The histological structure of white rats tibia middle diaphysis under the impact of the different modes of chronic hypertermia in combination with the physical activity
In an experiment on 270 white adult rat males it is set that influence of chronic hypertermia of the middle and extreme modes brings to the decline of diaphysis compact matter area, diminishing of width of outward general plates area, osteon layer, diameters of osteons, and the diameter of ductings of osteons, area of bone-cerebral cavity, width of area of internal general plates, vice versa, increase. Combined influence of chronic hypertermia and physical activity worsens studied indicators. Injection of inosine in a dose 20 mg/kg per day decreases negative influence of chronic hypertermia. During the readaptation the indicators in studied groups approach control values. The best leveling of studied deviatons was observed in groups, where inosine was used.