Which kinase is regulating stress granule biogenesis?
["5'-AMP-activated protein kinase alpha regulates stress granule biogenesis", 'Multiple lines of evidence link AMPK activity to SG biogenesis. First, pharmacological kinase inhibition interfered with SG formation. Second, AMPK-α knockdown combined with in-depth quantitative SG analysis revealed isoform-specific changes of SG characteristics. Third, overexpression of mutant α-subunits further substantiated that AMPK regulates SG parameters. Finally, we identified the SG-nucleating protein G3BP1 as an AMPK-α2 binding partner. This interaction is stimulated by stress and notably occurs in SGs', 'our data define the master metabolic regulator AMPK as a novel SG constituent that also controls their biogenesis', "5'-AMP-activated protein kinase alpha regulates stress granule biogenesis.", 'Collectively, our data define the master metabolic regulator AMPK as a novel SG constituent that also controls their biogenesis.', 'This interaction is stimulated by stress and notably occurs in SGs. Collectively, our data define the master metabolic regulator AMPK as a novel SG constituent that also controls their biogenesis.', '5&apos;-AMP-activated protein kinase alpha regulates stress granule biogenesis..']
["5'-AMP-activated protein kinase alpha regulates stress granule biogenesis", "Multiple lines of evidence define the master metabolic regulator 5'-AMP-activated protein kinase alpha (AMPK-alpha) as a novel component of stress granules (SGs) that also controls their biogenesis."]
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