Which is the main target of the anti-arrhythmic activity of flecainide?
['flecainide (sodium channel blocker) ', 'Flecainide is a sodium channel blocker with minimal effects expected on ventricular repolarization. ', 'Flecainide, a class I antiarrhythmic drug, inhibits Na(+) and RyR2 channels and prevents CPVT.', ' flecainide, a Class I antiarrhythmic drug, improves left ventricular pressure gradient (LVPG) or symptoms in patients with obstructive hypertrophic cardiomyopathy (HCM).', 'Flecainide is a class 1c antiarrhythmic that acts by blocking sodium channels to reduce intracardiac conduction and is used mainly in the treatment of supraventricular arrhythmias. ', 'Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia', 'Flecainide reduces spark and wave frequency in the intact rat cardiomyocyte at therapeutically relevant concentrations but the mechanism involves I(Na) reduction rather than direct ryanodine receptor (RyR2) inhibition.']
['Flecainide is a class 1c antiarrhythmic that acts by blocking sodium channels and is used mainly in the treatment of supraventricular arrhythmias.']
['The sodium channel']