BIOCHEMICAL INDICATORS OF LIPID AND CARBOHYDRATE METABOLISM IN PATIENTS WITH SCHIZOPHRENIA
In recent years, the metabolic problems in patients with schizophrenia have been actively discussed. There is evidence of the atherogenic nature of blood changes, as well as the violation of glucose tolerance in schizophrenia. Objective of this research is to study biochemical changes in blood serum of patients with schizophrenia. A comprehensive clinical and laboratory examination was conducted in 94 patients with schizophrenia (43 men and 51 women) and 43 healthy individuals. A statistically significant increase in the level of triglycerides (p = 0.040) and a decrease in the concentration of high-density lipoproteins (p <0.001) in schizophrenia compared with the control group was revealed. The revealed disorders increase the risk of occurrence of cardiovascular diseases and atherosclerosis in patients with schizophrenia, therefore, therefore, it is necessary to monitor the lipid spectrum of patients during antipsychotic therapy.