Results of a clinical study comparing the efficacy and safety of Quifenadine and desloratadine in patients with allergic skin diseases
The results of the clinical study «Randomized, in parallel groups, active-controlled study for comparing the efficacy and safety of the medicine «Phencarolum» and desloratadine in patients with allergic skin diseases (atopic dermatitis, eczema, allergic contact dermatitis) « were considered in the article. Objective of the study: to determine the safety and efficacy of the medicine «Phencarolum» in comparison with desloratadine in patients with allergic skin diseases. Object of the study: allergic dermatoses. Methods of investigation: assessment of severity of allergic dermatoses, itching, life quality and psychological state of patients. Results of the study: the safety of long-term use of the medicine «Phencarolum» was proved. The advantages of using Phencarolum in comparison with desloratadine in the treatment of allergic dermatoses were shown, they were confirmed by statistically significant differences in the scoring on the SCORAD, ΔSCORAD (%), the severity of itching and excoriations between the groups of patients after completion of the treatment course. The indirect positive effect of Phencarolum on the life quality was proved. Conclusion: Phencarolum is a more effective antihistamine in the treatment of allergic dermatoses compared with desloratadine.