DEPENDENCE OF BRONCHIAL ASTHMA IN CHILDREN CLINICAL AND LABORATORY INDICATORS FROM POPULATED AREAS’ SIZE (ON EXAMPLE OF GRODNO REGION OF BELARUS)
The aim of the work is to identify the prevalence of bronchial asthma in children living in populated areas of the Grodno Region, and to establish the necessary volumes of clinical and biochemical studies and criteria for their evaluation. Laboratory indicators of dispensary-observating children with bronchial asthma and morbidity’s data in the city of Grodno and the Grodno Region revealed tendency to increase the disease prevalence. This is associated with an increase in the quality of diagnosis of the disease, as well as an increase in the influence of adverse factors provoking the onset and development of the disease. 281 patients were examined, regularities confirming the role of the socio-ecological environment in disease’s occurrence and spread were identified. Clinical and laboratory diagnostics included hemogram indicators assessment, biochemical blood examination, spirometry, general IgE detection. Differences in the course of disease (changes in external respiration rates, absolute number of blood cells) in children living in the city of Grodno (population 360 thousand people), in cities of the Region (population from 10 to 100 thousand people) and in rural areas of the Grodno Region were revealed. The influence of environmental conditions (plants/factories and their specialization in the territory, transport, food conditions) and behavioral stereotypes are expressed in children depending on the size of the settlement (place of residence) and affect the causes of the occurrence and manifestation of the bronchial asthma.