WOUND DRESSING WITH CHLORHEXIDINE BIGLUCONATE AND METRONIDAZOLE FOR WOUNDS
The article presents the results of an experimental treatment of chronic inflammatory diseases of soft tissues using a wound dressing (membrane) containing chlorhexidine digluconate and metronidazole in comparison with the official ointment «Levomekol». Experiments were performed on 108 white male rats Wistar. On the basis of microbiological, planimetry, histological research methods and statistical data processing it has been proved that the use of our developed formulation in the treatment of purulent wounds has a marked healing effect. Results of the study confirmed the efficacy of wound dressing due to the high adsorption activity, prolonged antimicrobial effect of chlorhexidine bigluconate and metronidazole, stimulation of tissue regeneration.