Is the regulation of Vsr endonuclease independent of the growth phase of bacteria?
['Growth phase-dependent regulation of Vsr endonuclease', 'Vsr endonuclease levels are growth phase dependent.', 'Growth phase-dependent regulation of Vsr endonuclease may contribute to 5-methylcytosine mutational hot spots in Escherichia coli.', 'Using rabbit polyclonal antibodies, we have shown that the Dcm cytosine methylase of Escherichia coli is maintained at a constant level during cell growth, while Vsr endonuclease levels are growth phase dependent.', 'Vsr endonuclease, which initiates very short patch repair, has been hypothesized to regulate mutation in stationary-phase cells.', 'The efficiency of the two pathways changes during the bacterial life cycle; MMR is more efficient during exponential growth and VSP repair is more efficient during the stationary phase.', 'Overexpression of Vsr does dramatically increase the stationary-phase reversion of a Lac- frameshift allele, but the absence of Vsr has no effect.', 'Using rabbit polyclonal antibodies, we have shown that the Dcm cytosine methylase of Escherichia coli is maintained at a constant level during cell growth, while Vsr endonuclease levels are growth phase dependent', 'The efficiency of the two pathways changes during the bacterial life cycle; MMR is more efficient during exponential growth and VSP repair is more efficient during the stationary phase', 'Vsr endonuclease, which initiates very short patch repair, has been hypothesized to regulate mutation in stationary-phase cells']
['The regulation of Vsr endonuclease levels is growth phase dependent.']
['no']