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The dataset generation failed because of a cast error
Error code: DatasetGenerationCastError
Exception: DatasetGenerationCastError
Message: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 1 new columns ({'InterPro'})
This happened while the json dataset builder was generating data using
hf://datasets/Knlife/SwiwwProtIPG/ipr_go_train.json (at revision a9a97c1992930423cdf29476aebbd552e8968d0e)
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback: Traceback (most recent call last):
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1831, in _prepare_split_single
writer.write_table(table)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/arrow_writer.py", line 644, in write_table
pa_table = table_cast(pa_table, self._schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2272, in table_cast
return cast_table_to_schema(table, schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
raise CastError(
datasets.table.CastError: Couldn't cast
Gene Ontology (molecular function): list<item: struct<GO-ID: string, GO-Name: string>>
child 0, item: struct<GO-ID: string, GO-Name: string>
child 0, GO-ID: string
child 1, GO-Name: string
InterPro: list<item: struct<Beg: int64, End: int64, InterPro-ID: string, InterPro-Name: string, InterPro-Type: string>>
child 0, item: struct<Beg: int64, End: int64, InterPro-ID: string, InterPro-Name: string, InterPro-Type: string>
child 0, Beg: int64
child 1, End: int64
child 2, InterPro-ID: string
child 3, InterPro-Name: string
child 4, InterPro-Type: string
sequence: string
instruction: string
-- schema metadata --
pandas: '{"index_columns": [], "column_indexes": [], "columns": [{"name":' + 625
to
{'Gene Ontology (molecular function)': List({'GO-ID': Value('string'), 'GO-Name': Value('string')}), 'sequence': Value('string'), 'instruction': Value('string')}
because column names don't match
During handling of the above exception, another exception occurred:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1456, in compute_config_parquet_and_info_response
parquet_operations = convert_to_parquet(builder)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1055, in convert_to_parquet
builder.download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 894, in download_and_prepare
self._download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 970, in _download_and_prepare
self._prepare_split(split_generator, **prepare_split_kwargs)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1702, in _prepare_split
for job_id, done, content in self._prepare_split_single(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1833, in _prepare_split_single
raise DatasetGenerationCastError.from_cast_error(
datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 1 new columns ({'InterPro'})
This happened while the json dataset builder was generating data using
hf://datasets/Knlife/SwiwwProtIPG/ipr_go_train.json (at revision a9a97c1992930423cdf29476aebbd552e8968d0e)
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
Gene Ontology (molecular function)
list | sequence
string | instruction
string |
|---|---|---|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0005506",
"GO-Name": " iron ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVLSPADKTNVKTAWGKVGGHAGDYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALSNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHHPADFTPAVHASLDKFLASVSTVLTSKYR
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , iron ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003796",
"GO-Name": "lysozyme activity "
}
] |
MRSLLILVLCFLPLAAPGKVYGRCELAAAMKRMGLDNYRGYSLGNWVCAAKFESNFNTGATNRNTDGSTDYGILQINSRWWCNDGRTPGSKNLCHIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRKHCKGTDVNVWIRGCRL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lysozyme activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003796",
"GO-Name": "lysozyme activity "
}
] |
MRSLLVLVLCFLPLAALGKVYGRCELAAAMKRHGLDKYQGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDVHGMNAWVAWRNRCKGTDVNAWIRGCRL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lysozyme activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0016231",
"GO-Name": "beta-N-acetylglucosaminidase activity "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0003796",
"GO-Name": " lysozyme activity "
}
] |
MRSLLILVLCFLPLAALGKVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the beta-N-acetylglucosaminidase activity , identical protein binding , lysozyme activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005509",
"GO-Name": "calcium ion binding "
},
{
"GO-ID": "GO:0047498",
"GO-Name": " calcium-dependent phospholipase A2 activity "
},
{
"GO-ID": "GO:0005543",
"GO-Name": " phospholipid binding "
},
{
"GO-ID": "GO:0090729",
"GO-Name": " toxin activity "
}
] |
MYPAHLLVLSAVCVSLLGAANIPPHPLNLINFMEMIRYTIPCEKTWGEYTNYGCYCGAGGSGRPIDALDRCCYVHDNCYGDAANIRDCNPKTQSYSYKLTKRTIICYGAAGTCARVVCDCDRTAALCFGDSEYIEGHKNIDTARFCQ
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the calcium ion binding , calcium-dependent phospholipase A2 activity , phospholipid binding , toxin activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005509",
"GO-Name": "calcium ion binding "
},
{
"GO-ID": "GO:0047498",
"GO-Name": " calcium-dependent phospholipase A2 activity "
},
{
"GO-ID": "GO:0005543",
"GO-Name": " phospholipid binding "
},
{
"GO-ID": "GO:0090729",
"GO-Name": " toxin activity "
}
] |
MNPAHLLVLSAVCVSLLGAANIPPHPLNLINFMEMIRYTIPCEKTWGEYADYGCYCGAGGSGRPIDALDRCCYVHDNCYGDAEKKHKCNPKTQSYSYKLTKRTIICYGAAGTCGRIVCDCDRTAALCFGNSEYIEGHKNIDTARFCQ
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the calcium ion binding , calcium-dependent phospholipase A2 activity , phospholipid binding , toxin activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0051537",
"GO-Name": "2 iron, 2 sulfur cluster binding "
},
{
"GO-ID": "GO:0009055",
"GO-Name": " electron transfer activity "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
}
] |
MAATTTTMMGMATTFVPKPQAPPMMAALPSNTGRSLFGLKTGSRGGRMTMAAYKVTLVTPTGNVEFQCPDDVYILDAAEEEGIDLPYSCRAGSCSSCAGKLKTGSLNQDDQSFLDDDQIDEGWVLTCAAYPVSDVTIETHKEEELTA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the 2 iron, 2 sulfur cluster binding , electron transfer activity , metal ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005524",
"GO-Name": "ATP binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0004550",
"GO-Name": " nucleoside diphosphate kinase activity "
},
{
"GO-ID": "GO:0017111",
"GO-Name": " ribonucleoside triphosphate phosphatase activity "
},
{
"GO-ID": "GO:0003723",
"GO-Name": " RNA binding "
}
] |
MAELACFCYPHLENDSYRFIPFNSLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTSDNSRGMNYETSMFNKVAALICEALNSIKVTQSDVASVLSKIVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNAAFTMWKLTYLEHKLMPILDQNFIEYKITLNEDKPISESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNMIEFNLLDQRIIWQNWYAFTSSMKQGNTLEICKKLLFQKMKRESNPFKGLSTDRKMDEVSQIGI
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the ATP binding , metal ion binding , nucleoside diphosphate kinase activity , ribonucleoside triphosphate phosphatase activity , RNA binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005524",
"GO-Name": "ATP binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0004550",
"GO-Name": " nucleoside diphosphate kinase activity "
},
{
"GO-ID": "GO:0017111",
