Selection of algorithms for evaluation the degree of severity of endotoxicosis during peritonitis
The algorithm estimates the degree of severe endotoxemia in peritonitis. List of main indicators that reflect the mechanism of endotoxemia made the following markers: the heart rate from 110 to 153 beats/min; systolic pressure of 70 to 120 mm Hg.; diastolic pressure between 40 and 70 mm Hg.; daily urine quantity of from 0 to 700 ml; urea from 11,2 to 25,4 mg/dL; the concentration of middle molecules in the blood of peptides from 0,43 to 60 standard units; malondialdehyde concentration in the blood from 205 to 300 mmol/l; concentration of diene conjugates in blood from 2,3 to 6,0 mmol/l; paramecium lifespan in peritoneal exudates from 600 to 1100; the concentration of malondialdehyde in the peritoneal exudates from 220 to 600 mmol/l; the concentration of hydroperoxides in the peritoneal exudates of from 0,25 to 0,5 mmol/l; concentration of diene conjugates in the peritoneal exudate of 3,15 to 5,5 unt/l; the concentration of catalase in the peritoneal exudate from 0,09 to 0,21 standard units; total antioxidant activity in peritoneal exudate from 5 to 27%; the concentration of middle molecules peptides in peritoneal exudate from 0,29 to 0,58 standard units. We believe that this algorithm not only characterizes the severity of endotoxemia but also has prognostic value.