COMPARATIVE CHARACTERISTICS OF EXPRESSION INSULIN RECEPTORS IN THE SUBCUTANEOUS FAT DEPOTSAND THE APPENDAGE IN PAT IENT S WITH OBESITY AND METABOLIC SYNDROME
The paper presents data on quantitative characteristics expression insulin receptors in different types of fat (subcutaneousand visceral adipose tissue) in patients with normal body weight and different degrees of obesity. Used modern immunohistochemicaland morphological methods. Proved that with increasing degree of obesity increases deficit of cells - producers of insulin receptors inall types of of adipose tissue. Dysfunction of insulin-producing activity progresses with increasing degree of obesity and prevails invisceral adipose tissue. Made conclusion about the presence of morphological preconditions for insulin resistance in obese patients,which dominates in the presence of visceral obesity.