DYNAMICS OF CLINICAL MANIFESTATIONS AFTER SURGERY IN PATIENTS WITH MOYA-MOYA DISEASE
Introduction. Moya-moya disease is a progressive disease resulting in bilateral stenotic occlusion of the cerebral arteries. In recent years, there has been an increase in the number of studies focused on moya-moya disease. Unfortunately, there are no data on moya-moya disease therapy in Kazakhstan. Low awareness, in turn, leads to a delay in establishing an accurate diagnosis for patients with moya-moya disease. Methods. The study included 25 patients diagnosed with moya-moya disease who were treated at the National Center for Neurosurgery for the period from 2013 to 2020. The study is retrospective and descriptive. The analysis included the following patient characteristics: gender, age at the time of diagnosis, number of surgical interventions, clinical manifestations of the disease, treatment performed and its results. The dynamics was assessed using the Rankin and Bartel scales. Results. The primary manifestations of the disease are characterized by ischemic stroke (36%), hemorrhagic stroke (28%), headache (20%), TIA (8%) and seizures (8%). 13 patients underwent surgical treatment on the vessels on one side, the remaining 12 patients underwent surgery on both sides, depending on the side and severity of the clinical manifestations of the affected arteries. According to the Rankin scale, in the year of the operation, there are 16% of patients without disabilities. In 2020, they became 43.5%. On the Bartel scale, there is an identical positive trend. In the year of surgery, there were 48% independent patients, and in 2020 the number increased sharply, the figure reached 78.3%. Conclusion. According to our series of observations, the main clinical manifestation in 36% was ischemic strokes. Other manifestations are less common. There is a clear positive dynamics after surgical revascularization of patients. The performed surgical treatment made it possible to prevent the development of disease progression and the appearance of repeated clinical manifestations of cerebrovascular insufficiency.