Is depression associated with poor prognosis of brain tumor patients?
['Before surgery 27 patients (35%) had BDI scores indicating the presence of depression. These scores were significantly higher in patients with a history of depression (p = 0.017) and in those with a lower functional outcome (p = 0.015).', 'A lower functional status (KPS score < or = 70) in patients was significantly associated with high depression scores at the 3-month (p = 0.000) and 1-year (p = 0.005) assessments.', 'At all follow-ups, depressed low-grade glioma patients had a significantly shorter survival time, 3.3-5.8 years, compared to non-depressed low-grade glioma patients, 10.0-11.7 years.', 'The results suggest that depression and decreased QOL among low-grade glioma patients is related to shorter survival at long-term follow-up.', 'The adverse impact of depression in relation to survival among cancer patients is currently a subject of great interest in research.', 'In the subgroup of patients with low-grade gliomas, depressive patients had a significantly shorter survival time compared with nondepressive subjects (P = 0.031, Kaplan-Meier survival analysis).', 'Preoperative depression seemed to be a significant prognostic factor for worse survival in low-grade glioma patients.', 'Major depressive disorder was marginally associated with outcomes, while surgical interventions and radiotherapy did not show strong associations with test performances.']
['Yes. In brain tumor patients depression is associated with shorter survival and worse functional outcomes.']
['yes']