"GO-Name": " ribonucleoside triphosphate phosphatase activity "
},
{
"GO-ID": "GO:0003723",
"GO-Name": " RNA binding "
}
] |
MAELACFCYPHLENDSYKFIPFNNLAIKCMLTAKVDRKDQDKFYNSIIYGIAPPPQFKKRYNTNDNSRGMNYETSMFNKVAVLICEALNSIKVTQSDVANVLSRVVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNAAFTMWKLTYLEHKLMPILDQNFIEYKITVNEDKPISESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNVLEFNLLDQRIIWQNWYAFTSSMKQGNTLDICKKLLFQKMKRESNPFKGLSTDRKMDEVSQIGI
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the ATP binding , metal ion binding , nucleoside diphosphate kinase activity , ribonucleoside triphosphate phosphatase activity , RNA binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0009055",
"GO-Name": "electron transfer activity "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0005506",
"GO-Name": " iron ion binding "
}
] |
MKRMMIVAALAALTTTTVAQAADPAAYVEYRKSVLSATSNYMKAIGITLKEDLAVPNQTADHAKAIASIMETLPAAFPEGTAGIAKTEAKAAIWKDFEAFKVASKKSQDAALELASAAETGDKAAIGAKLQALGGTCKACHKEFKAD
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the electron transfer activity , heme binding , iron ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0042314",
"GO-Name": "bacteriochlorophyll binding "
},
{
"GO-ID": "GO:0045156",
"GO-Name": " electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
}
] |
MADKSDLGYTGLTDEQAQELHSVYMSGLWLFSAVAIVAHLAVYIWRPWF
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the bacteriochlorophyll binding , electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity , metal ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005524",
"GO-Name": "ATP binding "
},
{
"GO-ID": "GO:0004714",
"GO-Name": " transmembrane receptor protein tyrosine kinase activity "
}
] |
DTVTSPDITAIVAVIGAVVLGLTSLTIIILFGFVWHQRWKSRKPASTGQIVLVKEDKELAQLRGMAETVGLANACYAVSTLPSQAEIESLPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIRHSPLCFSYFLGDKESVAPLRIQTAFFQPL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the ATP binding , transmembrane receptor protein tyrosine kinase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008289",
"GO-Name": "lipid binding "
},
{
"GO-ID": "GO:0042834",
"GO-Name": " peptidoglycan binding "
}
] |
MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lipid binding , peptidoglycan binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0009007",
"GO-Name": " site-specific DNA-methyltransferase (adenine-specific) activity "
}
] |
MTEAATQLPISLNILVDSIREAANSTLDETLRSKLGQFMSSSAVSELMANLFESYVGEHEILDAGAGVGSLTAAFVQNATLNGAKSISSTCYEISEVMVYNLIQVLDLCKIRAMEFEVNWQQKIIESDFIQASVEQLLIENYSPKYNKAILNPPYLKIAAKGRERALLQKVGIEASNLYSAFVALAIKQLKSGGELVAITPRSFCNGPYFNDFRKQMLDECSLNKIHVFNSRKSAFKADNVLQENIIYHLTKGETQRKVVTVYSSTCANDINPTIFEVPFDEIVKSNNPDLFIHIVTNEQERELANKAGGLPCSLSDLGIQVSTGKVVDFRTRENLSMEYISNSVPLIFPQHLQRCSIVWPITKAKKPNALIVNEATNNLMVPNGIYVLTRRLTAKEEKRRIVASIYYPDIANVDTVGFDNKINYFHANGKPLDISLAKGLWVFLNSTLIDKYFRQMNGHTQVNATDLRALRYPTREQLEDIANQVDFGEFEQTKIDEIINQSLQLM
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , site-specific DNA-methyltransferase (adenine-specific) activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005539",
"GO-Name": "glycosaminoglycan binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0003796",
"GO-Name": " lysozyme activity "
}
] |
MRSLLILVLCFLPLAALGKVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHATNRNTDGSTDYGILQINSRWWCNDGRTPGSKNLCNIPCSALLSSDITASVNCAKKIASGGNGMNAWVAWRNRCKGTDVHAWIRGCRL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the glycosaminoglycan binding , identical protein binding , lysozyme activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003796",
"GO-Name": "lysozyme activity "
}
] |
MKALLTLVFCLLPLAAQGKVYSRCELAAAMKRLGLDNYRGYSLGNWVCAANYESGFNTQATNRNTDGSTDYGILQINSRWWCDNGKTPRSKNACGIPCSVLLRSDITEAVRCAKRIVSDGDGMNAWVAWRNRCRGTDVSKWIRGCRL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lysozyme activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008289",
"GO-Name": "lipid binding "
},
{
"GO-ID": "GO:0015078",
"GO-Name": " proton transmembrane transporter activity "
}
] |
MASTRVLASRLASQMAASAKVARPAVRVAQVSKRTIQTGSPLQTLKRTQMTSIVNATTRQAFQKRAYSSEIAQAMVEVSKNLGMGSAAIGLTGAGIGIGLVFAALLNGVARNPALRGQLFSYAILGFAFVEAIGLFDLMVALMAKFT
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lipid binding , proton transmembrane transporter activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005185",
"GO-Name": "neurohypophyseal hormone activity "
},
{
"GO-ID": "GO:0031894",
"GO-Name": " V1A vasopressin receptor binding "
}
] |
CYFQNCPRGXXXAMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEEIYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGIGFPRRVXASDRSNATLLDGPSGALLLRLVQLAAAPEPAEPAQPGVY
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the neurohypophyseal hormone activity , V1A vasopressin receptor binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , hemoglobin alpha binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHFTAEEKAAITSTWKLVDVEDAGAEALGRLLVVYPWTQRFFDSFGNLSSSSAIMGNPKVKAHGKKVLTAFGDAVKNVDDLKNTFAHLSELHCDRLHVDPENFKLLGNVLVIVLAKYFGKEFTPQVQSAWQKLVAGVATALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHLTDAEKALVTGLWGKVNADAVGAEALGRLLVVYPWTQRFFEHFGDLSSASAVMNNPQVKAHGKKVIHSFADGLKHLDNLKGAFSSLSELHCDKLHVDPENFKLLGNMIIIVLSHDLGKDFTPSAQSAFHKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0031722",
"GO-Name": " hemoglobin beta binding "
},
{
"GO-ID": "GO:0030492",
"GO-Name": " hemoglobin binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
}
] |
MVHLTDAEKAAVNGLWGKVNPDDVGGEALGRLLVVYPWTQRYFDSFGDLSSASAIMGNPKVKAHGKKVINAFNDGLKHLDNLKGTFAHLSELHCDKLHVDPENFRLLGNMIVIVLGHHLGKEFTPCAQAAFQKVVAGVASALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , hemoglobin alpha binding , hemoglobin beta binding , hemoglobin binding , metal ion binding , oxygen binding , oxygen carrier activity , protein-containing complex binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MVHLTDAEKSAVSCLWAKVNPDEVGGEALGRLLVVYPWTQRYFDSFGDLSSASAIMGNPKVKAHGKKVITAFNEGLKNLDNLKGTFASLSELHCDKLHVDPENFRLLGNAIVIVLGHHLGKDFTPAAQAAFQKVVAGVATALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MVHLTDAEKAAVSCLWGKVNSDEVGGEALGRLLVVYPWTQRYFDSFGDLSSASAIMGNAKVKAHGKKVITAFNDGLNHLDSLKGTFASLSELHCDKLHVDPENFRLLGNMIVIVLGHHLGKDFTPAAQAAFQKVVAGVATALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0001540",
"GO-Name": "amyloid-beta binding "
},
{
"GO-ID": "GO:0016209",
"GO-Name": " antioxidant activity "
},
{
"GO-ID": "GO:0120020",
"GO-Name": " cholesterol transfer activity "
},
{
"GO-ID": "GO:0019899",
"GO-Name": " enzyme binding "
},
{
"GO-ID": "GO:0043395",
"GO-Name": " heparan sulfate proteoglycan binding "
},
{
"GO-ID": "GO:0008201",
"GO-Name": " heparin binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0008289",
"GO-Name": " lipid binding "
},
{
"GO-ID": "GO:0005319",
"GO-Name": " lipid transporter activity "
},
{
"GO-ID": "GO:0071813",
"GO-Name": " lipoprotein particle binding "
},
{
"GO-ID": "GO:0050750",
"GO-Name": " low-density lipoprotein particle receptor binding "
},
{
"GO-ID": "GO:0046911",
"GO-Name": " metal chelating activity "
},
{
"GO-ID": "GO:0060228",
"GO-Name": " phosphatidylcholine-sterol O-acyltransferase activator activity "
},
{
"GO-ID": "GO:0005543",
"GO-Name": " phospholipid binding "
},
{
"GO-ID": "GO:0046983",
"GO-Name": " protein dimerization activity "
},
{
"GO-ID": "GO:0042803",
"GO-Name": " protein homodimerization activity "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
