Morfologicheskih changes in cirrhotic liver after intrahepatic administration of cryoprecipitate and alloplant
Morphological changes in the liver tissue from 62 patients with cirrhosis of the liver virus ( HCV and NVsb ) and toxic etiology, before and after the administration of cryoprecipitate and alloplata. The age of the patients was 48,9 ± 12,14 ( from 25 to 68 years), there were 35 men (56 %), women - 27 ( 44%). In 34 of the 62 patients had cirrhosis of mixed etiology ( toxic and viral ), and 21 - viral, 7 - toxic. The patients were divided into two groups : Group 1 - 42 (out of 62) patients who had to stimulate regeneration of liver tissue was introduced cryoprecipitate, Group 2 - 20 (out of 62) of patients who were administered alloplant. Cryoprecipitate or alloplant injected percutaneously into the liver puncture method under ultrasound guidance. The results were evaluated before and one year after the introduction of cryoprecipitate and alloplant, performing a liver biopsy under ultrasound guidance. Reduction of the inflammatory cell infiltration and liver regeneration trusted signs were detected in 74 % of patients with cirrhosis of the Class A, B and C Child-Pugh cryoprecipitate after injection and 60% after administration allo-plant patients with cirrhosis of class A and B. Clinical manifestations of the disease significantly decreased after the introduction of cryoprecipitate. After the introduction of alloplant in 65% of patients grew cholestasis. Thus, the introduction of cryopre-cipitate in the liver, improves the clinical laboratory and morphological changes in patients with cirrhosis of Class A and B on the Child-Pugh, and prolongs the life of patients with cirrhosis of the liver class C Child-Pugh. Introduction alloplant effective in patients with cirrhosis of Class A and B on the Child-Pugh. In cirrhosis of the liver class C Child-Pugh - alloplant ineffective.