TURMERIC IN THE TREATMENT OF UROGENITAL DISEASES
Turmeric is a well-known medicine of ancient and modern medicine. Turmeric rhizomes contain essential oil consisting of fellandrene, cingiberin, sesquiterpene ketones, borneol and other terpenoids, mono-terpenes of propanoic acid, sesquiterpenes of bisbolonium sexwiterpenes, 11 flavonoid glycosides, one dihydroflavonoid glycoside. The main biological active substances of turmeric rhizomes are turmoids - polyphenols. The main curcumoid is curcumin-diferuloylmethane, 1,7-Bis (4-hydroxy-3-methoxyphenyl) -1,6-heptadiene-3,5-dione. Thanks to the properties of curcumin to block inflammatory enzymes, it has a beneficial effect on chronic kidney disease. Randomized, placebo-controlled clinical trials have shown the efficacy of curcumin skin pruritus treatment in uremic patients. Taking curcumin improves glomerular filtration, has a renoprotective effect. Curcumin is also effective in the treatment of prostatitis. Experimental studies have shown that turmeric oil inhibits activation of the NF- λ B pathway by reducing the expression of phosphorylated p65, reduces inflammatory responses and cell survival in prostate tissues, leading to inhibition of the development of benign prostatic hyperplasia in rats. Taking turmeric has no side effects and reduces plasma levels of hs-CRP, IL-6, and TNF- α, accompanied by elevated albumin levels in hemodialysis patients and can be considered an effective anti-inflammatory supplement. Taking curcumin prevents damage to renal tissue when taking gentamicin, cisplatin, doxorubicin.