Is there any relationship between histone ubiquitylation and splicing?
['histone H2B-specific deubiquitinase and demonstrate that H2B deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.', 'H2B monoubiquitylation (H2BK123ub1) marks introns in Saccharomyces cerevisiae', 'H2B ubiquitination by facilitating splicing', 'pre-mRNA splicing plays a critical role in histone H2B ubiquitination', 'unanticipated functional link between histone H2B ubiquitination and pre-mRNA splicing']
['Yes, in the case of histone H2B']
['yes']