AUTOIMMUNE THYROIDITIS, HYPOTHYROIDISM AND PARATHYROCRININ
The frequency of hypothyroidism, mainly caused by autoimmune thyroiditis (AIT), is increasing globally. In the clinical picture of hypothyroidism of various origins and hypoparathyroidism, there is a number of important common signs shared by these diseases that fit into the symptoms of a violation of phosphorus-calcium-magnesium metabolism, which is regulated by the parathyroid glands with the help of parathyrocrinin (parathyroid hormone). The catamnesis of 233 people with AIT aged from 5 to 87 years was studied. There were 25 men and 208 women. The levels of parathyrocrinin, TSH, FT3, FT4, autoantibodies to thyroid peroxidase, vitamin D3, ionized calcium, phosphate- anion and magnesium were determined. Bone densitometry was performed. The results were compared with the sex and age of the patients, with the levels of thyroid-stimulating and thyroid hormones, autoantibodies, vitamin D3. symptoms of hypothyroidism and with its severity. All patients had a decrease in bone mineral density corresponding to osteopenia or osteoporosis. A positive correlation of the level of parathyrocrinin with age, TSH, AB to TPO, ionized calcium, Ca++, negative - with vitamin D3, FT3, phosphorus (Bibliography; Figures; Table.).