Are long non coding RNAs spliced?
['Our analyses indicate that lncRNAs are generated through pathways similar to that of protein-coding genes, with similar histone-modification profiles, splicing signals, and exon/intron lengths.', 'For alternative exons and long noncoding RNAs, splicing tends to occur later, and the latter might remain unspliced in some cases.', 'bosome-mapping data to identify lncRNAs of Caenorhabditis elegans. We found 170 long intervening ncRNAs (lincRNAs), which had single- or multiexonic structures that did not overlap protein-coding transcripts, and about sixty antisense lncRNAs (ancRNAs), which were complementary to protein-coding transcripts', 'We introduce an approach to predict spliced lncRNAs in vertebrate genomes combining comparative genomics and machine learning.', 'Owing to similar alternative splicing pattern to mRNAs, the concept of lncRNA genes was put forward to help systematic understanding of lncRNAs. ', 'Our synthesis of recent studies suggests that neither size, presence of a poly-A tail, splicing, direction of transcription, nor strand specificity are of importance to lncRNA function.']
['Long non coding RNAs appear to be spliced through the same pathway as the mRNAs']
['yes']