Gallstone disease: results of our 20-year studies (part 2: the quality of life)
Aim. To estimate the quality of life (QL) of patients with gallstones disease (GSD). Materials and Methods. The quality of life was investigated by means of questionnaires: specific to gallstones disease - “Gallstone Impact Checklist” (GIC), Medical Outcomes Study Short Form (MOS SF-36) and Gastrointestinal Quality of Life Index (GIQLI). Results. QL was significantly worse scale pain in women than men with GSD (18,3±1,5 and 10,8±2,6 points, respectively; p<0,05), as well food and eating scale and total score after cholecystectomy in women (26,0±2,8 и 89,0±9,6 points), than in women with cholecystolithiasis (16,5±2,2 and 61,0±6,8 points, respectively; p<0,05). According to our data QL in women with GSD in combination with metabolic syndrome (MS) is worse on several scales MOS SF-36 compared with women without MS (PF - 44,0±3,8 and 79,0±4,0; RP - 10,8±3,8 and 46,7±9,3; RE - 34,3±2,5 and 46,2±3,1; BP - 32,2±1,9 and 45,7±2 7, GH - 17,6±5,4 and 61,0±8,9, respectively, p<0,05). QL in women with GSD and MS worse on the same scales and VT than women with MS without cholelithiasis (p<0,05). We have shown that QL in chronic pancreatitis patients worse than in acute pancreatitis patients by PF and GH scales MOS SF-36 (PF - 47,2±3,6 and 61,8±3,8; GH - 33,7±2,1 and 43,2±1,8, respectively, p<0,05) and symptom score GIQLI. QL drinkers and smokers patients with different clinical forms of acute and chronic pancreatitis, as well as various indices severity of chronic pancreatitis were worse on certain scales of both questionnaires (MOS SF-36, GIQLI), than non-smokers and non-drinking patients. Conclusions. QL in women with GSD and MS worse than women with MS without cholelithiasis. QL drinkers and smokers patients with acute and chronic pancreatitis were worse on certain scales, than non-smokers and non-drinking patients.