Clinical and Pathophysiological Concepts of Hepatoprotective Therapy in Young Patients
We assessed the efficacy of essential phospholipids and methionine in the treatment of hepatic disorders. In our study, we examined a group of 46 young patients with nonalcoholic fatty-liver disease who received these medications. Compared to baseline, this therapy inhibited cytolysis and reduced mesenchymal reaction, inflammation and cholestasis in all patients. In addition, these medications showed a hypolipidemic effect, mostly accounted for by a decrease in LDL-cholesterol. This treatment decreased liver steatosis. The study demonstrated that essential phospholipids and methionine are highly effective in treating liver disorders in young patients.