The concentration of matrix metalloproteinase-9 at different outcome of uveitis complicated by inflammation of the optic nerve
The content of matrix metalloproteinase-9 in the blood of 127 patients with uveitis complicated by inflammation of the optic nerve.It is found that in the active stage of uveitis, an inflammation of the optic nerve is complicated, there is a significant increase in the concentration of matrix metalloproteinase-9 in the serum, when compared with the control.In patients with uveitis complicated by inflammation of the optic nerve, which for two years has de- veloped partial atrophy of the optic nerve, there was a significantly higher concentration of matrixmetalloproteinazy-9 in the serum in the acute stage of the disease, compared with patients without atrophy of the optic nerve in the long term.Our data indicate that a higher concentration of matrix metalloproteinase-9 in serum correlates with the development of a partial atrophy of the optic nerve due to its inflammation in uveitis.