Leukotriene Receptor Antagonists in the Therapy of Bronchial Asthma: for Who, When and How Long
The goal of asthma therapy is to achieve and maintain control, but in real clinical practice about half of patients have an uncontrolled disease. The main drugs for long-term asthma control are inhaled corticosteroids, but there is a significant amount of evidence supporting the concept that some asthma phenotypes seem most sensitive to antileukotriene drugs used as mono or combined with inhaled corticosteroid therapy. Montelukast is the main representative of this class medication. This article discusses practical issues of using montelukast in patients with asthma and/or allergic rhinitis: which patients with asthma will benefit from its appointment, when and how long should the medicaton be used.