THE FEATURES OF AMINO ACIDS L-ORNITHINE AND L-ARGININE INFLUENCE ON RENAL FUNCTION IN RATS WITH ACUTE TOXIC HEPATITIS
On the background of acute tetrachlormethane intoxication at a dose of 2 ml×kg <sup>-1</sup> of body weight the development of renal failure manifested by a decrease in daily urine flow, glomerular filtration rate, increase of creatinine in both serum and urine and reduction of its excretion was observed in experimental animals. Application of L-ornithine (1000 mg×kg <sup>-1</sup>) and L-arginine (500 mg×kg <sup>-1</sup>) leads to the positive impact on renal function, with the greatest efficiency observed at their combined usage.