Positive and Problem Aspects of Rotavirus Vaccines Application
In the article we present the data on the rate of rotavirus infection (RVI) in the Russian Federation and provide the analysis of effects associated with application of rotavirus (RV) vaccines in countries with long-term application experience and raise the questions related to implementation of RV vaccines in national vaccination calendars of different countries. The data on RVI morbidity, territorial distribution, age dynamics of infection on the territory of the Russian Federation and in regions with high RV circulation rate in particular are provided. The rate of nosocomial transmission of RVI in children’s infectious hospitals and the rate of RV RNA detection in lethal cases among children aged less five years is estimated. The [P]G typing results of 207 RV samples isolated in 10 cities of the Russian Federation within the period of 2011 - 2012 are shown (G4[P]8 - 50.5%; G1[P]8 -26.7%; G2[P]4 - 7.8%; G3[P]8 and G9[P]8 - 4.4% each). Major problems associated with implementation of RV vaccines in national vaccination calendars as well as possible ways of their resolution are presented in conclusion.