INFLUENCE OF EXTERNAL FACTORS ON INTEGRITY OF MITOCHONDRIAL DNA STRUCTURE
The influence of different methods of DNA isolation and storage conditions on the integrity of the primary structure of the molecule was studied. We showed that DNA isolatian with CTAB buffer can damage mtDNA, but no damage than with the isolation of DNA using sorption columns. It was also found that a significant number of damage accumulated after repeated freezing-thawing of the DNA sample.