CLINICAL AND PATHOLOGICAL ASPECTS OF GASTROINTESTINAL STROMAL TUMORS
Gastrointestinal stromal tumors are a rare group of tumors with borderline malignancy which microscopically was seen as leiomyoma, leiomyosarcoma or schwannoma. The main predictor of gastrointestinal stromal tumors is the expression of the marker CD117 and CD34. The discovery of other markers is of less diagnostic value. On the prognosis of gastrointestinal stromal tumors is influenced by such factors as tumor localization, its size and the number of mitoses in 50 fields of view. In the article the results of treatment of 38 cases with localization in the stomach (20), small intestine (6), colon (9), retroperitoneum, and pancreas (3). Treatment included removal of the tumor and the appointment of Imatinib at high risk of progression. There were no postoperative complications. Mortality was 4 in a period of 1 year to 2 years.