PLACE OF CEFIXIME IN THE TREATMENT OF URINARY TRACT INFECTIONS
The article considers the reasons for urinary tract infections (UTI); the principles of rational antibacterial therapy are discussed. It is noted that among the antibacterial agents used for treatment of UTI, III generation cephalosporins, particularly cefixime, have attracted particular attention in terms of efficiency and good tolerability. The results of clinical studies of cefixime are presented. It is emphasized that cefixime can be considered as first-line treatment for most variants of UTI, including acute cystitis and acute pyelonephritis. Particularly, its use is justified in the presence of β-lactamase-producing pathogens. Cefixime can be considered as a treatment of choice in poor tolerance of other treatment options, as well as in groups of patients with highest risk of adverse events (children, elderly patients, pregnant women).