Radionuclide Study as a Diagnostic Method in Patients with Lesions KNEE in Juvenile Chronic Arthritis
Radionuclide (scintigraphic) study was conducted in 126 patients aged from 2 years and 6 months up to 17 years with juvenile chronic arthritis (JCA). The aim of the study was to determine the activity of inflammation in joints and the diagnostic value of the radionuclide method in patients with the disease. We used two-phase scintigraphy: The first phase was assessment of intensity of the perfusion, the second phase was assessment of intensity of accumulation of radionuclide pharmacological drug in bone tissue. To determine an inflammation, the nature and level of perfusion in the knee joints were considered, and the qualitative and quantitative analysis of radionuclide changes was performed. Scintigraphic examination revealed that the intensity of accumulation of radionuclide pharmacological drug correlates with exudative and proliferative changes in the affected knee joints. Subclinical signs identified by scintigraphy of the knee allow early diagnosis of JCA.