Influence of chronic opisthorchiasis on sustained virologic response in patients with chronic hepatitis C during standard antiviral treatment
In order to assess the impact of chronic opisthorchiasis on virologic response in patients with chronic hepatitis C were examined 30 naive patients with chronic hepatitis C in combination with opisthorchiasis and 30 patients with chronic hepatitis C without opisthorchiasis. All patients received antiviral therapy with IFN-α or PegIFN-α and ribavirin during 24 weeks. Viral load was assessed on 4, 12, 24 weeks of treatment and at 24 weeks after treatment. In result, there is no negative influence of chronic opisthorchiasis on RVR and SVR in patients with chronic hepatitis C during 24 weeks of antiviral treatment.