The role of diabetes mellitus in the etiopathogenesis of urolithiasis
Purpose of the study was to study the incidence of diabetes in patients with urolithiasis in the Perm region with a population of 3.3 million people for 30 years. Materials and methods. 1475 patients with a combination of diabetes and urolithiasis, type 1 diabetes had 427 patients, type 2 - 1048 (71.7%). The method of infrared spectroscopy was used to determine the composition of stones. Results. It was found that among patients with urolithiasis has been steadily increasing the percentage of patients with diabetes, from 6.6% in 1988 to 16.2% in 2017. Resulting in diabetes, urinary stones more often (40, 2%) are uric acid, somewhat less (30,5%) calcium-oxalate stones. Metabolic disorders in diabetes lead to a sharp acidic urine reaction (pH 4.5-6.0), increased levels of uric acid and calcium in the blood and urine, which leads to the formation of stones. Conclusions. Diabetes mellitus is a risk factor for urolithiasis. Emerging stones are most often urate, which is important for metaprofection of stone formation