Has the protein SETMAR (Metnase) a transposase domain?
['Metnase (SETMAR) is a SET-transposase fusion protein that promotes nonhomologous end joining (NHEJ) repair in humans.', 'The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations.', ' Metnase (also termed SETMAR) is a fusion of a histone methylase and transposase protein that arose specifically in primates. ', 'the only intact Hsmar1 transposase gene exists within a chimeric SET-transposase fusion protein referred to as Metnase or SETMAR. ', 'The Metnase transposase has been remarkably conserved through evolution;', "Metnase (also known as SETMAR) is a SET and transposase fusion protein in humans and plays a positive role in double-strand break (DSB) repair. While the SET domain possesses histone lysine methyltransferase activity, the transposase domain is responsible for 5'-terminal inverted repeat (TIR)-specific binding, DNA looping, and DNA cleavage activities. ", 'Metnase is a fusion gene comprising a SET histone methyl transferase domain and a transposase domain derived from the Mariner transposase.', 'ulated by the DNA repair component Metnase (also termed SETMAR). Metnase contains a SET histone methylase and transposase nuclease domain', 'Metnase is a human SET and transposase domain protein ', 'The human set and transposase domain protein Metnase', ' of transposase-related sequences in humans are pseudogenes. We recently isolated and characterized a SET and transposase domain protein termed Metnase that promotes DNA double-strand break (DSB) repair by non-homologous end-joining (NHEJ). Both the SET and transposase domain were required for its NHEJ activity.', 'Metnase, also known as SETMAR, is a SET and transposase fusion protein with an undefined role in mammalian DNA repair.', 'Biochemical characterization of a SET and transposase fusion protein, Metnase: i', 'Metnase (SETMAR) is a SET and transposase fusion protein that promotes in vivo end joining activity and mediates genomic integration of foreign DNA. ', ' This transposase coding region is part of the SETMAR gene, in which a histone methylatransferase SET domain is fused to an Hsmar1 transposase domain. ', 'The human SETMAR protein preserves most of the activities of the ancestral Hsmar1 transposase.', 'ere we investigate the activity of the human SETMAR protein, a highly expressed fusion between a histone H3 methylase and a mariner family transposase.', 'SETMAR, a new primate chimeric gene resulting from fusion of a SET histone methyltransferase gene to the transposase gene of a mobile element.', 'We identified a protein, termed Metnase, that has a SET domain and a transposase/nuclease domain. ', 'Metnase has a nuclease domain that shares homology with the Transposase family.', 'Metnase (also called SETMAR) is a SET and transposase domain protein that promotes both DNA double-strand break (DSB) repair and restart of stalled replication forks. ']
['Yes, the protein SETMAR (Metnase) has a transposase domain.']
['yes']