TESTING OF AVIAN INFLUENZA VIRUS HEMAGGLUTININ EXPRESSING CELO-H5 AND CELO-H7 ADENOVIRAL VECTORS IN COMMERCIAL CHICKS
Vaccination of commercial chicks with recombinant avian CELO adenoviruses expressing avian influenza virus (AIV) hemagglutinin induced strong immune response to subtypes H5 and H7 of avian influenza, which possessed protective properties. The highest immune response was observed at chicks' immunization with CELO-H5. Simultaneous administration of these constructs reduced the vaccination efficacy, though the immunity protective properties remained at a high level.