Acute lung injury in patients with a viral and bacterial pneumonia against overweight and obesity
Acute lung injury (ALI) is a severe inflammatory condition that develops in patients with a serious current of community-acquired viral and bacterial pneumonia. Risk factors of development ALI are insufficiently defined till now. Results of epidemiological researches of last decade testify that adiposity is the important factor contributing to development ALI. Though the pathogenetic mechanisms binding adiposity and development ALI, are insufficiently clear, appears more and more scientific proofs specifying that biologically active factors consecrated by a fatty tissue (adipokines) make essential impact on physiology of lungs. Change of secretion of adipokines against adiposity promotes the raised predisposition to development ALI. In the present review attempt on the basis of results of researches of last decade is undertaken to answer a question: how the superfluous mass of a body and adiposity influence a functional condition of lungs.