INDIVIDUAL-TYPOLOGICAL APPROACH IN EVALUATION OF VITAMIN D CONTENT AND ITS ERGOGENIC EFFECTS IN WOMEN OF REPRODUCTIVE AGE IN PREGRAVIDARY PREPARATION
The development of a new direction in preventive medicine and obstetric practice requires the active development and implementation of effective comprehensive programs to optimize motor activity, increase the functional capabilities of the body and dynamic control of the content of vitamin D in the blood serum of women of reproductive age. Materials and methods. 133 patients aged 20-35 years with normal body weight (70 women of group I) and overweight (63 women of group II) had a consistent increase in the level of motor activity (mobile applications on Android and Apple platforms) by 1 cent for 7 days for 5-7 weeks, which was combined with the appointment of vitamin D (respectively at a dose of2000 ME/ day and 4000 ME/ day. The evaluation of the effectiveness of pregravidar preparation is given taking into account the dynamics of body weight, as well as the content of 25-hydroxyvitamin D in blood serum [25 (OH)D], total and ionized calcium, phosphorus and parathyroid hormone in comparison with the initial data. Results. In comparison with the initial data after pregravidar preparation using the author's algorithm for increasing motor activity and the appointment of vitamin D, unidirectional positive effects of exercise tolerance and the dynamics of phosphorus-calcium metabolism in both groups were established within the reference values, but with higher serum levels of total and ionized calcium, phosphorus and a decrease in parathyroid hormone in women with normal body weight compared with women with BMI. Conclusions. The combined use of the proposed daily physical activity with the appointment of vitamin D determined an increase in its content in blood serum, a decrease in body weight and an increase in the effectiveness ofpregnancy in women with a BMI of up to 52.3%, and in women with normal body weight up to 91.4%. A comparative analysis of the results of vitamin D content and its ergogenic effects in women of reproductive age allows for a consistent centile increase in the daily number of locomotions and the administration of vitamin D up to 10-12 weeks and the approximation of body weight to the upper limit of the regulatory corridor (75-90 cents) in women with BMI, taking into account their personal consent and under dynamic control of calcium-phosphorus metabolism.