Interrelations between tuberculin adherent mononuclears and antituberculin antibody levels in course of pulmonary tuberculosis
In patients diagnosed with pulmonary tuberculosis for the first time that show positive clinico-radiological and laboratory dynamics after two months of intensive treatment, a moderate direct correlation was discovered between the number of tuberculin adherent monocytes, tuberculin adherent monocytes with higher expression of CD14 receptors, and anti-tuberculin antibodies. In patients with negative clinicical radiological and laboratory dynamics during treatment, a strong inverse correlation between the number of severe tuberculin adherent monocytes, tuberculin adherent monocytes with higher expression of CD14 receptors after 2 months of treatment, and antituberculin antibodies in one month. During complex treatment in combination with meglumine acridonacetate, the correlation between the number of tuberculin adherent monocytes, tuberculin adherent monocytes with higher expression of CD14 receptors, and antituberculin antibodies increases. A. strong correlation between the number of tuberculin adherent monocytes and tuberculin adherent monocytes with higher expression of CD14 receptors was discovered throughout the entire intensive treatment phase.