Molecular and genetic characteristics of enteroviruses circulating in ekaterinburg from 2010 to 2012 among clinically healthy children
The article deals with the study of circulation intensity and species composition of non-polio enteroviruses among healthy children in Ekaterinburg in 2010–2012. Eterovirus RNA was detected in 112 of 1 007 (11.1%) samples of faeces using the method of polymerase chain reaction. By the analyzing of nucleotide sequences the authors established the phylogenetic relationships between circulating non-polio enteroviruses and strains isolated from patients with serous meningitis in Sverdlovsk Region in the last 10 years. It was detected that at least six serotypes of non-polio enteroviruses simultaneously circulated in Ekaterinburg in 2010 and 2011; at least eight serotypes circulated in 2012. Among them virus ЕСНО 6 was dominating and related strains that caused outbreaks in Sverdlovsk Region in 2005–2006.