The insulin initiates "kinetic perfection" of biologic function of locomotion. The glucose as substratum for synthesis of ω-9 oleic fatty acid by cross-striated myocytes
The phylogenesis theory affords ground for the following propositions. 1. There is no absorption of glucose from intercellular medium by cells in vivo until there is possibility to absorb polar fatty acids from associates with albumin. 2. The late in phylogenesis humoral insulin regulates no stages of glucose metabolism; they are completed a billion years before hormone synthesis. 3. The phylogenetically late insulin is “hostage" of biological function of trophology, function of nutrition, biological reaction of exotrophy; it has no possibility to decrease in food excessed amount ofphysiologic palmitic saturated fatty acids with low kinetic parameters of β-oxidation in mitochondria. 4. The early in phylogenesis, resistant organizational to insulin pool of visceral fatty cells of omentum and late pool of insulin-dependent adipocytes are different in many functional parameters. 5. All “metabolic pandemics" such as syndrome of resistance to insulin, atherosclerosis, metabolic arterial hypertension, metabolic syndrome and obesity are primarily pathologies of fatty acids. 6. All “metabolic pandemics" are pathologies of one biological function, function of locomotion under single algorithm of formation of their pathogenesis. 7. The etiological factor of “metabolic pandemics" is uniform - effect of environmental factors in form of disorder of biological function of trophology, function of nutrition; aphysiological excess content in food ofpalmitic saturatedfatty acid, aphysiological trans-forms of fatty acids and ω-7- palmitoleic mono unsaturated fatty acid. The insulin activates absorption by myocytes, cardiomyocytes of glucose as substrate of synthesis out of it in situ de novo ω-9 oleic mono unsaturatedfatty acid. With such physical chemical parameters that mitochondria oxidize it with the most high constant of velocity of reaction and high effectiveness of formation of ATP.