How to Increase the Eradication Therapy Effectiveness in Russia
The basis for the treatment of diseases associated with Helicobacter pylori is the elimination (eradication) of this infection. The effectiveness of the designated schemes of eradication should reach 90-95%, however, everywhere its significant decrease is being observed. The main reason for this is the formation of H. pylori resistance to antibiotics used in eradication regimens, primarily to clarithromycin, metronidazole, and levofloxacin. Several ways to improve the effectiveness of treatment are offered. One of them is the addition to the triple therapy of bismuth tripotassium dicitrate. It is shown that bismuth helps to overcome the resistance of H. pylori to clarithromycin and levofloxacin and reduces the frequency of antibiotic-associated diarrhea.