Prolactin, cortisol, testosterone and dehydroepiandrosterone blood plasma levels in psoriasis patients
Endocrine disorders play an important part in psoriasis although publications covering the role of hormones in psoriasis are scarce and controversial. Only recently have hormones' pathogenetic functions started to attract systematic investigations attention. Prolactin, сortisol, testosterone and dehydroepiandrosterone blood plasma levels were studied by means of immune-enzyme method in psoriasis vulgaris patients in comparison to healthy individuals. Cortisol and dehydroepiandrosterone levels in both male and female psoriasis patients proved to be validly increased. No valid difference in the studied hormones' concentrations dependent on the stage of the disease was revealed. Peculiar changes of certain studied hormones have been found with different trends in male and female patients that might be involved in the pathogenesis of psoriasis. Among other hormones prolactin concentration changes appear to be one of the crucial pathogenetic factors in psoriasis.