THE REMOTE RESULTS AND NATURE OF PROGRESSING OF TUMORAL PROCESS AFTER ADJYUVANTNY HIMIOLUCHEVY THERAPY OF A CANCER OF A STOMACH
Gastric cancer patients T3-4N0-2M0 stages adjuvant conducted DHT mode accelerated fractionation with a splitting rate. Before the start of stage I and II introduced DHT endolymphatically 5 mg methotrexate and 1 every 4 days intraperitoneally 50 mg/m2 oxaliplatin ozonized glucose solution. Patients received chemotherapy adjuvant control scheme FOLFOX. In the study group a total of 10 mg of methotrexate administered 300 mg/m2 oxaliplatin and in control – 340 mg/m2 oxaliplatin, 4000 mg /m 2 of 5-fluorouracil and leucovorin in 1600 mg/m2. Combined use of methotrexate endolymphatically and intraperitoneal administration of platinum on ozonated glucose can increase survival by 30 %, reduce 2 times the number of loco – regional recurrence and distant metastasis by 1,7 times.