An experimental method of the percutaneous absorbtion of metronidasole in the body with the aid of electrophoresis
The work shows the experimental development of a method of electrophoresis metronidazole. The advantage of this method is the introducing the drug into the body by an electric current transdermally. It reduces the toxic side effects of the drug on other organs and tissues and provides a depot of drug in the formation of pathological focus. As a result, studies have shown thatthe physical and chemical properties of metronidazole resistant to electrical current. The experimental results showed that the electric field metronidazole moves from the anode to the cathode. By ionoforezometria we proved that 8,8% of the formulation goes to penetrate human skin in one session percutaneous electrophoresis for 20 minutes at a current of 15 mA.