METABOLIC INDICES DYNAMICS VERIFYING THE CONTINUITY OF PATHOLOGIC PROCESS PROGRESSION IN MULTIPLE SCLEROSIS
The article gives an analysis of the metabolic dynamics verifying protein and lipid free-radical oxidation (FRO) intensification and a functional imbalance in the enzymatic and nonenzymatic segments of the antioxidant defense system (ADS), which identifies the presence of oxidative stress - one of the components of the complex pathogenesis of Multiple Sclerosis. The understanding of the complex pathogenesis of all clinical forms and phases of Multiple Sclerosis makes it possible to make a case for an effective pathogenetic therapy in the evidence-based practice, which is considered to be a basis for improvement of life quality of patients suffering from this serious disorder.