Cytomorphologic indicators of the hepatorenal system in laboratory animals at inhalation poisoning by elemental sulfur
The hepatorenal system at inhalation poisoning by elemental sulfur was studied in laboratory animals at concentrations of 1.76 and 12.68 mg/m3 during 15 days, 1, 2 and 4 months. Using cytomorphologic investigation methods, the most expressive disturbances in liver and kidneys cells were found out such as: pathologic processes in liver hepacytes; microtubular fatty degeneration encountered in light hepatocytes; were observed a decreased amount of dark cells and an increased amount of degenerated light cells and neutrophils. As to the sectoral function of kidney tubules, destructive changes in small and large light tubular cells were observed; albuminoid degeneration encountered in most of the cells, in particular, at inhalation at a dose of 1.76 mg/m3, within a month.