Which gene has been implicated in Majeed Syndrome?
['Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome).', 'The gene was mapped to a 5.5 cM interval (1.8 Mb) on chromosome 18p. Examination of genes in this interval led to the identification of homozygous mutations in LPIN2 in affected individuals from the two families. ', 'We conclude that homozygous mutations in LPIN2 result in Majeed syndrome. ', ' genetic alteration of LPIN2 in humans is known to cause Majeed syndrome', 'Majeed syndrome is an autosomal recessive disorder characterised by the triad of chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anaemia and a neutrophilic dermatosis that is caused by mutations in LPIN2', 'ittle is known about the physiological role of lipin-2, the predominant lipin protein present in liver and the deficient gene product in the rare disorder Majeed syndrome.', 'Recent studies have identified mutations that cause lipin-1 or lipin-2 deficiency in humans, leading to acute myoglobinuria in childhood or the inflammatory disorder Majeed syndrome, respectively.', 'An S734L mutation in LPIN2 causes Majeed syndrome', 'Little is known about the physiological role of lipin-2, the predominant lipin protein present in liver and the deficient gene product in the rare disorder Majeed syndrome.', 'A splice site mutation confirms the role of LPIN2 in Majeed syndrome.', 'These data confirm the role of LPIN2 mutations in the etiology of Majeed syndrome.']
['Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome).', 'Genetic alteration of LPIN2 in humans is known to cause Majeed syndrome.']
['LPIN2']