ВПЛИВ ВІТАМІНУ С НА МЕХАНІЗМИ ЦИТОПРОТЕКЦІЇ ТА АКТИВНІСТЬ NO-СИНТАЗ У СЛИЗОВІЙ ОБОЛОНЦІ ШЛУНКА ТА ТОВСТОЇ КИШКИ У ЩУРІВ ЗА УМОВИ АДРЕНАЛІН- ІНДУКОВАНОГО СТРЕСУ
In investigations on rats the impact of vitamin C administered alone and on the background of iNOS blockade on parameters of the system L-Arginine/NO-synthases /NO in the gastric mucosa and the mucosal membrane of large intestine under conditions of epinephrine-induced stress was studied. It was shown, that vitamin C exerted cytoprotective effect, in stress possessed cytoptrotective action, inhibited the activity of iNOS, decreased the level of nitrite-anion, tiobarbituric acid products and superoxide dismutase activity.