NITRIC OXIDE, BLOOD SUPPLY AND WATER BALANCE OF LUNGS IN EXPERIMENTAL ISCHEMIС AND HEMORRHAGIC STROKE
In present work the exploration of nitric oxide, blood supply and water balance of lung in experimental intraventricular hemorrhage and cerebral ischemia was performed. The amount of nitric oxide in bronchoalveolar lavage fluid, venous and arterial blood was estimated by its end metabolites (nitrites and nitrates) content. At the same time the amount of total, extra- and intravascular fluid in lungs and lung blood supply were calculated using the data of wet and dry lung mass, hemoglobin content in blood and lung tissue homogenate. Intraventricular hemorrhage, as well as cerebral ischemia were accompanied by the increase of nitric oxide level in bronchoalveolar lavage fluid and its decrease in arterial and venous blood, with simultaneous augmentation of blood supply and extravascular fluid in lung.