Possibility Of Breast Conserving Surgery In Multicentric And Multifocal Breast Cancer (Review)
Objective of the study. To conduct a systematic analysis of the current literature data concerning possibility of breast-conserving surgery in multicentric (MC) and multifocal (MF) breast cancer. Material and Methods. The review includes the data of national and foreign literature, found in Web of Science, Pubmed and e-Library having been published. Results. There are presented the frequency of multicentric (MC) and multifocal (MF) breast cancer, frequency of regional lymph node involvement, indications and contraindications for breast-conserving surgery in multicentric breast cancer, long-term results after breast-conserving operations in comparison with mastectomies. It is shown the principal possibility of breast-conserving operations in MC/MF breast cancer. Conclusion. Conservative surgery in MF/MC breast cancer treatment is acceptable and reasonable in compliance with certain conditions: age 50 - 69 years, multifocal growth, size of the largest lesion < 1 cm. absence of DCIS, value of Kindex < 0.1%. Preoperative evaluation of all tumor foci is a must. The question of possibility of breast-conserving surgery must be discussed with the participation of surgeons, chemotherapeutist and radiologist.