THE RESULTS OF THE MEASUREMENT OF N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE AND ECHOCARDIOGRAPHY ASSESMENT IN WOMEN WITH DIABETES MELLITUS
Object of research - 25 women with diabetes type 2 were examined (45 to 65 years old). All patients have heart failure and coronary artery disease. Aim - to study NT-proBNP level and to analyze echocardiography parameters in patients with or without myocardial infarction. Methods. NT-proBNP plasma level was measured by enzyme-linked immuno sorbent assay. Echocardiography was performed to determine the left ventricular end-diastolic and end-systolic diameter (LVEDD) and left ventricular ejection fraction (LVEF). Transmitral flow was measured. Results. All patients have myocardial hypertrophy with left ventricular ejection fraction (LVEF) > 40 %. NT-proBNP was significantly higher in patients with diabetes mellitus and correlation between NT-proBNP and LVEF (r = -0,174; p = 0,051) was revealed. Conclusion. All women with diabetes mellitus type 2 had hypertrophy of LV, diastolic dysfunction and normal LVEF. The eccentric LV hypertrophy was more often in patients after myocardial infarction.