SCIENTIFIC REASONS FOR APPOINTMENT TO YOUNG GROWTH OF PRODUCTIVE ANIMAL BIOACTIVE ADDITIVES IN THE CONDITIONS OF THE SELENIUM-POOR REGION
As the territory of the Chuvash Republic refers to the high-risk areas of selenium deficiency, and the levels of trace element in the biological material of the population below the physiological norm, the development and introduction into production the methods of correction morphological status of man and animals selenium bio-additives is of great importance not only for modern physiology and elementology, but also for the economy of the country. The influence selenoorganic drugs: DAFS-25 and «Selenopiran» on hematological and biochemical parameters of calves of milk period, taking into account the biogeochemical features of the Chuvash Republic is studied. The authors conducted four series of scientific and economic experiments involving 80 calves-analogues. The excess number of erythrocytes (P<0.01) and level of albumin and gamma-globulins (P<0.05-0.001) in calves treated with DAPS-25 and «Selenopiran» is established. Growth of concentration of immunoglobulins at experimental calfs throughout researches is recorded. The intensity of lipid peroxidation was significantly higher at calfs from group of control, and activity of antioxidant system of experimental animals. In the conditions of the lowered temperatures the effect of the studied medicines was more expressed. It is proved that the calves on adaptive technology in terms of high and low temperatures on the background of the main diet with the use of DAFS-25 and «Selenopiran» had a favorable effect on the character of metabolic processes, lipid metabolism, hematological and immunological profiles of the animals. It was accompanied by a pronounced anti-stress and immunomodulatory effects. We recommend the use of these drugs in the practice of animal husbandry in the selenium-poor regions.