POSTSTRESSOR CHANGES IN FUNCTIONAL ACTIVITY OF CELLS OF PERITONEAL CAVITY OF MICE
The effect of acute and chronic cold stress in the conditions of the blockade of opiate receptors on the oxidative activity of mouse peritoneal macrophages was studied. It was established that acute cold stress (4°C, 4 hours), regardless of the blockade of opiate receptors, inhibits zymosan-induced oxidative activity of mouse peritoneal macrophages. Chronic cold stress (4°C, 4 hours, for 7 days) on the 7th day activates zymosan-induced oxidative activity of macrophages, blockade of opiate receptors leads to the cancellation of this stimulation. An increase in the concentration of corticosterone is observed both in acute and in chronic hypothermia and does not depend on the blockade of opiate receptors.