STUDYING OF THE ISOMALTULOSE PREBIOTIC PROPERTIES IN VIVO CONDITIONS
Previously we developed a biotechnology isomaltulose is a natural sugar substitute with highly bacterial enzyme and proved its prebiotic properties in vitro conditions. The paper presents the results of studies of isomaltulose effects on the composition of normal flora in the intestine after oral administration to animals. The object of these studies used the albino mice. Assessment of intestinal microflora of animals was conducted under normal and pathological conditions – in experimental dysbiosis. The optimum dosage of isomaltulose is 0,3 mg per individual, which provides the maximum increase rate of weight gain of animal (1,6). It is shown that the introduction of sugar substitute reduces the number of bacteria pp. Streptococcus, Proteus, Ewingella are representatives of pathogenic microorganisms. In studies with experimental animals intestinal dysbiosis isomaltulose facilitated recovery of coliform bacteria and lacto bacteria.