Different methods of treatment on clinical manifestations and rates of mononuclear-phagocytic system in patients with brucellosis
Summaru. The functional status of mononuclear - phagocytic system in 131 patients with different clinical forms of brucellosis was studied. Special screening program includes the study of mononuclear phagocyte-systems using the NST test and a number of functionally active cells (NFAC), coefficient of the functional activity of monocytes (CFAM), the number of phagocytic monocytes (NPM) and the activity coefficient of phagocytosis by monocytes (ACPM). Studies have shown that patients with acute and chronic brucellosis against conventional therapy showed a statistically significant compared to baseline values decrease NFAC and increase CFAM, NPM and ACPM. Aminodihydrophthalasindione sodium inclusion in traditional therapy resulted in greater reduction NFAC and increase CfAM, NPM and ACPM. Aminodihydrophthalasindione sodium in complex therapy for patients with acute and chronic brucellosis proved high efficiency that manifested earlier disappearing of clinical brucellosis symptoms, restoration of disturbed functions of mononuclear-phagocyte system.