Experimental approbation of osteointegrational properties of implant's coating with biodegradable membrane from nanoaggregates of flafonoids
Characteristics of the new coating implantable materials obtained by induction heat-treatment and modified nanoaggregates flavonoids, as well as identified the prospects for their use in dental implantology dogs is described in this article. The authors found that the concentration of substances: Propolis - 1.25 mg/ ml of active material, a polymer - no more than 0.0001% is necessary for the formation of a non-toxic biofunctional coatings on the surface of the implant materials, the following should be used. Studies have shown that the experimental coating implants do not exert inhibitory action as erythromycin and on leucopoiesis, and the absence of sharp fluctuations in the level of calcium and phosphorus, bilirubin, creatinine and urea, the recovery of the initial activity of AST, ALT and minimum values of C-reactive protein animals of the experimental group in the early stages indicates the absence of toxic effects on the body of experimental implants.