Cervical neoplasia prediction and clinical risk factors in women with genital papillomavirus infection
Genital papillomavirus infection is highly prevalent in women of reproductive age. However despite its oncogenic properties only a very small number of HPV-infected patients will develop cervical intraepithelial neoplasia or cervical cancer in future. We estimated a clinical value of the new method of cervical neoplasia prediction based on quantifying of the viral integration coeffi cient (E2/ E6 ratio) in HPV-infected women. Clinical risk factors associated with high grades of viral integration have also been evaluated.