CLINICAL FEATURES OF ATOPIC DERMATITIS ACCOUNTING THE CONTAMINATION OF THE FECES OF <i>CANDIDA</i> SPP. AND TOTAL IGE
The aim of this work was to study the state of the intestine mycobiota and the level of total IgE in patients with different forms of atopic dermatitis (AD). 167 patients with acute AD in age from 8 to 65 years were examined; the control group consisted of 24 apparently healthy individuals of the same age and gender. All patients were determined the degree of severity of AD according to the SCORAD index. The cultural investigation of the biosubstrates on Candida species was carried out on medium Saburo. The definition of the level of total IgE in patients with AD was done with ELISA. According to the SCORAD index in 53,3% of cases in patients with AD the severe degree of the disease was identified. The average level of total IgE in patients with various forms of AD was 4.9 as high as it was in the control group (P˂0,05). Increased intestinal colonization of Candida spp. was noted in patients with severe and moderate disease, which were often recorded at pruriginous and lichenoid forms. The correlation of intestinal contamination by Candida spp. with the degree of severity of AD was observed.