Changes in periodontal tissues, tooth sensitivity and mucosal immunity when using toothpaste with hydroxyapatite, papain, thermal mud, extracts of eleutherococcus and calendula
We studied the dynamics of changes in periodontal tissues, tooth sensitivity, as well as the state of mucosal immunity when using the ASEPTA® Remineralization toothbrush (Vertex Co., St. Petersburg, Russia) in adults. It has been shown that the continuous use of ASEPTA<sup>®</sup> Remineralization toothpaste with hydroxyapatite, thermal mud, the plant enzyme papain, extracts of eleutherococcus and calendula after performing professional oral hygiene eliminates inflammation in the gums and dental hyperesthesia, ensuring good individual oral hygiene, normalization the balance of pro-inflammatory and anti-inflammatory cytokines with a shift towards a decrease in the concentration of pro-inflammatory cytokines, as well as an increase in the synthesis of secretory immunoglobulin A, which allows us to recommend this toothpaste for people with inflammatory periodontal pathology and dental hyperesthesia.