THE STUDY OF ANTIATHEROGENIC AND ANGIO-PROTECTIVE EFFECT OF VENOTON CAPSULES IN HYPERVITAMINOSIS D MODEL
The results of studying angioprotective (antiatherogenic, hypolipidemic) and anti-oxidative action of Venoton capsules on the experimental model of hypervitaminosis D comparing to Eskuvit tablets. In the conditions of hypervitaminosis D Venoton corrected the disordered metabolic processes and showed antitoxic properties. A comparative analysis of pharmacotherapeutical efficacy of Venoton capsules and Eskuvit tablets has been conducted for the most informative indices in the conditions of hypervitami-nosis D, as well as peculiarities of their action on calcium exchange, lipid metabolism and the system of lipid peroxidation and anti-oxidant system in laboratory animals has been evaluated. It allowed to determine the most marked angioprotective (antiatherogenic, hypolipidemic) and anti-oxidative action of Venoton capsules. The pharmacological activity of Venoton capsules is provided by the complex composition of biologically active substances of seven medicinal plants, while a dry extract of chesnut fruit as a monocomponent in the composition of Eskuvit tablets cannot provide such intensity and comprehensive pharmacological action.