THE ROLE OF EOTAXIN AND ITS RECEPTOR IN THE MECHANISM OF TUMOR TISSUE EOSINOPHILIA FORMATION IN PATIENTS WITH COLON CANCER
Expression of eotaxin and its receptor CCR3 in tumor tissues of colon cancer patients was investigated. The analysis result of immunohistochemical studies showed that tumors tissue express eotaxin and CCR3 regardless of exist eosinophilic infiltration of tumor. It is shown that the main factor of Tumor-Associated Tissue Eosinophilia in colon cancer is a high level of expression eotaxin receptor tumor tissue.