Immunogenic lipopeptides
Lipoproteins and lipopeptides are amphiphilic compounds. Lipopeptides and their synthetic analogs possess biological activities in vivo, so as immunomodulating, antitumor, antiviral, fungicidal, bactericidal and adjuvant activities. Synthetic lipopeptides (as bacterial analogs) have adjuvant properties, they can cause the production of Th1- and Th2-cytokines, enhance the functional activity of CD8+ T-memory cells and CD4+ T-cell proliferation, which has led to using lipopeptides in the design of vaccine preparations.