Hy's law measures failure for what organ?
[" Hy's Law of drug-induced hepatocellular jaundice causing a case-fatality rate or need for transplant of 10% or higher has been validated in several large national registries, including the ongoing, prospective U.S. Drug-Induced Liver Injury Network. ", "Enzyme elevations alone may not be harmful, but if caused by a drug and followed by jaundice (called 'Hy's law') there is a high possibility of serious DILI.", "No additional alleles outside those associated with liver injury patterns were found to affect potential severity as measured by Hy's Law criteria.", "We compared its performance with that of Hy's Law, which predicts severity of DILI based on levels of alanine aminotransferase or aspartate aminotransferase and total bilirubin, and validated the model in a separate sample.We conducted a retrospective cohort study of 15,353 Kaiser Permanente Northern California members diagnosed with DILI from 2004 through 2010, liver aminotransferase levels above the upper limit of normal, and no pre-existing liver disease.", "Risk of Acute Liver Failure in Patients With Drug-Induced Liver Injury: Evaluation of Hy's Law and a New Prognostic Model.", "Hy's Law, which states that hepatocellular drug-induced liver injury (DILI) with jaundice indicates a serious reaction, is used widely to determine risk for acute liver failure (ALF).", "Hy's law is a method used to identify drug-induced liver injury (DILI)", "Potential severe liver injury is identified in clinical trials by ALT>3\u2009×\u2009upper limits of normal (ULN) and total bilirubin>2\u2009×\u2009ULN, and termed 'Hy's Law' by the US FDA.", "Severe liver injury is identified by the liver chemistry threshold of alanine aminotransferase (ALT)>3× upper limit of normal (ULN) and bilirubin>2× ULN, termed Hy's law by the Food and Drug Administration. "]
["Hy's law correlates enzyme elevations with liver injury ad subsequent failure."]
['liver']