USE OF LEFLUNOMIDE IN RHEUMATOID ARTHRITIS: CLINICAL ASPECTS
Leflunomide (LEF; Arava) that has anti-proliferative and anti-inflammatory effects is a disease-modifying antirheumatic drug to treat rheumatoid arthritis (RA). Due to its efficacy and safety, LEF may be used as a first-line agent in patients intolerant to methotrexate and in those with early RA.