ASESMENT OF LIVER FIBROSIS EXTENT IN PATIENTS WITH CHRONIC HEPATITIS C, ROLE OF INDIRECT MARKERS OF LIVER FIBROSIS
The assessment of liver fibrosis extent is essential to determine the correct management of patients with chronic hepatitis C. For non-invasive diagnostics of fibrosis the indirect markers of liver fibrosis are used: platelet count, AST, ALT and their combinations. On the basis of 110 of patients investigation the early, advanced fibrosis and liver cirrhosis were defined with the use of indirect markers. The application of indirect markers of liver fibrosis allows avoiding of liver biopsy in 84,5% of patients with chronic hepatitis C.