RESULTS OF COMBINED COPPER NANOPARTICLES' AND LOW-INTENSITY LASER APPLICATION OF SIMULATED INFECTED BURN WOUNDS OF THE SKINS IN SURGICAL EXPERIMENT
Using the developed laser radiation method, skin burns of controlled damage depth and area were modelled. Peculiarities of the simulated wound process development in skin burn wound infection, markedness of antibacterial effect of various copper nanoparticles' concentrations and laser radiation parameters were detected. Combined local application of LILR and copper nanoparticles in experimental animals of the group under observation provided by the 7th day of treatment discontinuation of pathogenic microflora inoculation, by the 4th day – appearance of granulations, and by the 14th day of treatment-wound epithelization. The obtained findings of experimental studies with the use of planimetric and microbiological methods of investigation suggest rather high efficiency of combined application of copper nanoparticles and laser radiation, the effect surpassing that of standard methods of treatment in duration and adequacy of wound epithelization.