Does NADPH oxidase 5 require any subunit for function?
['Nox5 forms a functional oligomer mediated by self-association of its dehydrogenase domain.', ' While Nox1-4 require regulatory subunits, including p22phox, Nox5 activity does not depend on any subunits. ', ' Thus, Nox5 forms a catalytically active oligomer in the membrane that is mediated by its dehydrogenase domain. ', 'Coexpression of specific Nox catalytic subunits (Nox1, Nox2, Nox3, Nox4, or Nox5) along with their corresponding regulatory subunits (NOXO1/NOXA1 for Nox1; p47phox/p67phox/Rac for Nox2; NOXO1 for Nox3; no subunits for Nox4 or Nox5) resulted in marked production of reactive oxygen. ']
['No, NADPH oxidase 5 (NOX5) does not require any subunits for function.']
['no']