Is Dupilumab used for treatment of atopic dermatitis?
['Dupilumab has demonstrated efficacy in patients with asthma and atopic dermatitis, which are both type 2 helper T-cell-mediated diseases.', 'Background Dupilumab, a human monoclonal antibody against interleukin-4 receptor alpha, inhibits signaling of interleukin-4 and interleukin-13, type 2 cytokines that may be important drivers of atopic or allergic diseases such as atopic dermatitis.', 'Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.', 'Dupilumab is a biologic agent targeted at TH2 cytokines, but indirectly impacts IgE and is an important biologic agent for atopic disease.', 'Dupilumab for the treatment of atopic dermatitis: A clinical trial review.', 'Dupilumab is a novel monoclonal antibody that was recently studied in adult patients with moderate-to-severe AD.', 'Patients treated with dupilumab had marked and rapid improvement in all the evaluated measures of atopic dermatitis disease activity.', 'The robust effects of dupilumab on skin inflammation and pruritus confirm the pathogenic role of IL-4 and IL-13 signaling in adult AD, and further support the application of Th2 cytokine antagonists in the treatment of this disease.']
['Yes, patients treated with dupilumab had marked and rapid improvement in all the evaluated measures of atopic dermatitis disease activity.']
['yes']