Study parameters of safety checkers from pine oil
The introduction to veterinary practice the new drugs makes high demands on the study of the toxicity associated with the proposed scheme of it use. The results of study the toxicity of thermo-sublimating smoke checker "Tambei" (OOO "Sanvetpreparat plus", Russia), containing as an active ingredient fir oil, are presented in the paper. Acute & sub-chronic toxicity were evaluated by inhalation route of administration in the exposure chamber on white mice and rats, respectively. Discovered LC<sub>50</sub> concentration, which is equal to 98±6,80 mg/l. permits to attribute the thermo-sublima-ting smoke checker to the 3 hazard class for inhalants. The drug had no effect on the general clinical condition, behavior and function status of the main body systems of laboratory animals, but as shown histological examination, it caused a slight irritating effect on the mucous membrane of the trachea and lungs of rats which probably was attribute to the combined effect of high concentrations of thermo-sublimating mixture and pine oil spray.