COMPARATIVE EVALUATION CLINICAL AND IMMUNOLOGICAL PARAMETERS OF PATIENTS WITH CYTOMEGALOVIRUS AND CAUSED BY EPSTEIN – BARR VIRUS INFECTIONS
Patients with CMV and EBV is not revealed pathognomonic symptoms characteristic of each of our infections, tonsillitis, except that significantly more registered with CMV. Concomitant bacterial infections, abrasions, fungal infections, and autoimmune syndrome were more frequently observed in patients with EBV. Complicated obstetrical history was recorded more frequently in women with CMV infection. Patients in both groups compared to the control lymphoid reduced proportion of cells expressing markers of the early (CD25 +) and late (HLA-DR +) lymphocyte activation, which indicates that inhibition of the cytotoxic effector phase of an immune response. Patients with EBV infection compared with patients with CMV infection was significantly higher proportion and absolute number of CD3 + -lymphocytes, the absolute number of CD4 + -, CD95 + - and HLA-DR + -lymphocytes, a smaller proportion of CD25 + -lymphocytes. In patients with CMV infection compared with patients with EBV infection following indicators neutrophil phagocytic activity, but above the spontaneous activation of neutrophils and the level of Ig M.