1. Average concentrations of ghrelin had no statistically significant differences between clinical groups. Revealed significantly higher levels of growth hormone when thefetal macrosomia. The results indicate that the formation of fetal macrosomia by high blood levels of leptin pregnant, growth hormone on the background of insulin resistance.