Age Features of Myeloperoxidase Activity, Neutrophil Elastase and Alkaline Phosphatase in Blood Serum in the Syndrome of Brittle Nails
We studied the neutrophilic granulocytes absolute content, myeloperoxidase, neutrophil elastase and blood alkaline phosphatase activity in 99 women of the different ages with nails brittle, onychoschizis, onycholysis and hyperkeratosis. The biochemical analysis show that nail plates brittle accompanied by increased activity of the myeloperoxidase and neutrophil elastase in the trand to reduce the blood leukocytes content in women older than 50 years and more a marked reduction of the blood alkaline phosphatase activity as compared to women younger than 40 years. The research results justify the need to use neutrophilic granulocytes functional activity findings including blood myeloperoxidase and elastase in diagnostics of the onychodystrophy with different genesis in women older than 50 years.