NOS and аrginase inhibitors influence on myometrial contractility index in conditions of experimental immune ovarian disease at mice
It has been estimated the NOS and аrginase inhibitor’s influence on myometrial contractility index (CI) in conditions of experimental ovarian disease at mice. It is showed, that СI in conditions of experimental immune ovarian disease and oppressions of all NOS specifically block iNOS and аrginase changes in comparison with normal animal СI. Thus confirming the thesis that during pregnancy, through change of аrginase activity and, adjusting the general (common) nitric oxide production, mitochondrions coud be involved in change of myometrial contractility. The received results confirm nitric oxide participation in regulation of reproductive function, namely in maintenance the uterus myometrial contractility in conditions of change of the immune status of an organism.