Toxic Effect of Cytostatics on Changes in the Morphometric Parameters of the Retina and Choroid During Retinoblastoma Chemotherapy
In the study morphometric changes in the retina and choroid that occur during combined chemotherapy inpatients with retinoblastoma were studied. The results obtained indicate the presence of local toxic effects ofthe chemotherapy drug (melphalan) on the intact retina and choroid. Changes in the retina and choroid on the background of local chemotherapy determine the choice ofthe chemotherapeutic method strictly according to the indications and in compliance with the protocol (time intervals).