EPIDEMIOLOGICAL INDICATORS OF PRIMARY-MULTIPLE TUMORS (REVIEW OF LITERATURE)
The detection in the patient of more than one tumor in the same or different organ suggests that primary-multiple tumors may be present. Different concepts of multiple tumors are used for epidemiological research, with two main definitions taken from the International Association of Cancer Registers and the International Agency for Research on Cancer. The differences in these two definitions should be taken into account when analyzing reports for several basic criteria. This article reviews and summarizes some literary data on primary multiple malignant tumors - (PMZs). In general, frequency of PMSE is from 2-17%. The causes that can predispose patients to PMZO can be grouped into factors related to the person himself, lifestyle, and the influence of environmental conditions. General principles and possible options of treatment of patients with synchronous and metachronic primary multiple malignant tumors are identified.