Photodynamic therapy in treatment of gynecological diseases
Photodynamic therapy is a technique in which tissue is irradiated with light after the use of a photosensitizing drug that produces singlet oxygen, which has a cytotoxic effect. 60 patients with hyperplasia of endometrial, 72 women with background and precancerous pathology of cervix of the uterus and 6 women of some vulva epithelial diseases were involved into the study. As a photosensitizer there was used «Fotoditazin». In 1,5 - 2 hours red light with the 662 nanometers wavelength was applied for 15-40 minutes, with calculated energy intake 80-300 J/cm<sup>2</sup>. The results of the study show that photodynamic therapy is a promising modality in the treatment of hyperplasia of endometrial, pathology of cervix of the uterus and some vulva epithelial diseases and can be considered to be a method of choice.