Ethiology and pathogenesis of amyloidoses: the molecular and genetic basis
I he modern concepts of molecular and genetic basis of amyloidoses are considered in the brief review. The problems of classification, the common principles of amyloid formation, the mechanisms of fibrillogenesis and causes of tissue degeneration are discussed. The examples of certain amyloidoses are presented. The great attention is devoted to the hereditary forms of these diseases. The modern approach to diagnostics and therapy of different amyloidoses are discussed.