Magnetic Resonance Diffusion in Diagnostic Metastatic Lesion of Axial Skeleton: Preliminary Results
We have made the analysis to estimate the experience of whole body diffusion weighted imaging for diagnosing bony lesion of oncology patients. 107 patients were examined: 86 of them - control group, 21 - with verified bony metastasis. Summary we have done 526 measurements of apparent coefficient diffusion (ADC) value in normal bone tissue, in verified bone metastatic lesion and in suspected bone metastatic lesions. As it is known, isolated application DWI without ADC has very poor diagnostic possibilities. It is very important to take into account the ADC value. The average value in the control group was 0,52 ± 0,10 × 10-3 мм2/s and it was statistically less than in the group with bone metastases - 1,43 ± 0,54 × 10-3 мм2/s (p < 0,0001). The whole-body diffusion weighted imaging showed highly potential results in identifying both differential diagnostic metastatic and non-neoplastic bone lesions. Average ADC value in normal bone tissue and bone metastases statistically demonstrate significant differences.