ANALYSIS OF THE INTERNATIONAL PRINCIPLES OF DONORS’ BLOOD STORAGE: CRITERIA OF SUITABILITY AND PHYSIOLOGICAL CONSEQUENSES OF BLOOD TRANSFUSION
The analysis of the international principles of storage of donor blood is carried out. It is shown that in the world medical practice, most countries rely on standardized approaches to the issues of transfusion and storage of donated blood. In most states, the regulated time limits are reduced to a 35-40-day period of time. For the primary collection of donated blood, countries mainly use a single system of citrate anticoagulants, an acidic citrate-dextrose form for its apheresis. As a rule, the composition "saline solution-adenine-glucose-mannitol" is added to the red blood cell mass. Plasma components are stored in a frozen state, and platelet components are stored at room temperature with continuous stirring. In most countries, the process of leucoreduction before storage is common, with the prevailing type of leucodepletion filter depending on the country. Pathogen reduction technologies are being actively developed, but the purification of red blood cells is still under development.