Mother Extragenital Pathology Influence to Histochemical Indicators of Placental Cells
The placenta provides optimal conditions for fetal development supplying the developing organism by nutrients. Extragenital diseases play an important role among the many factors that lead to dysfunction of the placenta. It was established that maternal liver disease causes morphological transformations in the placenta and changing the physical parameters of the fetus. In this regard we have studied features of histochemical indicators in placental cells of rats with experimental toxic liver damage caused by subcutaneous injection of carbon tetrachloride twice a week for two months. In the cytoplasm of placental cells we determined the content of total proteins, lipids and glycogen, expressed as optical density in conventional units (CU). The findings suggest that the mother’s liver pathology causes a shift of histochemical indicators of placental cells, which manifests itself in the change of the total protein, glycogen and total lipids in giant cells and cells of spongiotrofoblast and trophoblastic beams of labyrinth of hemochorial rat placenta in the experimental group that may delay fetus growth and development.