MIXED MICROBIAL ASSOCIATIONS THAT CONTAIN <i>CANDIDA</i> SPP. IN THE MICROBIOTA OF THE ORAL CAVITY OF CHILDREN WITH ONCOHEMATOLOGICAL DISEASES
In patients with oncohematological malignancies the oral microbiota often serves as a source of microorganisms causing local and systemic complications. Frequently, mixed communities that include different bacteria and fungi cause these complications. The use of chemotherapy during the treatment of oncohematological conditions results in depletion of microbiota and gives rise to multiresistant strains of microorganisms. In this study Candida-bacterial biofilms were isolated from saliva of children with oncohematological malignancies. These mixed communities have constant composition, readily reproducible in serial replating. Isolated Candida species show high resistance o antifungal drugs.