Vaccine against hemorrhagic fever with renal syndrome
In «Chumakov Institute of Poliomyelitis and Viral Encephalitides» of the Russian Academy of Medical Sciences there has been developed the first vaccine against hemorrhagic fever with renal syndrome (HFRS) in Russia. «Combo-HFRS-Vac» contains antigens of two hantavirus serotypes: Puumala and Dobrava. «Combo-HFRS-Vac» is a bivalent, univirion, inactivated, concentrated, sorbed vaccine. Vero finite cell line (green monkey kidney cells) serves a substrate for hantavirus accumulation. Laboratory studies methods validation of the vaccine experimental batches has been performed in Federal State Budgetary Institution «Tarasevich State Scientific Research Institute for Standardization and Quality Control of Biologicals».