DIAGNOSIS OF IRRITABLE BOWEL SYNDROME (clinical case)
Aim. Review of the latest data on pathogenesis and diagnosis of irritable bowel syndrome has been performed with presentation of personal clinical example. Material and methods. The following keywords have been used to select relevant articles in e-library and MedLine databases: «irritable bowel syndrome», «diagnostics», «pathogenesis»,«differential diagnostics». Medical history of the patient with irritable bowel syndrome has been analyzed. Results and discussion. Nowadays, genetic bases of the pathophysiology of irritable bowel syndrome as well as the interaction of endocrine cells of the gastrointestinal tract and enteric nervous system are being actively studied. Intestinal microbiome is being explored. Currently, the «gold» diagnostic standard is the Rome criteria, the IV revision of which was presented in May, 2016. Despite significant achievements in fundamental, clinical and epidemiological studies, the mechanisms of functional intestinal disorders development have not been fully studied and the newest version of Rome criteria allows diagnosing irritable bowel syndrome only clinically by excluding other diseases. In the presented clinical case diagnosis was made only after repeated consultations of different specialists, multiple diagnostic tests, by excluding more serious diseases. Conclusion. Despite the greatest prevalence of irritable bowel syndrome among all functional disorders, its diagnosis is associated with a substantial burden in healthcare resources.