Health and Economic Project of Introduction Insulin Pump Therapy in Republic of Kazakhstan
The article describes the health- economic approaches to assess the effectiveness of the implementation of insulin pump therapy in the Republic of Kazakhstan for the treatment of type 1 diabetes on the basis of health-economic analysis. Analysis determines the relevance of cost-effectiveness of certain treatments for diabetes, along with the efficient and effective expenditure of funds for the treatment of these patients in order to reduce its complications and improve quality of life for patients. Core Diabetes model is described to determine the economic impact of the use of insulin pumps in the treatment of type 1 diabetes compared with MDI (multiple daily injections). It was used to simulate disease progression in a cohort of adult patients with baseline characteristics and costs taken from primary data collection in KAZAKHSTAN (mean age 39.7 years, duration of diabetes 10.1 years and mean HbA1c 8.5%). Clinical outcomes (HbA1c and hypoglycemic events) were taken from a published meta-analysis of CSII studies. Direct costs for 2013 were calculated from a third-party payer perspective. Discount rates of 5% per annum were applied to costs and 3% to clinical outcomes.