},
{
"GO-ID": "GO:0048018",
"GO-Name": " receptor ligand activity "
},
{
"GO-ID": "GO:0005102",
"GO-Name": " signaling receptor binding "
},
{
"GO-ID": "GO:0005198",
"GO-Name": " structural molecule activity "
},
{
"GO-ID": "GO:0048156",
"GO-Name": " tau protein binding "
},
{
"GO-ID": "GO:0070326",
"GO-Name": " very-low-density lipoprotein particle receptor binding "
}
] |
MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the amyloid-beta binding , antioxidant activity , cholesterol transfer activity , enzyme binding , heparan sulfate proteoglycan binding , heparin binding , identical protein binding , lipid binding , lipid transporter activity , lipoprotein particle binding , low-density lipoprotein particle receptor binding , metal chelating activity , phosphatidylcholine-sterol O-acyltransferase activator activity , phospholipid binding , protein dimerization activity , protein homodimerization activity , protein-containing complex binding , receptor ligand activity , signaling receptor binding , structural molecule activity , tau protein binding , very-low-density lipoprotein particle receptor binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008289",
"GO-Name": "lipid binding "
},
{
"GO-ID": "GO:0042834",
"GO-Name": " peptidoglycan binding "
}
] |
MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lipid binding , peptidoglycan binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVNLTSDEKTAVLALWNKVDVEDCGGEALGRLLVVYPWTQRFFESFGDLSTPAAVFANAKVKAHGKKVLTSFGEGMNHLDNLKGTFAKLSELHCDKLHVDPENFKLLGNMLVVVLARHFGKEFDWHMHACFQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHLSSEEKSAVTALWGKVNVEEVGGEALGRLLVVYPWTQRFFESFGDLSSANAVMNNPKVKAHGKKVLAAFSEGLSHLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVIVLSHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MTLLSAEENAHVTSLWGKVDVEKVGGEALGRLLVVYPWTQRFFESFGDLSSPSAVMGNPKVKAHGKKVLSAFSEGLHHLDNLKGTFAQLSELHCDKLHVDPQNFTLLGNVLVVVLAEHFGNAFSPAVQAAFQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHLTPEEKAAVAALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPAAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPQVQAAFQKVVAGVATALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , hemoglobin alpha binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHLTGDEKAAVTALWGKVNVEDVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMNNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MVHLSAEEKEAVLGLWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSNADAVMGNPKVKAHGKKVLQSFSDGLKHLDNLKGTFAKLSELHCDQLHVDPENFRLLGNVIVVVLARRLGHDFNPNVQAAFQKVVAGVANALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , hemoglobin alpha binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MVHFTAEEKSVITGLWGKVNVEETGGQAVGRLLVVYPWTQRFFDSFGNMSSPSAIMGNPKVKAHGKKVLTAFGDAVKNMDNLKGTFAKLSELHCDKLHVDPENFRLLGNMIVIILASHFGGEFTPEVQAAWQKLVAGVATALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , hemoglobin alpha binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008289",
"GO-Name": "lipid binding "
},
{
"GO-ID": "GO:0042834",
"GO-Name": " peptidoglycan binding "
}
] |
MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lipid binding , peptidoglycan binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0004556",
"GO-Name": "alpha-amylase activity "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
}
] |
MFAKRFKTSLLPLFAGFLLLFHLVLAGPAAASAETANKSNELTAPSIKSGTILHAWNWSFNTLKHNMKDIHDAGYTAIQTSPINQVKEGNQGDKSMSNWYWLYQPTSYQIGNRYLGTEQEFKEMCAAAEEYGIKVIVDAVINHTTSDYAAISNEVKSIPNWTHGNTQIKNWSDRWDVTQNSLLGLYDWNTQNTQVQSYLKRFLDRALNDGADGFRFDAAKHIELPDDGSYGSQFWPNITNTSAEFQYGEILQDSASRDAAYANYMDVTASNYGHSIRSALKNRNLGVSNISHYASDVSADKLVTWVESHDTYANDDEESTWMSDDDIRLGWAVIASRSGSTPLFFSRPEGGGNGVRFPGKSQIGDRGSALFEDQAITAVNRFHNVMAGQPEELSNPNGNNQIFMNQRGSHGVVLANAGSSSVSINTATKLPDGRYDNKAGAGSFQVNDGKLTGTINARSVAVLYPDDIAKAPHVFLENYKTGVTHSFNDQLTITLRADANTTKAVYQINNGPETAFKDGDQFTIGKGDPFGKTYTIMLKGTNSDGVTRTEKYSFVKRDPASAKTIGYQNPNHWSQVNAYIYKHDGSRVIELTGSWPGKPMTKNADGIYTLTLPADTDTTNAKVIFNNGSAQVPGQNQPGFDYVLNGLYNDSGLSGSLPH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the alpha-amylase activity , metal ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005179",
"GO-Name": "hormone activity "
}
] |
AANPHLCGSHLVEALYLVCGERGFFYQPKGIHZZCCHKPCBIFZLZBYCN
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the hormone activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0015459",
"GO-Name": "potassium channel regulator activity "
},
{
"GO-ID": "GO:0090729",
"GO-Name": " toxin activity "
}
] |
MISMLRCTFFFLSVILITSYFVTPTMSIKCNCKRHVIKPHICRKICGKNG
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the potassium channel regulator activity , toxin activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0042802",
"GO-Name": "identical protein binding "
},
{
"GO-ID": "GO:0003723",
"GO-Name": " RNA binding "
}
] |
MSKTIVLSVGEATRTLTEIQSTADRQIFEEKVGPLVGRLRLTASLRQNGAKTAYRVNLKLDQADVVDCSTSVCGELPKVRYTQVWSHDVTIVANSTEASRKSLYDLTKSLVATSQVEDLVVNLVPLGR
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the identical protein binding , RNA binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008009",
"GO-Name": "chemokine activity "
},
{
"GO-ID": "GO:0045236",
"GO-Name": " CXCR chemokine receptor binding "
},
{
"GO-ID": "GO:0055056",
"GO-Name": " D-glucose transmembrane transporter activity "
},
{
"GO-ID": "GO:0008083",
"GO-Name": " growth factor activity "
}
] |
MSLRLDTTPSCNSARPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the chemokine activity , CXCR chemokine receptor binding , D-glucose transmembrane transporter activity , growth factor activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0046982",
"GO-Name": " protein heterodimerization activity "
},
{
"GO-ID": "GO:0030527",
"GO-Name": " structural constituent of chromatin "
}
] |
MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , protein heterodimerization activity , structural constituent of chromatin required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0046982",
"GO-Name": " protein heterodimerization activity "
},
{
"GO-ID": "GO:0030527",
"GO-Name": " structural constituent of chromatin "
}
] |
MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAVKAK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , protein heterodimerization activity , structural constituent of chromatin required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0051015",
"GO-Name": "actin filament binding "
},
{
"GO-ID": "GO:0005524",
"GO-Name": " ATP binding "
},
{
"GO-ID": "GO:0030899",
"GO-Name": " calcium-dependent ATPase activity "
},
{
"GO-ID": "GO:0005516",
"GO-Name": " calmodulin binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0000146",
"GO-Name": " microfilament motor activity "
},
{
"GO-ID": "GO:0019901",
"GO-Name": " protein kinase binding "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
}
] |
MTDAQMADFGAARYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKDNPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSGKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKMVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSHMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIWQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDDLKENIAIVERRNTLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the actin filament binding , ATP binding , calcium-dependent ATPase activity , calmodulin binding , identical protein binding , microfilament motor activity , protein kinase binding , protein-containing complex binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0051015",
