Features of changes in the hemodynamic characteristics of the main and tissue blood flow in the pathological tortuosity of the internal carotid arteries according to phase-contrast and perfusion magnetic resonance imaging
Objective. To analyze the peculiarities of changes in the main and perfusion blood flow in case of the pathological tortuosity of the internal carotid artery (ICA) using phase-contrast and perfusion MRI. Material and methods. The study was carried out on the MR-tomograph 1,5 T using a routine protocol, phase contrast and perfusion MR angiography. Focal vascular changes in the brain, indicators of volumetric, linear peak blood flow velocity by the ICA and the values of perfusion characteristics (CBF, CBV, MTT) in its pool were assessed. Results. The values of the velocity characteristics of the blood flow during the deformation of the ICA, accompanied by the appearance of MR-signs of cerebrovascular insufficiency, were determined; the interrelation of a significant decrease in the blood flow rate and an increase in the severity of dyscirculatory focal brain pathology in the pathology group was revealed. The correlation connections between the values of the bulk velocity of the main blood flow and the regional rate of tissue blood flow were revealed: the frontal lobe of the frontal lobe R = 0.35, the parietal cortex of the parietal lobe R = 0.62, the white matter of the frontal lobe is R = 0.32, the white matter of the parietal lobe is R = 0.33. Conclusions. Correlations between capillary and main blood flow demonstrate the possibility of using indicators such as blood flow velocity and CBF to assess the main and tissue hemodynamics in assessing the significance of pathological.