Comparative effectiveness of trimetazidine and combining it with Omega-3 triglycerides and in post-infarction period (according to the ECG Holter monitoring)
136 patients with Q-myocardial infarction right after discharge from the hospital were randomized into three groups. Within six months in the control group consisted of 41 people, patients received the standard therapy (acetylsalicylic acid, perindopril, nebivolol, atorvastatin). Patients of the fi rst studied group (n=46) were additionally treated with trimetazidine 70 mg per day and patients of the second group (n=49) received trimetazidine with omega-3 triglycerides 1 g per day. Daily Holter electrocardiogram monitoring was done at the beginning of the study, and 6 months after the beginning of the study. The combination of trimetazidine and omega-3 triglycerides as a part of standard therapy appeared to be the most effective in preventive maintenance of painful and soft episodes of ischemia of a myocardium. The efficiency of trimetazidine as a part of standard therapy in the 1-st group was intermediate between the 2 and control group.