EFFECT OF ULTRA-LOW DOSES ASPIRIN, ACETYLSALICYLATE COBALT AND ZINC ON PAIN SENSITIVITY RATS
In work it is researched analgesic effects ultra-low doses (40·10-8, 40·10-10, 40·10-13 mg/kg) of aspirin, acetylsalicylate of cobalt and zinc. All the tested compounds exerted analgesic effect, the largest - revealed by the action of zinc acetylsalicylate in a dose of 40·10-8 mg/kg. It is established analgesic effect ultra-small doses of cobalt acetylsalicylate, is not characteristic for its therapeutic dose (40 mg/kg). It was found that acetylsalicylate cobalt and zinc in a dose of 40·10-8 mg/kg superior to therapeutic and ultra-small doses of aspirin in analgesic effectiveness.