The analysis of morfophysiological changes of timus at chronic intoxication and administration of antioxidants
We have revealed regularities of morphological and functional changes in thymus tissues of rats at different stages of ontogenesis in norm, at chronic intoxication and on the background of application of a complex of antioxidants. We have compared the dynamics of the level of free radical processes in rat thymus tissue homogenates at different stages of ontogenesis at a chronic exposure to sulfur-containing natural gas and the action of a complex of antioxidants. Experiments have shown that the administration of a complex of antioxidants restores the weakened function, leads to lower levels of free-radical processes and apoptosis in all age groups, the effect being more pronounced in older animals.