Is cardioplegia necessary for coronary artery bypass grafting?
The purpose of the present paper is to analyze the possibility of applying СРВ without cardioplegia during coronary artery bypass grafting (CABG) in patients with low left ventricular ejection fraction.After approval of the Hospital Ethical Committee 21 patients (EF<0.4) aged 43-77 (average 65) undergoing CABG (average 3.3 distal anastomosis) performed by the same team of surgeons were included in the research. Normothermic СРВ without cardioplegia was performed with a-stat management. We used standard haemodynamic monitoring during the procedure. The rates of biomarkers of myocardial injury were evaluated. Postoperative the cardiac output was improved and consequently the index of oxygen delivery got better as well. 18 patients (85.7%) didn't need in inotropic support after surgery. LOS in the ICU 23.6 h, in the hospital - 10.7 days. There wasn't the hospital mortality in the studying group. The myocardial revascularization with СРВ without cardioplegia maintenances hemodynamic in patients with low left ventricular ejection fraction. Level of the high-specific enzymes of myocardial injury and results of ECG prove the effectiveness of these approach.