ASSESSING THE IMPACT OF OCTREOTIDE ON MORTALITY AND THE DEVELOPMENT OF SEPTIC COMPLICATIONS IN PATIENTS WITH INITIALLY SEVERE PANCREATIC NECROSIS
The purpose of the study - to evaluate the influence of octreotide on the dynamics of mortality and incidence of septic complications in patients with initially severe pancreatic necrosis (9 and more points on a scale APACHE-II). The results of treatment of 204 patients with a diagnosis of "acute destructive pancreatitis". Along with the one-dimensional statistical analysis used logistic regression and Cox regression, which allowed us to estimate the cumulative effect of octreotide and other potential predictors (factors severity of the condition and treatment factors) on mortality and incidence of septic complications in patients with necrotizing pancreatitis. Determined that the appointment of octreotide in the medical complex in patients with severe necrotizing pancreatitis, significantly affects the reduction of mortality and frequency of suppurative complications.