HISTOCHEMICAL CHARACTERISTICS OF REPARATIVE DENTINOGENESIS OF THE TOOTH PULP WHEN USING TISSUE-ENGINEERED STRUCTURES
The role of C-kit-positive cells of the tooth pulp in optimization of reparative dentinogenesis in biological methods of treatment of pulpitis in exremental animals was studied. A model of acute pulpitis with subsequent amputation of the vital pulp was received in vivo on 80 incisors of the lower jaw of he-sheep. The use of tissue-engineered construction composed of collagen sponge, hydrogel PuraMatrix/3DM and ectomesenchymal cells as a biological methods of treatment has allowed to protect better the pulp against infection, to optimize the inflammatory process with the activation of proliferation and acceleration of formation of dentinal bridge.