The CT-Perfusion, CT-Angiography and Duplex Scanning in the Diagnosis of Functional Disorders in Patients with Chiari Malformation 1 without Syringomyelia
Objective. Estimated using the method of CT perfusion clinical significance of changes in regional blood flow at the level of craniovertebral junction in children with Chiari malformation 1 (CM1). Material and methods. The study on the relationship of functional vascular disorders and headache in 17 patients with Chiari malformation 1 from 2 to 18 years by the methods of the duplex scanning (DS) and CT-angiography was conducted. The method of the CT perfusion was further used in this group of patients, to the objectification of the results obtained. Results. There is interrelation between parameters of CT brain perfusion and regression of headache in patients with CM1 without syringomyelia. There is correlation between the methods DS, CT-angiography and CT perfusion. Conclusions. The method of CT perfusion in patients with CM1 confirmed the assumption about the participation of functional vascular disorders of the craniovertebral junction in the pathogenesis of clinical manifestations. The findings of this study can be used in determining the indications for surgical treatment of patients with CA1 without syringomyelia.