"GO-Name": "actin filament binding "
},
{
"GO-ID": "GO:0005524",
"GO-Name": " ATP binding "
},
{
"GO-ID": "GO:0000146",
"GO-Name": " microfilament motor activity "
},
{
"GO-ID": "GO:0008307",
"GO-Name": " structural constituent of muscle "
}
] |
MSLEHEKDPGWQYLKRSREQQLADQSRPYDSKKNVWIPDAEEGYIEGVIKGPGPKADTVIVTAGGKDVTLKKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAMLIYTYSGLFCVVINPYKRLPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKKVICYFATVGASQKAALKEGEKEVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFNKHGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLRDELLLNHPISNYWFVAQAELLIDGIDDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMHMGNMKFKQRPREEQAEPDGQDEAERACNMYGIDVDQFLKALVSPRVKVGTEWVSKGQNVDQVHWAIGAMAKGLYARVFHWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEECIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNVLNWLEKNKDPLNDTVVSVMKASKKNDLLVEIWQDYTTQEEAAAAAKAGGGRKGGKSGSFMTVSMMYRESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFPNRTQHPDFVQRYAILAAKEAKSSDDMKTCAGAILQALINQKQLNDEQFRIGHTKVFFKAGVVAHIEDLRDDKLNQIITGFQSAIRWYTATADAGARRKQLNSYIILQRNIRSWCVLRTWDWFLLFGKLRPQLKCGKMAEEMIKMAEEQKVLEAEAKKAESARKSQEEAYAKLSAERSKLLEALELTQGGSAAIEEKLTRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVENLKKSIEAVDGNLAKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVDDLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDELSAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQRELDELNERLDEQNKQLEIQQDNNKKKDSEIIKFRRDLDEKNMANEDQMAMIRRKNNDQISALTNTLDALQKSKAKIEKEKGVLQKELDDINAQVDQETKSRVEQERLAKQYEIQVAELQQKVDEQSRQIGEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAAEDELHERQEFHAACKNLEHELDQCHELLEEQINGKDDIQRQLSRINSEISQWKARYEGEGLVGSEELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLAETEDARSDVDRHLTVIASLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSEQIETLRRENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAALEAEESKVLRLQIEVQQIRSEIEKRIQEKEEEFENTRKNHQRALESIQASLETEAKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRRREEIRENYLAAEKRLAIALSESEDLAHRIEASDKHKKQLEIEQAELKSSNTELIGNNAALSAMKRKVENEVQIARNELDEYLNELKASEERARKAAADADRLAEEVRQEQEHAVHVDRQRKSLELNAKELQAKIDDAERAMIQFGAKALAKVEDRVRSLEAELHSEQRRHQESIKGYTKQERRARELQFQVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAEEVATQNLSKFRQIQLALENAEERAEVAENSLVRMRGQVVRSATNK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the actin filament binding , ATP binding , microfilament motor activity , structural constituent of muscle required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031716",
"GO-Name": "calcitonin receptor binding "
},
{
"GO-ID": "GO:0005179",
"GO-Name": " hormone activity "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0005184",
"GO-Name": " neuropeptide hormone activity "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
},
{
"GO-ID": "GO:0005102",
"GO-Name": " signaling receptor binding "
}
] |
MGFLKFSPFLVVSILLLYQACGLQAVPLRSTLESSPGMAATLSEEEARLLLAALVQNYMQMKVRELEQEQEAEGSSVTAQKRSCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAFGRRRRDLQA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the calcitonin receptor binding , hormone activity , identical protein binding , neuropeptide hormone activity , protein-containing complex binding , signaling receptor binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0016829",
"GO-Name": "lyase activity "
},
{
"GO-ID": "GO:0003676",
"GO-Name": " nucleic acid binding "
},
{
"GO-ID": "GO:0004522",
"GO-Name": " ribonuclease A activity "
}
] |
KETAAMKFQRQHMDSGSSLSSSSDYCNKMMKVRNMTQESCKPVNTFVHESLQDVQAVCFQENVTCKNGQQNCHQSRSNMHITDCRQTSGSKYPNCLYQTSNMNRHIIIACEGNPYVPVHFDASVEDST
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the lyase activity , nucleic acid binding , ribonuclease A activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0051015",
"GO-Name": "actin filament binding "
},
{
"GO-ID": "GO:0005524",
"GO-Name": " ATP binding "
},
{
"GO-ID": "GO:0016887",
"GO-Name": " ATP hydrolysis activity "
},
{
"GO-ID": "GO:0005516",
"GO-Name": " calmodulin binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0000146",
"GO-Name": " microfilament motor activity "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
}
] |
MADREMAAFGAGAPFLRKSEKERLEAQTRPFDLKKDVFVPDDKEEFVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAQVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQTPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFFSQGETTVASIDDSEEHMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLKLLSNLFANYAGADAPVDKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLDQDKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTRQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILVEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKNNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKGLNEE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the actin filament binding , ATP binding , ATP hydrolysis activity , calmodulin binding , identical protein binding , microfilament motor activity , protein-containing complex binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005179",
"GO-Name": "hormone activity "
}
] |
MAPPQHLCGSHLVDALYLVCGDRGFFYNSGIVEQCCHRPCDKFDLQSYCN
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the hormone activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005179",
"GO-Name": "hormone activity "
}
] |
YVGQRLCGSQLVDTLYSVCKHRGFYRPSEGIVDQCCTNICSRNQLLTYCN
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the hormone activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0009055",
"GO-Name": "electron transfer activity "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0005506",
"GO-Name": " iron ion binding "
}
] |
MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYHQKYR
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the electron transfer activity , heme binding , iron ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0051538",
"GO-Name": "3 iron, 4 sulfur cluster binding "
},
{
"GO-ID": "GO:0051539",
"GO-Name": " 4 iron, 4 sulfur cluster binding "
},
{
"GO-ID": "GO:0009055",
"GO-Name": " electron transfer activity "
},
{
"GO-ID": "GO:0016491",
"GO-Name": " oxidoreductase activity "
},
{
"GO-ID": "GO:0008270",
"GO-Name": " zinc ion binding "
}
] |
GIDPNYRTSKPVVGDHSGHKIYGPVESPKVLGVHGTIVGVDFDLCIADGSCITACPVNVFQWYETPGHPASEKKADPVNEQACIFCMACVNVCPVAAIDVKPP
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the 3 iron, 4 sulfur cluster binding , 4 iron, 4 sulfur cluster binding , electron transfer activity , oxidoreductase activity , zinc ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003998",
"GO-Name": "acylphosphatase activity "
}
] |
MSALTKASGALKSVDYEVFGRVQGVCFRMYTEEEARKLGVVGWVKNTRQGTVTGQVQGPEDKVNAMKSWLSKVGSPSSRIDRTNFSNEKEISKLDFSGFSTRY
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the acylphosphatase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0004869",
"GO-Name": "cysteine-type endopeptidase inhibitor activity "
},
{
"GO-ID": "GO:0002020",
"GO-Name": " protease binding "
}
] |
MDPGTTGIVGGVSEAKPATPEIQEVADKVKRQLEEKTNEKYEKFKVVEYKSQVVAGQILFMKVDVGNGRFLHMKVLRGLSGDDDLKLLDYQTNKTKNDELTDF
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the cysteine-type endopeptidase inhibitor activity , protease binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0046982",
