New ischemic syndromes" are new aims for cardiologists. Message 1
For two decades, the pathophysiology of the so-called new ischemic syndromes (stunning, hibernation, ischemic preconditioning) in patients with angina pectoris and, more importantly, with acute coronary syndrome (ACS) is studied. It is shown that myocardial viability can be divided into two stages, the first of which is an adaptive reaction to hypoxia (the phase of "survival") - a short- term protective reaction, which most often occurs during angina attack (from 5 to 15 minutes), followed by multi-hour decrease of local contractility of myocardial segments, which is called "stunning", "hibernation" and "ischemic preconditioning".The difference in the nature of their course, the types of these changes called "new ischemic syndromes" are described in detail in this article.