Thrombotic thrombocytopenic purpura (or Moshkovitz syndrome) under the mask of leptospirosis (case study)
Thrombotic thrombocytopenic purpura (TTP) is very rare disease which demands a careful differential diagnosis between systemic blood diseases (megaloblastic anemia, Evans syndrome, paroxysmal nocturnal hemoglobinuria, hereditary poikilocytosis), diffuse connective tissue diseases (systemic lupus erythematosus), hemolytic-uremic syndrome, DIC, catastrophic antiphospholipid syndrome. Among infectious pathologies similar changes can occur in septicemia (especially in case of DIC). But only in few places in the literature it is mentioned that the TTP is clinically very similar to the manifestations of severe course of leptospirosis.