WERNICKE'S ENCEPHALOPATHY: OBSERVATIONS FROM PRACTICE
This article presents 2 clinical cases of Wernicke’s encephalopathy, first diagnosed in patients who do not abuse alcohol. Patients were examined and treated in the gastroenterological department of the Yakut Republican Clinical Hospital. Informed consent was obtained from patients for use of medical data for scientific purposes. The first patient had risk factors for the development of Wernicke’s encephalopathy: periodically occurring gastroenterological disorders, repeated vomiting and diarrhea, which contributed to the insufficient intake of thiamine, as well as the presence of malignancy, cancer intoxication and prolonged asthenia, as a result of combined chemo-radiotherapy. The disease manifested itself in the classical triad. In the second patient, Wernicke's encephalopathy developed on the background of severe vomiting of pregnancy, in the anamnesis of which she had terminated pregnancy twice a year for medical reasons. Initially, the disease was manifested by oculomotor disorders (nystagmus, ophthalmoplegia) and ataxia, and then a violation of mental status. Prescribe thiamine to prevent and treat a potentially devastating disease with brain damage that develops as a result of vitamin B1 deficiency in pregnant women with severe toxicosis in the first half gestation, patients with diseases manifested by indomitable repeated vomiting, as well as those who have undergone severe surgical interventions.