THE ANTIPROTEASE ACTIVITY OF FLAVANOIDS
The inhibiting effect of 9 synthetic and 3 plant flavonoids upon proteolytic enzymes - elastase, trypsin and chymotrypsin from pancreas of a pig and collagenase from Clostridium histolyticum were studied in vitro. The values of IC <sub>50</sub> were determined for each flavonoid and proteinase. According to the level of them the degree of inhibiting activity was estimated. The conclusion of the availability of the application of flavonoids, braking the outburst of proteolysis, present at the development of the number of diseases was disscussed.