DEVELOPMENT OF RATIONAL TECHNOLOGY OF CARBON DIOXIDE EXTRACT FROM HERB PORTULACA OLERACEA L.
Currently, one of the urgent problems of the pharmaceutical industry is the creation and implementation of import substituting drugs, including expanding the range of herbal medicines. The development and implementation of import substituting drugs makes it possible to successfully implement the Strategic Plan of the Ministry of Health of the Republic of Kazakhstan for 2017-2021. The aim of the study was the development and production of phytosubstance based on medicinal plant materials Portulaca oleracea L.using rational technology. Material and methods. The object of the study is the dried grass of Portulaca oleracea L., research materials: liquefid carbon dioxide. The technological process was carried out on the basis of Ltd «Drug manufacturing «Zhanafarm». Results and discussion. This article discusses the technology of carbon dioxide extraction, which is one of the modern methods that allow to obtain biological active substances from the primary medicinal raw materials, which is fully consistent with the natural composition. The herb Portulaca oleracea L. in Kazakhstan was not recommended as medicinal plant material in scientific medicine, the chemical composition and medicinal properties of the carbon dioxide extract of Portulaca oleracea L. were not studied. Conclusions. A rational phytosubstance technology has been developed that can replace imported products. As a result of this work, carbon dioxide extract Portulaca oleracea L .is recommended in the pharmaceutical industry as a drug substance.