FEATURES OF THE LOCAL INFLAMMATORY PROCESS IN PATIENTS WITH DIABETES AND CATARACTS
We examined 60 patients with diabetes mellitus and cataract (study group) and 20 healthy faces. The main group of patients divided into two subgroups. In a 1 subgroup included 30 patients who in postoperative performed standard anti-inflammatory local treatment. The second subgroup included 30 patients in the combined treatment which used the proposed scheme of conservative treatment based on the introduction to the region of microcirculation in the postoperative period, drugs with anti-inflammatory, anti-edematous, bioregulatory properties. Before surgery, in the lacrimal fluid patients with diabetes and cataracts identified high concentrations of proinflammatory cytokines IL-1β, the ratio of proinflammatory / antiinflammatory interleukins. Revealed the high level of markers of cell destruction - autoantibodies to native and denatured DNA and marker of activation of humoral immune system, circulating immune complexes. Showing pathogenetic significance and clinical-ophthalmology efficiency of the proposed method of conservative treatment Using the proposed combined treatment leads to a reduction in the activity of local immunoinflammatory process, reduces the frequency and severity of postoperative complications compared with standard treatment regimens.