The new understanding of the autonomic nervous system role and the nitric oxide generating system in the brain vessels
The article provides a brief history of the study of the autonomic nervous system and the results of many years research of PA. Motavkin and his students, which allowed defining the brain and intramedullary divisions of the autonomic nervous system, referred to it paravasal nerve ganglia and nerve cells, which form functional connections with blood vessels and spinal cord ependymal shell. It is proved that in the brain department of the autonomic nervous system innervates intra-organs blood vessels, paravasal connective tissue, glial and ependymal membrane shell. Intramedullary department within a nervous apparatus of main cerebral vessels is a single unit that can be considered as the departments with a common organization. The concept is analyzed, developed by the authors of the article, according to which the mediators of sym- pathetic nervous system, norepinephrine and epinephrine, which have antioxidant and antiradical properties, protect blood vessels from damage caused by violations of the cycle of nitric oxide and superoxide anion radicals and the formation of highly toxic and reactive nitrogen dioxide.