"GO-Name": " protein heterodimerization activity "
},
{
"GO-ID": "GO:0030527",
"GO-Name": " structural constituent of chromatin "
}
] |
MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , identical protein binding , protein heterodimerization activity , structural constituent of chromatin required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0042802",
"GO-Name": "identical protein binding "
},
{
"GO-ID": "GO:0008289",
"GO-Name": " lipid binding "
},
{
"GO-ID": "GO:0042834",
"GO-Name": " peptidoglycan binding "
}
] |
MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the identical protein binding , lipid binding , peptidoglycan binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0046982",
"GO-Name": " protein heterodimerization activity "
},
{
"GO-ID": "GO:0030527",
"GO-Name": " structural constituent of chromatin "
}
] |
MAGGKGGKGMGKVGAKRHSKRSNKASIEGITKPAIRRLARRGGVKRISSFIYDDSRQVLKSFLENVVRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , protein heterodimerization activity , structural constituent of chromatin required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003729",
"GO-Name": "mRNA binding "
},
{
"GO-ID": "GO:0003723",
"GO-Name": " RNA binding "
},
{
"GO-ID": "GO:0003727",
"GO-Name": " single-stranded RNA binding "
},
{
"GO-ID": "GO:0003735",
"GO-Name": " structural constituent of ribosome "
}
] |
MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the mRNA binding , RNA binding , single-stranded RNA binding , structural constituent of ribosome required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003729",
"GO-Name": "mRNA binding "
},
{
"GO-ID": "GO:0003735",
"GO-Name": " structural constituent of ribosome "
}
] |
MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the mRNA binding , structural constituent of ribosome required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003729",
"GO-Name": "mRNA binding "
},
{
"GO-ID": "GO:0003735",
"GO-Name": " structural constituent of ribosome "
}
] |
MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the mRNA binding , structural constituent of ribosome required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003729",
"GO-Name": "mRNA binding "
},
{
"GO-ID": "GO:0003735",
"GO-Name": " structural constituent of ribosome "
}
] |
MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the mRNA binding , structural constituent of ribosome required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0009055",
"GO-Name": "electron transfer activity "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0005506",
"GO-Name": " iron ion binding "
}
] |
MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVVEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNSYHKKYR
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the electron transfer activity , heme binding , iron ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0004308",
"GO-Name": "exo-alpha-sialidase activity "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
}
] |
MNPNQKIICISATGMTLSVVSQLIGLANLGLNIGLHFKVGETPEIGTPSVNETNSTTTIINYNTQNNFTNVTNIVLIKEEDEMFTNLSKPLCEVNSWHILSRT
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the exo-alpha-sialidase activity , metal ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005524",
"GO-Name": "ATP binding "
},
{
"GO-ID": "GO:0046933",
"GO-Name": " proton-transporting ATP synthase activity, rotational mechanism "
}
] |
MVTIRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLLIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISASEFRLIESAAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTTLQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYLGDVFYLHSRLLERAAKLSSSLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNSGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLTVEEQIMTIYTGTNGYLDSLEVGQVRKFLVELRTYLKTNKPQFQEIISSTKTFTEEAEALLKEAIQEQMDRFILQEQA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the ATP binding , proton-transporting ATP synthase activity, rotational mechanism required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHFTAEEKAAITGLWGKVNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSFGEAIKNLDNLKGAFAKLSELHCDKLHVDPENFRLLGNVIVIILATHFGREFTPDVQAAWQKLVSGVATALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0031721",
"GO-Name": " hemoglobin alpha binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
MVHFTPEEKCIISKQWGQVNIDETGGEALGRLLVVYPWTQRFFDNFGNLSSSSAIMGNPKVKAHGKKVLTSFGDAIKNMDNLKGAFAKLSELHCDKLHVDPENFKLLGNVLLIVLATHFGKEFTPEVQAAWQKLVSGVAIALAHKYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , hemoglobin alpha binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0000287",
"GO-Name": "magnesium ion binding "
},
{
"GO-ID": "GO:0004497",
"GO-Name": " monooxygenase activity "
},
{
"GO-ID": "GO:0016984",
"GO-Name": " ribulose-bisphosphate carboxylase activity "
}
] |
MPKTQSAAGYKAGVKDYKLTYYTPDYTPKDTDLLAAFRFSPQPGVPADEAGAAIAAESSTGTWTTVWTDLLTDMDRYKGKCYHIEPVQGEENSYFAFIAYPLDLFEEGSVTNILTSIVGNVFGFKAIRSLRLEDIRFPVALVKTFQGPPHGIQVERDLLNKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKSQAETGEIKGHYLNVTAPTCEEMMKRAEFAKELGMPIIMHDFLTAGFTANTTLAKWCRDNGVLLHIHRAMHAVIDRQRNHGIHFRVLAKCLRLSGGDHLHSGTVVGKLEGDKASTLGFVDLMREDHIEADRSRGVFFTQDWASMPGVLPVASGGIHVWHMPALVEIFGDDSVLQFGGGTLGHPWGNAPGATANRVALEACVQARNEGRDLYREGGDILREAGKWSPELAAALDLWKEIKFEFETMDKL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the magnesium ion binding , monooxygenase activity , ribulose-bisphosphate carboxylase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003735",
"GO-Name": "structural constituent of ribosome "
},
{
"GO-ID": "GO:0008270",
"GO-Name": " zinc ion binding "
}
] |
MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the structural constituent of ribosome , zinc ion binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003735",
"GO-Name": "structural constituent of ribosome "
}
] |
MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the structural constituent of ribosome required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003735",
"GO-Name": "structural constituent of ribosome "
}
] |
MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the structural constituent of ribosome required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0019899",
"GO-Name": "enzyme binding "
},
{
"GO-ID": "GO:0034235",
"GO-Name": " GPI anchor binding "
},
{
"GO-ID": "GO:0005096",
"GO-Name": " GTPase activator activity "
},
{
"GO-ID": "GO:0005178",
"GO-Name": " integrin binding "
},
{
"GO-ID": "GO:0019901",
"GO-Name": " protein kinase binding "
}
] |
MNPVISITLLLSVLQMSRGQRVISLTACLVNQNLRLDCRHENNTNLPIQHEFSLTREKKKHVLSGTLGVPEHTYRSRVNLFSDRFIKVLTLANFTTKDEGDYMCELRVSGQNPTSSNKTINVIRDKLVKCGGISLLVQNTSWLLLLLLSLSFLQATDFISL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the enzyme binding , GPI anchor binding , GTPase activator activity , integrin binding , protein kinase binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MKFFIVLALCIVGAIADPVSSDQANAIRASWAGVKHNEVDILAAVFSDHPDIQARFPQFAGKDLASIKDTGAFATHAGRIVGFISEIVALVGNESNAPAMATLINELSTSHHNRGITKGQFNEFRSSLVSYLSSHASWNDATADAWTHGLDNIFGMIFAHL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
MKFFAVLALCIVGAIASPLSADQAALVKSTWAQVRNSEVEILAAVFTAYPDIQARFPQFAGKDVASIKDTGAFATHAGRIVGFVSEIIALIGNESNAPAVQTLVGQLAASHKARGISQAQFNEFRAGLVSYVSSNVAWNAAAESAWTAGLDNIFGLLFAAL
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0046872",
"GO-Name": "metal ion binding "
},
{
"GO-ID": "GO:0005212",
"GO-Name": " structural constituent of eye lens "
