Immunotherapeutic approaches at treatment of children with different variants atopic dermatitis
Children in the age of from 4 till 15 years suffering atopic dermatitis (AD) are carried out clinical, allergic, endoscopy and immunological examination. As a result of clinical supervision 4 groups of children were generated: with pathology of gastro-intestinal tract (GIT), with a food allergy, with dysbiotic disorders and with allergy of food additives. Is investigated and is analyzed immunograms of children. In view of the analysis of the basic parameters immune status and clinical and laboratory features, the introduction immunomodulating therapy in algorithm of treatment and rehabilitation of children with AD. At AD with a pathology of the top department of a digestive path (1 group of children) the following circuit immunomodulating therapy was carried out: timalin, likopid, vitamin A and plasmol. To children 2 group with a clinical equivalent of the status dysbiotic disorders the following complex immunomodulating therapy: polyoxydoniy, rybomunil, scarlet. Children of group №3 have received following complex immunomodulating imunofan, likopid, US- influence, 0,25% a solution derynaty, metyluracyl. For children 4 groups the immunomodulating therapy included accoding to basic parameter of the changed system of immunity: t-activin, entegnin, roncoleukin, cygapan. The given research has shown efficiency immunomodulating therapy on laboratory indexes and achievement long clinical remission in groups of surveyed children.