PATHOGENETIC FEATURES OF DIURNAL VARIATIONS OF HEMODYNAMIC PARAMETERS IN NEUROCIRCULATORY DYSTONIA OF HYPERTONIC TYPE IN NORTHERN RESIDENTS WITH DIFFERENT TYPES OF TEMPERAMENT
The aim of the work was to study the features of hemodynamic rhythms in healthy residents of the northern region and patients with hypertensive neurocirculatory dystonia, depending on the type of temperament. For a comparative analysis of blood pressure regulation disorders and the formation of arterial hypertension, 35 men were examined with a diagnosis of Neurocirculatory dystonia, hypertensive form. To assess the influence of factors of the northern region on the chronophysiological parameters of blood pressure, “conditionally healthy” men living in the city of Khanty-Mansiysk were examined - a comparison group (30 people). The type of temperament (sanguine, phlegmatic, choleric, melancholic) was determined by the method of Eysenck. All subjects under the standard scheme underwent daily monitoring of blood pressure. Measurements were taken every 30 minutes for 2 days. To test the hypothesis of the presence of many cyclicities, a program was used that used wavelet analysis. The following rhythm parameters were analyzed: daily average level of the indicator, periods of constant and insertion rhythms, energy (amplitude) of the rhythm. The p given in the work shows the proportion of cases when the energy of the selected frequency component in the initial series exceeded the corresponding energy in a random permutation. When studying fluctuations in hemodynamic parameters depending on the type of temperament in the northern region in healthy people, elements of climatic desynchronosis are most expressed in people with a melancholic type of temperament. In patients with a hypertensive form of neurocirculatory dystonia, the nosogenic component of desynchronosis joins, which is also most expressed in patients with a weak unbalanced type of temperament (melancholic). In the conditions of the North, there are such types of disturbances in the rhythms of blood pressure as mesoric, hyperamental and ultradian. Taking into account the results of our study when conducting antihypertensive chronotherapy, it is desirable to determine the type of temperament.