HCV-related liver cirrhosis: clinical manifestations and causes of adverse outcomes
The article presents the clinical characteristics of 196 patients with HCV-associated liver cirrhosis. It was revealed that cirrhosis is diagnosed in the working age (47,1 years), in 55% of patients decompensation occurs within the first year after diagnosis, 49% of individuals had signs of alcohol addiction. In some cases (2,6%) the hepatocellular carcinoma (HCC) has developed. Surgical treatment of gastroesophageal varices and bleeding prevention with drugs are not widely used. Almost all patients with liver cirrhosis (99%) didn`t receive antiviral therapy of HCV-infection in their past. The causes of death in patients with LC were liver failure or hepatorenal syndrome (64,1%), bleeding from esophageal varices in 25,6%, HCC in 10.3% of cases.