Disaccharide insufficiency in children
The malabsorption syndrome is a complex of clinical manifestations appearing as a result of disorders of abdominal, parietal, membrane digestion and transportation mechanisms in the small intestine that lead to altered metabolism. In Russia, the most common form of the malabsorption syndrome in children is intolerance of disaccharides, first of all, of lactose, more rarely - of other carbohydrates. Most often, disaccharide insufficiency occurs in pathologies of the small intestine and is associated with functional defects of enzymes produced by enterocytes. Disorders of parietal hydrolysis of sugars and absorption of metabolites might be primary (inherited, congenital) or secondary - on the background of various diseases. The lecture dwells on current views on the pathogenesis, clinical picture, diagnosing and treatment of lactase insufficiency in children.