IN THE WAKE OF GENETIC RESEARCHES OF IDIOPATHIC SCOLIOSIS
The idiopathic scoliosis is known since the time of Hippocrates and Galen, but still his etiological factor remains not established. Many theories proclaimed in last years were rejected. Now the predominating theory is genetic. If to trace a path of researches, then it is possible to reveal the significant amount of the genetic works of different level devoted to searching of genes/genes - a pathological factor of development of idiopathic scoliosis. In the submitted review the analysis of the most representative genetic researches, the bound to a regulation of body height, development, metabolism of structural components of connective tissue, connection with puberty and alarm paths (melatonin, serotonin) is undertaken. Also full-genomic and full-associative researches (GWAS) are considered. In each of analyzed researches locus which in other populations were not identified were received. What a conclusion follows from that the answer to the main issue in what the reason of development of idiopathic scoliosis, in these researches it is not revealed. On the basis of characteristic long-term researches authors state the interpretation of the nature of idiopathic scoliosis.