Opportunities of using prothrombin complex concentrate Prothromplex in clinical practice
Hematological Research Center RAMS1; Clinical Pediatric Center № 32, Moscow, Russia Prothromplex contains coagulation factors II, VII, IX and X and primarily was intended for treatment and prophylaxis of bleedings in acquired prothrombin complex deficiencies which may occur in patients receiving oral anticoagulant therapy, in those with impaired liver function and vitamin K deficiency. If specific factor concentrates are unavailable, Prothromplex can also be used for replacement therapy in congenital prothrombin complex deficiency states, especially in haemophilia B and congenital factor VII deficiency.