Fibrinolysis system disorders in patients with Diabetes Mellitus and Hypothyroidism
The article presents the results of study of blood fibrinolysis activity - Plasminogen activator inhibitor type 1 - PAI-1 in patients with diabetes mellitus type 1 and 2 and primary hypothyroidism. Disorders in the system of fibrinolysis by increasing the level of PAI-1 in patients with type 2 diabetes and the dependence of this parameter on the BMI, waist circumference, level of glycated hemoglobin, HOMA-IR, triglycerides, LDL cholesterol and microalbuminuria were identified. The positive effect of micronized fenofibrate on the lipid metabolism and PAI-1 in patients with diabetes mellitus type 2 in combination with primary hypothyroidism was founded.