Modern aspects of epidemiology of ticks transmitted infections
Modern literature data have changed our imaginations about the etiological "landscape" of the diseases arising after the suction biting of ticks. The possibility of transmitting mixt-infections by ticks has become an important scientific and practical problem. Ticks can be infected by the all 7 found pathogens (TBE virus, 3 species of Borrelia, Ehrlichia, Anaplasma, Babesia). Among ticks with the modified morphology monoinfected individuals occur 1.3 times, biinfected - 1.5 times more frequently, and the cases of triple infection appear twice more often than among normal cases. There were formed new ideas about genotypic and phenotypic heterogeneity of natural populations of tick-borne virus, there is discussed the heterogeneity of the genome and the pathogenic properties of the TBE virus. There was performed the analysis of literature data about the multifacetedness of the genetic polymorphism typical for the genus Borrelia in total, observed phenomena of the discrepancy of the spectrum of genospecies of Borrelia in natural foci and in biological materials from patients, complex antagonistic tolerant or symbiotic interactions between various intracellular and extracellular pathogens carried by ticks, in the vector's body, reservoir hosts and macroorganism.