What roles do zinc-dependent endopeptidases play in physiological and pathological processes through ECM cleavage?
['["matrix metalloproteinase (MMP)-9", "matrix metalloproteinase-3 (MMP-3) gene ", "matrix metalloproteinases (MMPs)", "Matrix metalloproteinase-9 (MMP-9) is a secreted glycoprotein with a major role in shaping the extracellular matrix and a detailed understanding of the secretory mechanism could help identify methods to correct diseases resulting from dysregulation of secretion.", "Gelatinase B/matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) cleaves many substrates and is produced by most cell types\\u00a0as a zymogen", "Extracellular matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases involved in physiological and pathological processes, through the cleavage of extracellular matrix.", "Extracellular matrix metalloproteinases (MMPs) are a family of endopeptydases which recquire a zinc ion at their active site, for proteolityc activity."]', '["matrix metalloproteinase (MMP)-9", "matrix metalloproteinase-3 (MMP-3) gene ", "matrix metalloproteinases (MMPs)", "Matrix metalloproteinase-9 (MMP-9) is a secreted glycoprotein with a major role in shaping the extracellular matrix and a detailed understanding of the secretory mechanism could help identify methods to correct diseases resulting from dysregulation of secretion.", "Gelatinase B/matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) cleaves many substrates and is produced by most cell types\\u00a0as a zymogen", "Extracellular matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases involved in physiological and pathological processes, through the cleavage of extracellular matrix.", "Extracellular matrix metalloproteinases (MMPs) are a family of endopeptydases which recquire a zinc ion at their active site, for proteolityc activity."]']
Zinc-dependent endopeptidases, specifically extracellular matrix metalloproteinases (MMPs), are involved in physiological and pathological processes through the cleavage of the extracellular matrix. These enzymes play a crucial role in remodeling the ECM and regulating various cellular functions.
[]