FREQUENCY OF THE MICRONUCLEI OCCURRENCE IN THE ERYTHROCYTES OF THE THREE-BRED RABBIT CROSS AT DIFFERENT STAINING TECHNIQUES
Rabbit breeding is a branch of the animal breeding with high opportunities for rapid increase in production rate and amount relatively cheap meat. The effectiveness of the animal breeding depends essentially on the genetic welfare of the pedigree animals. The results of the abundant investigations tell that the impairment of the reproductive function of the agricultural animals the along with the neonatal mortality are the main challenges in the further improvement of the animal breeding productivity. The genetic instability of the stud animals both of genetic and of paratypic origin makes a great contribution in these negative phenomena. The first investigations of the mutation spectra in the somatic cells and cytogenetic examinations were performed in the 20-th century. In 1973 W. Schmid proposed a micronucleus test. The test is one of the informative and prompt methods for examination of cytogenetic damages. It is based on the estimation of numbers of the cells containing micronuclei, which are the indicator of environmental genotoxic factors impact. The test involves the erythrocytes or some other highly specialized cells of a live organism. Techniques of micronucleus testing in rabbits is underinvestigated, so the main aim of the authors was a comparative analysis of the effectiveness of various staining techniques for blood smears to reveal the micronuclei in the erythrocytes.