请将以下内容总结成两句话，并且需要保留其中的关键技术点和应用效果：Most former ALZ drug candidates have failed in clinical settings, due to an incomplete understanding of the pathogenesis or inefficient routes of administration. However, recent advancements in nanotechnology - specifically the development of lipid nanoparticles (LNPs) - have shown promising results in enhancing drug delivery to the brain, potentially providing a significant improvement in the treatment of Alzheimer's disease.
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此前多数阿尔茨海默病药物候选物在临床试验中因对病程理解不充分或给药途径低效而失败，但最近脂质纳米颗粒（LNPs）在纳米技术领域的进展显著提高了药物向脑部的递送效果，有望大幅改善阿尔茨海默病的治疗。
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