REGIONAL FEATURES OF THE PREVALENCE OF ALOPECIA AREATA AND ITS DEPENDENCE ON THE EXPOSURE LEVEL TO ENVIRONMENTAL RISK FACTORS
An epidemiological assessment of the results of the development of autoimmune skin diseases using the example of alopecia areata confirmed the hypothesis of the mechanism of formation of an average risk under conditions of high exposure of heavy metals in environmental objects, since the relative risks characterizing the relationship of morbidity with exposure to pollutants wos 1.6 units. A direct correlation dependence has been established between the number of cases of alopecia areata in the population and the level of complex anthropogenic load in the territories of their residence. On the basis of logistic regression analysis, a mathematical model for the development of alopecia areata depending on the exposure of heavy metals in the soil has been developed and it has been shown that an increase in the aggregate index of the content of copper, zinc and lead in the soil by 1 unit would lead to an increase in the likelihood of an indicator of the incidence of alopecia areata exceeding the average level by 4.3-1.1 %, and an increase in the aggregate index of the content of nickel and chromium in the soil by 1 unit would increase the probability by 1.6±0.3 %.