APPLICATION OF IMMUNOMODULATOR PIDOTIMOD IN A COMPLEX THERAPY OF CHRONIC PYELONEPHRITIS IN CHILDREN
Application of Pidotimoda in combination with a standard therapy for acute exacerbations of chronic pyelonephritis in children optimizes the immune status at the organ level (in the urine concentration IL-17 decreases by 3,0 times, the level of sIgA - increases by 16,9 times), reduces the activity of alkaline phosphatase blood leukocytes (by 4,6 times), effectively corrects manifestations of oxidative stress (decreasing free radical oxidation in serum - by 1,7-2,9 times, in urine - by 1,5 times), promotes more rapid extinction of main clinical syndromes.