},
{
"GO-ID": "GO:0051082",
"GO-Name": " unfolded protein binding "
}
] |
MDVTIQHPWFKRALGPFYHNRLFDQFFGEGLFEYDLLPFQSLFRTVLDSGISEVRSDRDQFLILLDHFSPEDLTVKVLDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDKSALSCSLSADGMLTFCGPKVQSGMDASHSERAIPVSREEKASSAPNS
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the metal ion binding , structural constituent of eye lens , unfolded protein binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005525",
"GO-Name": "GTP binding "
},
{
"GO-ID": "GO:0016787",
"GO-Name": " hydrolase activity "
},
{
"GO-ID": "GO:0005200",
"GO-Name": " structural constituent of cytoskeleton "
}
] |
ITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEGEAEEEGEEY
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the GTP binding , hydrolase activity , structural constituent of cytoskeleton required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003684",
"GO-Name": "damaged DNA binding "
},
{
"GO-ID": "GO:0003904",
"GO-Name": " deoxyribodipyrimidine photo-lyase activity "
},
{
"GO-ID": "GO:0003677",
"GO-Name": " DNA binding "
},
{
"GO-ID": "GO:0071949",
"GO-Name": " FAD binding "
}
] |
MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLKRLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNELIWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQPIVEHKEARVQTLAAYEAARKGK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the damaged DNA binding , deoxyribodipyrimidine photo-lyase activity , DNA binding , FAD binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:1990254",
"GO-Name": "keratin filament binding "
},
{
"GO-ID": "GO:0005200",
"GO-Name": " structural constituent of cytoskeleton "
}
] |
MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGACGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRTKN
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the keratin filament binding , structural constituent of cytoskeleton required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0004519",
"GO-Name": "endonuclease activity "
}
] |
MIKWTMINIYLLLMFLIIKNNNNNNNYNNITKYNKDMDLYSIQSPYIKNMNIIKRGYHTSLNNKLIIVQKDNKNNNKNNLEMDNFYKWLVGFTDGDGSFYIKLNDKKYLRFFYGFRMHIDDKACLEKIRNMLNMPSNFEETTKTIMLVNSQKKWLYSNIVTIFDKYPCLTIKYYSYYKWKMAMINNLNGMSYNNKDLLNIKNTINNYEVMPNLKIPYDKMNDYWILGFIEAEGSFDTSPKRNICGFNVSQHKRSINTLKAIKSYVLNNWKPIDNTPLLIKNKLLKDWDSSIKLTKPDKNGVIKLEFNRMDFLYYVILPKLYSLKWYSRKEIDFQLWKTTMEIYMKGLHNTTKGSNLLKLINNNINKKRYYSNYNISKNIIDDVLNMNTIYNYKLPYRMNSDIQRLNSMNNNNTKFINVGVFVYDLNNTLIMTFTGYRPAATYFNCSKHEIAKYIKNGNVFMNKYILKNILLD
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the endonuclease activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0020037",
"GO-Name": "heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
}
] |
GLSAAQRQVIAATWKDIAGADNGAGVGKDCLIKFLSAHPQMAAVFGFSGASDPGVAALGAKVLAQIGVAVSHLGDEGKMVAQMKAVGVRHKGYGNKHIKAQYFEPLGASLLSAMEHRIGGKMNAAAKDAWAAAYADISGALISGLQS
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the heme binding , metal ion binding , oxygen binding , oxygen carrier activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0005198",
"GO-Name": " structural molecule activity "
}
] |
MRHKRSAKRTKRASATQLYKTCKQAGTCPPDIIPKVEGKTIAEQILQYGSMGVFFGGLGIGTGSGTGGRTGYIPLGTRPPTATDTLAPVRPPLTVDPVGPSDPSIVSLVEETSFIDAGAPTSVPSIPPDVSGFSITTSTDTTPAILDINNTVTTVTTHNNPTFTDPSVLQPPTPAETGGHFTLSSSTISTHNYEEIPMDTFIVSTNPNTVTSSTPIPGSRPVARLGLYSRTTQQVKVVDPAFVTTPTKLITYDNPAYEGIDVDNTLYFSSNDNSINIAPDPDFLDIVALHRPALTSRRTGIRYSRIGNKQTLRTRSGKSIGAKVHYYYDLSTIDPAEEIELQTITPSTYTTTSHAASPTSINNGLYDIYADDFITDTSTTPVPSVPSTSLSGYIPANTTIPFGGAYNIPLVSGPDIPINITDQAPSLIPIVPGSPQYTIIADAGDFYLHPSYYMLRKRRKRLPYFFSDVSLAA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , structural molecule activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0015487",
"GO-Name": "melibiose:monoatomic cation symporter activity "
},
{
"GO-ID": "GO:0043887",
"GO-Name": " melibiose:sodium symporter activity "
},
{
"GO-ID": "GO:0015592",
"GO-Name": " methylgalactoside transmembrane transporter activity "
}
] |
MSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEGTTQIVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTAGVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHLTLKAIVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAGAANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMSYHNVVLIVIAGILLNVGTALFWVLQVIMVADIVDYGEYKLHVRCESIAYSVQTMVVKGGSAFAAFFIAVVLGMIGYVPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDKYRKVPPEPVHADIPVGAVSDVKA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the melibiose:monoatomic cation symporter activity , melibiose:sodium symporter activity , methylgalactoside transmembrane transporter activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0004129",
"GO-Name": "cytochrome-c oxidase activity "
},
{
"GO-ID": "GO:0004519",
"GO-Name": " endonuclease activity "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
}
] |
MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGQTVATIIMLMMYNDMHFSKCWKLLKKWITNIMSTLFKALFVKMFMSYNNQQDKMMNNTMLKKDNIKRSSETTRKMLNNSMNKKFNQWLAGLIDGDGYFGIVSKKYVSLEITVALEDEMALKEIQNKFGGSIKLRSGVKAIRYRLTNKTGMIKLINAVNGNIRNTKRLVQFNKVCILLGIDFIYPIKLTKDNSWFVGFFDADGTINYSFKNNHPQLTISVTNKYLQDVQEYKNILGGNIYFDKSQNGYYKWSIQSKDMVLNFINDYIKMNPSRTTKMNKLYLSKEFYNLKELKAYNKSSDSMQYKAWLNFENKWKNK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the cytochrome-c oxidase activity , endonuclease activity , heme binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0015267",
"GO-Name": "channel activity "
},
{
"GO-ID": "GO:0003677",
"GO-Name": " DNA binding "
},
{
"GO-ID": "GO:0005198",
"GO-Name": " structural molecule activity "
}
] |
MGAALALLGDLVASVSEAAAATGFSVAEIAAGEAAAAIEVQIASLATVEGITSTSEAIAAIGLTPQTYAVIAGAPGAIAGFAALIQTVSGISSLAQVGYRFFSDWDHKVSTVGLYQQSGMALELFNPDEYYDILFPGVNTFVNNIQYLDPRHWGPSLFATISQALWHVIRDDIPSITSQELQRRTERFFRDSLARFLEETTWTIVNAPINFYNYIQQYYSDLSPIRPSMVRQVAEREGTRVHFGHTYSIDDADSIEEVTQRMDLRNQQSVHSGEFIEKTIAPGGANQRTAPQWMLPLLLGLYGTVTPALEAYEDGPNQKKRRVSRGSSQKAKGTRASAKTTNKRRSRSSRS
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the channel activity , DNA binding , structural molecule activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0015288",
"GO-Name": "porin activity "
}
] |
MKKTAIAITVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIDNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKAHNNVTGESEKNHDTGVSPVFAGGVEWAITPEIATRLEYQWTNNIGDAHTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the porin activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0015288",
"GO-Name": "porin activity "
}
] |
MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYMSDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQFDFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNKLNINNDDIVAVGMTYQF
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the porin activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005524",
"GO-Name": "ATP binding "
},
{
"GO-ID": "GO:0004691",
"GO-Name": " cAMP-dependent protein kinase activity "
},
{
"GO-ID": "GO:0000287",
"GO-Name": " magnesium ion binding "
},
{
"GO-ID": "GO:0030145",
"GO-Name": " manganese ion binding "
},
{
"GO-ID": "GO:0019904",
"GO-Name": " protein domain specific binding "
},
{
"GO-ID": "GO:0034237",
"GO-Name": " protein kinase A regulatory subunit binding "
},
{
"GO-ID": "GO:0004672",
"GO-Name": " protein kinase activity "
},
{
"GO-ID": "GO:0019901",
"GO-Name": " protein kinase binding "
},
{
"GO-ID": "GO:0106310",
