What is membrane scission?
['To promote membrane scission, dynamin proteins polymerize, wrap around, and constrict the membrane; however, the mechanism underlying their role in membrane fusion remains unclear.', ' Its role in endocytosis may be mediated by its reported interaction with dynamin 2, a 100 kDa GTPase that polymerizes around the necks of budding vesicles and catalyzes membrane scission', "Because the neck's radius is, in general, finite, membrane scission and the consequent pinching off of the vesicle can only occur if it is narrowed to permit the necessary membrane topological reformation.", 'Dynamin recruitment and membrane scission at the neck of a clathrin-coated pit.', 'ESCRT-III is the final complex in the pathway that assembles on endosomes and executes membrane scission of intraluminal vesicles.', 'The scission of biological membranes is facilitated by a variety of protein complexes that bind and manipulate lipid bilayers. ', 'Dynamin-2 is a pleiotropic GTPase whose best-known function is related to membrane scission during vesicle budding from the plasma or Golgi membranes. ', ' Force produced by actin similarly contributes in membrane scission in endocytosis or Golgi remodeling.', 'Dynamin 2 (Dyn2) is a ~100kDa GTPase that assembles around the necks of nascent endocytic and Golgi vesicles and catalyzes membrane scission. ', 'membrane scission protein dynamin-2.', ' Finally, a membrane scission event must occur to release the free virion', ' Furthermore, GTP-dependent membrane scission by dynamin was dramatically elevated by BAR domain proteins. ', 'few can mediate membrane scission to complete the budding process.']
['Membrane scission is the final step in order to complete the budding process, pinching off of the vesicle. To promote membrane scission, dynamin proteins polymerize, wrap around, and constrict the membrane. The scission of biological membranes is facilitated by a variety of protein complexes that bind and manipulate lipid bilayers.']
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