Clinical, morphological and microbiological changes and their dynamics of chronic gastroduodenitis in children
An examination of 88 children with chronic gastroduodenitis aged 5-17 years by PCR in gastric juice and/or biopsy of the gastric mucosa and duodenal ulcers in 40% of patients revealed human papilloma viruses a high cancer risk 16, 18 types (HPV), herpes simplex 1, 2 types (HSV), cytomegalovirus (CMV), 14% of them - in isolation and 26% - in association with Helicobacter pylori. Patients with viral persistence was scheduled comprehensive treatment, including antiviral, immunomodulatory, and antibacterial drugs. Through 1.5 months after therapy revealed that in 16 (73%) children viruses are no longer determined. In these patients, significantly more frequently observed the disappearance of abdominal pain syndrome, congestion of the mucous membrane of the stomach and duodenum, decrease the degree of swelling of the latter, as well as the decrease in the depth of inflammation of gastroduodenal mucosa.