"GO-Name": " protein serine kinase activity "
},
{
"GO-ID": "GO:0004674",
"GO-Name": " protein serine/threonine kinase activity "
},
{
"GO-ID": "GO:0004712",
"GO-Name": " protein serine/threonine/tyrosine kinase activity "
},
{
"GO-ID": "GO:0031625",
"GO-Name": " ubiquitin protein ligase binding "
}
] |
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the ATP binding , cAMP-dependent protein kinase activity , magnesium ion binding , manganese ion binding , protein domain specific binding , protein kinase A regulatory subunit binding , protein kinase activity , protein kinase binding , protein serine kinase activity , protein serine/threonine kinase activity , protein serine/threonine/tyrosine kinase activity , ubiquitin protein ligase binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0051015",
"GO-Name": "actin filament binding "
},
{
"GO-ID": "GO:0005509",
"GO-Name": " calcium ion binding "
},
{
"GO-ID": "GO:0048306",
"GO-Name": " calcium-dependent protein binding "
},
{
"GO-ID": "GO:0042803",
"GO-Name": " protein homodimerization activity "
},
{
"GO-ID": "GO:0031013",
"GO-Name": " troponin I binding "
},
{
"GO-ID": "GO:0031014",
"GO-Name": " troponin T binding "
}
] |
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the actin filament binding , calcium ion binding , calcium-dependent protein binding , protein homodimerization activity , troponin I binding , troponin T binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003925",
"GO-Name": "G protein activity "
},
{
"GO-ID": "GO:0005525",
"GO-Name": " GTP binding "
}
] |
MPAARAAPAADEPMRDPVAPVRAPALPRPAPGAVAPASGGARAPGLAAPVEAMTEYKLVVVGARGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTTGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAGRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the G protein activity , GTP binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008083",
"GO-Name": "growth factor activity "
},
{
"GO-ID": "GO:0008289",
"GO-Name": " lipid binding "
},
{
"GO-ID": "GO:0008191",
"GO-Name": " metalloendopeptidase inhibitor activity "
},
{
"GO-ID": "GO:0005163",
"GO-Name": " nerve growth factor receptor binding "
},
{
"GO-ID": "GO:0030297",
"GO-Name": " transmembrane receptor protein tyrosine kinase activator activity "
}
] |
MSMLFYTLITAFLIGIQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the growth factor activity , lipid binding , metalloendopeptidase inhibitor activity , nerve growth factor receptor binding , transmembrane receptor protein tyrosine kinase activator activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0008083",
"GO-Name": "growth factor activity "
},
{
"GO-ID": "GO:0008289",
"GO-Name": " lipid binding "
},
{
"GO-ID": "GO:0008191",
"GO-Name": " metalloendopeptidase inhibitor activity "
},
{
"GO-ID": "GO:0005163",
"GO-Name": " nerve growth factor receptor binding "
},
{
"GO-ID": "GO:0030297",
"GO-Name": " transmembrane receptor protein tyrosine kinase activator activity "
}
] |
MSMLFYTLITAFLIGVQAEPYTDSNVPEGDSVPEAHWTKLQHSLDTALRRARSAPTAPIAARVTGQTRNITVDPRLFKKRRLHSPRVLFSTQPPPTSSDTLDLDFQAHGTIPFNRTHRSKRSSTHPVFHMGEFSVCDSVSVWVGDKTTATDIKGKEVTVLAEVNINNSVFRQYFFETKCRASNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDEKQAAWRFIRIDTACVCVLSRKATRRG
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the growth factor activity , lipid binding , metalloendopeptidase inhibitor activity , nerve growth factor receptor binding , transmembrane receptor protein tyrosine kinase activator activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005542",
"GO-Name": "folic acid binding "
},
{
"GO-ID": "GO:0061714",
"GO-Name": " folic acid receptor activity "
},
{
"GO-ID": "GO:0038023",
"GO-Name": " signaling receptor activity "
}
] |
MAWQMTQLLLLALVAAAWGAQAPRTPRARTDLLNVCMDAKHHKAEPGPEDSLHEQCSPWRKNACCSVNTSIEAHKDISYLYRFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIREVNQRWRKERVLGVPLCKEDCQSWWEDCRTSYTCKSNWHKGWNWTSGYNQCPVKAACHRFDFYFPTPAALCNEIWSHSYKVSNYSRGSGRCIQMWFDPFQGNPNEEVARFYAENPTSGSTPQGI
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the folic acid binding , folic acid receptor activity , signaling receptor activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003968",
"GO-Name": "RNA-directed RNA polymerase activity "
}
] |
MEKFAPEFHGEDANNRATKFLESIKGKFTSPKDPKKKDSIISVNSIDIEVTKESPITSNSTIINPTNETDDTAGNKPNYQRKPLVSFKEDPTPSDNPFSKLYKETIETFDNNEEESSYSYEEINDQTNDNITARLDRIDEKLSEILGMLHTLVVASAGPTSARDGIRDAMIGLREEMIEKIRTEALMTNDRLEAMARLRNEESEKMAKDTSDEVSLNPTSEKLNNLLEGNDSDNDLSLEDF
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the RNA-directed RNA polymerase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0010181",
"GO-Name": "FMN binding "
}
] |
MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDLPASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAIDKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWVNLLK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the FMN binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005179",
"GO-Name": "hormone activity "
},
{
"GO-ID": "GO:0042562",
"GO-Name": " hormone binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0140313",
"GO-Name": " molecular sequestering activity "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
},
{
"GO-ID": "GO:0036094",
"GO-Name": " small molecule binding "
},
{
"GO-ID": "GO:0070324",
"GO-Name": " thyroid hormone binding "
}
] |
MASLRLFLLCLAGLIFASEAGPGGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTADGSWEPFASGKTAESGELHGLTTDEKFTEGVYRVELDTKSYWKALGISPFHEYAEVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the hormone activity , hormone binding , identical protein binding , molecular sequestering activity , protein-containing complex binding , small molecule binding , thyroid hormone binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0005179",
"GO-Name": "hormone activity "
},
{
"GO-ID": "GO:0042562",
"GO-Name": " hormone binding "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0140313",
"GO-Name": " molecular sequestering activity "
},
{
"GO-ID": "GO:0044877",
"GO-Name": " protein-containing complex binding "
}
] |
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the hormone activity , hormone binding , identical protein binding , molecular sequestering activity , protein-containing complex binding required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0042056",
"GO-Name": "chemoattractant activity "
},
{
"GO-ID": "GO:0005518",
"GO-Name": " collagen binding "
},
{
"GO-ID": "GO:0008083",
"GO-Name": " growth factor activity "
},
{
"GO-ID": "GO:0042802",
"GO-Name": " identical protein binding "
},
{
"GO-ID": "GO:0048407",
"GO-Name": " platelet-derived growth factor binding "
},
{
"GO-ID": "GO:0005161",
"GO-Name": " platelet-derived growth factor receptor binding "
},
{
"GO-ID": "GO:0046982",
"GO-Name": " protein heterodimerization activity "
},
{
"GO-ID": "GO:0042803",
"GO-Name": " protein homodimerization activity "
},
{
"GO-ID": "GO:0016176",
"GO-Name": " superoxide-generating NADPH oxidase activator activity "
}
] |
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the chemoattractant activity , collagen binding , growth factor activity , identical protein binding , platelet-derived growth factor binding , platelet-derived growth factor receptor binding , protein heterodimerization activity , protein homodimerization activity , superoxide-generating NADPH oxidase activator activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0003677",
