Influence of nanosized silica suspension on free radicals production and peroxidation processes in gastric mucousa of rats under combined nitrate and fluoride intoxication
The study was conducted on 52 adult Wistar rats for 30 days to examine the effect of combined nitrate and fluoride intoxication on the generation of superoxide anion radical («О?-), the functioning of enzymatic antioxidant systems, integrated indicator of antioxidant protection and indicators of lipid peroxidation (LPO) in rat gastric mucosa. Analysis of the results allowed us to establish a synergistic effect of fluoride and nitrate toxicity on processes of lipid peroxidation. The impact on the generation of »02- and antioxidant system has a complex interaction.