Remodeling of blood vessels in the rat’s brain under the only lipid diet
There are different evaluations about influence of high-lipid diet to different organ and organ systems. Some scientists say that there is big negative influence to cardiovascular system, digestive system, respiratory system, nervous system and kidneys. Other authors say that high-lipid diet prevents diabetes mellitus type 2, metabolic syndrome and obesity. We do our own investigation on white nondescript rats, that ate only water and broadtail fat for a 30 days. Our investigation presents that high-fat diet induces remodeling of rat’s cerebral blood vessels. There appear changes in the structure of blood vessel’s wall and haemodynamic disorders. High-lipid diet may induce activity of Rho-kinase and increase insulin resistance.