"GO-Name": "DNA binding "
},
{
"GO-ID": "GO:0016888",
"GO-Name": " endodeoxyribonuclease activity, producing 5'-phosphomonoesters "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0000166",
"GO-Name": " nucleotide binding "
},
{
"GO-ID": "GO:0016779",
"GO-Name": " nucleotidyltransferase activity "
},
{
"GO-ID": "GO:0005198",
"GO-Name": " structural molecule activity "
}
] |
MASSSSNRQFSHRNANTFLTYPKCPENPEIACQMIWELVVRWIPKYILCAREAHKDGSLHLHALLQTEKPVRISDSRFFDINGFHPNIQSAKSVNRVRDYILKEPLAVFERGTFIPRKSPFLGKSDSEVKEKKPSKDEIMRDIISHSTSKEEYLSMIQKELPFDWSTKLQYFEYSANKLFPEIQEEFTNPHPPSSPDLLCNESINDWLQPNIFQVSPEAYMLLQPACYTLDDAISDLQWMDSVSSHQMKDQESRASTSSAQQEQENLLGPEA
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the DNA binding , endodeoxyribonuclease activity, producing 5'-phosphomonoesters , metal ion binding , nucleotide binding , nucleotidyltransferase activity , structural molecule activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0016787",
"GO-Name": "hydrolase activity "
},
{
"GO-ID": "GO:0008933",
"GO-Name": " peptidoglycan lytic transglycosylase activity "
}
] |
MDKYDKNVPSDYDGLFQKAADANGVSYDLLRKVAWTESRFVPTAKSKTGPLGMMQFTKATAKALGLRVTDGPDDDRLNPELAINAAAKQLAGLVGKFDGDELKAALAYNQGEGRLGNPQLEAYSKGDFASISEEGRNYMRNLLDVAKSPMAGQLETFGGITPKGKGIPAEVGLAGIGHKQKVTQELPESTSFDVKGIEQEATAKPFAKDFWETHGETLDEYNSRSTFFGFKNAAEAELSNSVAGMAFRAGRLDNGFDVFKDTITPTRWNSHIWTPEELEKIRTEVKNPAYINVVTGGSPENLDDLIKLANENFENDSRAAEAGLGAKLSAGIIGAGVDPLSYVPMVGVTGKGFKLINKALVVGAESAALNVASEGLRTSVAGGDADYAGAALGGFVFGAGMSAISDAVAAGLKRSKPEAEFDNEFIGPMMRLEARETARNANSADLSRMNTENMKFEGEHNGVPYEDLPTERGAVVLHDGSVLSASNPINPKTLKEFSEVDPEKAARGIKLAGFTEIGLKTLGSDDADIRRVAIDLVRSPTGMQSGASGKFGATASDIHERLHGTDQRTYNDLYKAMSDAMKDPEFSTGGAKMSREETRYTIYRRAALAIERPELQKALTPSERIVMDIIKRHFDTKRELMENPAIFGNTKAVSIFPESRHKGTYVPHVYDRHAKALMIQRYGAEGLQEGIARSWMNSYVSRPEVKARVDEMLKELHGVKEVTPEMVEKYAMDKAYGISHSDQFTNSSIIEENIEGLVGIENNSFLEARNLFDSDLSITMPDGQQFSVNDLRDFDMFRIMPAYDRRVNGDIAIMGSTGKTTKELKDEILALKAKAEGDGKKTGEVHALMDTVKILTGRARRNQDTVWETSLRAINDLGFFAKNAYMGAQNITEIAGMIVTGNVRALGHGIPILRDTLYKSKPVSAKELKELHASLFGKEVDQLIRPKRADIVQRLREATDTGPAVANIVGTLKYSTQELAARSPWTKLLNGTTNYLLDAARQGMLGDVISATLTGKTTRWEKEGFLRGASVTPEQMAGIKSLIKEHMVRGEDGKFTVKDKQAFSMDPRAMDLWRLADKVADEAMLRPHKVSLQDSHAFGALGKMVMQFKSFTIKSLNSKFLRTFYDGYKNNRAIDAALSIITSMGLAGGFYAMAAHVKAYALPKEKRKEYLERALDPTMIAHAALSRSSQLGAPLAMVDLVGGVLGFESSKMARSTILPKDTVKERDPNKPYTSREVMGAMGSNLLEQMPSAGFVANVGATLMNAAGVVNSPNKATEQDFMTGLMNSTKELVPNDPLTQQLVLKIYEANGVNLRERRK
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the hydrolase activity , peptidoglycan lytic transglycosylase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
VEWTDAERSAIIGLWGKLNPDELGPQALARCLIVYPWTQRYFATFGNLSSPAAIMGNPKVAAHGRTVMGGLERAIKNMDNIKATYAPLSVMHSEKLHVDPDNFRLLADCITVCAAMKFGPSGFNADVQEAWQKFLSVVVSALCRQYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
[
{
"GO-ID": "GO:0031720",
"GO-Name": "haptoglobin binding "
},
{
"GO-ID": "GO:0020037",
"GO-Name": " heme binding "
},
{
"GO-ID": "GO:0046872",
"GO-Name": " metal ion binding "
},
{
"GO-ID": "GO:0043177",
"GO-Name": " organic acid binding "
},
{
"GO-ID": "GO:0019825",
"GO-Name": " oxygen binding "
},
{
"GO-ID": "GO:0005344",
"GO-Name": " oxygen carrier activity "
},
{
"GO-ID": "GO:0004601",
"GO-Name": " peroxidase activity "
}
] |
VEWTDAERSAIIALWGKLNPDELGPEALARCLIVYPWTQRFFASYGNLSSPAAIMGNPKVAAHGRTVEGGLMRAIKDMDNIKATYAPLSVMHSEKLHVDPDNFRLLADCITVCAAMKFGPSGFSPNVQEAWQKFLSVVVNALKRQYH
|
Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein must be able to perform the haptoglobin binding , heme binding , metal ion binding , organic acid binding , oxygen binding , oxygen carrier activity , peroxidase activity required for its activity.. The designed protein sequence is
|
End of preview.
SwissIPG
SwissProt-based Protein Function (InterPro and Gene Ontology) Benchmark Datasets
This repository provides benchmark datasets for protein function evaluation, constructed from UniProt/SwissProt, InterPro (IPR), and Gene Ontology (GO).
It includes both test sets and training sets, supporting keyword-guided and description-guided protein design/evaluation tasks.
📖 Dataset Overview
Keyword-guided protein tasks previously lacked a publicly available, high-quality evaluation dataset. To address this gap, we curated a novel dataset from SwissProt, together with their IPR entries and GO terms. Note that the GO terms are restricted to Molecular Function (MF).
| Subset | Num of Proteins | Num of IPR entries | Num of GO terms |
|---|---|---|---|
| Test Set | 1,057 | 1,297 | 380 |
| Train Set | 555543 | 39431 | 8110 |
🔧 Dataset Construction
Protein selection Extracted proteins from UniProt/SwissProt released between
2025-01-01and2025-08-25for testing. The remaining proteins are used for training.Keyword collection Retrieved corresponding protein sequences, InterPro IDs, and GO terms.
Instruction construction for description-guided task Following Mol-Instructions, we concatenated text descriptions of InterPro entries and GO terms to form natural-language prompts.
| Keyword | Description |
|---|---|
| InterPro (Domain) | The protein should contain one or more {} that are essential for its biological function |
| InterPro (Family) | The protein should belong to {} that shares evolutionary origin and functional similarity |
| InterPro (Homologous_Superfamily) | The protein should be classified within {} sharing conserved structural features |
| InterPro (Repeat) | The protein should include one or more {} that provide structural or functional support |
| InterPro (Conserved_Site) | The protein should contain {} that is preserved across related proteins |
| InterPro (Active_Site) | The protein must have {} that is conserved among related catalytic enzymes |
| InterPro (Binding_Site) | The protein should include a {} that enables ligand binding under diverse conditions |
| InterPro (PTM) | The protein should contain {} that allow regulation through chemical modifications |
| Gene Ontology (molecular function) | The protein must be able to perform the {} required for its activity. |
- Final curation Curated into test and train sets with consistent formats.
📂 Dataset Structure
| File | Func-Seq Pairs | Description |
|---|---|---|
go_test.json |
693 | Test set for GO task. |
go_train.json |
492124 | Train set for GO task. |
ipr_test.json |
870 | Test set for IPR task. |
ipr_train.json |
555543 | Train set for IPR task. |
ipr_go_test.json |
674 | Test set for IPR&GO task. |
ipr_go_train.json |
487848 | Train set for IPR&GO task. |
SwissIPG.py |
- | Building Class |
🎯 Intended Use
- Benchmarking protein design models under keyword-guided and description-guided settings
- Training and fine-tuning models using consistent annotation standards
- Facilitating fair comparison across models through a unified dataset
🔍 Evaluation Metrics
Our work, PDFBench, provides a comprehensive evaluation for both tasks. For further details, please refer to the repository.
📑 Citation
If you use this dataset, please cite:
@misc{kuang2025pdfbenchbenchmarknovoprotein,
title={PDFBench: A Benchmark for De novo Protein Design from Function},
author={Jiahao Kuang and Nuowei Liu and Changzhi Sun and Tao Ji and Yuanbin Wu},
year={2025},
eprint={2505.20346},
archivePrefix={arXiv},
primaryClass={cs.LG},
url={https://arxiv.org/abs/2505.20346},
}
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