THE RELATIONSHIP BETWEEN SPONDYLARTHRITES AND INFLAMMATORY BOWELS DISEASES
The publications of the last decade reflect the renaissance of the problem of studying the relationships between spondylarthrites and inflammatory bowels diseases. Intestinal inflammation is most often the primary process and precedes spondylarthritis. The main events of the immunopathogenesis are considered to be migration of immune cells from the lymphoid structures of the bowels to the synovial tissue, presentation of arthritogenic structures and activation of immune inflammation in the synovium. A similar spectrum of proinflammatory cytokines is involved in the pathological process. This review presents modern data about the relationships between spondylarthrites and inflammatory bowels diseases. New possibilities of the laboratory examination of patients to prognosticate the development of inflammation in the intestines and the locomotor system, as well as to assess the inflammatory activity are discussed. The possibilities of high-tech treatment of inflammatory bowels diseases and spondylarthrites are analyzed.