Which is the histone residue methylated by MLL1?
['lack of interaction with the histone methyltransferase, MLL1, resulting in decreased histone H3K4me3 and gene transcription', 'histone H3K4me3 methylase MLL1 complex', 'MEN1 encodes menin, a subunit of MLL1/MLL2-containing histone methyltransferase complexes that trimethylate histone H3 at lysine 4 (H3K4me3', 'MLL1, MLL5, Set1 and ASH1 to be highly up-regulated during transdifferentiation of HSCs. All of these histone methyltransferases regulate methylation of lysine 4 of histone H3, which is a signature of actively transcribed genes', 'MLL1 (Mixed Lineage Leukemia 1), a histone methyltransferase that methylates H3K4 residues', 'H3K4) in Saccharomyces cerevisiae is implemented by Set1/COMPASS, which was originally purified based on the similarity of yeast Set1 to human MLL1 and Drosophila melanogaster Trithorax (Trx)', 'istone H3 lysine 4 (K4) methylation is a prevalent mark associated with transcription activation and is mainly catalyzed by the MLL/SET1 family histone methyltransferase', 'Mutations in the MLL1 SET domain that fail to support overall H3 K4 methylation', 'MLL1, a mammalian homolog of Drosophila trithorax, is an H3K4-specific methyltransferase implicated in transcriptional control', 'We show that the mixed lineage leukemia 1 (MLL1) protein, a histone methyltransferase specific for H3K4', 'MLL1 histone H3 Lys4 methyltransferase complexes', 'MLL1 histone methyltransferase (H3K4me3) complex', 'In the human MLL1 (mixed-lineage leukemia-1) HMT complex, DPY-30L binds to the BRE2 homolog ASH2L in order to regulate histone 3-lysine 4 trimethylation.', 'MLL1 and MLL2 H3K4 methyltransferase complexes are tethered by p52 on the MMP9 but not on the IkappaBalpha promoter, and the H3K4 trimethyltransferase activity r', 'The biological function of MLL1 is mediated by the histone H3K4 methyltransferase activity of the carboxyl-terminal SET domain.', 'Set1/COMPASS is capable of methylating H3K4, a posttranslational modification associated with actively transcribed genes. There is only one Set1 in yeast; yet in mammalian cells there are multiple H3K4 methylases, including Set1A/B, forming human COMPASS complexes, and MLL1-4', ' trimethylated H3K4 histones and histone methyltransferase MLL1', ' lacZ knock-in allele of mixed-lineage leukemia 1 (Mll1), a histone methyltransferase expressed in GABAergic and other cortical neurons, resulted in decreased H3K4 methylation', 'effectors of H3K4 methylation is mixed-lineage leukemia 1 (MLL1)', 'MLL1/MLL2 histone methyltransferase complexes specific for Lys4 of histone H3 (H3K4)', 'H3 K4 methyltransferase MLL1', 'purified complex has a robust MLL1-mediated histone methyltransferase activity that can effect mono-, di-, and trimethylation of H3 K4', "MLL1 localizes with RNA polymerase II (Pol II) to the 5' end of actively transcribed genes, where histone H3 lysine 4 trimethylation occurs"]
['Histone H3 at lysine 4 (H3K4)']
['H3K4']