请总结以下对话，使用英文，保留APC、Genes/Gene mutations、T-cell antigen、breakpoints、domains这几项技术名词，并将内容总结到3句话以内。

Amy: Hey John, what's your opinion on the latest research on APCs and T-cell antigens?

John: Well, APCs are crucial in the immune response, especially in presenting T-cell antigens. The breakpoints in their genes or gene mutations can significantly impact their function.

Amy: Totally agree. Also, the domains within these proteins play a key role in antigen recognition and presentation.

John: Exactly, and understanding these domains is vital for future immune therapies.
user
In the conversation, APCs are highlighted as essential for presenting T-cell antigens, with gene mutations and breakpoints significantly affecting their function. The domains within these proteins are crucial for antigen recognition and presentation, which are critical for future immune therapies.
assistant