Effectiveness of different methods of administration of antitubercular drugs in II B chemotherapy regimens at newly diagnosed patients with destructive pulmonary tuberculosis from the point of medical evidence
A controlled clinical study of the comparative effectiveness of different methods of introducing anti-tuberculosis drugs in the IIB chemotherapy regimens in 120 patients with newly diagnosed pulmonary tuberculosis was conducted. It is shown that the most optimal and efficient is the IIB chemotherapy regimen at parenteral administration of injectable anti-TB drugs, which allows for 3 month to halting of bacterial allocation in 92.5% of cases and the closing of caverns in the lungs of 80% of patients. In this clinically cured after 12 months of treatment was 97.5%. Medication complications as parenteral administration of drugs, and if with oral swallowed separate and combined drugs were detected in the same percentage of cases (17,5%, 20% and 12,5%), which completely stoped using pathogenic therapy.