SOLUBILITY OF DIFFERENT CALCIUM PREPARATIONS DEPENDING ON MEDIUM ACIDITY
The pharmacokinetic parameters of oral calcium (Ca) preparations substantially depend on the gastrointestinal tract, primarily on gastric acidity, as confirmed by the comparative analysis of the solubility of inorganic (first-generation) and organic (second-generation) Ca preparations. The organic Ca preparations better dissolve in water and far less depend on the pH of gastric juice, which considerably increases Ca absorption in the body.