What is the most probable defect underlying triple negative breast cancer?
['We have previously reported an array comparative genomic hybridization profile that identifies triple-negative breast cancers (TNBC), with BRCA1 dysfunction', 'BRCA1-like status was assessed in 101 patients with early-stage TNBC receiving adjuvant cyclophosphamide-based chemotherapy.', 'Sixty-six tumors (65%) had a BRCA1-like profile.']
['The most probable defect underlying triple negative breast cancer is BRCA1 dysfunction.']
['BRCA1 dysfunction']