Analysis of Long-Term Results of Colorectal Cancer Liver Metastasis Patients Applying International Data Base LiverMetSurvey
The international database LiverMetSurvey was created for analysis of surgical treatment in patients with colorectal liver metastasizes. It includes information about 16 779 patients from the different countries of the world. 272 patients were operated and analysed in the RNRCS of RAMSci. The comparative analysis of survival rate was carried out on 8 factors. The highest 4-year survival rate was in patients with unilobar metastasis, which diameter does not exceed 30 mm, total number is not more than three, and there is no evidence for extrahepatic spread. In the RNRCS advanced disease was diagnosed more often, and 35% of patients were treated with additional surgical methods (vs 22% LiverMetSurvey). Preoperative chemotherapy didn't worsen the long-term results in patients from NRCS (4-year survival rate was 34.7vs 35.3% without chemotherapy, p = 0.247). According to LiverMetSurvey chemotherapy had prognostic value, and reducing the survival rate from 53 % to 48%, p < 0.0001. The long-term results after use of the combined surgical methods (RFA and portal vein occlusion) were comparable with group of patients where they did not used. In LiverMetSurvey the 4-year survival rate was lower, if liver resection was combined with RFA (43% vs 52%, p < 0.0001) or performed as second stage after portal vein occlusion (39% vs 52 %, p < 0.0001). Results of the study showed relative high level of specialised medical care in single surgical center.