A one-pot synthesis of novel spirocyclic N,N''-dicycloalkyl pyrido[2,3-g] quinolines
Heterocyclization of N,N'-dicycloalkyl p-phenylenediamines by cyclic β-diketones and formaldehyde under mild conditions leads to new N,N'-dicycloalkyl pyrido[2,3-g]quinolone spirocyclic derivatives, structurally similar to famous bioactive compounds. The synthesized azaheterocycles are expected to be enzyme inhibitors, antagonizers of the E1 prostaglandin receptor.