MOLECULAR DETERMINANTS OF THE DEVELOPMENT OF EARLY AND LATE PREECLAMPSIA
The article discusses the molecular biological aspects of two clinical variants of preeclampsia (early- and late-onset preeclampsia), the specific features of the expression of different molecules involved in the development of preeclampsia, including the concentrations of vascular endothelial growth factor, placental growth factor, vascular endothelial growth factor receptor-1, epidermal growth factor, transforming growth factor-β, vascular cell adhesion molecules, toll-like receptor, serum pentraxin 3, soluble endoglin, and the expressions of different mRNAs.