The elastic properties of the vascular wall and inflammatory biochemical parameters in hypertensive patients with abdominal obesity
The study involved 125 patients (male and female) aged 47,67 ± 8,69 years. The patients were divided into 2 groups: group I - patients with hypertension n = 51 (AH ), group II - patients with hypertensive patients with abdominal obesity (AH with AO ) n=74. The structural parameters of the vascular wall were evaluated by sphygmography on the unit VASERA VS-1000 «FUCUDA»; evaluated biochemical parameters - total cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides, MDA (MD ) and inflammatory markers - homocysteine HS-CRP. Initially, in the second group of patients showed a significant breach of the elastic properties of the vascular wall (PWV-R / L, CAVI), exceeding the level of atherogenic lipid parameters (total cholesterol, low-density lipiproteiny ) and inflammatory markers ( high-sensitivity C-reactive protein, homocysteine ) compared to the first group. By logistic regression identified the biochemical predictors indicative of impaired elastic properties of the vascular wall.