Efficiency nexium in the complex eradication therapy of patients with peptic ulcer
Purpose of research. To assess the efficiency of esomeprazole (nexium) in the complex for eradication therapy patients with peptic ulcer of the duodenum. Materials and methods. Were examined 30 men with chronic duodenal ulcer associated with Helicobacter pylory without comorbidities. Patients received triple therapy: nexium 20 mg orally 2 times a day during 10 days, then once a day during 14-21 days. With nexiumm in the first 10 days patients received amoxicillin 1000 mg 2 times a day and clarithromycin 500 mg 2 times a day. The treatment efficiency was assessed by dynamics of clinical indicators, findings of endoscopy and the results of eradication therapy. Results. During research we saw a reduction of clinical symptoms of the disease on the second day of treatment, was achieved persistent eradication and no recurrence of ulcers. Conclusions. During treatment with nexium there is a rapid positive dynamics of the regression of clinical symptoms of peptic ulcer of the duodenum. Nexium in combination with amoxicillin and clarithromycin in uncomplicated peptic ulcer disease allowed to achieve the eradication of Helicobacter pylory in 97% of patients.