Circadian rhythms of cell population structure of Rauwolfia serpentina Benth. under different culture conditions in vitro
A thermodynamic approach has been used to study dependence between the incidence of cells with various DNA content in nucleus and the proliferation rate (mitoses and amitoses). These biological fluxes and forces have been analyzed at the circadian hierarchic level upon changes in the culture conditions for the Rauwolfia serpentina K-27 strain, a producent of the anti-arrhythmic alkaloid ajmaline.