The use of local ozone therapy in complex treatment of patients with various forms of erysipelas
The objective. To study the possibilities of correcting microcirculatory disorders in the area of inflammation in erysipelas with the help of local ozone therapy. Patients and methods. The examination included 73 patients with various forms of erysipelas. The patients of the first group (n = 35) along with basic therapy received local ozone therapy procedures, the patients of the control group (n = 38) received only basic therapy. As a criterion of effectiveness, we compared skin microcirculation before and after treatment. Assessment of microcirculation in the lesion areas was performed by the method of laser Doppler flowmetry (LDF) on the device «LAKK-02» and thermographic examination of the lower extremities on the device «IRTIS-2000». Results. Patients of the basic group, by the end of the course of treatment had a marked increase of microcirculation (increase of the microcirculation efficiency index to 1.89 ± 0.14 rel. units), a decrease of the microcirculation rate М enhanced due to inflammatory process (2.54 ± 0.18 perf. units.) as compared with the corresponding parameters of patients of the control group (MEI - 1.12 ± 0.05 rel. units, М - 4.16 ± 0.26 perf. units; p < 0.05); also, diminution of oedema of the affected extremity by 3.6 ± 0.22 cm was noted in the basic group, and by 1.4 ± 0.3 cm in the control group, p < 0.05. Conclusion. The use of local ozone therapy in complex treatment of erysipelas results in activation of microcirculation and, as a consequence, to acceleration of reparative processes, arrest of local inflammatory process.